BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0002.p (329 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B9XHE7.1 B9XHE7_9BACT Aldo/keto reductase 437 e-120 B2IZF6.1 B2IZF6_NOSP7 Aldo/keto reductase EC=1.1.1.91 420 e-115 C5CXJ2.1 C5CXJ2_VARPS Aldo/keto reductase 415 e-114 A1TRJ5.1 A1TRJ5_ACIAC Aldo/keto reductase 415 e-114 F0QC90.1 F0QC90_ACIAP NADP-dependent oxidoreductase domain protein 415 e-114 >B9XHE7.1 B9XHE7_9BACT Aldo/keto reductase Length = 315 Score = 437 bits (1123), Expect = e-120, Method: Compositional matrix adjust. Identities = 210/315 (66%), Positives = 252/315 (80%) Query: 14 LEYRKLGNSAIEVAPLAFGGNVFGWTADEATSFSLLDKFVDAGLNLVDTADVYSRWASGN 73 + RKLGNS +EVAPLA G NVFGWT DE T+F +LD FV AGLNL+DTADVYSRWA GN Sbjct: 1 MNKRKLGNSGLEVAPLALGTNVFGWTIDEPTAFKILDAFVAAGLNLLDTADVYSRWAPGN 60 Query: 74 KGGESETIIGKWIRQGGRRDKLVIATKVGMDMGDGKVGLSPAYIRRAVEDSLTRLQTDYI 133 KGGESETIIG W+++ G R ++IATKVGM+M K GLS A+I RA EDSL RLQTD+I Sbjct: 61 KGGESETIIGNWLKRTGNRSNVIIATKVGMEMAPDKKGLSKAHILRAAEDSLKRLQTDHI 120 Query: 134 DLYQSHTDDKNTPQEETLHTYGELVQQGKVRLIGASNFGAGRLEEARKLSREHGYPLYQT 193 DLYQ+H DD NTP EETL + +L++QGKV+ IGASN+ RL +A ++S++ P Y++ Sbjct: 121 DLYQAHQDDPNTPLEETLEAFAQLIKQGKVKAIGASNYTGVRLSQALQVSKQLNLPRYES 180 Query: 194 LQPEYNLYSRADFENNLEQYCLKEKIGVINYYSLASGFLSGKYRSEKDLGKSTRGGKTQS 253 LQP YNLY RA+FE +LE CL+ +GVI YYSLASGFL+GKYRS+KDL KS RG K + Sbjct: 181 LQPLYNLYDRAEFEKDLEPVCLQNHLGVICYYSLASGFLTGKYRSQKDLAKSPRGAKAAT 240 Query: 254 YLNPRGLRILDALDAVAERYGSTPAAVALAWLIARPSITAPIASATTLEQMDALIAATRL 313 YLN RGLRIL ALD V++R+ STPA VALAWLIARPS+TAPIASAT+LEQ+D LIAAT+L Sbjct: 241 YLNDRGLRILKALDEVSQRFNSTPARVALAWLIARPSVTAPIASATSLEQLDDLIAATKL 300 Query: 314 SLDAAAIARLDQASA 328 LD AAI L+QASA Sbjct: 301 QLDQAAIQLLNQASA 315 >B2IZF6.1 B2IZF6_NOSP7 Aldo/keto reductase EC=1.1.1.91 Length = 321 Score = 420 bits (1079), Expect = e-115, Method: Compositional matrix adjust. Identities = 199/312 (63%), Positives = 246/312 (78%) Query: 17 RKLGNSAIEVAPLAFGGNVFGWTADEATSFSLLDKFVDAGLNLVDTADVYSRWASGNKGG 76 RKLG S +EV+P++FGGNVFGWT DE +SF +LD F++AG N +DTADVYS+W GN+GG Sbjct: 7 RKLGRSELEVSPISFGGNVFGWTIDENSSFEILDSFIEAGGNFIDTADVYSKWVPGNQGG 66 Query: 77 ESETIIGKWIRQGGRRDKLVIATKVGMDMGDGKVGLSPAYIRRAVEDSLTRLQTDYIDLY 136 ESETI+GKW++Q G RD++VIATKVG DM GLS +I++AVEDSL RLQTDYIDLY Sbjct: 67 ESETILGKWLKQRGNRDQVVIATKVGNDMDVRGQGLSREHIQQAVEDSLQRLQTDYIDLY 126 Query: 137 QSHTDDKNTPQEETLHTYGELVQQGKVRLIGASNFGAGRLEEARKLSREHGYPLYQTLQP 196 QSH DD+NTP EETL TY EL++QGKVR IGASN+ A RL +A ++SR+HGYP Y++LQP Sbjct: 127 QSHIDDENTPLEETLETYAELIRQGKVRAIGASNYSAERLGQALEISRQHGYPRYESLQP 186 Query: 197 EYNLYSRADFENNLEQYCLKEKIGVINYYSLASGFLSGKYRSEKDLGKSTRGGKTQSYLN 256 YNLY R +E +L+Q C +++IGVINY SL SGFLSGKYRSEKDL S RG + YLN Sbjct: 187 RYNLYDRDGYEQDLQQICQEQEIGVINYSSLCSGFLSGKYRSEKDLSISLRGNSVKRYLN 246 Query: 257 PRGLRILDALDAVAERYGSTPAAVALAWLIARPSITAPIASATTLEQMDALIAATRLSLD 316 PRGL+IL+A+D VA Y TP V+LAWLIA PSITAPI SAT +EQ++ +I A + LD Sbjct: 247 PRGLQILEAIDRVATTYNFTPTQVSLAWLIANPSITAPIVSATKVEQLNDIIKAVNIKLD 306 Query: 317 AAAIARLDQASA 328 AI L+QAS+ Sbjct: 307 QDAIDLLNQASS 318 >C5CXJ2.1 C5CXJ2_VARPS Aldo/keto reductase Length = 322 Score = 415 bits (1067), Expect = e-114, Method: Compositional matrix adjust. Identities = 200/315 (63%), Positives = 246/315 (78%), Gaps = 1/315 (0%) Query: 15 EYRKLGNSAIEVAPLAFGGNVFGWTADEATSFSLLDKFVDAGLNLVDTADVYSRWASGNK 74 + R LG S + V+PLAFGGNVFGWTADEATSF LLD +VDAG N +DTADVYS W G+ Sbjct: 3 QLRSLGRSGLLVSPLAFGGNVFGWTADEATSFRLLDAWVDAGFNFIDTADVYSAWVPGHT 62 Query: 75 GGESETIIGKWIRQGGRRDKLVIATKVGMDMGDGKVGLSPAYIRRAVEDSLTRLQTDYID 134 GGESETIIGKW++Q G+R+++V+ATKVG MG+GK GLSPAYIR AVE SL RLQTD+ID Sbjct: 63 GGESETIIGKWLKQSGKRNRVVLATKVGKPMGEGKSGLSPAYIREAVEASLKRLQTDFID 122 Query: 135 LYQSHTDDKNTPQEETLHTYGELVQQGKVRLIGASNFGAGRLEEARKLSREHGYPLYQTL 194 LYQSH DD TP E++L + EL++ GKVR IGASN+ A RL EA +S G Y++L Sbjct: 123 LYQSHDDDAATPLEDSLQAFDELIKAGKVRAIGASNYSAPRLAEALDVSERLGIARYESL 182 Query: 195 QPEYNLYSRADFENNLEQYCLKEKIGVINYYSLASGFLSGKYRSEKDLGKSTRGGKT-QS 253 QP YNLY RA FE+ LE CLK ++GVIN+Y+LA+GFL+GKYR+E D KS RG T + Sbjct: 183 QPLYNLYDRAVFEDELEPLCLKREVGVINFYALAAGFLTGKYRTEADAAKSARGATTIKK 242 Query: 254 YLNPRGLRILDALDAVAERYGSTPAAVALAWLIARPSITAPIASATTLEQMDALIAATRL 313 YLNPRGLRIL+ALD VA++Y + P VA+AW IARPS+TAPIASAT++ Q++ L+ AT+L Sbjct: 243 YLNPRGLRILEALDKVAQQYNAKPGQVAIAWQIARPSVTAPIASATSIAQLEELVVATQL 302 Query: 314 SLDAAAIARLDQASA 328 LDA I LD+ASA Sbjct: 303 KLDAGTIQMLDRASA 317 >A1TRJ5.1 A1TRJ5_ACIAC Aldo/keto reductase Length = 325 Score = 415 bits (1067), Expect = e-114, Method: Compositional matrix adjust. Identities = 198/315 (62%), Positives = 247/315 (78%), Gaps = 1/315 (0%) Query: 14 LEYRKLGNSAIEVAPLAFGGNVFGWTADEATSFSLLDKFVDAGLNLVDTADVYSRWASGN 73 ++ R LG S ++V+PL FGGNVFGWT DE T+FSL+D ++DAG N +DTADVYSRW G+ Sbjct: 1 MQSRPLGRSGLQVSPLCFGGNVFGWTVDEPTTFSLIDAWLDAGFNFIDTADVYSRWNPGH 60 Query: 74 KGGESETIIGKWIRQGGRRDKLVIATKVGMDMGDGKVGLSPAYIRRAVEDSLTRLQTDYI 133 GGESE +IG+W+++ G+RD++V+ATKVG DMGDG+VGL P YIRRAVEDSL RL TDYI Sbjct: 61 MGGESEALIGQWLKRTGKRDRIVLATKVGKDMGDGRVGLKPDYIRRAVEDSLRRLHTDYI 120 Query: 134 DLYQSHTDDKNTPQEETLHTYGELVQQGKVRLIGASNFGAGRLEEARKLSREHGYPLYQT 193 DLYQSH DD +TP E+TL TY +L+++GKVR IGASN A RL EA S G P Y++ Sbjct: 121 DLYQSHDDDPSTPLEDTLGTYADLIREGKVRAIGASNHTAARLSEALATSARLGLPRYES 180 Query: 194 LQPEYNLYSRADFENNLEQYCLKEKIGVINYYSLASGFLSGKYRSEKDLGKSTRGGKT-Q 252 LQP YNLY RA FE+ L+ CL++++GVIN+Y+LA+GFL+GKYRSE D KS RG KT + Sbjct: 181 LQPLYNLYDRAVFEDELQPLCLEQQVGVINFYALAAGFLTGKYRSEADASKSARGAKTVE 240 Query: 253 SYLNPRGLRILDALDAVAERYGSTPAAVALAWLIARPSITAPIASATTLEQMDALIAATR 312 YLNPRGLRIL LD VAERY +TP VA+AW +A+P+ITAPIASAT+LEQ+ L+ A Sbjct: 241 KYLNPRGLRILAELDEVAERYEATPGQVAIAWQMAQPAITAPIASATSLEQLQDLVRAAH 300 Query: 313 LSLDAAAIARLDQAS 327 L LDA A+ L QAS Sbjct: 301 LQLDADALEALSQAS 315 >F0QC90.1 F0QC90_ACIAP NADP-dependent oxidoreductase domain protein Length = 322 Score = 415 bits (1066), Expect = e-114, Method: Compositional matrix adjust. Identities = 198/315 (62%), Positives = 246/315 (78%), Gaps = 1/315 (0%) Query: 14 LEYRKLGNSAIEVAPLAFGGNVFGWTADEATSFSLLDKFVDAGLNLVDTADVYSRWASGN 73 ++ R LG S ++V+PL FGGNVFGWT DE T+FSL+D ++DAG N +DTADVYSRW G+ Sbjct: 1 MQSRPLGRSGLQVSPLCFGGNVFGWTVDEPTTFSLIDAWLDAGFNFIDTADVYSRWNPGH 60 Query: 74 KGGESETIIGKWIRQGGRRDKLVIATKVGMDMGDGKVGLSPAYIRRAVEDSLTRLQTDYI 133 GGESE +IG+W+++ G+RD++V+ATKVG DMGDGKVGL P YIRRAVEDSL RL TDYI Sbjct: 61 MGGESEALIGQWLKRTGKRDRIVLATKVGKDMGDGKVGLKPDYIRRAVEDSLRRLHTDYI 120 Query: 134 DLYQSHTDDKNTPQEETLHTYGELVQQGKVRLIGASNFGAGRLEEARKLSREHGYPLYQT 193 DLYQSH DD +TP E+TL TY +L+++GKVR IGASN A RL EA S G P Y++ Sbjct: 121 DLYQSHDDDPSTPLEDTLGTYADLIREGKVRAIGASNHTAARLSEALATSARLGLPRYES 180 Query: 194 LQPEYNLYSRADFENNLEQYCLKEKIGVINYYSLASGFLSGKYRSEKDLGKSTRGGKT-Q 252 LQP YNLY RA FE L+ CL++++GVIN+Y+LA+GFL+GKYRSE D KS RG +T + Sbjct: 181 LQPLYNLYDRAVFEEELQPLCLEQQVGVINFYALAAGFLTGKYRSEADASKSARGARTVE 240 Query: 253 SYLNPRGLRILDALDAVAERYGSTPAAVALAWLIARPSITAPIASATTLEQMDALIAATR 312 YLNPRGLRIL LD VAERY +TP VA+AW +A+P+ITAPIASAT+LEQ+ L+ A Sbjct: 241 KYLNPRGLRILAELDEVAERYEATPGQVAIAWQMAQPAITAPIASATSLEQLQDLVRAAH 300 Query: 313 LSLDAAAIARLDQAS 327 L LDA A+ L QAS Sbjct: 301 LQLDADALEALSQAS 315