BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0024.0012.p         (178 letters)

Database: pfamseq 
           15,929,002 sequences; 5,169,768,107 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D8J0D5.1 D8J0D5_HERSS Pseudouridine synthase EC=5.4.99.-              204   4e-51
A6SXT6.1 A6SXT6_JANMA Pseudouridine synthase EC=5.4.99.-              200   9e-50
A4G6D9.1 A4G6D9_HERAR Pseudouridine synthase EC=5.4.99.-              199   1e-49
F1VVL4.1 F1VVL4_9BURK Ribosomal large subunit pseudouridine synt...   186   1e-45
C3X4X7.1 C3X4X7_OXAFO Pseudouridine synthase EC=5.4.99.-              165   2e-39

>D8J0D5.1 D8J0D5_HERSS Pseudouridine synthase EC=5.4.99.-
          Length = 370

 Score =  204 bits (519), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 103/167 (61%), Positives = 125/167 (74%), Gaps = 1/167 (0%)

Query: 1   MSRTTPPKVVKAFATEPVEIPEGDDSLDEVVE-EFTDGAEPITLKLTDDACGVRLDKVLS 59
           MSR  P ++         ++P+ DD  D     E   G EP+TL+L D+  G RLDKVLS
Sbjct: 1   MSRKKPLQITNGDTPVHTDLPQADDFDDAHDGDEIGPGLEPLTLRLDDEVIGQRLDKVLS 60

Query: 60  GLVPQYSRSRIQQWIEGGYVTVDGNPARTKMTVLGDELVIITPQAAPEDNAFQPEPMDLS 119
           GL+P++SRSRIQQWIE G+VTV+G PA+ KMT+LGDELV + PQ+ P D  + PEPM L 
Sbjct: 61  GLLPEFSRSRIQQWIEDGHVTVNGAPAKAKMTMLGDELVEVAPQSVPSDQPYGPEPMALD 120

Query: 120 ILHEDKAIMVIDKPAGLVVHPAAGNWSGTLLNGLLHHCPALAGVPRG 166
           ILHEDKA++V++KPAGLVVHPAAGNWSGTLLNGLLHHCPALA VPR 
Sbjct: 121 ILHEDKALIVLNKPAGLVVHPAAGNWSGTLLNGLLHHCPALAKVPRA 167


>A6SXT6.1 A6SXT6_JANMA Pseudouridine synthase EC=5.4.99.-
          Length = 342

 Score =  200 bits (508), Expect = 9e-50,   Method: Compositional matrix adjust.
 Identities = 98/144 (68%), Positives = 115/144 (79%), Gaps = 4/144 (2%)

Query: 22  EGDDSLDEVVEEFTDGAEPITLKLTDDACGVRLDKVLSGLVPQYSRSRIQQWIEGGYVTV 81
           EG D  D++  E      PI L L  D CGVRLDKVLS LVPQYSRSR+QQWI+GG+V+V
Sbjct: 23  EGVDDGDDLALEL----PPIELDLNPDVCGVRLDKVLSTLVPQYSRSRLQQWIDGGHVSV 78

Query: 82  DGNPARTKMTVLGDELVIITPQAAPEDNAFQPEPMDLSILHEDKAIMVIDKPAGLVVHPA 141
           DG  AR KMTV GDE V+I PQ APED AF+PE MDL+I+HED  ++VI+KPAGLVVHPA
Sbjct: 79  DGEVARAKMTVYGDEKVVIYPQPAPEDEAFKPEAMDLAIVHEDAEMLVINKPAGLVVHPA 138

Query: 142 AGNWSGTLLNGLLHHCPALAGVPR 165
           AGNWSGTLLNGLLH+ P+++GVPR
Sbjct: 139 AGNWSGTLLNGLLHYLPSISGVPR 162


>A4G6D9.1 A4G6D9_HERAR Pseudouridine synthase EC=5.4.99.-
          Length = 318

 Score =  199 bits (507), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 96/127 (75%), Positives = 107/127 (84%)

Query: 40  PITLKLTDDACGVRLDKVLSGLVPQYSRSRIQQWIEGGYVTVDGNPARTKMTVLGDELVI 99
           PI L LT   CGVRLDKVLS LVPQYSRSR+QQWI+ G+V+VDG  AR KMTV GDE V+
Sbjct: 13  PIELDLTPAVCGVRLDKVLSTLVPQYSRSRLQQWIDAGHVSVDGEIARAKMTVYGDEKVV 72

Query: 100 ITPQAAPEDNAFQPEPMDLSILHEDKAIMVIDKPAGLVVHPAAGNWSGTLLNGLLHHCPA 159
           I PQ APED AF+PE MDL+I +ED AI+VIDKPAGLVVHPAAGNWSGTLLNGLLH+ PA
Sbjct: 73  IYPQPAPEDEAFKPEAMDLNIAYEDAAILVIDKPAGLVVHPAAGNWSGTLLNGLLHYLPA 132

Query: 160 LAGVPRG 166
           +AGVPR 
Sbjct: 133 IAGVPRA 139


>F1VVL4.1 F1VVL4_9BURK Ribosomal large subunit pseudouridine synthase D
          Length = 355

 Score =  186 bits (472), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 99/167 (59%), Positives = 122/167 (73%), Gaps = 12/167 (7%)

Query: 3   RTTPPKVVKAFATEPVEIPEGDDSLDEVVEEFTDG---AEPITLKLTDDACGVRLDKVLS 59
           R TPP        +   +PE D  +DE  EE+T G     PI L LT   CG RLDKV++
Sbjct: 6   RLTPP------LNDAENLPELD--IDEQ-EEYTGGLPDMPPIELDLTPGDCGDRLDKVVA 56

Query: 60  GLVPQYSRSRIQQWIEGGYVTVDGNPARTKMTVLGDELVIITPQAAPEDNAFQPEPMDLS 119
            LVPQ+SRSR+QQWI+ G+VTVDG   RT+MTV GDE +++ PQAAPED AF PE M L+
Sbjct: 57  RLVPQFSRSRMQQWIDDGFVTVDGKVGRTRMTVYGDEHIVVLPQAAPEDTAFAPEEMALN 116

Query: 120 ILHEDKAIMVIDKPAGLVVHPAAGNWSGTLLNGLLHHCPALAGVPRG 166
           I++ED+AI+V++KPAGLVVHP +GNWSGTLLNGLLH+ PAL GVPR 
Sbjct: 117 IVYEDEAIIVVNKPAGLVVHPGSGNWSGTLLNGLLHYWPALIGVPRA 163


>C3X4X7.1 C3X4X7_OXAFO Pseudouridine synthase EC=5.4.99.-
          Length = 342

 Score =  165 bits (418), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 79/135 (58%), Positives = 98/135 (72%)

Query: 32  EEFTDGAEPITLKLTDDACGVRLDKVLSGLVPQYSRSRIQQWIEGGYVTVDGNPARTKMT 91
           EE     EP+   L+    G RLDK+++  +P YSRSRIQ+WIE GYVTVDG  A+ K T
Sbjct: 20  EEILTEPEPVRFVLSLKEGGERLDKIVARHLPDYSRSRIQRWIEQGYVTVDGKAAQGKQT 79

Query: 92  VLGDELVIITPQAAPEDNAFQPEPMDLSILHEDKAIMVIDKPAGLVVHPAAGNWSGTLLN 151
           V+GDE +++ PQ A ED AF PEP+   +L ED+ I+V++KPAGLVVHPAAGNWSGTLLN
Sbjct: 80  VVGDEEIVVLPQLAEEDLAFVPEPVGFPVLFEDRDILVVNKPAGLVVHPAAGNWSGTLLN 139

Query: 152 GLLHHCPALAGVPRG 166
           GLLHH P  A +PR 
Sbjct: 140 GLLHHLPKSAAIPRA 154