BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0089.p (472 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3XBX9.1 C3XBX9_OXAFO Pyruvate kinase EC=2.7.1.40 674 0.0 C3X5Q6.1 C3X5Q6_OXAFO Pyruvate kinase EC=2.7.1.40 672 0.0 C6BH48.1 C6BH48_RALP1 Pyruvate kinase EC=2.7.1.40 667 0.0 Q1LHQ2.1 Q1LHQ2_RALME Pyruvate kinase EC=2.7.1.40 666 0.0 E2SXG6.1 E2SXG6_9RALS Pyruvate kinase EC=2.7.1.40 666 0.0 >C3XBX9.1 C3XBX9_OXAFO Pyruvate kinase EC=2.7.1.40 Length = 473 Score = 674 bits (1739), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/456 (70%), Positives = 384/456 (84%), Gaps = 1/456 (0%) Query: 1 MRRQRQAKIVATLGPASATKDMIKALFEAGADVFRFNFSHGTHADHHARFEIVRAVEREV 60 MRRQR+AK+VATLGPAS+TK+MI +LFEAG D+FRFNFSHGT DH AR E VR VER V Sbjct: 1 MRRQRKAKVVATLGPASSTKEMILSLFEAGVDMFRFNFSHGTQDDHRARHEAVREVERLV 60 Query: 61 GRPIAILADLQGPKLRVGQFAEGKVQLEAGQEFVLDRDTTPGDNTRVCLPHAELFEVIAA 120 GRPIAILADLQGPKLR+G+FAEGKV L+ G EF+ DR+T GD RV LPH ELF V++A Sbjct: 61 GRPIAILADLQGPKLRIGKFAEGKVNLKTGDEFIFDRNTADGDEKRVNLPHPELFGVMSA 120 Query: 121 GQSLLLDDGKLRLKVLDSDGQRIRTRVINGGALSDRKGVNVPDAVLPIPALTEKDKRDLA 180 G S+ +DDGK+R+KV+DS+ +IR +I GG LSDRKGVNVPD VLPIP LTEKD+RDL Sbjct: 121 GHSISMDDGKIRMKVIDSNPDQIRASIITGGPLSDRKGVNVPDVVLPIPILTEKDRRDLE 180 Query: 181 FALELGVDWIALSFVQRPEDVHEARALINGRAAVLSKLEKPAALDRLDEIVQASDAIMVA 240 FAL LGVDW+ALSFVQRPED+ EAR LI GRA +++KLEKPAALD LDEIV ASD++MVA Sbjct: 181 FALSLGVDWVALSFVQRPEDLVEARNLIAGRAGLMTKLEKPAALDHLDEIVMASDSVMVA 240 Query: 241 RGDLGVELPPERVPGTQKRILRVCRQHGRPIVIATQMLESMITSPVPTRAEVSDVAAAIY 300 RGDLGVELPPE+VPG QKRILR CR +G+P ++ATQMLESMI +P PTRAE SDVA+A+Y Sbjct: 241 RGDLGVELPPEKVPGAQKRILRACRHYGKPSIVATQMLESMIYAPTPTRAEASDVASAVY 300 Query: 301 DGSDAVMLSAESANGSYPLQAVAMMDRVISEVERDPLYRNMLDAQQETPQANSSDAICSA 360 DG+DAVMLSAESA+G+YP+QAV++MDR+I EVE DP+Y M++AQ E + SDAICSA Sbjct: 301 DGADAVMLSAESASGAYPVQAVSIMDRIIGEVENDPIYPMMINAQHEESLPSKSDAICSA 360 Query: 361 LRDVTRIVGATATVTYTSSGHTSLRAARERPMAPILSITPKIATARKLALVWGVHSTISD 420 LR V++++GA VTYT SG+TSLRAARERPMAPILSITP ++TAR+LALVWGVHST+ D Sbjct: 361 LRSVSQMIGAVVNVTYTDSGNTSLRAARERPMAPILSITPHLSTARRLALVWGVHSTVID 420 Query: 421 Q-IHNESEMVSAACQTALKEGFAKKGDQIAITAGMP 455 + + EMV AAC+TA EGFA+ GDQ+AI AGMP Sbjct: 421 HDVKDVDEMVDAACRTAFTEGFARPGDQLAIAAGMP 456 >C3X5Q6.1 C3X5Q6_OXAFO Pyruvate kinase EC=2.7.1.40 Length = 474 Score = 672 bits (1735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/456 (71%), Positives = 381/456 (83%), Gaps = 1/456 (0%) Query: 1 MRRQRQAKIVATLGPASATKDMIKALFEAGADVFRFNFSHGTHADHHARFEIVRAVEREV 60 MRRQR+AKIVATLGPAS+TK+MI +LFEAG DVFRFNFSHGT DH R E VR VER V Sbjct: 1 MRRQRKAKIVATLGPASSTKEMILSLFEAGVDVFRFNFSHGTQDDHRLRHEAVREVERLV 60 Query: 61 GRPIAILADLQGPKLRVGQFAEGKVQLEAGQEFVLDRDTTPGDNTRVCLPHAELFEVIAA 120 GRPIAILADLQGPKLR+G+FA GKVQL+ G EFV DR+T GD RV LPH ELF V+ A Sbjct: 61 GRPIAILADLQGPKLRIGKFASGKVQLKTGAEFVFDRNTADGDEQRVNLPHPELFGVMEA 120 Query: 121 GQSLLLDDGKLRLKVLDSDGQRIRTRVINGGALSDRKGVNVPDAVLPIPALTEKDKRDLA 180 G S+ LDDGKL++KV++S IRT+V+ GG LSDRKGVNVPD VLPIP LTEKD+RDL Sbjct: 121 GHSISLDDGKLKMKVMESTPDEIRTQVVTGGPLSDRKGVNVPDVVLPIPILTEKDRRDLE 180 Query: 181 FALELGVDWIALSFVQRPEDVHEARALINGRAAVLSKLEKPAALDRLDEIVQASDAIMVA 240 FAL LGVDW+ALSFVQRPED+ EAR LI GRA +++KLEKPAALD LDEIV ASD++MVA Sbjct: 181 FALSLGVDWVALSFVQRPEDLIEARRLIAGRAGLMTKLEKPAALDHLDEIVMASDSVMVA 240 Query: 241 RGDLGVELPPERVPGTQKRILRVCRQHGRPIVIATQMLESMITSPVPTRAEVSDVAAAIY 300 RGDLGVELPPE+VPG QKRILR CR +G+P ++ATQMLESMI SP PTRAE SDVA+A+Y Sbjct: 241 RGDLGVELPPEKVPGAQKRILRACRHYGKPSIVATQMLESMIFSPTPTRAEASDVASAVY 300 Query: 301 DGSDAVMLSAESANGSYPLQAVAMMDRVISEVERDPLYRNMLDAQQETPQANSSDAICSA 360 DG+DAVMLSAESA+G+YP+QAV++MDR+I EVE DP+Y M++AQ E + SDAICSA Sbjct: 301 DGADAVMLSAESASGAYPVQAVSIMDRIIGEVESDPIYPKMINAQHEVSLPSKSDAICSA 360 Query: 361 LRDVTRIVGATATVTYTSSGHTSLRAARERPMAPILSITPKIATARKLALVWGVHSTISD 420 LR V++++GA VTYT SG+TSLRAARERPMAPILSITP ++TAR+LAL WGVHST+ D Sbjct: 361 LRTVSQMIGAVVNVTYTDSGNTSLRAARERPMAPILSITPHLSTARRLALAWGVHSTVID 420 Query: 421 Q-IHNESEMVSAACQTALKEGFAKKGDQIAITAGMP 455 + + EMV AAC+TA EGFA+ GDQ+AI AGMP Sbjct: 421 HDVKDVDEMVDAACRTAFSEGFAQAGDQLAIAAGMP 456 >C6BH48.1 C6BH48_RALP1 Pyruvate kinase EC=2.7.1.40 Length = 492 Score = 667 bits (1720), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/455 (71%), Positives = 380/455 (83%) Query: 1 MRRQRQAKIVATLGPASATKDMIKALFEAGADVFRFNFSHGTHADHHARFEIVRAVEREV 60 MRR R KI+ATLGPAS+ KD I+ALF+AGADVFR NFSHG+H DH R++ VRAVE E Sbjct: 1 MRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVEAET 60 Query: 61 GRPIAILADLQGPKLRVGQFAEGKVQLEAGQEFVLDRDTTPGDNTRVCLPHAELFEVIAA 120 GRPI ILAD+QGPKLR+G FA+G+V L+ G FVLDRD TPGD TRV LPH EL+ A Sbjct: 61 GRPIGILADMQGPKLRIGTFADGRVVLKNGDRFVLDRDPTPGDVTRVHLPHPELYAATAP 120 Query: 121 GQSLLLDDGKLRLKVLDSDGQRIRTRVINGGALSDRKGVNVPDAVLPIPALTEKDKRDLA 180 GQSLLLDDGK+RL V +D I TRV++GG LSDRKGVNVPDAV+PIPALTEKD RDL Sbjct: 121 GQSLLLDDGKIRLAVEAADPTAIVTRVVDGGPLSDRKGVNVPDAVIPIPALTEKDLRDLD 180 Query: 181 FALELGVDWIALSFVQRPEDVHEARALINGRAAVLSKLEKPAALDRLDEIVQASDAIMVA 240 FAL LGVDWIALSFVQR EDV AR +I RA +LSK+EKPAAL L++IVQASDA+MVA Sbjct: 181 FALSLGVDWIALSFVQRAEDVIAAREIIGDRAGLLSKIEKPAALLHLEDIVQASDALMVA 240 Query: 241 RGDLGVELPPERVPGTQKRILRVCRQHGRPIVIATQMLESMITSPVPTRAEVSDVAAAIY 300 RGDLGVELPPERVPG QKRILR+ RQHG+P+V+ATQMLESMI +PVPTRAE SDVA+A+Y Sbjct: 241 RGDLGVELPPERVPGVQKRILRMARQHGKPVVVATQMLESMIEAPVPTRAEASDVASAVY 300 Query: 301 DGSDAVMLSAESANGSYPLQAVAMMDRVISEVERDPLYRNMLDAQQETPQANSSDAICSA 360 DG+DAVMLSAESA+G +P+ AV++M+R+I+E ERDPLYRN++DAQ + P DAIC+A Sbjct: 301 DGTDAVMLSAESASGKHPVAAVSIMNRIIAETERDPLYRNLIDAQHQPPLPTRQDAICAA 360 Query: 361 LRDVTRIVGATATVTYTSSGHTSLRAARERPMAPILSITPKIATARKLALVWGVHSTISD 420 LRDVT I+GA ATVTYTSSG TSLRAARERP+API+SITP++ TAR+LA+ WGVHST+S Sbjct: 361 LRDVTHILGAVATVTYTSSGKTSLRAARERPLAPIVSITPRLDTARRLAITWGVHSTVSP 420 Query: 421 QIHNESEMVSAACQTALKEGFAKKGDQIAITAGMP 455 + N EMV AAC+ A +EGFA GDQIAITAGMP Sbjct: 421 DVSNVDEMVDAACRAAAREGFAVSGDQIAITAGMP 455 >Q1LHQ2.1 Q1LHQ2_RALME Pyruvate kinase EC=2.7.1.40 Length = 488 Score = 666 bits (1719), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/459 (71%), Positives = 375/459 (81%) Query: 1 MRRQRQAKIVATLGPASATKDMIKALFEAGADVFRFNFSHGTHADHHARFEIVRAVEREV 60 MRRQR+AKIVATLGPAS +I+ LF+AGADVFR NFSHGTH DH AR++ VR VE E Sbjct: 1 MRRQRKAKIVATLGPASTDIAVIRQLFDAGADVFRLNFSHGTHEDHRARYDAVRQVEAET 60 Query: 61 GRPIAILADLQGPKLRVGQFAEGKVQLEAGQEFVLDRDTTPGDNTRVCLPHAELFEVIAA 120 GRPIAILADLQGPKLR+G FA GKV + AG FVLD D TPGD RV LPH ELF+ A Sbjct: 61 GRPIAILADLQGPKLRIGTFAAGKVAVSAGDTFVLDSDPTPGDAKRVYLPHPELFKAANA 120 Query: 121 GQSLLLDDGKLRLKVLDSDGQRIRTRVINGGALSDRKGVNVPDAVLPIPALTEKDKRDLA 180 GQSLL+DDGK+RL + I TRV N G LSDRKGVNVPDAV+PIPALTEKD++DLA Sbjct: 121 GQSLLIDDGKVRLNIESVASGSITTRVANNGTLSDRKGVNVPDAVIPIPALTEKDRKDLA 180 Query: 181 FALELGVDWIALSFVQRPEDVHEARALINGRAAVLSKLEKPAALDRLDEIVQASDAIMVA 240 FALELG DWIALSFVQRP D+ EAR LI RA VLSK+EKPAAL +L+EIV+ SDA+MVA Sbjct: 181 FALELGADWIALSFVQRPSDILEARELIGTRAGVLSKIEKPAALQQLEEIVRVSDAVMVA 240 Query: 241 RGDLGVELPPERVPGTQKRILRVCRQHGRPIVIATQMLESMITSPVPTRAEVSDVAAAIY 300 RGDLGVELPPERVPG QKRILR+CRQ G+PIVIATQMLESMI SPVPTRAE SDVA+AIY Sbjct: 241 RGDLGVELPPERVPGVQKRILRICRQLGKPIVIATQMLESMIDSPVPTRAEASDVASAIY 300 Query: 301 DGSDAVMLSAESANGSYPLQAVAMMDRVISEVERDPLYRNMLDAQQETPQANSSDAICSA 360 DG+DAVMLSAESANG +P+ AV++M+R+I+EVE DPLYRNM+DAQ E P + DAIC+A Sbjct: 301 DGADAVMLSAESANGRHPVAAVSIMNRIITEVENDPLYRNMIDAQHEAPLSTRQDAICAA 360 Query: 361 LRDVTRIVGATATVTYTSSGHTSLRAARERPMAPILSITPKIATARKLALVWGVHSTISD 420 LR+VT+I+GA ATVTYTSSG T+LRAARERP API+SITP + AR+LA+ WGVHST+S Sbjct: 361 LREVTQIIGAKATVTYTSSGATALRAARERPCAPIVSITPNLEIARRLAITWGVHSTVSP 420 Query: 421 QIHNESEMVSAACQTALKEGFAKKGDQIAITAGMPXPSG 459 + + EMV AA + AL EG+A GDQI I AGMP G Sbjct: 421 DVQSVDEMVEAAARAALVEGYAAPGDQITIAAGMPFGQG 459 >E2SXG6.1 E2SXG6_9RALS Pyruvate kinase EC=2.7.1.40 Length = 492 Score = 666 bits (1718), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/455 (71%), Positives = 380/455 (83%) Query: 1 MRRQRQAKIVATLGPASATKDMIKALFEAGADVFRFNFSHGTHADHHARFEIVRAVEREV 60 MRR R KI+ATLGPAS+ KD I+ALF+AGADVFR NFSHG+H DH R++ VRAVE E Sbjct: 1 MRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVEAET 60 Query: 61 GRPIAILADLQGPKLRVGQFAEGKVQLEAGQEFVLDRDTTPGDNTRVCLPHAELFEVIAA 120 GRPI ILAD+QGPKLR+G FA+G+V L+ G FVLDRD TPGD TRV LPH EL+ A Sbjct: 61 GRPIGILADMQGPKLRIGTFADGRVVLKNGDRFVLDRDPTPGDVTRVHLPHPELYAATAP 120 Query: 121 GQSLLLDDGKLRLKVLDSDGQRIRTRVINGGALSDRKGVNVPDAVLPIPALTEKDKRDLA 180 GQSLLLDDGK+RL V +D I TRV++GG LSDRKGVNVPDAV+PIPALTEKD RDL Sbjct: 121 GQSLLLDDGKIRLAVEAADPTAIVTRVVDGGPLSDRKGVNVPDAVIPIPALTEKDLRDLD 180 Query: 181 FALELGVDWIALSFVQRPEDVHEARALINGRAAVLSKLEKPAALDRLDEIVQASDAIMVA 240 FAL LGVDWIALSFVQR EDV AR +I RA +LSK+EKPAAL L++IVQASDA+MVA Sbjct: 181 FALSLGVDWIALSFVQRAEDVIAAREIIGDRAGLLSKIEKPAALLHLEDIVQASDALMVA 240 Query: 241 RGDLGVELPPERVPGTQKRILRVCRQHGRPIVIATQMLESMITSPVPTRAEVSDVAAAIY 300 RGDLGVELPPERVPG QKRILR+ RQHG+P+V+ATQMLESMI +PVPTRAE SDVA+A+Y Sbjct: 241 RGDLGVELPPERVPGVQKRILRMARQHGKPVVVATQMLESMIEAPVPTRAEASDVASAVY 300 Query: 301 DGSDAVMLSAESANGSYPLQAVAMMDRVISEVERDPLYRNMLDAQQETPQANSSDAICSA 360 DG+DAVMLSAESA+G +P+ AV++M+R+I+E ERDPLYRN++DAQ + P DAIC+A Sbjct: 301 DGTDAVMLSAESASGKHPVAAVSIMNRIIAETERDPLYRNLIDAQHQPPLPTRQDAICAA 360 Query: 361 LRDVTRIVGATATVTYTSSGHTSLRAARERPMAPILSITPKIATARKLALVWGVHSTISD 420 LRDVT I+GA ATVTYTSSG TSLRAARERP+API+SITP++ TAR+LA+ WGVHST+S Sbjct: 361 LRDVTHILGAVATVTYTSSGKTSLRAARERPLAPIVSITPRLDTARRLAITWGVHSTVSL 420 Query: 421 QIHNESEMVSAACQTALKEGFAKKGDQIAITAGMP 455 + N EMV AAC+ A +EGFA GDQIAITAGMP Sbjct: 421 DVSNVDEMVDAACRAAAREGFAVSGDQIAITAGMP 455