BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0058.p (770 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRL9.1 D8IRL9_HERSS DNA topoisomerase IV (Subunit A) protein E... 1367 0.0 A6SVU9.1 A6SVU9_JANMA Topoisomerase IV subunit A EC=5.99.1.- 1336 0.0 A4G394.1 A4G394_HERAR DNA topoisomerase 4 subunit A (Topoisomera... 1317 0.0 F1W2E6.1 F1W2E6_9BURK Topoisomerase IV subunit A 1263 0.0 E1TC50.1 E1TC50_BURSG DNA topoisomerase IV, A subunit EC=5.99.1.3 1129 0.0 >D8IRL9.1 D8IRL9_HERSS DNA topoisomerase IV (Subunit A) protein EC=5.99.1.- Length = 771 Score = 1367 bits (3537), Expect = 0.0, Method: Compositional matrix adjust. Identities = 658/769 (85%), Positives = 716/769 (93%), Gaps = 1/769 (0%) Query: 1 MTEQANLFEQ-PAPPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 59 MT+Q LF+Q P+ PDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA Sbjct: 1 MTDQPTLFDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 60 Query: 60 MNELGLNATAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS 119 MNEL LN+ AKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDG GNFGS Sbjct: 61 MNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFGS 120 Query: 120 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGA 179 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTV+FQPNYDGSTEEP+LLPARLPFLLLNGA Sbjct: 121 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNGA 180 Query: 180 SGIAVGMATEIPSHNLREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIA 239 SGIAVGMATEIPSHNL EVA+AAVAMIRNPKI+HAELM I GPDFPGGGQIITP +TIA Sbjct: 181 SGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATIA 240 Query: 240 EIYQSGRGSLKVRARWKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGKKT 299 E+YQSGRGSLKVRARWKIED+ARGQWQAVITELPPGVSSQ+VLEEIEELTNPK+KLGKK+ Sbjct: 241 EMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKKS 300 Query: 300 LTPEQQAQKQSILAMLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSS 359 LTPEQQAQK +IL +LDAVRDESGR+APVRLVFEPKSKNQDQTEFMNTLLAQTSLETS+S Sbjct: 301 LTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSAS 360 Query: 360 INLVMIGGDGRPRQKGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNI 419 +NLVMIGGDGRPRQK L DIL EWI+FRF T+TRR+QF++QKV DRIHILEGREA+LLNI Sbjct: 361 LNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLNI 420 Query: 420 DKVIRIIRESDEPKPALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKAT 479 DKVIRIIRESDEPKPALIEAF+LSDRQAEDILEIRLRQLARLE IKIQQELAELRNEK+T Sbjct: 421 DKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKST 480 Query: 480 LQDLLDNPASMKRLVIKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQKGW 539 LQDLLDNP+SMK+LVIKEIE D K +GDARRT+IEEAE+A EQKVIDEPVTVIISQKGW Sbjct: 481 LQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKGW 540 Query: 540 VRARGGHGHDATQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVP 599 VRAR GHGHDATQFTFKAGD LYGAFECRTVDNLL FGSNGR+YT+ VN+LPNARGDGVP Sbjct: 541 VRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGVP 600 Query: 600 ITTLVDLGNGNNLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDL 659 +TTL++L +G+++LHYFAGP DT +LLASDA GF AK DM RVKGGK+F TLDEG L Sbjct: 601 VTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGAL 660 Query: 660 PLAPRPMPAGASAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQ 719 PLAP P+P ASA+AC+SG GRLLVFGLDE+KTL+SGGRGV LMELEKNEKL+AAQAI+Q Sbjct: 661 PLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAISQ 720 Query: 720 KGVLVSGTGRGGKAQDVTLSAVALALHIGKRARKGKALESKLKATALAA 768 KGV+V GTG GKA+++ LSAV+LALHIGKRARKGKALES++K T L A Sbjct: 721 KGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLRA 769 >A6SVU9.1 A6SVU9_JANMA Topoisomerase IV subunit A EC=5.99.1.- Length = 771 Score = 1336 bits (3458), Expect = 0.0, Method: Compositional matrix adjust. Identities = 650/769 (84%), Positives = 709/769 (92%), Gaps = 1/769 (0%) Query: 1 MTEQANLFEQPAPPDG-ESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 59 MT+QANLF+Q AP DG E+LTL+TFAERAYLDYAISVVKGRALPDV DGQKPVQRRIL+A Sbjct: 1 MTDQANLFDQEAPADGGEALTLTTFAERAYLDYAISVVKGRALPDVCDGQKPVQRRILFA 60 Query: 60 MNELGLNATAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS 119 MNELGLN+ AKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS Sbjct: 61 MNELGLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS 120 Query: 120 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGA 179 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLP+RLPF+LLNGA Sbjct: 121 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPSRLPFVLLNGA 180 Query: 180 SGIAVGMATEIPSHNLREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIA 239 SGIAVGMATEIPSHNL EVA+AAVA+IRNPK+TH ELM + GPDFPGGGQIIT P+ I+ Sbjct: 181 SGIAVGMATEIPSHNLHEVAKAAVALIRNPKLTHEELMAIVPGPDFPGGGQIITSPTAIS 240 Query: 240 EIYQSGRGSLKVRARWKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGKKT 299 +IY SGRGS+KVRA WKIEDMARGQWQAV+TELP G SSQKVLEEIEELTNPKIKLGKK+ Sbjct: 241 DIYSSGRGSVKVRATWKIEDMARGQWQAVVTELPHGTSSQKVLEEIEELTNPKIKLGKKS 300 Query: 300 LTPEQQAQKQSILAMLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSS 359 L+PEQ A KQ++L+MLD VRDESGR+APVRLVFEPKSKNQDQTEF N LLA TSLETS S Sbjct: 301 LSPEQLALKQTVLSMLDTVRDESGRDAPVRLVFEPKSKNQDQTEFTNLLLAHTSLETSVS 360 Query: 360 INLVMIGGDGRPRQKGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNI 419 INLVMIGGDGRPRQK L DIL EWI FRF TITRRSQFKLQKV+DRIHILEGREAILLNI Sbjct: 361 INLVMIGGDGRPRQKSLGDILREWIEFRFTTITRRSQFKLQKVDDRIHILEGREAILLNI 420 Query: 420 DKVIRIIRESDEPKPALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKAT 479 DKVI+IIRESDEPKPAL++AF+LS+RQA+DILEIRLRQLARLETIKIQQELAELRNEK T Sbjct: 421 DKVIKIIRESDEPKPALMDAFRLSERQADDILEIRLRQLARLETIKIQQELAELRNEKTT 480 Query: 480 LQDLLDNPASMKRLVIKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQKGW 539 LQDLLDNP+SMKRLVIKEIEAD+KQFGDARRT+IE AEKA +E KVIDEPVTV+ISQKGW Sbjct: 481 LQDLLDNPSSMKRLVIKEIEADEKQFGDARRTLIEVAEKASVETKVIDEPVTVVISQKGW 540 Query: 540 VRARGGHGHDATQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVP 599 VRAR GHGHDA QFTFKAGD LY FECRTVD+LL FGSNGRIY+V V++LP ARGDGVP Sbjct: 541 VRARTGHGHDAAQFTFKAGDTLYNTFECRTVDSLLVFGSNGRIYSVPVSALPGARGDGVP 600 Query: 600 ITTLVDLGNGNNLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDL 659 ITTLV+L +G+ +LHYFAGP D +LLAS AGYGFTAK GDM+SR +GGK+FITLD+GD Sbjct: 601 ITTLVELASGSRILHYFAGPADVTLLLASTAGYGFTAKSGDMVSRTRGGKSFITLDDGDE 660 Query: 660 PLAPRPMPAGASAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQ 719 PLAP P+ AGASAIACLS +GRLLVFG+DEIK+L +GGRGVILM+LEKNEKLLAAQAI+Q Sbjct: 661 PLAPCPVTAGASAIACLSEKGRLLVFGIDEIKSLTAGGRGVILMDLEKNEKLLAAQAISQ 720 Query: 720 KGVLVSGTGRGGKAQDVTLSAVALALHIGKRARKGKALESKLKATALAA 768 +GV+VSG GRGGKAQ+V LSA LA HIGKRARKGKALESK+KAT L A Sbjct: 721 RGVIVSGAGRGGKAQEVLLSASGLAPHIGKRARKGKALESKIKATTLTA 769 >A4G394.1 A4G394_HERAR DNA topoisomerase 4 subunit A (Topoisomerase IV subunit A) EC=5.99.1.- Length = 776 Score = 1317 bits (3409), Expect = 0.0, Method: Compositional matrix adjust. Identities = 637/770 (82%), Positives = 703/770 (91%), Gaps = 1/770 (0%) Query: 1 MTEQANLFEQPAPPDG-ESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 59 MT+QANLF+ AP DG ESLTL+TFAERAYLDYAISVVKGRALPDV DGQKPVQRRIL+A Sbjct: 1 MTDQANLFDTAAPADGGESLTLATFAERAYLDYAISVVKGRALPDVCDGQKPVQRRILFA 60 Query: 60 MNELGLNATAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS 119 MNELGLN+ AKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS Sbjct: 61 MNELGLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS 120 Query: 120 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGA 179 RDGDGAAAMRYTEARLTPI+KLL++EIDMGTVDFQPNYDGSTEEPKLLP+RLPF+LLNGA Sbjct: 121 RDGDGAAAMRYTEARLTPIAKLLMEEIDMGTVDFQPNYDGSTEEPKLLPSRLPFVLLNGA 180 Query: 180 SGIAVGMATEIPSHNLREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIA 239 SGIAVGMATEIPSHNLREVA+AAVA+IRNPK+TH EL+ + GPDFPGGGQIIT P+ I+ Sbjct: 181 SGIAVGMATEIPSHNLREVAQAAVALIRNPKLTHEELVAIVPGPDFPGGGQIITSPTAIS 240 Query: 240 EIYQSGRGSLKVRARWKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGKKT 299 +IY+SGRGS+KVRA WKIEDMARGQWQAV+TELP G SSQ+VLEEIEELTNPKI+LGKK+ Sbjct: 241 DIYRSGRGSVKVRATWKIEDMARGQWQAVVTELPHGTSSQRVLEEIEELTNPKIRLGKKS 300 Query: 300 LTPEQQAQKQSILAMLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSS 359 L+PEQ A KQ++LAMLD VRDESGR+APVRLVFEPKSKNQDQTEF N LLA TSLETS S Sbjct: 301 LSPEQLALKQTVLAMLDTVRDESGRDAPVRLVFEPKSKNQDQTEFTNMLLAHTSLETSVS 360 Query: 360 INLVMIGGDGRPRQKGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNI 419 INLVMIGGDG+PRQK L DIL EW+ FRF TITRRSQFKLQKV DRIHILEGREAILLNI Sbjct: 361 INLVMIGGDGKPRQKALGDILREWVDFRFTTITRRSQFKLQKVNDRIHILEGREAILLNI 420 Query: 420 DKVIRIIRESDEPKPALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKAT 479 DKVI+IIRESDEPKPAL++AF+LS+RQA+DILEIRLRQLARLETIKIQQELAELR+EK+T Sbjct: 421 DKVIKIIRESDEPKPALMDAFRLSERQADDILEIRLRQLARLETIKIQQELAELRSEKST 480 Query: 480 LQDLLDNPASMKRLVIKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQKGW 539 LQDLLDNP+SMKRLVIKEIEAD+KQFGD RRT+IE AEKAV+E +VIDEPVTV+ISQKGW Sbjct: 481 LQDLLDNPSSMKRLVIKEIEADEKQFGDKRRTLIEVAEKAVVETRVIDEPVTVVISQKGW 540 Query: 540 VRARGGHGHDATQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVP 599 VRAR GHGHDA QFTFKA D LY FECRTVD LL FGSNGRIY+V V +LP ARGDGVP Sbjct: 541 VRARTGHGHDAAQFTFKASDALYDTFECRTVDTLLVFGSNGRIYSVAVAALPGARGDGVP 600 Query: 600 ITTLVDLGNGNNLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDL 659 ITTLV+L +G +LHYFAGP D +LLAS AGYGFTAK GDM+SR + GKAFITLDEGD Sbjct: 601 ITTLVELASGTRVLHYFAGPADVTLLLASTAGYGFTAKSGDMVSRTRSGKAFITLDEGDE 660 Query: 660 PLAPRPMPAGASAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQ 719 PL PRP+ AGASAIACLS +GR+LVFG+DEIK+L +GGRGVILM+LEKNEKLLAAQ I+Q Sbjct: 661 PLTPRPIFAGASAIACLSEKGRVLVFGIDEIKSLTAGGRGVILMDLEKNEKLLAAQPISQ 720 Query: 720 KGVLVSGTGRGGKAQDVTLSAVALALHIGKRARKGKALESKLKATALAAV 769 +GV+VSG GRG KAQ++ LSA LA+HIGKRARKGK LESK+KAT L V Sbjct: 721 RGVVVSGIGRGAKAQEILLSASGLAVHIGKRARKGKGLESKIKATTLTPV 770 >F1W2E6.1 F1W2E6_9BURK Topoisomerase IV subunit A Length = 772 Score = 1263 bits (3267), Expect = 0.0, Method: Compositional matrix adjust. Identities = 616/773 (79%), Positives = 689/773 (89%), Gaps = 4/773 (0%) Query: 1 MTEQANLFE--QPAPPDG-ESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRIL 57 MTEQA LF+ P PPDG E+LTL+TFAERAYLDYAISVVKGRALPDV+DGQKPVQRRIL Sbjct: 1 MTEQATLFDGDTPEPPDGAETLTLATFAERAYLDYAISVVKGRALPDVSDGQKPVQRRIL 60 Query: 58 YAMNELGLNATAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNF 117 +AMN+LGLNA AKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQ FSLRYPLIDGQGNF Sbjct: 61 FAMNQLGLNAAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQGFSLRYPLIDGQGNF 120 Query: 118 GSRDGDGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLN 177 GSRDGDGAAAMRYTEARLTPIS LLLDEID+GTVDFQPNYDGSTEEP LLP RLPF+LLN Sbjct: 121 GSRDGDGAAAMRYTEARLTPISSLLLDEIDLGTVDFQPNYDGSTEEPSLLPGRLPFVLLN 180 Query: 178 GASGIAVGMATEIPSHNLREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPST 237 GASGIAVGMATEIPSHNLREVA+AAVA+IRNP +THAELM I GPDFP GGQIIT + Sbjct: 181 GASGIAVGMATEIPSHNLREVAQAAVALIRNPALTHAELMAIIPGPDFPSGGQIITSAAA 240 Query: 238 IAEIYQSGRGSLKVRARWKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGK 297 ++E+Y +GRGSLKVRA WKIE+MARGQWQAV+TELP G S+QKVLEEIEELTNPKIKLGK Sbjct: 241 LSEMYANGRGSLKVRALWKIEEMARGQWQAVVTELPHGTSAQKVLEEIEELTNPKIKLGK 300 Query: 298 KTLTPEQQAQKQSILAMLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETS 357 K L+P+Q AQKQ +L++LDAVRDESGREAPVRLVFEPKSKNQDQTEF N LLAQTSLETS Sbjct: 301 KALSPDQLAQKQLMLSLLDAVRDESGREAPVRLVFEPKSKNQDQTEFTNMLLAQTSLETS 360 Query: 358 SSINLVMIGGDGRPRQKGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILL 417 +SINLVMIGGDGRPRQKGL DIL EWIAFRF T+TRRS F+L+KVEDRIHILEGRE ILL Sbjct: 361 ASINLVMIGGDGRPRQKGLGDILREWIAFRFDTVTRRSHFRLKKVEDRIHILEGRETILL 420 Query: 418 NIDKVIRIIRESDEPKPALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEK 477 NID+VIRIIRESDEPKPAL+ AFKLSDRQAEDILEIRLRQLARLE IKIQQELA LR EK Sbjct: 421 NIDEVIRIIRESDEPKPALMGAFKLSDRQAEDILEIRLRQLARLEAIKIQQELAGLRTEK 480 Query: 478 ATLQDLLDNPASMKRLVIKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQK 537 +TL++LL+NP +MK+L+IKEI+AD+K+FGDARRT+IE AE+A +EQKVIDEPVTV+ISQK Sbjct: 481 STLEELLNNPGAMKKLIIKEIDADEKRFGDARRTLIEAAERATVEQKVIDEPVTVVISQK 540 Query: 538 GWVRARGGHGHDATQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDG 597 GW+RAR GHGHD QF FKAGD LY FECRT+D+LL FGSNGRIY++ V+SLP ARGDG Sbjct: 541 GWLRARTGHGHDPAQFAFKAGDDLYRTFECRTLDSLLAFGSNGRIYSIAVSSLPGARGDG 600 Query: 598 VPITTLVDLGNGNNLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEG 657 PI+ LV+L +G+ +LHYFAG D+ MLLAS AGYGF A+ DM+ R K GKAFITLD G Sbjct: 601 APISALVELASGSTVLHYFAGSADSTMLLASTAGYGFIARAADMIGRNKAGKAFITLDAG 660 Query: 658 DLPLAPRPMPAGASAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAI 717 DLPL P+ + AS++ACLSG+GRLLVFGLDE+KT+ SGGRG+ILM LE EKLLAAQ + Sbjct: 661 DLPLPPQMLIPSASSVACLSGEGRLLVFGLDELKTM-SGGRGMILMALEDGEKLLAAQPV 719 Query: 718 TQKGVLVSGTGRGGKAQDVTLSAVALALHIGKRARKGKALESKLKATALAAVA 770 +Q+GVLVSG GRGGK Q+V+LSA LALH GKRARKGKALESKLK L A++ Sbjct: 720 SQRGVLVSGIGRGGKTQEVSLSATGLALHTGKRARKGKALESKLKPHTLTAIS 772 >E1TC50.1 E1TC50_BURSG DNA topoisomerase IV, A subunit EC=5.99.1.3 Length = 774 Score = 1129 bits (2921), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/757 (71%), Positives = 639/757 (84%) Query: 6 NLFEQPAPPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYAMNELGL 65 +LF +P P+G+ LTL +AE AYL YA+SVVKGRALPDV DGQKPVQRRILYAMNELGL Sbjct: 8 DLFTEPPAPEGDFLTLGNYAEGAYLQYAVSVVKGRALPDVCDGQKPVQRRILYAMNELGL 67 Query: 66 NATAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGSRDGDGA 125 + AKP KSA VVGDV+GK HPHGDQS YDALVR+AQDF++RYPLIDGQGNFGSRDGDGA Sbjct: 68 SDNAKPVKSARVVGDVIGKYHPHGDQSAYDALVRLAQDFAMRYPLIDGQGNFGSRDGDGA 127 Query: 126 AAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPARLPFLLLNGASGIAVG 185 AAMRYTEARLTPISKLLLDEID GTVDF PNYDG EEP+ LPARLPFLLLNGASGIAVG Sbjct: 128 AAMRYTEARLTPISKLLLDEIDQGTVDFMPNYDGVEEEPRQLPARLPFLLLNGASGIAVG 187 Query: 186 MATEIPSHNLREVARAAVAMIRNPKITHAELMTHITGPDFPGGGQIITPPSTIAEIYQSG 245 +ATEIPSHNLREVA A VAMIRNPKI HAELM H+ GPDFPGGGQII+ + IA Y++G Sbjct: 188 LATEIPSHNLREVAAATVAMIRNPKIAHAELMQHLPGPDFPGGGQIISSEAEIAAAYETG 247 Query: 246 RGSLKVRARWKIEDMARGQWQAVITELPPGVSSQKVLEEIEELTNPKIKLGKKTLTPEQQ 305 RGSLKVRARWKIED+ARGQWQ VITELPP ++QKVLEEIEE TNPKIKLGKK LTPEQ Sbjct: 248 RGSLKVRARWKIEDLARGQWQLVITELPPNTAAQKVLEEIEEQTNPKIKLGKKALTPEQL 307 Query: 306 AQKQSILAMLDAVRDESGREAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSSSINLVMI 365 KQ++L +LDAVRDESG++APVRLVFEPKS DQTEF+NTLLA TSLE+++S+NLVM+ Sbjct: 308 QAKQTMLGLLDAVRDESGKDAPVRLVFEPKSSRIDQTEFVNTLLAHTSLESNASLNLVMV 367 Query: 366 GGDGRPRQKGLADILGEWIAFRFVTITRRSQFKLQKVEDRIHILEGREAILLNIDKVIRI 425 GGDGRPRQKGL++IL EWIAFRF T+TRR++ +L KV+DRIHILEGR + LNID+VIRI Sbjct: 368 GGDGRPRQKGLSEILHEWIAFRFATVTRRTRHRLTKVDDRIHILEGRMIVYLNIDEVIRI 427 Query: 426 IRESDEPKPALIEAFKLSDRQAEDILEIRLRQLARLETIKIQQELAELRNEKATLQDLLD 485 IRESDEPK AL+ AF LSDRQA+DILEIRLRQLARLE IKI++ELAELR+EKA L++LL Sbjct: 428 IRESDEPKVALMAAFGLSDRQADDILEIRLRQLARLEKIKIEKELAELRDEKAKLEELLG 487 Query: 486 NPASMKRLVIKEIEADDKQFGDARRTVIEEAEKAVLEQKVIDEPVTVIISQKGWVRARGG 545 + ++MKRL+IKEIEAD KQ+GD RRT+I++ ++A E +VIDEPVTV++SQKGWVRA G Sbjct: 488 SESAMKRLLIKEIEADAKQYGDERRTLIQQEKRATYEARVIDEPVTVVVSQKGWVRALKG 547 Query: 546 HGHDATQFTFKAGDGLYGAFECRTVDNLLGFGSNGRIYTVGVNSLPNARGDGVPITTLVD 605 HG D FTFKAGDGLY AF+CRT D L+ +GSNGR+Y+V V SLP RGDGVP+T+L++ Sbjct: 548 HGLDTAGFTFKAGDGLYAAFQCRTPDTLVAWGSNGRVYSVAVASLPGGRGDGVPVTSLIE 607 Query: 606 LGNGNNLLHYFAGPVDTQMLLASDAGYGFTAKVGDMLSRVKGGKAFITLDEGDLPLAPRP 665 L +G++L+HY+A D +LLAS G+GF AKVGDM+SRVK GK+F+T+D G +PLAP P Sbjct: 608 LESGSHLMHYYAASADQALLLASSNGFGFIAKVGDMVSRVKAGKSFMTIDAGAVPLAPMP 667 Query: 666 MPAGASAIACLSGQGRLLVFGLDEIKTLASGGRGVILMELEKNEKLLAAQAITQKGVLVS 725 + AS +ACLS GRLLVFG+DE+KTL+ GGRGV LM L+ E L+ A AI GV++ Sbjct: 668 LLPDASQVACLSSTGRLLVFGIDEMKTLSGGGRGVTLMALDDKETLVQALAINGAGVMLI 727 Query: 726 GTGRGGKAQDVTLSAVALALHIGKRARKGKALESKLK 762 G RGG+ + LS ALA H+GKRARKG+A ESKLK Sbjct: 728 GARRGGRLDEEKLSGAALAAHVGKRARKGRAPESKLK 764