BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0025.0052.p         (204 letters)

Database: pfamseq 
           15,929,002 sequences; 5,169,768,107 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D8J1Y7.1 D8J1Y7_HERSS Bifunctional folylpolyglutamate synthase/d...   268   4e-70
A4G4G5.1 A4G4G5_HERAR FolC bifunctional protein EC=6.3.2.12           226   2e-57
A6T004.1 A6T004_JANMA Bifunctional folylpolyglutamate synthase /...   224   6e-57
F1VXH5.1 F1VXH5_9BURK Dihydrofolate synthase                          216   2e-54
C3X4N1.1 C3X4N1_OXAFO Bifunctional folylpolyglutamate synthase/d...   202   3e-50

>D8J1Y7.1 D8J1Y7_HERSS Bifunctional folylpolyglutamate synthase/dihydrofolate
           synthase protein EC=6.3.2.12 EC=6.3.2.17
          Length = 437

 Score =  268 bits (684), Expect = 4e-70,   Method: Compositional matrix adjust.
 Identities = 129/154 (83%), Positives = 138/154 (89%)

Query: 2   QAQAKPSTLAEWLTLLETRHTKSIDMGLERVGKVKEQLGIHFDCPVIMVAGTNGKGSTCA 61
           QA   P+TL EWL LLE RH K IDMGLERV +VK++L IHFDCPVIMVAGTNGKGSTCA
Sbjct: 4   QASPTPTTLNEWLALLEQRHFKQIDMGLERVMQVKQKLDIHFDCPVIMVAGTNGKGSTCA 63

Query: 62  MLESILMRAGYRVGLYIKPHFLHFNERARIEGIPASDAALIAAFEAVEEKRGDISLTYFE 121
           MLESIL+RAGYRVGLY+KPHFLHFNERAR+ G  ASDA LIAAFEAVE +RGDISLTYFE
Sbjct: 64  MLESILLRAGYRVGLYMKPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLTYFE 123

Query: 122 FTTLAIMKLLADAKMDVVILEVGLGGRLDAVNVI 155
           FTTLAIMKLLADA+ DVVILEVGLGGRLDAVNVI
Sbjct: 124 FTTLAIMKLLADARQDVVILEVGLGGRLDAVNVI 157


>A4G4G5.1 A4G4G5_HERAR FolC bifunctional protein EC=6.3.2.12
          Length = 433

 Score =  226 bits (575), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 105/149 (70%), Positives = 123/149 (82%)

Query: 7   PSTLAEWLTLLETRHTKSIDMGLERVGKVKEQLGIHFDCPVIMVAGTNGKGSTCAMLESI 66
           PS LAEWL  LET H K+IDMGL+RV +VK+ + + F CPVI+V GTNGKGSTCAMLESI
Sbjct: 5   PSNLAEWLAHLETMHPKAIDMGLDRVRQVKQAMTVEFTCPVIIVGGTNGKGSTCAMLESI 64

Query: 67  LMRAGYRVGLYIKPHFLHFNERARIEGIPASDAALIAAFEAVEEKRGDISLTYFEFTTLA 126
           L+RAGYRVGLY  PH LHFNER RI G  ASDA L+AAF+ +E  RGD+SL+YFEFTTLA
Sbjct: 65  LLRAGYRVGLYTSPHLLHFNERMRINGESASDAELLAAFDKLEAVRGDVSLSYFEFTTLA 124

Query: 127 IMKLLADAKMDVVILEVGLGGRLDAVNVI 155
            ++L +DAK+D VI EVGLGGRLDAVNV+
Sbjct: 125 AIQLFSDAKLDAVIFEVGLGGRLDAVNVL 153


>A6T004.1 A6T004_JANMA Bifunctional folylpolyglutamate synthase /
           dihydrofolate synthase EC=6.3.2.12 EC=6.3.2.17
          Length = 432

 Score =  224 bits (571), Expect = 6e-57,   Method: Compositional matrix adjust.
 Identities = 102/150 (68%), Positives = 122/150 (81%)

Query: 6   KPSTLAEWLTLLETRHTKSIDMGLERVGKVKEQLGIHFDCPVIMVAGTNGKGSTCAMLES 65
            P TLA+WLT LE  H K+IDMGL+RV +VK+ + + F CPVI+V GTNGKGSTCAMLES
Sbjct: 3   NPKTLADWLTRLEALHPKAIDMGLDRVREVKQAMDVQFACPVIIVGGTNGKGSTCAMLES 62

Query: 66  ILMRAGYRVGLYIKPHFLHFNERARIEGIPASDAALIAAFEAVEEKRGDISLTYFEFTTL 125
           IL+RAGYRVGLY  PH LHFNER R+ G+  +D  LIAAF+ +E  RGD+SL+YFEFTTL
Sbjct: 63  ILLRAGYRVGLYTSPHLLHFNERMRVNGVSCTDQELIAAFDKLEAVRGDVSLSYFEFTTL 122

Query: 126 AIMKLLADAKMDVVILEVGLGGRLDAVNVI 155
           A ++L ADAK+D VI EVGLGGRLDAVNV+
Sbjct: 123 AAIQLFADAKLDAVIFEVGLGGRLDAVNVL 152


>F1VXH5.1 F1VXH5_9BURK Dihydrofolate synthase
          Length = 433

 Score =  216 bits (549), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 101/149 (67%), Positives = 121/149 (81%)

Query: 7   PSTLAEWLTLLETRHTKSIDMGLERVGKVKEQLGIHFDCPVIMVAGTNGKGSTCAMLESI 66
           P TLA WLT LE++H  +IDMGL+RV  V  ++GI FDCPVI V GTNGKGSTCAMLE+I
Sbjct: 5   PDTLAGWLTRLESQHPITIDMGLDRVSAVAVRMGIRFDCPVITVGGTNGKGSTCAMLEAI 64

Query: 67  LMRAGYRVGLYIKPHFLHFNERARIEGIPASDAALIAAFEAVEEKRGDISLTYFEFTTLA 126
           L++AGYRVGL   PH + FNERAR+ G  ASDA L+  F  VE+ RGDISL+YFEFTTLA
Sbjct: 65  LLQAGYRVGLSTSPHLIDFNERARVAGESASDAELVRYFGVVEQARGDISLSYFEFTTLA 124

Query: 127 IMKLLADAKMDVVILEVGLGGRLDAVNVI 155
           I++L  DA++DVVILEVGLGGRLDA+N+I
Sbjct: 125 ILQLFVDARLDVVILEVGLGGRLDAMNII 153


>C3X4N1.1 C3X4N1_OXAFO Bifunctional folylpolyglutamate synthase/dihydrofolate
           synthase
          Length = 438

 Score =  202 bits (513), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 91/147 (61%), Positives = 115/147 (78%)

Query: 9   TLAEWLTLLETRHTKSIDMGLERVGKVKEQLGIHFDCPVIMVAGTNGKGSTCAMLESILM 68
           +LAEW  L+E+ H K+I+MGL+R+  VKE+LG+ FDCPV+ V GTNGKGSTCAML++I  
Sbjct: 12  SLAEWTRLVESLHPKNIEMGLDRIRVVKERLGLRFDCPVVTVGGTNGKGSTCAMLQAIWK 71

Query: 69  RAGYRVGLYIKPHFLHFNERARIEGIPASDAALIAAFEAVEEKRGDISLTYFEFTTLAIM 128
            AGYR GLY  PH   FNER +I+G    D  L+A FE +E  RGDI+LT+FEFTTL  +
Sbjct: 72  EAGYRTGLYTSPHIHRFNERMKIDGKMVDDETLVACFEEIEAARGDIALTFFEFTTLVAL 131

Query: 129 KLLADAKMDVVILEVGLGGRLDAVNVI 155
           KL +DAK+DV++LEVGLGGRLDAVN+I
Sbjct: 132 KLFSDAKLDVIVLEVGLGGRLDAVNLI 158