BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0088.p (421 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6SUX5.1 A6SUX5_JANMA Hydroxypyruvate reductase EC=1.1.1.81 643 0.0 F1VVR0.1 F1VVR0_9BURK D-glycerate 2-kinase 625 e-177 C3X5Q7.1 C3X5Q7_OXAFO Hydroxypyruvate reductase 616 e-174 A4G222.1 A4G222_HERAR Putative hydroxypyruvate reductase EC=1.1.... 614 e-173 C3XBY0.1 C3XBY0_OXAFO Hydroxypyruvate reductase 607 e-172 >A6SUX5.1 A6SUX5_JANMA Hydroxypyruvate reductase EC=1.1.1.81 Length = 421 Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/421 (77%), Positives = 371/421 (88%) Query: 1 MLNNPRQFLLDLYTAAVSAVSAEKSLPTFLPEPPKQGRTIVIGAGKGAAAMAKTVEQHWP 60 M +PRQFL DLY AV AVSA+K +P +LP+ +GRT+VIGAGKGAAAMAK VE WP Sbjct: 1 MSIDPRQFLNDLYATAVEAVSAQKCMPAYLPKQSAKGRTLVIGAGKGAAAMAKVVEDTWP 60 Query: 61 GKISGLVVTRYGHGADCKQIEVVEASHPVPDEAGRQAAARMLAMANGLTKDDLVLCLISG 120 GK+ GL+VTRYGHGADCKQIEVVEA+HPVPDEAGRQAA RML + GLT+DDLVLCLI+G Sbjct: 61 GKVEGLIVTRYGHGADCKQIEVVEAAHPVPDEAGRQAAGRMLELVKGLTEDDLVLCLITG 120 Query: 121 GGSALLALPAEGITLAQKQAINKALLNSGANIFEMNCVRKHLSAIKGGRLALACAPARVV 180 GGSALL+LP EGITL QKQA+NKALL SGA I EMNCVRKHLSAIKGGRLALACAPARVV Sbjct: 121 GGSALLSLPGEGITLEQKQALNKALLKSGATISEMNCVRKHLSAIKGGRLALACAPARVV 180 Query: 181 TLMISDIPGDDPGIIASGPTLPDATTCAEALAVLRKYKIDVPPSVQVHLESGIGETPKPG 240 TL+ISD+PGDDPG+IASGPTLPD TTCAE+LA+L+KY I++P ++ HLESG GETPKPG Sbjct: 181 TLLISDVPGDDPGVIASGPTLPDPTTCAESLAILKKYGIEIPDNILKHLESGAGETPKPG 240 Query: 241 DARLAANEHHVIATAQQALQAAATAARAVGVTPYILSDDMEGEARDIGLAHAAIARQIAR 300 D R A NEHHV+ATAQ AL+AAA ARA G+TPYILS+D+EGE+RD+G+ HAA+A+Q+A+ Sbjct: 241 DPRFARNEHHVMATAQHALEAAAAKARAAGITPYILSNDLEGESRDVGMVHAALAKQVAK 300 Query: 301 YDQPFKKPCVLISGGETTVTVRGTGRGGRNAEFLLSLANALNGAPGMHAIACDTDGIDGS 360 Y QPF KPCV++SGGETTVTVRG GRGGRNAEFLLSLA +L G G+HA+ACDTDGIDGS Sbjct: 301 YGQPFAKPCVILSGGETTVTVRGKGRGGRNAEFLLSLAVSLQGTAGIHALACDTDGIDGS 360 Query: 361 EDNAGAIYQPDSMQRAEQLGLNPKALLENNDGYGFFSALGDLVVSGPTRTNVNDFRAILI 420 EDNAGAIYQPDS RA + GLN KA+LENNDGYGFFSALGDL+VSGPTRTNVNDFRAILI Sbjct: 361 EDNAGAIYQPDSWTRATEQGLNAKAMLENNDGYGFFSALGDLIVSGPTRTNVNDFRAILI 420 Query: 421 L 421 L Sbjct: 421 L 421 >F1VVR0.1 F1VVR0_9BURK D-glycerate 2-kinase Length = 424 Score = 625 bits (1613), Expect = e-177, Method: Compositional matrix adjust. Identities = 333/417 (79%), Positives = 367/417 (88%) Query: 5 PRQFLLDLYTAAVSAVSAEKSLPTFLPEPPKQGRTIVIGAGKGAAAMAKTVEQHWPGKIS 64 PRQFLLDLY +AV+AVS K LP FLP PP GRT+VIGAGKGAAAMA+TVEQHWPG++S Sbjct: 8 PRQFLLDLYASAVAAVSPAKCLPAFLPPPPSTGRTLVIGAGKGAAAMARTVEQHWPGELS 67 Query: 65 GLVVTRYGHGADCKQIEVVEASHPVPDEAGRQAAARMLAMANGLTKDDLVLCLISGGGSA 124 GLVVTRYGHGADC++IEVVEA+HPVPDEAGRQAAARML + GL+ DDLVLCLISGGGS+ Sbjct: 68 GLVVTRYGHGADCQRIEVVEAAHPVPDEAGRQAAARMLQLVQGLSADDLVLCLISGGGSS 127 Query: 125 LLALPAEGITLAQKQAINKALLNSGANIFEMNCVRKHLSAIKGGRLALACAPARVVTLMI 184 LLALP EGITL QKQAINKALL SGA I EMNCVRKHLSAIKGGRLALACAPARVVTL+I Sbjct: 128 LLALPGEGITLEQKQAINKALLRSGAAIGEMNCVRKHLSAIKGGRLALACAPARVVTLLI 187 Query: 185 SDIPGDDPGIIASGPTLPDATTCAEALAVLRKYKIDVPPSVQVHLESGIGETPKPGDARL 244 SD+PGD+PG+IASGPTL D TTCAEALAVL KY I +P SV+ HL+SG GETPKPGDAR Sbjct: 188 SDVPGDEPGVIASGPTLADPTTCAEALAVLDKYAIAIPGSVRAHLQSGAGETPKPGDARF 247 Query: 245 AANEHHVIATAQQALQAAATAARAVGVTPYILSDDMEGEARDIGLAHAAIARQIARYDQP 304 A NE+H+IATAQ AL+AAA A+A G+ YILSD +EGEARDI L HAA+ARQIA QP Sbjct: 248 ARNEYHIIATAQHALEAAAATAQAAGIPAYILSDGIEGEARDIALMHAALARQIAARGQP 307 Query: 305 FKKPCVLISGGETTVTVRGTGRGGRNAEFLLSLANALNGAPGMHAIACDTDGIDGSEDNA 364 F++PCVLISGGETTVTVRG+GRGGRNAEFLLSLA AL+GA +HAIACDTDGIDGSEDNA Sbjct: 308 FQRPCVLISGGETTVTVRGSGRGGRNAEFLLSLAVALDGAADIHAIACDTDGIDGSEDNA 367 Query: 365 GAIYQPDSMQRAEQLGLNPKALLENNDGYGFFSALGDLVVSGPTRTNVNDFRAILIL 421 GA+ QPDS+ RA LG+ K LLENNDGYGFFSAL DLVVSGPTRTNVNDFRAILIL Sbjct: 368 GALLQPDSLARAAALGMRAKTLLENNDGYGFFSALDDLVVSGPTRTNVNDFRAILIL 424 >C3X5Q7.1 C3X5Q7_OXAFO Hydroxypyruvate reductase Length = 422 Score = 616 bits (1589), Expect = e-174, Method: Compositional matrix adjust. Identities = 318/420 (75%), Positives = 359/420 (85%) Query: 2 LNNPRQFLLDLYTAAVSAVSAEKSLPTFLPEPPKQGRTIVIGAGKGAAAMAKTVEQHWPG 61 ++NP+QFLLDLY++A+SAVSA K LP +LPEP GRTIVIGAGKGAAAMAK VE HW G Sbjct: 3 IDNPKQFLLDLYSSAISAVSAAKCLPQYLPEPLPGGRTIVIGAGKGAAAMAKAVEDHWQG 62 Query: 62 KISGLVVTRYGHGADCKQIEVVEASHPVPDEAGRQAAARMLAMANGLTKDDLVLCLISGG 121 ++SGLVVTRY HG CK IEVVEASHPVPD AGR AA RML M GL+ DLV+CL+SGG Sbjct: 63 ELSGLVVTRYEHGLPCKHIEVVEASHPVPDAAGRDAAKRMLQMVQGLSDKDLVICLVSGG 122 Query: 122 GSALLALPAEGITLAQKQAINKALLNSGANIFEMNCVRKHLSAIKGGRLALACAPARVVT 181 GSALLALP++ I+L QKQ IN+ LL SGA+I EMNCVRKHLS IKGGRLALACAPA+VVT Sbjct: 123 GSALLALPSKNISLEQKQQINRKLLRSGASISEMNCVRKHLSDIKGGRLALACAPAKVVT 182 Query: 182 LMISDIPGDDPGIIASGPTLPDATTCAEALAVLRKYKIDVPPSVQVHLESGIGETPKPGD 241 LMISDIPGDDPGIIASGPTLPD TTC +ALA+L+KY+IDVP +V HLESG GETPKPGD Sbjct: 183 LMISDIPGDDPGIIASGPTLPDPTTCEDALAILQKYQIDVPENVLRHLESGEGETPKPGD 242 Query: 242 ARLAANEHHVIATAQQALQAAATAARAVGVTPYILSDDMEGEARDIGLAHAAIARQIARY 301 R A NE H+IATAQ AL+AAA ARA GV PYILSD +EGEARDI L HAA+ARQ+ Sbjct: 243 PRFARNESHIIATAQDALEAAADMARASGVRPYILSDSIEGEARDIALMHAAMARQVIER 302 Query: 302 DQPFKKPCVLISGGETTVTVRGTGRGGRNAEFLLSLANALNGAPGMHAIACDTDGIDGSE 361 DQPF+KPCV+ISGGETTVTV+G GRGGRNAEFLLSLA ALN PG++AIACDTDGIDGSE Sbjct: 303 DQPFQKPCVIISGGETTVTVKGNGRGGRNAEFLLSLAIALNDQPGVYAIACDTDGIDGSE 362 Query: 362 DNAGAIYQPDSMQRAEQLGLNPKALLENNDGYGFFSALGDLVVSGPTRTNVNDFRAILIL 421 DNAGA+Y P S+ RAE G P+ +LENNDGYGFFSALG+LVV+GP+RTNVNDFRAILI+ Sbjct: 363 DNAGALYMPGSLSRAESQGKRPRKMLENNDGYGFFSALGNLVVTGPSRTNVNDFRAILII 422 >A4G222.1 A4G222_HERAR Putative hydroxypyruvate reductase EC=1.1.1.81 Length = 396 Score = 614 bits (1583), Expect = e-173, Method: Compositional matrix adjust. Identities = 311/396 (78%), Positives = 354/396 (89%) Query: 26 LPTFLPEPPKQGRTIVIGAGKGAAAMAKTVEQHWPGKISGLVVTRYGHGADCKQIEVVEA 85 +P +LP+ +GRT+VIGAGKGAAAMAK VE WPGK+ GL+VTRYGHGADCKQIEVVEA Sbjct: 1 MPAYLPKQSVKGRTLVIGAGKGAAAMAKVVEDTWPGKVEGLIVTRYGHGADCKQIEVVEA 60 Query: 86 SHPVPDEAGRQAAARMLAMANGLTKDDLVLCLISGGGSALLALPAEGITLAQKQAINKAL 145 +HPVPDEAGRQAA RML + GLT+DDLVLCLI+GGGSALL+LP EGI+L QKQA+NKAL Sbjct: 61 AHPVPDEAGRQAAGRMLELVKGLTEDDLVLCLITGGGSALLSLPGEGISLEQKQALNKAL 120 Query: 146 LNSGANIFEMNCVRKHLSAIKGGRLALACAPARVVTLMISDIPGDDPGIIASGPTLPDAT 205 L SGA I EMNCVRKHLSAIKGGRL LACAPARVVTL+ISD+PGDDPG+IASGPTLPD T Sbjct: 121 LKSGATISEMNCVRKHLSAIKGGRLGLACAPARVVTLLISDVPGDDPGVIASGPTLPDPT 180 Query: 206 TCAEALAVLRKYKIDVPPSVQVHLESGIGETPKPGDARLAANEHHVIATAQQALQAAATA 265 TCAE+LA+L+KYKI++P ++ HLESG GETPKPGDAR A NEHHVIATAQ AL+AAA Sbjct: 181 TCAESLAILKKYKIEIPDNILKHLESGAGETPKPGDARFARNEHHVIATAQHALEAAAEK 240 Query: 266 ARAVGVTPYILSDDMEGEARDIGLAHAAIARQIARYDQPFKKPCVLISGGETTVTVRGTG 325 ARA G+TPYILS+D+EGE+RD+GL HAA+A+Q+A+Y QPF KPCV++SGGETTVTVRG G Sbjct: 241 ARAAGITPYILSNDLEGESRDVGLVHAALAKQVAKYGQPFAKPCVILSGGETTVTVRGKG 300 Query: 326 RGGRNAEFLLSLANALNGAPGMHAIACDTDGIDGSEDNAGAIYQPDSMQRAEQLGLNPKA 385 RGGRNAEFLLSLA ALNGAP ++A+ACDTDGIDGSEDNAGAIYQPDS+ RA G N K Sbjct: 301 RGGRNAEFLLSLAVALNGAPDIYALACDTDGIDGSEDNAGAIYQPDSIARAAAAGHNAKT 360 Query: 386 LLENNDGYGFFSALGDLVVSGPTRTNVNDFRAILIL 421 +LENNDGYGFFSA+GDL+VSGPTRTNVNDFRAILIL Sbjct: 361 MLENNDGYGFFSAVGDLIVSGPTRTNVNDFRAILIL 396 >C3XBY0.1 C3XBY0_OXAFO Hydroxypyruvate reductase Length = 422 Score = 607 bits (1566), Expect = e-172, Method: Compositional matrix adjust. Identities = 315/420 (75%), Positives = 365/420 (86%) Query: 2 LNNPRQFLLDLYTAAVSAVSAEKSLPTFLPEPPKQGRTIVIGAGKGAAAMAKTVEQHWPG 61 ++NP+QFLLDLY++A+SAVSAEK LP +LP+P GRTIVIGAGKGAAAMAK VE HW G Sbjct: 3 IDNPKQFLLDLYSSAISAVSAEKCLPQYLPKPVPGGRTIVIGAGKGAAAMAKAVEDHWDG 62 Query: 62 KISGLVVTRYGHGADCKQIEVVEASHPVPDEAGRQAAARMLAMANGLTKDDLVLCLISGG 121 ++SGLVVTRY HG CK IEVVEASHPVPD AGR AA RML M GLT+ DLV+CL+SGG Sbjct: 63 ELSGLVVTRYEHGLPCKHIEVVEASHPVPDAAGRDAAKRMLEMVKGLTEKDLVICLVSGG 122 Query: 122 GSALLALPAEGITLAQKQAINKALLNSGANIFEMNCVRKHLSAIKGGRLALACAPARVVT 181 GSALLALPA+ ITL +KQ IN+ LL SGA+I EMNCVRKHLS IKGGRLALACAPA+VVT Sbjct: 123 GSALLALPAKNITLEEKQQINRKLLRSGASISEMNCVRKHLSDIKGGRLALACAPAKVVT 182 Query: 182 LMISDIPGDDPGIIASGPTLPDATTCAEALAVLRKYKIDVPPSVQVHLESGIGETPKPGD 241 L+ISDIPGDDPGIIASGPTLPD TTC +ALA+L+KY+IDVP +V HLESG GETPKPGD Sbjct: 183 LLISDIPGDDPGIIASGPTLPDPTTCEDALAILKKYQIDVPANVVKHLESGEGETPKPGD 242 Query: 242 ARLAANEHHVIATAQQALQAAATAARAVGVTPYILSDDMEGEARDIGLAHAAIARQIARY 301 R A NE+H+IATAQ+AL+AAA ARA G+TPYILSD +EGE+RDI L HAA+A+Q+ Sbjct: 243 PRFARNENHIIATAQEALEAAAEMARAQGITPYILSDRIEGESRDIALMHAAMAKQVIDR 302 Query: 302 DQPFKKPCVLISGGETTVTVRGTGRGGRNAEFLLSLANALNGAPGMHAIACDTDGIDGSE 361 +QPF+KPCV+ISGGETTVTV+G GRGGRNAEFLLSLA AL+ PG++AIACDTDGIDGSE Sbjct: 303 NQPFEKPCVIISGGETTVTVKGNGRGGRNAEFLLSLAIALDKEPGVYAIACDTDGIDGSE 362 Query: 362 DNAGAIYQPDSMQRAEQLGLNPKALLENNDGYGFFSALGDLVVSGPTRTNVNDFRAILIL 421 DNAGA+Y PDS+ RAE+ G+ P+ LLENNDGYGFF AL DL+V+GP+RTNVNDFRAILI+ Sbjct: 363 DNAGAVYAPDSVARAEEKGIRPRKLLENNDGYGFFDALDDLIVTGPSRTNVNDFRAILII 422