BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0044.p (368 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1Z4.1 D8J1Z4_HERSS Aspartate-semialdehyde dehydrogenase EC=1.... 714 0.0 A2RPT7.1 A2RPT7_HERSE Aspartate-semialdehyde dehydrogenase EC=1.... 714 0.0 A4G4F8.1 A4G4F8_HERAR Aspartate-semialdehyde dehydrogenase EC=1.... 677 0.0 A6T011.1 A6T011_JANMA Aspartate-semialdehyde dehydrogenase EC=1.... 665 0.0 D8NAQ8.1 D8NAQ8_RALSO Aspartate-semialdehyde dehydrogenase EC=1.... 637 e-180 >D8J1Z4.1 D8J1Z4_HERSS Aspartate-semialdehyde dehydrogenase EC=1.2.1.11 Length = 371 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/367 (95%), Positives = 360/367 (98%) Query: 1 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAKTATTLKDANSI 60 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAK TTLKDANSI Sbjct: 2 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAKKETTLKDANSI 61 Query: 61 DELKKCDIIITAQGGDYTTEIFPKLRAAGWNGFWIDAASTLRMKDDAVIVLDPVNDNVIR 120 DELKKCDIIITAQGGDYT EIFPKLRAAGW+G+WIDAAS+LRMKDDAVIVLDPVN+NVI+ Sbjct: 62 DELKKCDIIITAQGGDYTNEIFPKLRAAGWDGYWIDAASSLRMKDDAVIVLDPVNNNVIK 121 Query: 121 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG 180 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG Sbjct: 122 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG 181 Query: 181 VISAAVTDELATPSSAILDIDRVVAKTIREDVPTEYFGAPLAGGLIPWIDAQLENGQSKE 240 VI+AAV DELATPSSAILDIDR VAKTIREDVPTE+FGAPLAGGLIPWIDAQLENGQSKE Sbjct: 182 VINAAVADELATPSSAILDIDRKVAKTIREDVPTEFFGAPLAGGLIPWIDAQLENGQSKE 241 Query: 241 EWKGQAEVNKILGNDKPIPVDGLCVRIGAMRCHSLALTIKLKRDLPLSEIESIIRAGNQW 300 EWKGQAEVNKILGN++ IPVDGLCVRIGAMRCHSLALTIKLKRDLPL+EIESIIRAGNQW Sbjct: 242 EWKGQAEVNKILGNEQIIPVDGLCVRIGAMRCHSLALTIKLKRDLPLAEIESIIRAGNQW 301 Query: 301 VKWVPNDRAITVKELTPASITGSLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 360 VKWVPNDRAITVKELTPASITG LEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR Sbjct: 302 VKWVPNDRAITVKELTPASITGGLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 361 Query: 361 MLRIILG 367 MLRIILG Sbjct: 362 MLRIILG 368 >A2RPT7.1 A2RPT7_HERSE Aspartate-semialdehyde dehydrogenase EC=1.2.1.11 Length = 371 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/367 (95%), Positives = 360/367 (98%) Query: 1 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAKTATTLKDANSI 60 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAK TTLKDANSI Sbjct: 2 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAKKETTLKDANSI 61 Query: 61 DELKKCDIIITAQGGDYTTEIFPKLRAAGWNGFWIDAASTLRMKDDAVIVLDPVNDNVIR 120 DELKKCDIIITAQGGDYT EIFPKLRAAGW+G+WIDAAS+LRMKDDAVIVLDPVN+NVI+ Sbjct: 62 DELKKCDIIITAQGGDYTNEIFPKLRAAGWDGYWIDAASSLRMKDDAVIVLDPVNNNVIK 121 Query: 121 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG 180 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG Sbjct: 122 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG 181 Query: 181 VISAAVTDELATPSSAILDIDRVVAKTIREDVPTEYFGAPLAGGLIPWIDAQLENGQSKE 240 VI+AAV DELATPSSAILDIDR VAKTIREDVPTE+FGAPLAGGLIPWIDAQLENGQSKE Sbjct: 182 VINAAVADELATPSSAILDIDRKVAKTIREDVPTEFFGAPLAGGLIPWIDAQLENGQSKE 241 Query: 241 EWKGQAEVNKILGNDKPIPVDGLCVRIGAMRCHSLALTIKLKRDLPLSEIESIIRAGNQW 300 EWKGQAEVNKILGN++ IPVDGLCVRIGAMRCHSLALTIKLKRDLPL+EIESIIRAGNQW Sbjct: 242 EWKGQAEVNKILGNEQIIPVDGLCVRIGAMRCHSLALTIKLKRDLPLAEIESIIRAGNQW 301 Query: 301 VKWVPNDRAITVKELTPASITGSLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 360 VKWVPNDRAITVKELTPASITG LEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR Sbjct: 302 VKWVPNDRAITVKELTPASITGGLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 361 Query: 361 MLRIILG 367 MLRIILG Sbjct: 362 MLRIILG 368 >A4G4F8.1 A4G4F8_HERAR Aspartate-semialdehyde dehydrogenase EC=1.2.1.11 Length = 368 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/368 (88%), Positives = 349/368 (94%) Query: 1 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAKTATTLKDANSI 60 MK+VGLVGWRGMVGSVLMQRMQ+EGDF+HIEPVFF+TSN GGKAP+ AK TTL+DAN I Sbjct: 1 MKVVGLVGWRGMVGSVLMQRMQEEGDFEHIEPVFFTTSNKGGKAPAMAKKETTLQDANDI 60 Query: 61 DELKKCDIIITAQGGDYTTEIFPKLRAAGWNGFWIDAASTLRMKDDAVIVLDPVNDNVIR 120 D LKKCDIIIT QGGDYTTEIFPKLRAAGW+G+WIDAASTLRMKDDAVI+LDPVN NVI Sbjct: 61 DALKKCDIIITCQGGDYTTEIFPKLRAAGWDGYWIDAASTLRMKDDAVIILDPVNQNVIT 120 Query: 121 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG 180 DAL +GVKNYIGGNCTNSILLMGVGGLF+EGLVEWVSSMTYQAASGGGANHMRELL GMG Sbjct: 121 DALERGVKNYIGGNCTNSILLMGVGGLFREGLVEWVSSMTYQAASGGGANHMRELLSGMG 180 Query: 181 VISAAVTDELATPSSAILDIDRVVAKTIREDVPTEYFGAPLAGGLIPWIDAQLENGQSKE 240 V+ AV DELATP+SAILDIDR VA+TIR++VPTE+FGAPLAGGLIPWIDAQLENGQSKE Sbjct: 181 VVHGAVADELATPASAILDIDRKVAETIRKEVPTEFFGAPLAGGLIPWIDAQLENGQSKE 240 Query: 241 EWKGQAEVNKILGNDKPIPVDGLCVRIGAMRCHSLALTIKLKRDLPLSEIESIIRAGNQW 300 EWKGQAEVNKILGN K IPVDGLCVRIGAMRCHSLALTIKLKRDLPL+EIESIIR+GNQW Sbjct: 241 EWKGQAEVNKILGNAKTIPVDGLCVRIGAMRCHSLALTIKLKRDLPLAEIESIIRSGNQW 300 Query: 301 VKWVPNDRAITVKELTPASITGSLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 360 VKWVPN+RA+TVKELTPA+ITG LEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR Sbjct: 301 VKWVPNERAVTVKELTPAAITGGLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 360 Query: 361 MLRIILGK 368 MLRI+L + Sbjct: 361 MLRIVLDR 368 >A6T011.1 A6T011_JANMA Aspartate-semialdehyde dehydrogenase EC=1.2.1.11 Length = 368 Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/368 (87%), Positives = 345/368 (93%) Query: 1 MKLVGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAKTATTLKDANSI 60 MK+VGLVGWRGMVGSVLMQRMQ+EGDFDHIE VFFSTSN GGKAP AK TTL+DAN + Sbjct: 1 MKVVGLVGWRGMVGSVLMQRMQEEGDFDHIEAVFFSTSNKGGKAPVIAKKETTLQDANDL 60 Query: 61 DELKKCDIIITAQGGDYTTEIFPKLRAAGWNGFWIDAASTLRMKDDAVIVLDPVNDNVIR 120 + LKKCDIIIT QGGDYTTEIFP+LRAAGW+G+WIDAASTLRMKDDAVIVLDPVN NVI+ Sbjct: 61 EALKKCDIIITCQGGDYTTEIFPQLRAAGWDGYWIDAASTLRMKDDAVIVLDPVNQNVIK 120 Query: 121 DALAKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMG 180 DAL +GVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELL GMG Sbjct: 121 DALNRGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLSGMG 180 Query: 181 VISAAVTDELATPSSAILDIDRVVAKTIREDVPTEYFGAPLAGGLIPWIDAQLENGQSKE 240 V+ AV +ELATPSSAILDIDR VA+ IR+DVPTE+FGAPLAGGLIPWIDAQLENGQSKE Sbjct: 181 VVHGAVANELATPSSAILDIDRKVAEAIRKDVPTEFFGAPLAGGLIPWIDAQLENGQSKE 240 Query: 241 EWKGQAEVNKILGNDKPIPVDGLCVRIGAMRCHSLALTIKLKRDLPLSEIESIIRAGNQW 300 EWKGQAEVNKILGN + IPVDGLCVRIGAMRCHSLALTIKLKRDLPL+EIE+IIR+ N W Sbjct: 241 EWKGQAEVNKILGNTQIIPVDGLCVRIGAMRCHSLALTIKLKRDLPLAEIETIIRSANPW 300 Query: 301 VKWVPNDRAITVKELTPASITGSLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 360 VKWV N+RA+TV+ELTPA+ITG LEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR Sbjct: 301 VKWVANERAVTVQELTPAAITGGLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRR 360 Query: 361 MLRIILGK 368 MLRIILGK Sbjct: 361 MLRIILGK 368 >D8NAQ8.1 D8NAQ8_RALSO Aspartate-semialdehyde dehydrogenase EC=1.2.1.11 Length = 367 Score = 637 bits (1642), Expect = e-180, Method: Compositional matrix adjust. Identities = 308/365 (84%), Positives = 335/365 (91%) Query: 4 VGLVGWRGMVGSVLMQRMQDEGDFDHIEPVFFSTSNAGGKAPSFAKTATTLKDANSIDEL 63 VGLVGWRGMVGSVLMQRMQ+E DFD ++ VFFSTSNAGGKAPSFAKT L DAN ID L Sbjct: 3 VGLVGWRGMVGSVLMQRMQEEKDFDLVDTVFFSTSNAGGKAPSFAKTDAPLADANDIDAL 62 Query: 64 KKCDIIITAQGGDYTTEIFPKLRAAGWNGFWIDAASTLRMKDDAVIVLDPVNDNVIRDAL 123 K+CD IIT QGGDYTTEIFPKLRAAGWNG+WIDAASTLRM+DDAVIVLDPVN +I+DA+ Sbjct: 63 KQCDTIITCQGGDYTTEIFPKLRAAGWNGYWIDAASTLRMEDDAVIVLDPVNLQLIKDAV 122 Query: 124 AKGVKNYIGGNCTNSILLMGVGGLFKEGLVEWVSSMTYQAASGGGANHMRELLKGMGVIS 183 A+G KN+IGGNCTNSILLMGVGGLF++GLVEWVSSMTYQAASGGGANHMRELLKGMGVI Sbjct: 123 ARGTKNFIGGNCTNSILLMGVGGLFRDGLVEWVSSMTYQAASGGGANHMRELLKGMGVIH 182 Query: 184 AAVTDELATPSSAILDIDRVVAKTIREDVPTEYFGAPLAGGLIPWIDAQLENGQSKEEWK 243 V +ELA+P+SAIL+IDR VAKTIREDVPTEYF APLAGGLIPWID QL+NGQSKEEWK Sbjct: 183 REVEEELASPASAILEIDRKVAKTIREDVPTEYFPAPLAGGLIPWIDKQLDNGQSKEEWK 242 Query: 244 GQAEVNKILGNDKPIPVDGLCVRIGAMRCHSLALTIKLKRDLPLSEIESIIRAGNQWVKW 303 GQAEVNKILG D+ IPVDGLCVRIGAMRCHSL LT+KLKRDLPL EIESIIR+GN WVKW Sbjct: 243 GQAEVNKILGTDRTIPVDGLCVRIGAMRCHSLGLTLKLKRDLPLEEIESIIRSGNPWVKW 302 Query: 304 VPNDRAITVKELTPASITGSLEIGVGRVRKLNQGPEYISAFVIGDQLLWGAAEPLRRMLR 363 VPN+R IT +ELTPA+ITG L+IGVGRVRKLN GPEY+SAFVIGDQLLWGAAEPLRRMLR Sbjct: 303 VPNERGITEQELTPAAITGGLDIGVGRVRKLNMGPEYVSAFVIGDQLLWGAAEPLRRMLR 362 Query: 364 IILGK 368 I+LGK Sbjct: 363 ILLGK 367