BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0182.p (765 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B7WRG9.1 B7WRG9_COMTE Diguanylate cyclase/phosphodiesterase 922 0.0 D6V332.1 D6V332_9BRAD Diguanylate cyclase/phosphodiesterase with... 776 0.0 B8INP3.1 B8INP3_METNO Diguanylate cyclase/phosphodiesterase with... 750 0.0 B7KRN5.1 B7KRN5_METC4 Diguanylate cyclase/phosphodiesterase with... 731 0.0 Q98G38.1 Q98G38_RHILO Mlr3504 protein 713 0.0 >B7WRG9.1 B7WRG9_COMTE Diguanylate cyclase/phosphodiesterase Length = 820 Score = 922 bits (2382), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/739 (63%), Positives = 552/739 (74%), Gaps = 2/739 (0%) Query: 1 VAGIATGFGIWATHFIAMLAYSPGIQSGYNIALTLLSLIAAIVLTIASFAAASSPNLKYG 60 VAGIATGFGIWAT+FIAML YSP IQ+ YN L L+SL AAI+L I SFA S + G Sbjct: 40 VAGIATGFGIWATYFIAMLTYSPRIQNSYNTTLVLVSLSAAILLAILSFAVTSGLPQRLG 99 Query: 61 RWLGGALAGGGIAVMHYTGMAAFEIAGRILWNMPLVAASVILGASFGAISLPVGLRAKTY 120 R GG L G GIA+MHY+GMAAFE+ GRILWN ++ S++LG+ F +LP LR KT+ Sbjct: 100 REKGGLLVGCGIAIMHYSGMAAFEVPGRILWNPSMMVISIVLGSLFSTFALPTELRKKTH 159 Query: 121 TSISMGALLLTLAICSHHFTAMAAAVLVLDPGVSVSPNAIPTSWLAIMVTIASFTIFLLT 180 +I+ GALLLTL IC+HHF AMA A L+ D ++VS NA P WLAI VTIA IFLLT Sbjct: 160 RTITSGALLLTLVICNHHFAAMATADLIQDQSITVSTNATPVYWLAITVTIACLLIFLLT 219 Query: 181 FAGFALDIRERRQAQLAIDRLNSLANAAFEGLLVCEDNVITTANISLANLAGCSVDQLVG 240 F L++ A ++ LNSLANAAFEGLLV ED VIT AN SLA LAGCS ++L Sbjct: 220 LIVFTLNVWNLHLATREMEHLNSLANAAFEGLLVYEDGVITMANTSLAKLAGCSAEELTH 279 Query: 241 ANLMSILPDPGAARNCLGSTSSIAFETMLQPVAGA-PFAVEAFSRPVIYGNRQKIVVAIR 299 +L I PD ARN L IA +TML P++G VEA SR VIY + + +VAIR Sbjct: 280 RDLSLIFPD-AMARNWLEEKPCIALKTMLHPLSGEDSIVVEATSRSVIYARKLQKIVAIR 338 Query: 300 DLRDRKKAEKDIYFLAHHDTLTGLSNRNAFNQRLQQLLEEHAPGGQHEDKCMAVLCLDLD 359 DLRD KAE+DI++L +HDTLTGL NR AFNQ L++LL++H G+ K +AVLCLDLD Sbjct: 339 DLRDHIKAERDIHYLFNHDTLTGLINRKAFNQELEKLLQDHGANGRLCGKHLAVLCLDLD 398 Query: 360 RFKEVNDLFGHAAGDKLLQTVAYTAKLVLRQGQMMARLGGDEFAIIAPGLGDPKQAGRIA 419 RFKEVNDLFGHAAGD LLQTVA A+ LR Q+MARLGGDEFAIIAPGL DP+QA RIA Sbjct: 399 RFKEVNDLFGHAAGDGLLQTVARRAQQTLRSDQLMARLGGDEFAIIAPGLSDPQQAERIA 458 Query: 420 QELINAFKAENQRVSTSSAMISASIGIAVFPNDAGDDTSLMSCADTALYRAKSDGRGVYR 479 Q+L + F N+ STS A IS +IGIA+FP + S+M CA AL +AK+DGRGVYR Sbjct: 459 QKLFSVFADANRSASTSCATISINIGIAIFPQHGHNSPSIMRCAAKALCQAKADGRGVYR 518 Query: 480 FFEEAMGEQVRDRRKIEHDLRFAITRNELSLVYQPLAQIIGREVLGFEALLRWQHPERGN 539 FF+ + +Q+RDR+++EHDLR AI ELSLVYQPL Q REV+GFE LLRW+H +RG Sbjct: 519 FFDVTLDQQMRDRQRLEHDLRLAIANQELSLVYQPLVQTKSREVVGFETLLRWKHQKRGL 578 Query: 540 VPPGVFIPIAEECNLILHIGEWVLREACQQAATWNNPLSLSVNVSAAQLHSPGFVQSVGD 599 VPP VFIPIAEEC IL IGEWVL +AC++A++W L+++VNVSA QLHSP FVQ + Sbjct: 579 VPPSVFIPIAEECGQILQIGEWVLHQACKEASSWKRHLNIAVNVSAVQLHSPQFVQITRE 638 Query: 600 ILAQTGLHASRLELEITETALIRDPGRALTMLRQLKELGVRIAMDDFGTGYSSLSNLRAF 659 IL QT L SRLELEITETALIRDP AL+ +RQLKE+GVRIAMDDFGTGYSSLS+L F Sbjct: 639 ILKQTKLPPSRLELEITETALIRDPDIALSTIRQLKEIGVRIAMDDFGTGYSSLSHLLTF 698 Query: 660 PFDKIKIDQSFIKSVNVNKQAAAIVRAVLGLGRGLELPVIAEGVETEEELAFLRAESCQE 719 PFDKIKID SFIKSV+VN +AA IVRAVL LGRGLELPV+AEGVETEEELAFL AESC+E Sbjct: 699 PFDKIKIDGSFIKSVHVNPRAATIVRAVLELGRGLELPVLAEGVETEEELAFLSAESCEE 758 Query: 720 AQGYLLGPPQSIGVFRHLT 738 QGYL G P+SI + LT Sbjct: 759 VQGYLFGKPESIERYLQLT 777 >D6V332.1 D6V332_9BRAD Diguanylate cyclase/phosphodiesterase with PAS/PAC and MHYT sensor(S) Length = 798 Score = 776 bits (2005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/744 (56%), Positives = 518/744 (69%), Gaps = 8/744 (1%) Query: 1 VAGIATGFGIWATHFIAMLAYSPGIQSGYNIALTLLSLIAAIVLTIASFAAASSPNLKYG 60 V+ +A GFGIW+THFIAMLA+SPGI SGYNIALT +SL+ A++LT A P G Sbjct: 52 VSAVAIGFGIWSTHFIAMLAFSPGIPSGYNIALTAISLVVAMLLTGGGLVVAMIPGWSAG 111 Query: 61 RWLGGALAGGGIAVMHYTGMAAFEIAGRILWNMPLVAASVILGASFGAISLPVGLRAKTY 120 LGGA+ GGIA MHYTGMAAFEIAG ++W+ +VA S++LGA+ GAI+LPVGL ++ Sbjct: 112 PALGGAIVAGGIAAMHYTGMAAFEIAGIVVWDFGMVAWSIVLGATLGAIALPVGLHDQSE 171 Query: 121 TSISMGALLLTLAICSHHFTAMAAAVLVLDPGVSVSPNAIPTSWLAIMVTIASFTIFLLT 180 + GA LLTLAICSHHFT MAA ++ DP ++V A+P + LAI+V AS TI LL+ Sbjct: 172 KWKAAGAALLTLAICSHHFTGMAAVTILPDPNIAVPATALPPALLAILVCAASLTIILLS 231 Query: 181 FAGFALDIRERRQAQLAIDRLNSLANAAFEGLLVCEDNVITTANISLANLAGCSVDQLVG 240 ALD+R+RR+A+L DR+ LANAA EGL+VC+ + I T N S A L G S VG Sbjct: 232 LTAVALDVRDRRRAELETDRMRGLANAAVEGLVVCDGDTIVTVNESFAQLVGLSSAMPVG 291 Query: 241 ANLMSILPDPGAARNCLGSTSSIAFETMLQPVAGAPFAVEAFSRPVIYGNRQKIVVAIRD 300 L LPD AR L ++S+ E L+ G+ E RP+ Y R VVA+RD Sbjct: 292 NKLDLCLPD-DTARERLLTSSNQPMEVTLRHHDGSMIPAEVILRPIDYAGRPHHVVAVRD 350 Query: 301 LRDRKKAEKDIYFLAHHDTLTGLSNRNAFNQRLQQLLEEHAPGGQHEDKCMAVLCLDLDR 360 LR RKK E+ I +LAHHD LT L NR +FN + + L +D +AVLCLDLDR Sbjct: 351 LRARKKNEQHIRYLAHHDALTSLPNRTSFNAAIDEAL-----AALPKDNKLAVLCLDLDR 405 Query: 361 FKEVNDLFGHAAGDKLLQTVAYTAKLVLRQGQMMARLGGDEFAIIAPGLGDPKQAGRIAQ 420 FKEVNDLFGHAAGD++LQTVA +L GQ+M+RLGGDEFAI+ P + A R A+ Sbjct: 406 FKEVNDLFGHAAGDRVLQTVANRIGGLLGSGQIMSRLGGDEFAILLPNIARADAARRFAE 465 Query: 421 ELINAFKAENQRVSTSSAMISASIGIAVFPNDAGDDTSLMSCADTALYRAKSDGRGVYRF 480 ++ A + + T IS+S+GIA++P+DA D L+S ADTALYRAK++GR YRF Sbjct: 466 NVLAALRLKGDTPETDG--ISSSLGIALYPDDANDRQMLLSHADTALYRAKTEGRNTYRF 523 Query: 481 FEEAMGEQVRDRRKIEHDLRFAITRNELSLVYQPLAQIIGREVLGFEALLRWQHPERGNV 540 FE MG +VR+RR IEHDLR A+ RNEL LVYQP I V GFEALLRW+HP RG+V Sbjct: 524 FEAKMGAEVRERRMIEHDLRHAVARNELRLVYQPQHDIQNNIVTGFEALLRWKHPTRGDV 583 Query: 541 PPGVFIPIAEECNLILHIGEWVLREACQQAATWNNPLSLSVNVSAAQLHSPGFVQSVGDI 600 P FIPIAEE IL IGEWVLR AC++AA+W PL+++VNVS Q++ P F V I Sbjct: 584 SPATFIPIAEEAGAILGIGEWVLRTACREAASWPQPLTIAVNVSTLQIYDPNFAHLVHRI 643 Query: 601 LAQTGLHASRLELEITETALIRDPGRALTMLRQLKELGVRIAMDDFGTGYSSLSNLRAFP 660 L +TGL +RLELEITETAL+RD RAL LRQ+K LGV IAMDDFGTGYSSLSNLRAFP Sbjct: 644 LIETGLSPNRLELEITETALVRDLNRALLTLRQIKALGVHIAMDDFGTGYSSLSNLRAFP 703 Query: 661 FDKIKIDQSFIKSVNVNKQAAAIVRAVLGLGRGLELPVIAEGVETEEELAFLRAESCQEA 720 FDKIKID SFIKSV+ N+QAA IVR VLGLGRGL LPV+AEGVET E+ FLR ++C E Sbjct: 704 FDKIKIDGSFIKSVDSNEQAATIVRTVLGLGRGLGLPVLAEGVETAGEMKFLREQNCDEI 763 Query: 721 QGYLLGPPQSIGVFRHLTHLAEAP 744 QGYL+G P +I FRH TH P Sbjct: 764 QGYLIGRPAAIENFRHFTHNEAVP 787 >B8INP3.1 B8INP3_METNO Diguanylate cyclase/phosphodiesterase with PAS/PAC and MHYT sensor(S) Length = 794 Score = 750 bits (1936), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/739 (57%), Positives = 515/739 (69%), Gaps = 9/739 (1%) Query: 1 VAGIATGFGIWATHFIAMLAYSPGIQSGYNIALTLLSLIAAIVLTIASFAAASSPNLKYG 60 VA +A G GIWATHFIAMLA+ PG+ SGY+I LT+ SL A+VLT A + + Sbjct: 52 VAAVAGGSGIWATHFIAMLAFEPGLPSGYDIGLTVRSLAYAVVLTGLGLAVTLLRRIPFT 111 Query: 61 RWLGGALAGGGIAVMHYTGMAAFEIAGRILWNMPLVAASVILGASFGAISLPVGLRAKTY 120 LGG + G GIA MHYTGMAAFEIAGRI+W+ LVAAS++LGA G +LPV L Sbjct: 112 AGLGGLILGSGIAAMHYTGMAAFEIAGRIIWDPTLVAASLVLGALLGGAALPVALGPHGV 171 Query: 121 TSISMGALLLTLAICSHHFTAMAAAVLVLDPGVSVSPNAIPTSWLAIMVTIASFTIFLLT 180 S + GALLL AICS HF AM A +V DP +++S A+P+ WLA+ V +AS I LL Sbjct: 172 RSQTAGALLLLGAICSLHFIAMGALTIVPDPSIAISETAVPSRWLAVAVALASGAILLLA 231 Query: 181 FAGFALDIRERRQAQLAIDRLNSLANAAFEGLLVCEDNVITTANISLANLAGCSVDQLVG 240 ALDIR+RR + +RL SLANAA EGL+VC D++I +AN S L G + + Sbjct: 232 GGALALDIRDRRTI-VESERLRSLANAAVEGLVVCRDDIIVSANDSFGRLVGIAATAVAE 290 Query: 241 ANLMSILPDPGAARNCLGSTSSIAFETMLQPVAGAPFAVEAFSRPVIYGNRQKIVVAIRD 300 ++L LPDP A R L S ET L+ G VE RPV YG R VA+RD Sbjct: 291 SSLSRFLPDP-ATRLALTRQSEQLIETELRGAEGEMIPVEVIMRPVTYGRRPHFAVAVRD 349 Query: 301 LRDRKKAEKDIYFLAHHDTLTGLSNRNAFNQRLQQLLEEHAPGGQHEDKCMAVLCLDLDR 360 LR R++AE I FLAHHD LTGL+NR +F QRL L+ G+ +AVLCLDLDR Sbjct: 350 LRARRQAEGRIQFLAHHDALTGLANRTSFTQRLDLELKLAEATGRK----LAVLCLDLDR 405 Query: 361 FKEVNDLFGHAAGDKLLQTVAYTAKLVLRQGQMMARLGGDEFAIIAPGLGDPKQAGRIAQ 420 FKEVNDLFGHAAGD +L VA +L + QMMARLGGDEFA++A AG +A+ Sbjct: 406 FKEVNDLFGHAAGDAMLVNVARVVTGILGETQMMARLGGDEFAVLA-ACDHAITAGHLAE 464 Query: 421 ELINAFKAENQRVSTSSAMISASIGIAVFPNDAGDDTSLMSCADTALYRAKSDGRGVYRF 480 ++ A ++EN + +++ SIGIA++P+DA + L+S ADTALYRAKS+GRG YRF Sbjct: 465 RILEALRSEN--ADAAGPLVATSIGIALYPDDASERDVLLSHADTALYRAKSEGRGTYRF 522 Query: 481 FEEAMGEQVRDRRKIEHDLRFAITRNELSLVYQPLAQIIGREVLGFEALLRWQHPERGNV 540 FE MG QVRDRR +EH+LR A+ R E+ LVYQP Q+ EV+GFE LLRW HPERG V Sbjct: 523 FEHKMGVQVRDRRILEHELRHAVARGEMHLVYQPQTQVETGEVIGFEVLLRWHHPERGAV 582 Query: 541 PPGVFIPIAEECNLILHIGEWVLREACQQAATWNNPLSLSVNVSAAQLHSPGFVQSVGDI 600 P VFIPIAEE IL IGEWVLR+AC+ AA+W NPL+++VNVSA Q+H+P FVQ V ++ Sbjct: 583 SPAVFIPIAEESGAILQIGEWVLRQACRDAASWPNPLAVAVNVSAVQIHAPHFVQLVHEV 642 Query: 601 LAQTGLHASRLELEITETALIRDPGRALTMLRQLKELGVRIAMDDFGTGYSSLSNLRAFP 660 L QTGL RLE+EITETALIRDP RAL+ LRQ+K LGV IAMDDFGTGYSSLSNLR+FP Sbjct: 643 LLQTGLKPDRLEIEITETALIRDPVRALSTLRQVKALGVHIAMDDFGTGYSSLSNLRSFP 702 Query: 661 FDKIKIDQSFIKSVNVNKQAAAIVRAVLGLGRGLELPVIAEGVETEEELAFLRAESCQEA 720 FDKIKID SFI++V+ N+Q AAIVR+VLGLGRGL LPV+AEGVET+ EL FL AE+C A Sbjct: 703 FDKIKIDPSFIRAVDTNEQTAAIVRSVLGLGRGLGLPVLAEGVETDAELRFLAAENCDAA 762 Query: 721 QGYLLGPPQSIGVFRHLTH 739 QGYL+G P I F TH Sbjct: 763 QGYLMGRPAPIERFSQFTH 781 >B7KRN5.1 B7KRN5_METC4 Diguanylate cyclase/phosphodiesterase with PAS/PAC and MHYT sensor(S) Length = 795 Score = 731 bits (1888), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/746 (55%), Positives = 517/746 (69%), Gaps = 8/746 (1%) Query: 1 VAGIATGFGIWATHFIAMLAYSPGIQSGYNIALTLLSLIAAIVLTIASFAAASSPNLKYG 60 VA A G GIWATHFIAMLA++PG+ SGY++ALT LSL+ ++ + + A K Sbjct: 52 VAATAGGSGIWATHFIAMLAFAPGVPSGYDVALTGLSLVISVAFAGSGLSLAVLVGGKVA 111 Query: 61 RWLGGALAGGGIAVMHYTGMAAFEIAGRILWNMPLVAASVILGASFGAISLPVGLRAKTY 120 W+GGA+ G GIA MHYTGMAA+++AG W+ V S+ LG G +L + A+ Sbjct: 112 AWVGGAVLGFGIAAMHYTGMAAYDVAGHKAWDPATVGVSLALGGLLGGAALAAQVGARGL 171 Query: 121 TSISMGALLLTLAICSHHFTAMAAAVLVLDPGVSVSPNAIPTSWLAIMVTIASFTIFLLT 180 ALLL LAICSHHFTAM A + DP V+VS +A+P +WLA+ V +ASF I LL Sbjct: 172 GRQLPTALLLLLAICSHHFTAMGAVTVTPDPAVAVSESAVPNAWLAVAVALASFAILLLA 231 Query: 181 FAGFALDIRERRQAQLAIDRLNSLANAAFEGLLVCEDNVITTANISLANLAGCSVDQLVG 240 A ALD R+RR A+L DRL+SLANAA EGL+VC + I +AN S A L G L G Sbjct: 232 GAALALDARDRRHAKLEADRLHSLANAAVEGLVVCTGDTIVSANRSFAKLVGLPQAALAG 291 Query: 241 ANLMSILPDPGAARNCLGSTSSIAFETMLQPVAGAPFAVEAFSRPVIYGNRQKIVVAIRD 300 L + LP A R L S E L+ G VE +PV + R VAIRD Sbjct: 292 TALSAYLPG-DATRLALASQPERPVEAELRQADGTLVPVEVIMQPVEHAGRPHYAVAIRD 350 Query: 301 LRDRKKAEKDIYFLAHHDTLTGLSNRNAFNQRLQQLLEEHAPGGQHEDKCMAVLCLDLDR 360 L+ R++AE I FLAHHD LTGL+NR +F++RL Q + GG+ +AVLCLDLDR Sbjct: 351 LQARRQAESQIQFLAHHDALTGLANRTSFSKRLDQEMRAADVGGRK----LAVLCLDLDR 406 Query: 361 FKEVNDLFGHAAGDKLLQTVAYTAKLVLRQGQMMARLGGDEFAIIAPGLGDPKQAGRIAQ 420 FKEVNDLFGHAAGD +L++VA+ L QMMARLGGDEFA++ P G P +AGR+A+ Sbjct: 407 FKEVNDLFGHAAGDAMLESVAHIVSAELDDSQMMARLGGDEFAVLMPCAG-PSEAGRLAE 465 Query: 421 ELINAFKAENQRVSTSSAMISASIGIAVFPNDAGDDTSLMSCADTALYRAKSDGRGVYRF 480 ++ A + + RV I+ SIG+A++P+DA + +L+S ADTALYRAKS+GRG YRF Sbjct: 466 RILEALR--SGRVEAGGPQIATSIGVALYPDDARERAALLSNADTALYRAKSEGRGTYRF 523 Query: 481 FEEAMGEQVRDRRKIEHDLRFAITRNELSLVYQPLAQIIGREVLGFEALLRWQHPERGNV 540 FE MG +VR+RR +EHDLR A+ R E+ LVYQP + V+GFEALLRW+HPERG V Sbjct: 524 FEAKMGTEVRERRLLEHDLRHAVARGEMHLVYQPQTDVSLGAVIGFEALLRWKHPERGYV 583 Query: 541 PPGVFIPIAEECNLILHIGEWVLREACQQAATWNNPLSLSVNVSAAQLHSPGFVQSVGDI 600 P VFIPIAEE + IL IGEWVLREAC++AA+W NPLS++VNVSA Q+HSP FV V ++ Sbjct: 584 SPAVFIPIAEESDAILQIGEWVLREACREAASWPNPLSIAVNVSAVQIHSPHFVGLVHEV 643 Query: 601 LAQTGLHASRLELEITETALIRDPGRALTMLRQLKELGVRIAMDDFGTGYSSLSNLRAFP 660 L +TGL RLE+E+TETALI DP RAL LRQLK LG+RIAMDDFGTGYSSLSNLR+FP Sbjct: 644 LLRTGLAPDRLEVEVTETALINDPNRALLTLRQLKALGLRIAMDDFGTGYSSLSNLRSFP 703 Query: 661 FDKIKIDQSFIKSVNVNKQAAAIVRAVLGLGRGLELPVIAEGVETEEELAFLRAESCQEA 720 FDKIKIDQSF++SV+ N+Q AAIVR+VLGLGRGL LPV+AEGVET+ EL+FL AE C A Sbjct: 704 FDKIKIDQSFVRSVDSNEQTAAIVRSVLGLGRGLGLPVLAEGVETDAELSFLVAEQCHAA 763 Query: 721 QGYLLGPPQSIGVFRHLTHLAEAPSP 746 QGYL+G P I F TH P+P Sbjct: 764 QGYLMGRPSPIDRFTQHTHGTARPNP 789 >Q98G38.1 Q98G38_RHILO Mlr3504 protein Length = 808 Score = 713 bits (1840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/746 (53%), Positives = 512/746 (68%), Gaps = 16/746 (2%) Query: 1 VAGIATGFGIWATHFIAMLAYSPGIQSGYNIALTLLSLIAAIVLTIASFAAASSPNLKYG 60 +A +TGFGIWATHFIAMLA++PGI S Y+ L++LSL A++ LT A A+ + Sbjct: 44 IAATSTGFGIWATHFIAMLAFTPGIPSAYDPWLSVLSLAASVALTAAGMWIATLRDEFEH 103 Query: 61 RWLGGALAGGGIAVMHYTGMAAFEIAGRILWNMPLVAASVILGASFGAISLPVGLRAKTY 120 +GGA+ GGGIA MHYTGMAAFE+ GRI WN+ +VA S++ G + GA++L V LR + Sbjct: 104 HLVGGAVLGGGIAAMHYTGMAAFEVQGRIEWNLLMVAVSLLAGVTLGALALHVVLRRPSL 163 Query: 121 TSISMGALLLTLAICSHHFTAMAAAVLVLDPGVSVSPNAIPTSWLAIMVTIASFTIFLLT 180 T+ S+GA+LLTLAIC+ HF M A + D +++S I + A A+ I +L+ Sbjct: 164 TATSVGAVLLTLAICTLHFIGMGAVSIFPDSSIAISEYTIEPTSQAFAAAAATLVILVLS 223 Query: 181 FAGFALDIRERRQAQLAIDRLNSLANAAFEGLLVCEDNVITTANISLANLAGCSVDQLVG 240 + +D+R RRQ +L +DR++ LANAA EGL+VC+ N I +AN S+ L G L G Sbjct: 224 ASALWIDLRFRRQ-KLEVDRMHGLANAAVEGLIVCDGNRIVSANDSMGKLTGTLAATLNG 282 Query: 241 ANLMSILPDPGAARNCLGSTSSIAFETMLQPVAGAPFAVEAFSRPVIYGNRQKIVVAIRD 300 L + + A N S + +E L+ G VE +R + Y + V+A+RD Sbjct: 283 TELRELFDEHTA--NDAASLAGQPWEAELRNRDGTRIPVELIARSIDYCGKPHNVIAVRD 340 Query: 301 LRDRKKAEKDIYFLAHHDTLTGLSNRNAFNQRLQQLLE--------EHAPGGQHEDKCMA 352 +R+RKKAE++I LAH D LTGL+NR +F+ RL + + G+H +A Sbjct: 341 IRERKKAEEEILRLAHFDPLTGLANRRSFSSRLDMEIASMNRIANGDTGVKGRH----LA 396 Query: 353 VLCLDLDRFKEVNDLFGHAAGDKLLQTVAYTAKLVLRQGQMMARLGGDEFAIIAPGLGDP 412 +L DLDRFKEVNDL+GH AGD +LQ VA A VLR GQM+ARLGGDEFAIIAP L DP Sbjct: 397 LLLFDLDRFKEVNDLYGHGAGDAMLQKVATCAAGVLRHGQMLARLGGDEFAIIAPNLPDP 456 Query: 413 KQAGRIAQELINAFKAENQRVSTSSAMISASIGIAVFPNDAGDDTSLMSCADTALYRAKS 472 + AGRIA L+ A + EN RV+ ++SASIGIA++P DA D T L+S ADTALYRAK+ Sbjct: 457 QAAGRIAGSLLAAMREEN-RVAAGGGLVSASIGIAIYPLDAEDQTGLISHADTALYRAKT 515 Query: 473 DGRGVYRFFEEAMGEQVRDRRKIEHDLRFAITRNELSLVYQPLAQIIGREVLGFEALLRW 532 +GR YR+FE +MG + RD+R +EH+LR A+ R E LVYQP +I ++GFEAL+RW Sbjct: 516 EGRDTYRYFEASMGAEARDKRIMEHELRQAVVRGEFYLVYQPQKEISSGRMVGFEALIRW 575 Query: 533 QHPERGNVPPGVFIPIAEECNLILHIGEWVLREACQQAATWNNPLSLSVNVSAAQLHSPG 592 +HPERG+V P FIP+AEE I IG+WVL AC++AA W NPL+++VNVSA QLH+P Sbjct: 576 RHPERGDVSPATFIPVAEESGAIGQIGDWVLDAACEEAARWKNPLTVAVNVSAVQLHNPN 635 Query: 593 FVQSVGDILAQTGLHASRLELEITETALIRDPGRALTMLRQLKELGVRIAMDDFGTGYSS 652 F + V + L +TGL +RLELEITETAL++D RAL LRQ+K LGVR+AMDDFGTGYSS Sbjct: 636 FSRKVHETLLRTGLAPTRLELEITETALVKDMPRALATLRQVKSLGVRVAMDDFGTGYSS 695 Query: 653 LSNLRAFPFDKIKIDQSFIKSVNVNKQAAAIVRAVLGLGRGLELPVIAEGVETEEELAFL 712 LSNLRAFPFDKIKID SFIK+V+ N Q AAIVRAVLGLGRGL LPV+AEGVET EL FL Sbjct: 696 LSNLRAFPFDKIKIDASFIKAVDTNGQVAAIVRAVLGLGRGLGLPVLAEGVETLGELKFL 755 Query: 713 RAESCQEAQGYLLGPPQSIGVFRHLT 738 AE+C+ QGY LG P I F LT Sbjct: 756 DAEACEIGQGYYLGKPAPIEAFDDLT 781