BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0177.p (361 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISA5.1 D8ISA5_HERSS Beta-N-acetylhexosaminidase protein EC=3.2... 513 e-143 A4G6R3.1 A4G6R3_HERAR Beta-hexosaminidase (N-acetyl-beta-glucosa... 511 e-143 A6SXR8.1 A6SXR8_JANMA Beta-N-acetylhexosaminidase EC=3.2.1.52 509 e-142 B5LAX6.1 B5LAX6_9BURK N-acetylhexosaminidase EC=3.2.1.52 493 e-137 B5WGY8.1 B5WGY8_9BURK Beta-N-acetylhexosaminidase EC=3.2.1.52 450 e-124 >D8ISA5.1 D8ISA5_HERSS Beta-N-acetylhexosaminidase protein EC=3.2.1.52 Length = 342 Score = 513 bits (1321), Expect = e-143, Method: Compositional matrix adjust. Identities = 249/316 (78%), Positives = 273/316 (86%) Query: 15 QSRQPLGPVMLDVVGTTLTAEDIRRIQHPLTGGVILFARNYENRQQLVTLTQGIHAARPG 74 Q+ +PLGPVMLDVVGT L A DI R+QHPLTGGVILFARNYE+R QLV LT I ARPG Sbjct: 3 QAVKPLGPVMLDVVGTRLEAADIARLQHPLTGGVILFARNYESRAQLVALTSAIRQARPG 62 Query: 75 VLIAVDHEGGRVQRFRTDGFTHLPAMRTLGELWDRDVLQATKVTTAAGYVLASELRACGV 134 +LIAVDHEGGRVQRFRTDGFT LPAM LG+LWDRDVLQATKV TA G+VLA+ELRACG+ Sbjct: 63 ILIAVDHEGGRVQRFRTDGFTRLPAMGQLGQLWDRDVLQATKVATATGFVLAAELRACGI 122 Query: 135 DLSFTPVLDLDFGGSSVIGTRSFHRDPRVVTLLAKSLNHGLALAGMANCGKHFPGHGYVT 194 DLSFTPVLDLD+G S+VIG RSFHRDPRVVTL+AKSLNHGLALAGMANCGKHFPGHG+VT Sbjct: 123 DLSFTPVLDLDYGASTVIGDRSFHRDPRVVTLMAKSLNHGLALAGMANCGKHFPGHGFVT 182 Query: 195 ADSHVDLPVDERPLKDILGDDAAPYDWLGMSLTAVMPAHVIYPKVDKHPAGFSKKWLGIL 254 ADSHV +PVDER L +ILGDDA PYDWLGMSL AVMPAHVIYPKVD PAGFSK WL +L Sbjct: 183 ADSHVAIPVDERELDEILGDDATPYDWLGMSLAAVMPAHVIYPKVDAQPAGFSKVWLSML 242 Query: 255 RKDLGFQGVIFSDDLSMHGASVAGGALDGANAALRAGCDMVLMCNSPDKADQLLSGLRTK 314 R+ GFQGVIFSDDLSMHGASVAGG L+ A AAL AGCD+ L+CNSPDKAD +L+GL+ Sbjct: 243 RERFGFQGVIFSDDLSMHGASVAGGPLEAAQAALDAGCDVALICNSPDKADAILAGLQGG 302 Query: 315 VSPASAARIAALVPQG 330 ASAAR A L+P G Sbjct: 303 TDAASAARRATLLPCG 318 >A4G6R3.1 A4G6R3_HERAR Beta-hexosaminidase (N-acetyl-beta-glucosaminidase) (Beta-N-acetylhexosaminidase) EC=3.2.1.52 Length = 357 Score = 511 bits (1315), Expect = e-143, Method: Compositional matrix adjust. Identities = 244/313 (77%), Positives = 271/313 (86%), Gaps = 3/313 (0%) Query: 20 LGPVMLDVVGTTLTAEDIRRIQHPLTGGVILFARNYENRQQLVTLTQGIHAARPGVLIAV 79 GPVMLDVVGT L+A+DIRRIQHPLTGGVILFARNY+NR QL LT IH AR G++IAV Sbjct: 17 FGPVMLDVVGTELSADDIRRIQHPLTGGVILFARNYKNRAQLTELTAAIHGARAGIVIAV 76 Query: 80 DHEGGRVQRFRTDGFTHLPAMRTLGELWDRDVLQATKVTTAAGYVLASELRACGVDLSFT 139 DHEGGRVQRF+TDGFTHLPAMR LGELWD+DVL ATK T GYVLA+ELRACGVDLSFT Sbjct: 77 DHEGGRVQRFKTDGFTHLPAMRKLGELWDKDVLAATKAATEVGYVLAAELRACGVDLSFT 136 Query: 140 PVLDLDFGGSSVIGTRSFHRDPRVVTLLAKSLNHGLALAGMANCGKHFPGHGYVTADSHV 199 PVLDLD+G S VIG R+FHRD RVV+LLAKSLNHGL LAGM NCGKHFPGHG+V ADSH+ Sbjct: 137 PVLDLDYGASGVIGDRAFHRDARVVSLLAKSLNHGLMLAGMLNCGKHFPGHGFVKADSHL 196 Query: 200 DLPVDERPLKDILGDDAAPYDWLGMSLTAVMPAHVIYPKVDKHPAGFSKKWLGILRKDLG 259 ++PVDER LKDIL +DAAPY +LG+SL VMPAHVIYPKVDKHPAGFS+KWL +LRKD G Sbjct: 197 EIPVDERELKDILAEDAAPYKYLGLSLAGVMPAHVIYPKVDKHPAGFSRKWLTMLRKDFG 256 Query: 260 FQGVIFSDDLSMHGASVAGGALDGANAALRAGCDMVLMCNSPDKADQLLSGLRTKVSPA- 318 F G+IFSDDLSM GASVAG +DG +AAL AGCDM+L+CNSPDKADQLL+GL+ K S A Sbjct: 257 FDGLIFSDDLSMEGASVAGNVVDGGHAALAAGCDMILICNSPDKADQLLAGLKIKDSKAM 316 Query: 319 --SAARIAALVPQ 329 SAARIAAL PQ Sbjct: 317 TQSAARIAALTPQ 329 >A6SXR8.1 A6SXR8_JANMA Beta-N-acetylhexosaminidase EC=3.2.1.52 Length = 350 Score = 509 bits (1311), Expect = e-142, Method: Compositional matrix adjust. Identities = 245/313 (78%), Positives = 271/313 (86%), Gaps = 3/313 (0%) Query: 20 LGPVMLDVVGTTLTAEDIRRIQHPLTGGVILFARNYENRQQLVTLTQGIHAARPGVLIAV 79 GPVMLDVVGTTL+A+DIRRIQHPLTGGVILFARNY +R QL LT IHAARPG++IAV Sbjct: 10 FGPVMLDVVGTTLSADDIRRIQHPLTGGVILFARNYTDRAQLTALTAAIHAARPGIVIAV 69 Query: 80 DHEGGRVQRFRTDGFTHLPAMRTLGELWDRDVLQATKVTTAAGYVLASELRACGVDLSFT 139 DHEGGRVQRF+TDGFTHLPAMR LG LWD+DVL ATK T GYVLA+ELRACGVDLSFT Sbjct: 70 DHEGGRVQRFKTDGFTHLPAMRKLGALWDKDVLAATKAATDVGYVLAAELRACGVDLSFT 129 Query: 140 PVLDLDFGGSSVIGTRSFHRDPRVVTLLAKSLNHGLALAGMANCGKHFPGHGYVTADSHV 199 PVLDLD+G S VIG R+FHRD RVVT+LAKSLNHGL LAGM NCGKHFPGHG+V ADSH+ Sbjct: 130 PVLDLDYGESGVIGDRAFHRDARVVTMLAKSLNHGLMLAGMLNCGKHFPGHGFVKADSHL 189 Query: 200 DLPVDERPLKDILGDDAAPYDWLGMSLTAVMPAHVIYPKVDKHPAGFSKKWLGILRKDLG 259 ++PVDER LK IL DAAPYDWLG+SL VMPAHVIYPKVDKHPAGFS+KWL +LRKD G Sbjct: 190 EIPVDERELKQILAADAAPYDWLGLSLAGVMPAHVIYPKVDKHPAGFSRKWLTMLRKDFG 249 Query: 260 FQGVIFSDDLSMHGASVAGGALDGANAALRAGCDMVLMCNSPDKADQLLSGLR---TKVS 316 F G+IFSDDLSM GASVAG +DGA+AAL+AGCDMVL+CNSPDKADQLL+GL+ K + Sbjct: 250 FDGLIFSDDLSMEGASVAGTVIDGAHAALQAGCDMVLICNSPDKADQLLAGLQVRDNKAT 309 Query: 317 PASAARIAALVPQ 329 SA RIAAL PQ Sbjct: 310 QESAVRIAALTPQ 322 >B5LAX6.1 B5LAX6_9BURK N-acetylhexosaminidase EC=3.2.1.52 Length = 349 Score = 493 bits (1270), Expect = e-137, Method: Compositional matrix adjust. Identities = 239/311 (76%), Positives = 263/311 (84%), Gaps = 1/311 (0%) Query: 20 LGPVMLDVVGTTLTAEDIRRIQHPLTGGVILFARNYENRQQLVTLTQGIHAARPGVLIAV 79 LGPVMLDVVG +L+A+DIRRI+HPLTGGVILF RNY++R QL LT IHAARPG+LIAV Sbjct: 13 LGPVMLDVVGASLSADDIRRIRHPLTGGVILFTRNYQDRAQLTALTAAIHAARPGILIAV 72 Query: 80 DHEGGRVQRFRTDGFTHLPAMRTLGELWDRDVLQATKVTTAAGYVLASELRACGVDLSFT 139 DHEGGRVQRFRTDGFT LPAMR LG+ WDRDVL A + TA G+VLASELRACGVDLSFT Sbjct: 73 DHEGGRVQRFRTDGFTRLPAMRLLGQQWDRDVLGAVETATALGFVLASELRACGVDLSFT 132 Query: 140 PVLDLDFGGSSVIGTRSFHRDPRVVTLLAKSLNHGLALAGMANCGKHFPGHGYVTADSHV 199 PVLDLD+G SSVIG R+FHRDPRVV LLAKSLNHGLALAGMANCGKHFPGHGYV DSH Sbjct: 133 PVLDLDYGDSSVIGERAFHRDPRVVALLAKSLNHGLALAGMANCGKHFPGHGYVHGDSHS 192 Query: 200 DLPVDERPLKDILGDDAAPYDWLGMSLTAVMPAHVIYPKVDKHPAGFSKKWLGILRKDLG 259 LP+D+R L I+ +D PYDWLGMSL AVMPAHVIY KVDKH AGFSKKWL ILR+++G Sbjct: 193 SLPIDDRSLAQIMEEDVKPYDWLGMSLAAVMPAHVIYSKVDKHSAGFSKKWLTILREEIG 252 Query: 260 FQGVIFSDDLSMHGASVAGGALDGANAALRAGCDMVLMCNSPDKADQLLSGLR-TKVSPA 318 F GVIFSDDLSM A AGG LDGA AAL AGCD+VL+CNSPDKADQLL+GL S A Sbjct: 253 FNGVIFSDDLSMEAAGSAGGVLDGAKAALAAGCDVVLICNSPDKADQLLAGLDAVDSSAA 312 Query: 319 SAARIAALVPQ 329 +AR+A LVPQ Sbjct: 313 FSARLATLVPQ 323 >B5WGY8.1 B5WGY8_9BURK Beta-N-acetylhexosaminidase EC=3.2.1.52 Length = 342 Score = 450 bits (1158), Expect = e-124, Method: Compositional matrix adjust. Identities = 224/346 (64%), Positives = 264/346 (76%), Gaps = 14/346 (4%) Query: 21 GPVMLDVVGTTLTAEDIRRIQHPLTGGVILFARNYENRQQLVTLTQGIHAARPGVLIAVD 80 GPVMLDVVG TL +D RR+ HP+TGGVILFAR++E+R QLV LT I A RP +LIAVD Sbjct: 6 GPVMLDVVGKTLNHDDKRRLAHPMTGGVILFARHFESRAQLVALTDAIRAIRPDLLIAVD 65 Query: 81 HEGGRVQRFRTDGFTHLPAMRTLGELWDRDVLQATKVTTAAGYVLASELRACGVDLSFTP 140 HEGGRVQRFRTDGFT LP+M LG LWD DVL ATKVTTA GY+LA+ELRACG+D+SFTP Sbjct: 66 HEGGRVQRFRTDGFTVLPSMGKLGALWDHDVLHATKVTTAVGYILAAELRACGIDMSFTP 125 Query: 141 VLDLDFGGSSVIGTRSFHRDPRVVTLLAKSLNHGLALAGMANCGKHFPGHGYVTADSHVD 200 VLDLD+G S VIG R+FHRDPRVV LLAKSLNHGLALAGM+NCGKHFPGHG+ ADSHV Sbjct: 126 VLDLDYGHSQVIGDRAFHRDPRVVALLAKSLNHGLALAGMSNCGKHFPGHGFAQADSHVA 185 Query: 201 LPVDERPLKDILGDDAAPYDWLGMSLTAVMPAHVIYPKVDKHPAGFSKKWL-GILRKDLG 259 +PVDERPL +ILG+D APYDWLG+SL AV+PAHV+YP+VD+ PAGFS+ WL ILR LG Sbjct: 186 MPVDERPLDEILGNDVAPYDWLGLSLGAVLPAHVVYPRVDEKPAGFSRIWLQDILRGKLG 245 Query: 260 FQGVIFSDDLSMHGASVAGGALDGANAALRAGCDMVLMCNSPDKADQLLSGLRTKVSPAS 319 F+G IFSDDLSM A G + A+AAL+AGCDMVL+CN PD+A+++L LR S S Sbjct: 246 FEGAIFSDDLSMEAARQGGTLTEAASAALQAGCDMVLICNQPDEAEKVLDALRVTPSQES 305 Query: 320 AARIAALVPQGXRRGAGMGCAATGW----ALPRGEKAAAVARMIFS 361 R+ + P+G A W A PR +A + R F+ Sbjct: 306 RQRLERMRPRGE---------ALAWSKLMAEPRYAEAQKLVRGAFA 342