BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0042.p (329 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IZX4.1 D8IZX4_HERSS Malate dehydrogenase EC=1.1.1.37 628 e-178 A2RQ44.1 A2RQ44_HERSE Malate dehydrogenase EC=1.1.1.37 628 e-178 A6SY47.1 MDH_JANMA Malate dehydrogenase EC=1.1.1.37 600 e-170 F1VWI0.1 F1VWI0_9BURK Malate dehydrogenase 599 e-169 A4G5Z9.1 MDH_HERAR Malate dehydrogenase EC=1.1.1.37 598 e-169 >D8IZX4.1 D8IZX4_HERSS Malate dehydrogenase EC=1.1.1.37 Length = 329 Score = 628 bits (1619), Expect = e-178, Method: Compositional matrix adjust. Identities = 314/329 (95%), Positives = 322/329 (97%) Query: 1 MAKAPKRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI 60 MAKAP RVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI Sbjct: 1 MAKAPMRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI 60 Query: 61 DDCAFPLLAGVTAHSDPLTAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 DDCAFPLLAGVTAHSDP+TAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD Sbjct: 61 DDCAFPLLAGVTAHSDPMTAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 Query: 121 AVASRDVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIGQPVSA 180 AVASR+VKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIG+PVSA Sbjct: 121 AVASRNVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIGKPVSA 180 Query: 181 IEKLCVWGNHSPTMYADYRFATANGKAVKDLINDQVWNKDTFLPTVGKRGAAIIEARGLS 240 IEKLCVWGNHSPTMYADYRFATA+G +VKD INDQ WNK+ FLPTVGKRGAAIIEARGLS Sbjct: 181 IEKLCVWGNHSPTMYADYRFATADGVSVKDTINDQEWNKNVFLPTVGKRGAAIIEARGLS 240 Query: 241 SAASAANAAIDHVHDWILGTNGKWTTMGVPSDGSYGIPEGTMFGFPVTTENGEYKIVQGL 300 SAASAANAAIDHV DW+LGTNGKWTTMG+PSDGSYGIPEGTMFGFPVTTENGEYKIVQGL Sbjct: 241 SAASAANAAIDHVRDWVLGTNGKWTTMGIPSDGSYGIPEGTMFGFPVTTENGEYKIVQGL 300 Query: 301 EIDEFSQERINITLKELSEEREGVKHLVG 329 EIDEFSQERINITLKEL EEREGVKHLVG Sbjct: 301 EIDEFSQERINITLKELMEEREGVKHLVG 329 >A2RQ44.1 A2RQ44_HERSE Malate dehydrogenase EC=1.1.1.37 Length = 329 Score = 628 bits (1619), Expect = e-178, Method: Compositional matrix adjust. Identities = 314/329 (95%), Positives = 322/329 (97%) Query: 1 MAKAPKRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI 60 MAKAP RVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI Sbjct: 1 MAKAPMRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI 60 Query: 61 DDCAFPLLAGVTAHSDPLTAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 DDCAFPLLAGVTAHSDP+TAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD Sbjct: 61 DDCAFPLLAGVTAHSDPMTAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 Query: 121 AVASRDVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIGQPVSA 180 AVASR+VKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIG+PVSA Sbjct: 121 AVASRNVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIGKPVSA 180 Query: 181 IEKLCVWGNHSPTMYADYRFATANGKAVKDLINDQVWNKDTFLPTVGKRGAAIIEARGLS 240 IEKLCVWGNHSPTMYADYRFATA+G +VKD INDQ WNK+ FLPTVGKRGAAIIEARGLS Sbjct: 181 IEKLCVWGNHSPTMYADYRFATADGVSVKDTINDQEWNKNVFLPTVGKRGAAIIEARGLS 240 Query: 241 SAASAANAAIDHVHDWILGTNGKWTTMGVPSDGSYGIPEGTMFGFPVTTENGEYKIVQGL 300 SAASAANAAIDHV DW+LGTNGKWTTMG+PSDGSYGIPEGTMFGFPVTTENGEYKIVQGL Sbjct: 241 SAASAANAAIDHVRDWVLGTNGKWTTMGIPSDGSYGIPEGTMFGFPVTTENGEYKIVQGL 300 Query: 301 EIDEFSQERINITLKELSEEREGVKHLVG 329 EIDEFSQERINITLKEL EEREGVKHLVG Sbjct: 301 EIDEFSQERINITLKELMEEREGVKHLVG 329 >A6SY47.1 MDH_JANMA Malate dehydrogenase EC=1.1.1.37 Length = 329 Score = 600 bits (1548), Expect = e-170, Method: Compositional matrix adjust. Identities = 297/329 (90%), Positives = 316/329 (96%) Query: 1 MAKAPKRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI 60 MAKAP RVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEI DEKAQKALKGVIMEI Sbjct: 1 MAKAPMRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIADEKAQKALKGVIMEI 60 Query: 61 DDCAFPLLAGVTAHSDPLTAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 DDCAFPLLAGVTAHSDP+TAFKDAD+ALLVGARPRGPGMERKDLLEANAQIFTVQGKALD Sbjct: 61 DDCAFPLLAGVTAHSDPMTAFKDADVALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 Query: 121 AVASRDVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIGQPVSA 180 AVASR+VKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQ+AAKI +PV++ Sbjct: 121 AVASRNVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQIAAKISKPVTS 180 Query: 181 IEKLCVWGNHSPTMYADYRFATANGKAVKDLINDQVWNKDTFLPTVGKRGAAIIEARGLS 240 IEKL VWGNHSPTMY DYRFATA+GK+VK+ IND+VWNKD FLPTVGKRGAAII+ARG+S Sbjct: 181 IEKLTVWGNHSPTMYPDYRFATADGKSVKEAINDEVWNKDVFLPTVGKRGAAIIDARGVS 240 Query: 241 SAASAANAAIDHVHDWILGTNGKWTTMGVPSDGSYGIPEGTMFGFPVTTENGEYKIVQGL 300 SAASAANAAIDHV DW+LGTNGKW TMG+PSDGSYGIP+ T+FGFPVT ENGEYKIVQGL Sbjct: 241 SAASAANAAIDHVRDWVLGTNGKWVTMGIPSDGSYGIPKDTIFGFPVTVENGEYKIVQGL 300 Query: 301 EIDEFSQERINITLKELSEEREGVKHLVG 329 EID FSQERIN+TLKEL EEREGVKHL+G Sbjct: 301 EIDAFSQERINLTLKELLEEREGVKHLLG 329 >F1VWI0.1 F1VWI0_9BURK Malate dehydrogenase Length = 375 Score = 599 bits (1544), Expect = e-169, Method: Compositional matrix adjust. Identities = 295/329 (89%), Positives = 315/329 (95%) Query: 1 MAKAPKRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI 60 MAKAP RVAVTGAAGQIGYSLLFRIANGD+LGKDQPVILQLLEIPDEKAQKALKGV+MEI Sbjct: 47 MAKAPMRVAVTGAAGQIGYSLLFRIANGDMLGKDQPVILQLLEIPDEKAQKALKGVMMEI 106 Query: 61 DDCAFPLLAGVTAHSDPLTAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 DDCAFPLLAG++AHSDP+TAFKD D+ALLVGARPRGPGMERKDLLEANAQIFTVQGKALD Sbjct: 107 DDCAFPLLAGMSAHSDPMTAFKDIDVALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 166 Query: 121 AVASRDVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIGQPVSA 180 AVASR+VKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQ+AAK G+PV++ Sbjct: 167 AVASRNVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQIAAKTGKPVAS 226 Query: 181 IEKLCVWGNHSPTMYADYRFATANGKAVKDLINDQVWNKDTFLPTVGKRGAAIIEARGLS 240 IEKLCVWGNHSPTMYADYRFAT +G++VKD+IND WNKDTFLPTVGKRG AIIEARGLS Sbjct: 227 IEKLCVWGNHSPTMYADYRFATIDGQSVKDMINDAAWNKDTFLPTVGKRGGAIIEARGLS 286 Query: 241 SAASAANAAIDHVHDWILGTNGKWTTMGVPSDGSYGIPEGTMFGFPVTTENGEYKIVQGL 300 SAASAANAAIDHVHDW+LGT GKWTTMG+ SDGSY IPEGT+FGFPVTTENGEYKIV GL Sbjct: 287 SAASAANAAIDHVHDWVLGTGGKWTTMGIASDGSYDIPEGTIFGFPVTTENGEYKIVAGL 346 Query: 301 EIDEFSQERINITLKELSEEREGVKHLVG 329 IDEFS+ERIN+TL EL EEREGVKHLVG Sbjct: 347 AIDEFSRERINVTLNELLEEREGVKHLVG 375 >A4G5Z9.1 MDH_HERAR Malate dehydrogenase EC=1.1.1.37 Length = 329 Score = 598 bits (1543), Expect = e-169, Method: Compositional matrix adjust. Identities = 297/328 (90%), Positives = 314/328 (95%) Query: 1 MAKAPKRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIPDEKAQKALKGVIMEI 60 MAKAP RVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEI +EKAQ ALKGVIMEI Sbjct: 1 MAKAPMRVAVTGAAGQIGYSLLFRIANGDLLGKDQPVILQLLEIDNEKAQNALKGVIMEI 60 Query: 61 DDCAFPLLAGVTAHSDPLTAFKDADIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 DDCAFPLLAGV+AHSDP+TAFKD DIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD Sbjct: 61 DDCAFPLLAGVSAHSDPMTAFKDVDIALLVGARPRGPGMERKDLLEANAQIFTVQGKALD 120 Query: 121 AVASRDVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQVAAKIGQPVSA 180 AVASR+VKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQ+AAK G+PV+A Sbjct: 121 AVASRNVKVLVVGNPANTNAYIAMKSAPNLPAKNFTAMLRLDHNRALSQIAAKTGKPVTA 180 Query: 181 IEKLCVWGNHSPTMYADYRFATANGKAVKDLINDQVWNKDTFLPTVGKRGAAIIEARGLS 240 IEKL VWGNHSPTMY DYRFAT +GK+VK+ IND+VWNKD FLPTVGKRGAAIIEARG+S Sbjct: 181 IEKLTVWGNHSPTMYPDYRFATIDGKSVKEAINDEVWNKDVFLPTVGKRGAAIIEARGVS 240 Query: 241 SAASAANAAIDHVHDWILGTNGKWTTMGVPSDGSYGIPEGTMFGFPVTTENGEYKIVQGL 300 SAASAANAAIDHV DW+LGTNGKW TMG+PSDGSYGIP+ TMFGFPVTTENGEYKIVQGL Sbjct: 241 SAASAANAAIDHVRDWVLGTNGKWVTMGIPSDGSYGIPKDTMFGFPVTTENGEYKIVQGL 300 Query: 301 EIDEFSQERINITLKELSEEREGVKHLV 328 EID FSQERIN+TLKELSEEREGVKHL+ Sbjct: 301 EIDAFSQERINLTLKELSEEREGVKHLL 328