BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0141.p (609 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IS76.1 D8IS76_HERSS Putative uncharacterized protein 1056 0.0 A6SX51.1 A6SX51_JANMA Uncharacterized conserved protein 839 0.0 A4G3W8.1 A4G3W8_HERAR Putative uncharacterized protein 827 0.0 C6XD96.1 C6XD96_METSD Diguanylate cyclase/phosphodiesterase 692 0.0 E4QP16.1 E4QP16_METS6 Diguanylate cyclase/phosphodiesterase 692 0.0 >D8IS76.1 D8IS76_HERSS Putative uncharacterized protein Length = 600 Score = 1056 bits (2732), Expect = 0.0, Method: Compositional matrix adjust. Identities = 496/595 (83%), Positives = 549/595 (92%), Gaps = 2/595 (0%) Query: 15 ESQLLSHLHEIIAQRSLTALFQPIIRMRSGEIVGYEGLIRGPSNSPLHSPLNLFKVARAX 74 E +LS LHEIIAQR LTALFQPI+RMR+GEI+GYEGLIRGPSN+PLHSPL LFKVARA Sbjct: 5 EDPMLSLLHEIIAQRKLTALFQPIVRMRNGEILGYEGLIRGPSNTPLHSPLALFKVARA- 63 Query: 75 PNKLSVQVEHLCRHIVMAQFAQSGLPGNLFLNVSPGALVQPEAIQGETLRHLEKLGINPQ 134 + +SVQ+E+LCRHIV+ +FAQ GLPGNLFLNVSPGAL+QPEAIQGETLR+L+ LG+NPQ Sbjct: 64 -HNMSVQMEYLCRHIVLTRFAQLGLPGNLFLNVSPGALMQPEAIQGETLRYLDTLGVNPQ 122 Query: 135 RIIIELTENEPTYDYTLLRNAAMHYRNMGFQIAIDDLGEGFSSLRLWSELQPEYVKVDMH 194 RIIIELTENEPTYDY LRNAAMHYR+MGFQIAIDDLGEGFSSLRLWSELQPEYVKVDMH Sbjct: 123 RIIIELTENEPTYDYAQLRNAAMHYRDMGFQIAIDDLGEGFSSLRLWSELQPEYVKVDMH 182 Query: 195 FIQGINNDPMKLQFVRSIQEIAEKSGSIVIAEGIETQAELLTIRDLGIACGQGYHIARPH 254 F+QGIN+DPMKLQFVRSIQEIAEKSGSIVIAEGIE+QAELLTIRDLGIACGQGYHI+RP Sbjct: 183 FVQGINHDPMKLQFVRSIQEIAEKSGSIVIAEGIESQAELLTIRDLGIACGQGYHISRPL 242 Query: 255 ANPKTVVGDDISKVLRRDKVPLAAQKYGPGKKSTTVFKLLRESLYVAPDVSNDKVYNLFV 314 P + DD++K LRRDKVPL A+KYGPGK STTVFKLLRE+ YV+P+VSND VY++FV Sbjct: 243 PEPPVSISDDVTKTLRRDKVPLDAKKYGPGKHSTTVFKLLRETRYVSPEVSNDTVYDMFV 302 Query: 315 NDPQLQALPVVSNGIPVGLINRYSMVERFARLYGRELYGKKSCTFFMDPNPLLTEQDTSL 374 NDPQLQALPVVSNG+P+GLINRYSMVERFARLYGRELYGKKSC FFMDPNP+LTEQ TSL Sbjct: 303 NDPQLQALPVVSNGLPIGLINRYSMVERFARLYGRELYGKKSCAFFMDPNPILTEQSTSL 362 Query: 375 QDLSHILVQAESHHLSNGFIIVDQGQYVGMGTGHDLLREITQMQIEAARYANPLTQLPGN 434 QDLS++LV AESHHLSNGFII D+GQY+G+GTGHDLLREITQMQI+AAR+ANPLTQLPGN Sbjct: 363 QDLSNLLVHAESHHLSNGFIITDRGQYMGLGTGHDLLREITQMQIDAARHANPLTQLPGN 422 Query: 435 VPINEHIEFLLQSGVEFCICYCDLDNFKPFNDVYGYRKGDDMIQLTGRTLSQFCDTQLDF 494 VPIN+HIE+LLQSGVEFCICYCDLD FKPFNDVYGYRKGDDMIQ TGR L Q CD +LDF Sbjct: 423 VPINDHIEYLLQSGVEFCICYCDLDQFKPFNDVYGYRKGDDMIQATGRVLQQACDPELDF 482 Query: 495 IGHIGGDDFLIMFQSEDWEHRCKAMLEAFAVASQSFYYVEDKERGGYYSEDRQGNRVLHP 554 IGHIGGDDFLI+FQSEDWE RC++ML+ F ++ FYY ED ERGGYY+EDRQGNRV H Sbjct: 483 IGHIGGDDFLILFQSEDWEKRCRSMLDNFDAETRGFYYDEDVERGGYYTEDRQGNRVFHK 542 Query: 555 LVSLSLGAVKIEPSQYSSPHQIASAATKAKKQAKKTPGNSLFIERRVPATFSWAM 609 LVS+SLGAVKIEPSQYSSPHQIASAAT+AKKQAKK PGNSLFIERR+PATFSWA+ Sbjct: 543 LVSVSLGAVKIEPSQYSSPHQIASAATRAKKQAKKIPGNSLFIERRIPATFSWAL 597 >A6SX51.1 A6SX51_JANMA Uncharacterized conserved protein Length = 658 Score = 839 bits (2168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/591 (66%), Positives = 476/591 (80%), Gaps = 2/591 (0%) Query: 11 SEQQESQLLSHLHEIIAQRSLTALFQPIIRMRSGEIVGYEGLIRGPSNSPLHSPLNLFKV 70 ++ E L+ L E+I R LT LFQPIIRM+SGEI+GYEGLIRGPS+SPLHSPLNLFKV Sbjct: 52 TDPAEDHLVQRLKEVIEHRQLTPLFQPIIRMQSGEIIGYEGLIRGPSDSPLHSPLNLFKV 111 Query: 71 ARAXPNKLSVQVEHLCRHIVMAQFAQSGLPGNLFLNVSPGALVQPEAIQGETLRHLEKLG 130 AR+ LSV+VEHLCR I + +FA+ LPG LFLNVSP L+QP+ GETL ++ ++G Sbjct: 112 ARSC--NLSVEVEHLCRRITLEKFAELRLPGKLFLNVSPECLIQPDVKHGETLGYIHEVG 169 Query: 131 INPQRIIIELTENEPTYDYTLLRNAAMHYRNMGFQIAIDDLGEGFSSLRLWSELQPEYVK 190 INP+R+IIELTE++PTYDY LLR A HYR MGF+IAIDDLGEGFSSLRLWSEL+PEYVK Sbjct: 170 INPERVIIELTESQPTYDYDLLREAVTHYRAMGFRIAIDDLGEGFSSLRLWSELRPEYVK 229 Query: 191 VDMHFIQGINNDPMKLQFVRSIQEIAEKSGSIVIAEGIETQAELLTIRDLGIACGQGYHI 250 +DMHF+QGIN DP+KLQFVRSIQEIAEKSG+IVIAEGIET AELL IRDLG+A GQGY I Sbjct: 230 IDMHFVQGINLDPIKLQFVRSIQEIAEKSGTIVIAEGIETDAELLMIRDLGVAYGQGYKI 289 Query: 251 ARPHANPKTVVGDDISKVLRRDKVPLAAQKYGPGKKSTTVFKLLRESLYVAPDVSNDKVY 310 ARPHANP T + D+ +LR + V + + G G K T KLLR VAP+V N+++Y Sbjct: 290 ARPHANPATTLSTDLCNLLRHNGVAVYPHENGRGHKMLTAMKLLRSVKAVAPEVHNNRIY 349 Query: 311 NLFVNDPQLQALPVVSNGIPVGLINRYSMVERFARLYGRELYGKKSCTFFMDPNPLLTEQ 370 +F NDP L+ +PVVSNGIPVGLI R ++++RFAR Y REL+GKKSCT FMD NPL+T++ Sbjct: 350 EMFNNDPTLEVIPVVSNGIPVGLITRANLIDRFARPYLRELHGKKSCTLFMDSNPLITDK 409 Query: 371 DTSLQDLSHILVQAESHHLSNGFIIVDQGQYVGMGTGHDLLREITQMQIEAARYANPLTQ 430 +T+L LS I+V A+ HHL NGFII D GQY+GMG HDL+REITQMQI AARYANPLT Sbjct: 410 NTALHALSQIIVDADRHHLFNGFIITDNGQYMGMGNAHDLMREITQMQINAARYANPLTL 469 Query: 431 LPGNVPINEHIEFLLQSGVEFCICYCDLDNFKPFNDVYGYRKGDDMIQLTGRTLSQFCDT 490 LPGNVPI+EHI+ LL++G FC CY DLD+FKP+NDVYGYRKGDDM++LTG+ LS CD Sbjct: 470 LPGNVPIDEHIDRLLENGTRFCACYVDLDHFKPYNDVYGYRKGDDMLRLTGKILSGHCDP 529 Query: 491 QLDFIGHIGGDDFLIMFQSEDWEHRCKAMLEAFAVASQSFYYVEDKERGGYYSEDRQGNR 550 Q DF+GHIGGDDF+I+FQSEDWE RC+A+++AF A FY VED+++GGY SEDR+G + Sbjct: 530 QKDFVGHIGGDDFIILFQSEDWEQRCRAIIDAFVAAVPDFYCVEDRKKGGYISEDRRGKQ 589 Query: 551 VLHPLVSLSLGAVKIEPSQYSSPHQIASAATKAKKQAKKTPGNSLFIERRV 601 V H L ++SLG VK+EP Y S HQIA+A AKKQAKK PGNSLFI+RR+ Sbjct: 590 VFHTLATISLGLVKVEPGHYGSHHQIATATADAKKQAKKIPGNSLFIDRRL 640 >A4G3W8.1 A4G3W8_HERAR Putative uncharacterized protein Length = 611 Score = 827 bits (2137), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/583 (66%), Positives = 474/583 (81%), Gaps = 2/583 (0%) Query: 18 LLSHLHEIIAQRSLTALFQPIIRMRSGEIVGYEGLIRGPSNSPLHSPLNLFKVARAXPNK 77 L L EII R LT LFQPIIRM+SGEI+GYEGLIRGPS+SPLHSPLNLFKVAR+ Sbjct: 12 LAQRLREIILHRQLTPLFQPIIRMQSGEIIGYEGLIRGPSDSPLHSPLNLFKVARSC--N 69 Query: 78 LSVQVEHLCRHIVMAQFAQSGLPGNLFLNVSPGALVQPEAIQGETLRHLEKLGINPQRII 137 LSV+VEHLCR I + +FA+ LPG LFLNVSP LVQP+ GETL ++ ++GINP+R+I Sbjct: 70 LSVEVEHLCRRITLEKFAELQLPGRLFLNVSPECLVQPDVRHGETLGYIHEVGINPERVI 129 Query: 138 IELTENEPTYDYTLLRNAAMHYRNMGFQIAIDDLGEGFSSLRLWSELQPEYVKVDMHFIQ 197 IELTE+ PTYDY LLR A HYR MGF+IAIDDLGEGFSSLRLWSEL+PEYVK+DMHF+Q Sbjct: 130 IELTESHPTYDYELLREAVTHYRAMGFRIAIDDLGEGFSSLRLWSELRPEYVKIDMHFVQ 189 Query: 198 GINNDPMKLQFVRSIQEIAEKSGSIVIAEGIETQAELLTIRDLGIACGQGYHIARPHANP 257 GIN+DP+KLQFVRSIQEIAEKSG+IVIAEGIET AELL IRDLG++ GQGY IARPHA+P Sbjct: 190 GINHDPIKLQFVRSIQEIAEKSGTIVIAEGIETDAELLMIRDLGVSYGQGYKIARPHAHP 249 Query: 258 KTVVGDDISKVLRRDKVPLAAQKYGPGKKSTTVFKLLRESLYVAPDVSNDKVYNLFVNDP 317 T + D+ +LR + V + + G G K T KLLR V+P+V N+++Y +F +DP Sbjct: 250 ATALSADLRNLLRHNGVAVYPHEAGRGHKILTALKLLRSVQSVSPEVHNNRIYEMFNSDP 309 Query: 318 QLQALPVVSNGIPVGLINRYSMVERFARLYGRELYGKKSCTFFMDPNPLLTEQDTSLQDL 377 L+ +PVVSNG+PVGLI R ++++RFAR Y REL+GKKSCT FMD NPL+T+++T+L L Sbjct: 310 TLEVIPVVSNGLPVGLITRANLIDRFARPYLRELHGKKSCTLFMDSNPLITDKNTALHAL 369 Query: 378 SHILVQAESHHLSNGFIIVDQGQYVGMGTGHDLLREITQMQIEAARYANPLTQLPGNVPI 437 S I+V A+ HHL NGFII D GQY+GMG HDL+REITQMQI AARYANPLT LPGNVPI Sbjct: 370 SQIIVDADRHHLFNGFIITDAGQYMGMGNAHDLMREITQMQISAARYANPLTLLPGNVPI 429 Query: 438 NEHIEFLLQSGVEFCICYCDLDNFKPFNDVYGYRKGDDMIQLTGRTLSQFCDTQLDFIGH 497 +EHI+ LL++G FC CY DLD+FKP+NDVYGYRKGDD++++TG+ LS CD Q DF+GH Sbjct: 430 DEHIDRLLENGTRFCACYVDLDHFKPYNDVYGYRKGDDILRVTGKILSGHCDPQRDFVGH 489 Query: 498 IGGDDFLIMFQSEDWEHRCKAMLEAFAVASQSFYYVEDKERGGYYSEDRQGNRVLHPLVS 557 IGGDDF+I+FQSEDWE RC+A+L+AFA A+ FY ED+ RGGY SEDR+G +V H LVS Sbjct: 490 IGGDDFIILFQSEDWEQRCRAILDAFASAAPDFYSEEDRLRGGYVSEDRRGEKVFHTLVS 549 Query: 558 LSLGAVKIEPSQYSSPHQIASAATKAKKQAKKTPGNSLFIERR 600 +SLG VK+EP QY S H+IA+A +AK+QAKK PGNSLFI+RR Sbjct: 550 ISLGLVKVEPGQYLSHHKIATATAEAKQQAKKIPGNSLFIDRR 592 >C6XD96.1 C6XD96_METSD Diguanylate cyclase/phosphodiesterase Length = 619 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/599 (55%), Positives = 441/599 (73%), Gaps = 3/599 (0%) Query: 3 EPDNAQPASEQQESQLLS-HLHEIIAQRSLTALFQPIIRMRSGEIVGYEGLIRGPSNSPL 61 +P A A+ Q E+ + S LH+I+ R LTA+FQPI +RS I G+EGLIRGP+++ L Sbjct: 21 QPALAVRAAAQDETAISSLELHKILKHRQLTAVFQPIADLRSASIFGHEGLIRGPADTRL 80 Query: 62 HSPLNLFKVARAXPNKLSVQVEHLCRHIVMAQFAQSGLPGNLFLNVSPGALVQPEAIQGE 121 H PL LF+ A + L ++VEHL R +V+ FAQ G LFLNVSP +L+QP +G Sbjct: 81 HMPLALFE--EAEQHHLLLEVEHLSRQVVLESFAQQGANAKLFLNVSPASLLQPHVARGA 138 Query: 122 TLRHLEKLGINPQRIIIELTENEPTYDYTLLRNAAMHYRNMGFQIAIDDLGEGFSSLRLW 181 TL ++ +LG++P +IIELTEN PT+DY LR+AA HYR+MGF+IA+DDLGEGFSSLRLW Sbjct: 139 TLSYIHQLGLDPHDVIIELTENSPTFDYDTLRHAAEHYRSMGFEIAMDDLGEGFSSLRLW 198 Query: 182 SELQPEYVKVDMHFIQGINNDPMKLQFVRSIQEIAEKSGSIVIAEGIETQAELLTIRDLG 241 SEL+P+YVK+D HFI+ I+ D +KL FVRSIQ+IA SG+ VIAEGIET+AEL+ ++DL Sbjct: 199 SELRPDYVKIDKHFIRNIDRDQVKLDFVRSIQQIALNSGTKVIAEGIETEAELMIVKDLK 258 Query: 242 IACGQGYHIARPHANPKTVVGDDISKVLRRDKVPLAAQKYGPGKKSTTVFKLLRESLYVA 301 I GQGY I RP A+ T + +++++R+ V + P + + + KL+R V+ Sbjct: 259 IPYGQGYLINRPQASLHTALSPVAAELMQRNAVHVYQSAAVPVQARSNISKLIRYVSPVS 318 Query: 302 PDVSNDKVYNLFVNDPQLQALPVVSNGIPVGLINRYSMVERFARLYGRELYGKKSCTFFM 361 P SND VY +F P L +LPVV+ G PVGLI+RY+M++ AR Y RELYGK+ C+ FM Sbjct: 319 PQTSNDDVYQIFEKQPSLYSLPVVAQGRPVGLISRYNMIDHLARPYTRELYGKRYCSIFM 378 Query: 362 DPNPLLTEQDTSLQDLSHILVQAESHHLSNGFIIVDQGQYVGMGTGHDLLREITQMQIEA 421 D PL+ + SLQ LS +++ E HHLSNGFII + G Y+GMG+GHDLLREITQMQI A Sbjct: 379 DNQPLVVDNSLSLQALSDLIINMEPHHLSNGFIITESGNYLGMGSGHDLLREITQMQINA 438 Query: 422 ARYANPLTQLPGNVPINEHIEFLLQSGVEFCICYCDLDNFKPFNDVYGYRKGDDMIQLTG 481 ARYANPLT LPGNVPINEH++ LLQ+G+ F CYCDLD+FKPFNDVYG+R+GD++IQ TG Sbjct: 439 ARYANPLTMLPGNVPINEHMDRLLQAGITFHACYCDLDSFKPFNDVYGFRRGDELIQYTG 498 Query: 482 RTLSQFCDTQLDFIGHIGGDDFLIMFQSEDWEHRCKAMLEAFAVASQSFYYVEDKERGGY 541 + L++ +LDF+GH+GGDDF+++FQSEDWE RC +L A A +FY D++RGG Sbjct: 499 KLLNEQIANELDFVGHVGGDDFILIFQSEDWEERCLRVLNILAQAIPAFYDEADRQRGGI 558 Query: 542 YSEDRQGNRVLHPLVSLSLGAVKIEPSQYSSPHQIASAATKAKKQAKKTPGNSLFIERR 600 +EDRQGN + +P VS+S+G+VK +P + S H++A+A T AKKQAKK GNSLF+ERR Sbjct: 559 AAEDRQGNPLFYPFVSMSVGSVKADPVGFRSHHEVAAAMTIAKKQAKKISGNSLFLERR 617 >E4QP16.1 E4QP16_METS6 Diguanylate cyclase/phosphodiesterase Length = 619 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/599 (55%), Positives = 441/599 (73%), Gaps = 3/599 (0%) Query: 3 EPDNAQPASEQQESQLLS-HLHEIIAQRSLTALFQPIIRMRSGEIVGYEGLIRGPSNSPL 61 +P A A+ Q E+ + S LH+I+ R LTA+FQPI +RS I G+EGLIRGP+++ L Sbjct: 21 QPALAVRAAAQDETAISSLELHKILKHRQLTAVFQPIADLRSASIFGHEGLIRGPADTRL 80 Query: 62 HSPLNLFKVARAXPNKLSVQVEHLCRHIVMAQFAQSGLPGNLFLNVSPGALVQPEAIQGE 121 H PL LF+ A + L ++VEHL R +V+ FAQ G LFLNVSP +L+QP +G Sbjct: 81 HMPLALFE--EAEQHHLLLEVEHLSRQVVLESFAQQGANVKLFLNVSPASLLQPHVARGA 138 Query: 122 TLRHLEKLGINPQRIIIELTENEPTYDYTLLRNAAMHYRNMGFQIAIDDLGEGFSSLRLW 181 TL ++ +LG++P +IIELTEN PT+DY LR+AA HYR+MGF+IA+DDLGEGFSSLRLW Sbjct: 139 TLSYIHQLGLDPHDVIIELTENSPTFDYDTLRHAAEHYRSMGFEIAMDDLGEGFSSLRLW 198 Query: 182 SELQPEYVKVDMHFIQGINNDPMKLQFVRSIQEIAEKSGSIVIAEGIETQAELLTIRDLG 241 SEL+P+YVK+D HFI+ I+ D +KL FVRSIQ+IA SG+ VIAEGIET+AEL+ ++DL Sbjct: 199 SELRPDYVKIDKHFIRNIDRDQVKLDFVRSIQQIALNSGTKVIAEGIETEAELMIVKDLK 258 Query: 242 IACGQGYHIARPHANPKTVVGDDISKVLRRDKVPLAAQKYGPGKKSTTVFKLLRESLYVA 301 I GQGY I RP A+ T + +++++R+ V + P + + + KL+R V+ Sbjct: 259 IPYGQGYLINRPQASLHTALSPVAAELMQRNAVHVYQSAAVPVQARSNISKLIRYVSPVS 318 Query: 302 PDVSNDKVYNLFVNDPQLQALPVVSNGIPVGLINRYSMVERFARLYGRELYGKKSCTFFM 361 P SND VY +F P L +LPVV+ G PVGLI+RY+M++ AR Y RELYGK+ C+ FM Sbjct: 319 PQTSNDDVYQIFEKQPSLYSLPVVAQGRPVGLISRYNMIDHLARPYTRELYGKRYCSIFM 378 Query: 362 DPNPLLTEQDTSLQDLSHILVQAESHHLSNGFIIVDQGQYVGMGTGHDLLREITQMQIEA 421 D PL+ + SLQ LS +++ E HHLSNGFII + G Y+GMG+GHDLLREITQMQI A Sbjct: 379 DNQPLIVDNSLSLQALSDLIINMEPHHLSNGFIITESGNYLGMGSGHDLLREITQMQINA 438 Query: 422 ARYANPLTQLPGNVPINEHIEFLLQSGVEFCICYCDLDNFKPFNDVYGYRKGDDMIQLTG 481 ARYANPLT LPGNVPINEH++ LLQ+G+ F CYCDLD+FKPFNDVYG+R+GD++IQ TG Sbjct: 439 ARYANPLTMLPGNVPINEHMDRLLQAGITFHACYCDLDSFKPFNDVYGFRRGDELIQYTG 498 Query: 482 RTLSQFCDTQLDFIGHIGGDDFLIMFQSEDWEHRCKAMLEAFAVASQSFYYVEDKERGGY 541 + L++ +LDF+GH+GGDDF+++FQSEDWE RC +L A A +FY D++RGG Sbjct: 499 KLLNEQIANELDFVGHVGGDDFILIFQSEDWEERCLHVLNTLAQAIPAFYDEADRQRGGI 558 Query: 542 YSEDRQGNRVLHPLVSLSLGAVKIEPSQYSSPHQIASAATKAKKQAKKTPGNSLFIERR 600 +EDRQGN + +P VS+S+G+VK +P + S H++A+A T AKKQAKK GNSLF+ERR Sbjct: 559 AAEDRQGNPLFYPFVSMSVGSVKADPVGFRSHHEVAAAMTIAKKQAKKISGNSLFLERR 617