BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0073.p (575 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J233.1 D8J233_HERSS Dihydroxyacid dehydratase/phosphogluconate... 1061 0.0 C5CU92.1 C5CU92_VARPS Dihydroxy-acid dehydratase EC=4.2.1.9 936 0.0 E6V880.1 E6V880_VARPD Dihydroxy-acid dehydratase EC=4.2.1.9 907 0.0 Q126V2.1 Q126V2_POLSJ Dihydroxyacid dehydratase EC=4.2.1.9 895 0.0 B1G3V2.1 B1G3V2_9BURK Dihydroxy-acid dehydratase EC=4.2.1.9 891 0.0 >D8J233.1 D8J233_HERSS Dihydroxyacid dehydratase/phosphogluconate dehydratase protein EC=4.2.1.9 Length = 578 Score = 1061 bits (2743), Expect = 0.0, Method: Compositional matrix adjust. Identities = 504/575 (87%), Positives = 544/575 (94%), Gaps = 2/575 (0%) Query: 3 DTKTFTRRSQAWFGRQDRDGFIYRSWVKNRGIPHDQFDGRPVIGICNTYSELTPCNSHFR 62 DTK TRRSQAWFGRQDRDGFIYRSWVKNRGIPHDQFDGRPVIGICNTYSELTPCNSHFR Sbjct: 4 DTKKSTRRSQAWFGRQDRDGFIYRSWVKNRGIPHDQFDGRPVIGICNTYSELTPCNSHFR 63 Query: 63 ALAEQVKIGIWEAGGFPLEFPVMSLGETLMRPTAMLFRNLASMDVEESIRANPLDGVVLL 122 ALAEQVKIGIWEAGGFPLEFPVMSLGETL+RPTAML+RNLASMDVEESIRANPLDGVVLL Sbjct: 64 ALAEQVKIGIWEAGGFPLEFPVMSLGETLLRPTAMLYRNLASMDVEESIRANPLDGVVLL 123 Query: 123 MGCDKTTPALLMGASSVDLPTIGISGGPMLSGKYRGGELGSGTGVWQMSEEVRAGQMSQE 182 MGCDKTTPALLMGA+SVD+PTIG+SGGPMLSGKYRG ELGSGTGVWQMSE+VRAG+M+QE Sbjct: 124 MGCDKTTPALLMGAASVDVPTIGVSGGPMLSGKYRGRELGSGTGVWQMSEDVRAGKMTQE 183 Query: 183 EFFEAESCMHRSHGHCMTMGTASTMASMVEALGMSLPGNAAIPAVDARRNVLARNSGRRI 242 EFFEAESCMHRSHGHCMTMGTASTMASMVEALG+ LP NAAIPAVDARRNVLARN+GRRI Sbjct: 184 EFFEAESCMHRSHGHCMTMGTASTMASMVEALGVGLPHNAAIPAVDARRNVLARNAGRRI 243 Query: 243 VEMVKEDLIMSRILTKAAFENAIRVNAGIGGSTNAVIHLLAIAGRIGVDLKLEEWDKIGQ 302 V+MV+EDL++S+ILT+ AFENAIRVNA IGGSTNAVIHLLAIAGRIG+ L L++WD IGQ Sbjct: 244 VQMVEEDLVLSKILTRQAFENAIRVNAAIGGSTNAVIHLLAIAGRIGIKLDLKDWDDIGQ 303 Query: 303 KLPCLVNLQPSGKYLMEDFYYAGGLPSVIRELESVIDKSALSANGQTLWDNCKDAPNWNR 362 +LPCL++LQPSGK+LMEDFYYAGGLP+VIR+LESVIDK+AL+ANG+TLW+NC+DAPNWN Sbjct: 304 QLPCLLDLQPSGKFLMEDFYYAGGLPAVIRQLESVIDKTALTANGKTLWENCQDAPNWNE 363 Query: 363 DVIHAFDTPFKAAAGIAILHGNLCPDGAVIKPSAATPALLKHTGRAVVFENSDDLHKRID 422 +VI +FD PFK AAGIAIL GNL PDGAVIKPSAATPALLKH GRAVVFENSDDLHKRID Sbjct: 364 EVIRSFDKPFKEAAGIAILKGNLAPDGAVIKPSAATPALLKHRGRAVVFENSDDLHKRID 423 Query: 423 DENLDVDENCVLVLKNCGPKGYPGMGEAGNMPLPPKVLRKGITDMVRVSDARMSGTAYGT 482 DENLDVDE CVLVLKNCGPKGYPGM EAGNMPLPPK+LRKGITDMVRVSDARMSGTAYGT Sbjct: 424 DENLDVDETCVLVLKNCGPKGYPGMAEAGNMPLPPKILRKGITDMVRVSDARMSGTAYGT 483 Query: 483 VVLHVTPEAAAGGPLALVQDGDLVELDVDARKLHLHVSDEELARRRALWQAPKAPA--DR 540 VVLHV+PEAAAGGPLA+VQ+GD +ELDV+ARKLHL VSDEELARRRA WQ P+ P R Sbjct: 484 VVLHVSPEAAAGGPLAVVQNGDFIELDVEARKLHLDVSDEELARRRAQWQKPELPPQMQR 543 Query: 541 GWVKLYVDHVQQANLGADLDFLVGKSGSGIPKDNH 575 GWVKLYVDHVQQAN GADLDFLVGKSG +PKDNH Sbjct: 544 GWVKLYVDHVQQANQGADLDFLVGKSGPYVPKDNH 578 >C5CU92.1 C5CU92_VARPS Dihydroxy-acid dehydratase EC=4.2.1.9 Length = 578 Score = 936 bits (2420), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/566 (78%), Positives = 499/566 (88%) Query: 10 RSQAWFGRQDRDGFIYRSWVKNRGIPHDQFDGRPVIGICNTYSELTPCNSHFRALAEQVK 69 RSQ WFGR DRDGFIYRSWVK +G+PHDQFDGRPVIGICNT+SELTPCNSHFR LAEQVK Sbjct: 13 RSQQWFGRHDRDGFIYRSWVKGKGVPHDQFDGRPVIGICNTFSELTPCNSHFRTLAEQVK 72 Query: 70 IGIWEAGGFPLEFPVMSLGETLMRPTAMLFRNLASMDVEESIRANPLDGVVLLMGCDKTT 129 IG++EAGGFPLEFPVMSLGETL+RPTAML+RNLASMDVEESIR NPLDGVVLLMGCDKTT Sbjct: 73 IGVYEAGGFPLEFPVMSLGETLLRPTAMLYRNLASMDVEESIRGNPLDGVVLLMGCDKTT 132 Query: 130 PALLMGASSVDLPTIGISGGPMLSGKYRGGELGSGTGVWQMSEEVRAGQMSQEEFFEAES 189 PAL+MGA+SVDLPTIG+SGGPMLSGK+RG ELGSGTGVWQMSE+VRAG + ++FFEAES Sbjct: 133 PALMMGAASVDLPTIGVSGGPMLSGKWRGQELGSGTGVWQMSEQVRAGTLKLQDFFEAES 192 Query: 190 CMHRSHGHCMTMGTASTMASMVEALGMSLPGNAAIPAVDARRNVLARNSGRRIVEMVKED 249 CMHRSHGHCMTMGTASTMASMVE+LG+ LPGNAA PAVD RRNVLAR +GRRIV+MV ED Sbjct: 193 CMHRSHGHCMTMGTASTMASMVESLGIGLPGNAAYPAVDGRRNVLARMAGRRIVDMVHED 252 Query: 250 LIMSRILTKAAFENAIRVNAGIGGSTNAVIHLLAIAGRIGVDLKLEEWDKIGQKLPCLVN 309 L MS+ILT+ A ENAI+VNA IGGSTN VIHLLAIAGRIGVDL L+++D++ LPCLV+ Sbjct: 253 LHMSKILTRQAIENAIKVNAAIGGSTNLVIHLLAIAGRIGVDLSLDDFDRLASDLPCLVD 312 Query: 310 LQPSGKYLMEDFYYAGGLPSVIRELESVIDKSALSANGQTLWDNCKDAPNWNRDVIHAFD 369 LQPSG++LMEDF YAGGLP VI+E+ + K ++ANGQTLWDN KDA N+N VI Sbjct: 313 LQPSGRFLMEDFCYAGGLPVVIKEIAQYLHKDVITANGQTLWDNVKDAENYNPQVIRPLA 372 Query: 370 TPFKAAAGIAILHGNLCPDGAVIKPSAATPALLKHTGRAVVFENSDDLHKRIDDENLDVD 429 PFK AGI +L GNL P+GA+IKPSAATP LL H GRAVVFE++DDLHKRIDDENLD+D Sbjct: 373 EPFKDKAGICVLRGNLAPNGAIIKPSAATPELLVHKGRAVVFESADDLHKRIDDENLDID 432 Query: 430 ENCVLVLKNCGPKGYPGMGEAGNMPLPPKVLRKGITDMVRVSDARMSGTAYGTVVLHVTP 489 E+CV+VLKNCGP+GYPGM E+GNMPLPPKVLRKGITDMVR+SDARMSGTAYGTVVLH P Sbjct: 433 EHCVMVLKNCGPRGYPGMAESGNMPLPPKVLRKGITDMVRISDARMSGTAYGTVVLHTAP 492 Query: 490 EAAAGGPLALVQDGDLVELDVDARKLHLHVSDEELARRRALWQAPKAPADRGWVKLYVDH 549 EAAAGGPLALVQDGD+VELDV RKLHLHVSDEELARR W APKAP D G+ KLYVD Sbjct: 493 EAAAGGPLALVQDGDIVELDVPNRKLHLHVSDEELARRLEKWVAPKAPLDSGYWKLYVDT 552 Query: 550 VQQANLGADLDFLVGKSGSGIPKDNH 575 V QA+ GADL FL G+ G+ +P+DNH Sbjct: 553 VLQADQGADLAFLRGRRGAFVPRDNH 578 >E6V880.1 E6V880_VARPD Dihydroxy-acid dehydratase EC=4.2.1.9 Length = 578 Score = 907 bits (2343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/566 (77%), Positives = 497/566 (87%) Query: 10 RSQAWFGRQDRDGFIYRSWVKNRGIPHDQFDGRPVIGICNTYSELTPCNSHFRALAEQVK 69 RSQ WFGR DRDGFIYRSW+K +G+PHDQFDGRPVIGICNT+SELTPCNSHFR LAEQVK Sbjct: 13 RSQQWFGRHDRDGFIYRSWMKGKGVPHDQFDGRPVIGICNTFSELTPCNSHFRTLAEQVK 72 Query: 70 IGIWEAGGFPLEFPVMSLGETLMRPTAMLFRNLASMDVEESIRANPLDGVVLLMGCDKTT 129 IG++EAGGFPLEFPVMSLGETL+RPTAML+RNLASMDVEESIR NPLDGVVLLMGCDKTT Sbjct: 73 IGVYEAGGFPLEFPVMSLGETLLRPTAMLYRNLASMDVEESIRGNPLDGVVLLMGCDKTT 132 Query: 130 PALLMGASSVDLPTIGISGGPMLSGKYRGGELGSGTGVWQMSEEVRAGQMSQEEFFEAES 189 PAL+MGA+SVDLPTIG+SGGPMLSGK+RG ELGSGTGVWQMSE+VRAG + ++FFEAES Sbjct: 133 PALMMGAASVDLPTIGVSGGPMLSGKWRGQELGSGTGVWQMSEQVRAGTLKLQDFFEAES 192 Query: 190 CMHRSHGHCMTMGTASTMASMVEALGMSLPGNAAIPAVDARRNVLARNSGRRIVEMVKED 249 CMHRSHGHCMTMGTASTMA MVEALG+ LPGNAA PAVD RRNVLAR +GRRIV+MV ED Sbjct: 193 CMHRSHGHCMTMGTASTMACMVEALGIGLPGNAAYPAVDGRRNVLARQAGRRIVDMVHED 252 Query: 250 LIMSRILTKAAFENAIRVNAGIGGSTNAVIHLLAIAGRIGVDLKLEEWDKIGQKLPCLVN 309 + MS+ILT+ A ENAI+VNA +GGSTN VIHLLAIAGRIGVDL L+++D++ +LPCLVN Sbjct: 253 MNMSKILTRQAIENAIKVNAAVGGSTNLVIHLLAIAGRIGVDLTLDDFDRLASELPCLVN 312 Query: 310 LQPSGKYLMEDFYYAGGLPSVIRELESVIDKSALSANGQTLWDNCKDAPNWNRDVIHAFD 369 LQPSG++LMEDF YAGGLP VI+E+ + K L+ GQ+LWDN KDA N+ VI Sbjct: 313 LQPSGQFLMEDFCYAGGLPVVIKEIAEHLHKDILTVTGQSLWDNVKDAENYGPQVIRPLA 372 Query: 370 TPFKAAAGIAILHGNLCPDGAVIKPSAATPALLKHTGRAVVFENSDDLHKRIDDENLDVD 429 PFK AGI +L GNL P+GA+IKPSAATP LL H GRAVVFE++DDLHKRIDDE+LD+D Sbjct: 373 EPFKENAGICVLRGNLAPNGAIIKPSAATPELLVHKGRAVVFESADDLHKRIDDEDLDID 432 Query: 430 ENCVLVLKNCGPKGYPGMGEAGNMPLPPKVLRKGITDMVRVSDARMSGTAYGTVVLHVTP 489 E+C++VLKNCGPKGYPGM EAGNMPLPPKVLRKGITDMVR+SDARMSGTAYGTVVLH P Sbjct: 433 EHCIMVLKNCGPKGYPGMAEAGNMPLPPKVLRKGITDMVRISDARMSGTAYGTVVLHTAP 492 Query: 490 EAAAGGPLALVQDGDLVELDVDARKLHLHVSDEELARRRALWQAPKAPADRGWVKLYVDH 549 EAAAGGPLALVQ+GD+VELDV RKLHLHVSDEELA+RR W APKAP D G+ KLYVD Sbjct: 493 EAAAGGPLALVQNGDIVELDVPNRKLHLHVSDEELAKRREKWVAPKAPLDSGYWKLYVDT 552 Query: 550 VQQANLGADLDFLVGKSGSGIPKDNH 575 V QA+ GADL FL G+ G+ +P+DNH Sbjct: 553 VLQADQGADLAFLRGRRGAFVPRDNH 578 >Q126V2.1 Q126V2_POLSJ Dihydroxyacid dehydratase EC=4.2.1.9 Length = 579 Score = 895 bits (2314), Expect = 0.0, Method: Compositional matrix adjust. Identities = 431/566 (76%), Positives = 492/566 (86%) Query: 10 RSQAWFGRQDRDGFIYRSWVKNRGIPHDQFDGRPVIGICNTYSELTPCNSHFRALAEQVK 69 RSQ WFGRQDRDGF YRSWVK +G+PHDQFDGRPVIGICNT+SELTPCNSHFR +AEQVK Sbjct: 14 RSQQWFGRQDRDGFAYRSWVKGKGVPHDQFDGRPVIGICNTFSELTPCNSHFRTIAEQVK 73 Query: 70 IGIWEAGGFPLEFPVMSLGETLMRPTAMLFRNLASMDVEESIRANPLDGVVLLMGCDKTT 129 IG++EAGGFPLEFPVMSLGETL+RPTAML+RNLASMDVEESIR NP+DGVVLLMGCDKTT Sbjct: 74 IGVYEAGGFPLEFPVMSLGETLLRPTAMLYRNLASMDVEESIRGNPIDGVVLLMGCDKTT 133 Query: 130 PALLMGASSVDLPTIGISGGPMLSGKYRGGELGSGTGVWQMSEEVRAGQMSQEEFFEAES 189 P+L+MGASSVDLPT+G+SGGPMLSGK+RG ELGSGTGVW MSE+VRAG + ++FFEAES Sbjct: 134 PSLVMGASSVDLPTVGVSGGPMLSGKWRGQELGSGTGVWSMSEQVRAGTLKLQDFFEAES 193 Query: 190 CMHRSHGHCMTMGTASTMASMVEALGMSLPGNAAIPAVDARRNVLARNSGRRIVEMVKED 249 CMHRSHGHCMTMGTASTMASMVEALG+ LPGNAA PAVD RRNVLAR +GRR VEMV ED Sbjct: 194 CMHRSHGHCMTMGTASTMASMVEALGIGLPGNAAYPAVDGRRNVLARLAGRRAVEMVHED 253 Query: 250 LIMSRILTKAAFENAIRVNAGIGGSTNAVIHLLAIAGRIGVDLKLEEWDKIGQKLPCLVN 309 L +S+ILT+ AFENAI+ A IGGSTNAVIHL+AIAGRIGV L ++++D++ +LPCLVN Sbjct: 254 LTLSKILTREAFENAIKTLAAIGGSTNAVIHLIAIAGRIGVKLTVDDFDRLASELPCLVN 313 Query: 310 LQPSGKYLMEDFYYAGGLPSVIRELESVIDKSALSANGQTLWDNCKDAPNWNRDVIHAFD 369 LQPSGKYLMEDF YAGGLP V++E+ + A++ANG+T+ +N DA N+N DVI Sbjct: 314 LQPSGKYLMEDFCYAGGLPVVMKEIAQHLHTDAITANGKTIGENIADAENYNTDVIMPLS 373 Query: 370 TPFKAAAGIAILHGNLCPDGAVIKPSAATPALLKHTGRAVVFENSDDLHKRIDDENLDVD 429 TPFK AGIA+L GNL P GAVIKPSAATP L+ H GRAVVFE +D H RIDDE+LD+D Sbjct: 374 TPFKDKAGIAVLRGNLSPRGAVIKPSAATPELMVHKGRAVVFETIEDFHARIDDEDLDID 433 Query: 430 ENCVLVLKNCGPKGYPGMGEAGNMPLPPKVLRKGITDMVRVSDARMSGTAYGTVVLHVTP 489 E CV+VLKNCGPKGYPGM E GNMPLPPKVLRKGITDMVR+SDARMSGTAYGTVVLH P Sbjct: 434 ETCVMVLKNCGPKGYPGMAEVGNMPLPPKVLRKGITDMVRISDARMSGTAYGTVVLHTAP 493 Query: 490 EAAAGGPLALVQDGDLVELDVDARKLHLHVSDEELARRRALWQAPKAPADRGWVKLYVDH 549 EAAAGGPLALVQ+GD++ELDV R+LHLHVSDEELA+R A W+AP P G+ KLY+DH Sbjct: 494 EAAAGGPLALVQNGDIIELDVPNRRLHLHVSDEELAKRMADWKAPAPPLTSGYWKLYIDH 553 Query: 550 VQQANLGADLDFLVGKSGSGIPKDNH 575 V QA+ G DLDFLVGK G+ +P+DNH Sbjct: 554 VLQADEGVDLDFLVGKRGAFVPRDNH 579 >B1G3V2.1 B1G3V2_9BURK Dihydroxy-acid dehydratase EC=4.2.1.9 Length = 577 Score = 891 bits (2303), Expect = 0.0, Method: Compositional matrix adjust. Identities = 421/579 (72%), Positives = 501/579 (86%), Gaps = 6/579 (1%) Query: 1 MSDTKTFTR--RSQAWFGRQDRDGFIYRSWVKNRGIPHDQFDGRPVIGICNTYSELTPCN 58 M+D+ + RSQAWFG +DRDGF++RSW+KN+GIPHD+FDGRPVIGICNT+SELTPCN Sbjct: 1 MADSNQTKKPLRSQAWFGLKDRDGFLHRSWMKNQGIPHDEFDGRPVIGICNTWSELTPCN 60 Query: 59 SHFRALAEQVKIGIWEAGGFPLEFPVMSLGETLMRPTAMLFRNLASMDVEESIRANPLDG 118 +HFR LAE VK G+ EAGG PLEFPVMSLGET +RPTAMLFRNLASMDVEESIR NP+DG Sbjct: 61 AHFRELAEYVKKGVHEAGGLPLEFPVMSLGETNLRPTAMLFRNLASMDVEESIRGNPMDG 120 Query: 119 VVLLMGCDKTTPALLMGASSVDLPTIGISGGPMLSGKYRGGELGSGTGVWQMSEEVRAGQ 178 V+LL+GCDKTTPALLMGA+S +LP++ +SGGPML+G++RG +GSGTGVWQMSEEVRAG Sbjct: 121 VILLVGCDKTTPALLMGAASCNLPSLAVSGGPMLNGRFRGKHIGSGTGVWQMSEEVRAGT 180 Query: 179 MSQEEFFEAESCMHRSHGHCMTMGTASTMASMVEALGMSLPGNAAIPAVDARRNVLARNS 238 M+QEEF EAESCM+RS GHCMTMGTASTMASMVE+LGM LP NAAIPAVDARR VLA + Sbjct: 181 MTQEEFTEAESCMNRSRGHCMTMGTASTMASMVESLGMGLPQNAAIPAVDARRQVLAHLA 240 Query: 239 GRRIVEMVKEDLIMSRILTKAAFENAIRVNAGIGGSTNAVIHLLAIAGRIGVDLKLEEWD 298 GRRIV+MV+EDL M +ILT+ AFENAIR NA IGGSTNAV+HL+A+A RIGV+L LE+W+ Sbjct: 241 GRRIVDMVREDLTMDKILTRQAFENAIRTNAAIGGSTNAVVHLIALAKRIGVELSLEDWE 300 Query: 299 KIGQKLPCLVNLQPSGKYLMEDFYYAGGLPSVIREL--ESVIDKSALSANGQTLWDNCKD 356 +G +PCLVNLQPSG+YLMEDFYYAGGLP+V+++L + ++ + AL+ NG+T+WDN ++ Sbjct: 301 -LGSNVPCLVNLQPSGEYLMEDFYYAGGLPAVLKQLGEQGLLHREALTVNGKTIWDNVRN 359 Query: 357 APNWNRDVIHAFDTPFKAAAGIAILHGNLCPDGAVIKPSAATPALLKHTGRAVVFENSDD 416 A N++ VI F PFKA AGIA+L GNL P+GAVIKPSAAT LLKH GRAVVFEN ++ Sbjct: 360 ASNYDEKVITTFAEPFKAKAGIAVLKGNLAPNGAVIKPSAATAELLKHRGRAVVFENIEE 419 Query: 417 LHKRIDDENLDVDENCVLVLKNCGPKGYPGMGEAGNMPLPPKVLRKGITDMVRVSDARMS 476 LH +IDDE LD+DENC++VLK GPKGYPG E GNMPLP KVL+KGITDMVR+SD RMS Sbjct: 420 LHAKIDDEALDIDENCIMVLKGAGPKGYPGFAEVGNMPLPKKVLQKGITDMVRISDGRMS 479 Query: 477 GTAYGTVVLHVTPEAAAGGPLALVQDGDLVELDVDARKLHLHVSDEELARRRALWQAPKA 536 GTAYG VVLHV+PEAAAGGPLALVQ GD++ELDV+AR+LHL VSDEEL RRRA WQAP+A Sbjct: 480 GTAYGAVVLHVSPEAAAGGPLALVQTGDMIELDVEARRLHLEVSDEELERRRAAWQAPEA 539 Query: 537 PADRGWVKLYVDHVQQANLGADLDFLVGKSGSGIPKDNH 575 P RG+ KLYV+HV QA+ GADLDFLVG SG+ +P+D+H Sbjct: 540 P-KRGYYKLYVEHVLQADQGADLDFLVGSSGAPVPRDSH 577