BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0006.p (386 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0E4.1 D8J0E4_HERSS Pyridoxal phosphate dependent aspartate/ty... 688 0.0 Q1LPR4.1 Q1LPR4_RALME Methionine aminotransferase, PLP-dependent... 605 e-171 A6SXS6.1 A6SXS6_JANMA AspB aspartate aminotransferase EC=2.6.1.1 598 e-169 Q0KCM6.1 Q0KCM6_CUPNH Aspartate/tyrosine/aromatic aminotransfera... 597 e-169 Q473P2.1 Q473P2_CUPPJ 2-keto-4-methylthiobutyrate aminotransfera... 595 e-168 >D8J0E4.1 D8J0E4_HERSS Pyridoxal phosphate dependent aspartate/tyrosine/aromatic aminotransferase protein EC=2.6.1.- Length = 385 Score = 688 bits (1776), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/386 (84%), Positives = 356/386 (92%), Gaps = 1/386 (0%) Query: 1 MSQPANIVSKLPRVGTTIFTVMSALASEKGAVNLGQGFPDFDCDPALVDAVTSAMKTGLN 60 MS P NIV+KLP+VGTTIFTVMSALASEKGAVNLGQGFPDF CDPALV AVT AM+ GLN Sbjct: 1 MSTP-NIVTKLPKVGTTIFTVMSALASEKGAVNLGQGFPDFHCDPALVAAVTQAMQEGLN 59 Query: 61 QYPPMAGVPLLREAIAQKIKTLHGHTYDALNEITVTAGATQGILTSILCAVHAGDEVIVI 120 QYPPMAGVP+LREAIA+K++ L+GH YD ++EITVTAGATQGILTS+LCAVH GDEVIVI Sbjct: 60 QYPPMAGVPVLREAIAEKVEKLYGHRYDPVSEITVTAGATQGILTSVLCAVHPGDEVIVI 119 Query: 121 EPAYDCYVPAIELAGGVPVFVQMTVSSDGYSVPWDKVAAAVTSKTRLIMVNTPHNPTGSI 180 EP YDCYVPAIELAGGVPVFVQM V + GYS+PWDKV AAVT KTR+IMVNTPHNPTGS+ Sbjct: 120 EPVYDCYVPAIELAGGVPVFVQMEVGAQGYSIPWDKVKAAVTPKTRMIMVNTPHNPTGSV 179 Query: 181 LKKTDINALADIVRGTDILILSDEVYEHMVYDGQAHESLCRHPELAPRTFINSSFGKTYH 240 ++ D+ ALADIVRGTDILILSDEVYEHMVYDGQ HESL RHPELA R+FINSSFGKTYH Sbjct: 180 MRAADVAALADIVRGTDILILSDEVYEHMVYDGQPHESLARHPELAERSFINSSFGKTYH 239 Query: 241 VTGWKIGFVAAPAALTAEFRKVHQFNVFTVNTPVQYGIAEYMKNPAPYVELPAFYQRKRD 300 VTGWK+G+VAAPAALTAEFRKVHQFNVFTVNTPVQYG+A YMK+PAPY++LPAFYQ KRD Sbjct: 240 VTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPVQYGLAAYMKDPAPYLDLPAFYQHKRD 299 Query: 301 LFRDGLKNTRFKLLPSDGTYFQCVEYGAISDLSEAEFSKWLTTEIGVAAIPVSAFYNTPK 360 LFR GL NTRF+LLPS GTYFQCV+YGAIS L EAEF KWLT+EIGVAAIPVSAFYNTP+ Sbjct: 300 LFRTGLANTRFELLPSQGTYFQCVKYGAISALPEAEFCKWLTSEIGVAAIPVSAFYNTPR 359 Query: 361 ESGIVRFCFAKKDETLRLALDRLAKL 386 ESGIVRFCFAKKDETL+LAL+RLAKL Sbjct: 360 ESGIVRFCFAKKDETLQLALERLAKL 385 >Q1LPR4.1 Q1LPR4_RALME Methionine aminotransferase, PLP-dependent EC=2.6.1.- Length = 389 Score = 605 bits (1560), Expect = e-171, Method: Compositional matrix adjust. Identities = 286/378 (75%), Positives = 330/378 (87%), Gaps = 2/378 (0%) Query: 9 SKLPRVGTTIFTVMSALASEKGAVNLGQGFPDFDCDPALVDAVTSAMKTGLNQYPPMAGV 68 S+LP VGTTIFTVMSALA+EK AVNLGQGFPDFDCDP +VDAVT AM+TG NQYPPMAGV Sbjct: 14 SRLPNVGTTIFTVMSALAAEKNAVNLGQGFPDFDCDPRIVDAVTHAMRTGHNQYPPMAGV 73 Query: 69 PLLREAIAQKIKTLHGHTYDALNEITVTAGATQGILTSILCAVHAGDEVIVIEPAYDCYV 128 P LR+AIA KI L+ HTYD EITVTAGATQG+LT+ILCAVH GDEVIV+EP YD Y+ Sbjct: 74 PQLRQAIAAKIAKLYEHTYDWNTEITVTAGATQGLLTAILCAVHPGDEVIVLEPCYDSYL 133 Query: 129 PAIELAGGVPVFVQMTVSSDGYSVPWDKVAAAVTSKTRLIMVNTPHNPTGSILKKTDINA 188 PAIELAG V V T+ + + +P+DK+AAA+T +TR+IM+NTPHNPTG+I ++ D+ Sbjct: 134 PAIELAGATAVPV--TLEAPLFRIPFDKLAAAITPRTRMIMINTPHNPTGTIWREEDMQQ 191 Query: 189 LADIVRGTDILILSDEVYEHMVYDGQAHESLCRHPELAPRTFINSSFGKTYHVTGWKIGF 248 LAD++ GTDIL+LSDEVYEHMVYDGQ HES+ RHPELA R+F+ SSFGKTYHVTGWK+GF Sbjct: 192 LADLLAGTDILLLSDEVYEHMVYDGQQHESVARHPELARRSFVVSSFGKTYHVTGWKVGF 251 Query: 249 VAAPAALTAEFRKVHQFNVFTVNTPVQYGIAEYMKNPAPYVELPAFYQRKRDLFRDGLKN 308 VAAPAAL+ EFRKVHQFNVFTVNTPVQYG+A+YM +PAPY+ L AFYQ KRD FR GL Sbjct: 252 VAAPAALSNEFRKVHQFNVFTVNTPVQYGLADYMADPAPYLNLSAFYQAKRDYFRAGLAG 311 Query: 309 TRFKLLPSDGTYFQCVEYGAISDLSEAEFSKWLTTEIGVAAIPVSAFYNTPKESGIVRFC 368 TRFKLLPSDGTYFQCV+Y AISD+SEA+FS WLT EIGVAAIPVSAFY+TP+ESG+VRFC Sbjct: 312 TRFKLLPSDGTYFQCVDYSAISDMSEADFSMWLTREIGVAAIPVSAFYSTPRESGVVRFC 371 Query: 369 FAKKDETLRLALDRLAKL 386 FAKK+ETL+LALDRLAKL Sbjct: 372 FAKKEETLKLALDRLAKL 389 >A6SXS6.1 A6SXS6_JANMA AspB aspartate aminotransferase EC=2.6.1.1 Length = 393 Score = 598 bits (1542), Expect = e-169, Method: Compositional matrix adjust. Identities = 282/381 (74%), Positives = 328/381 (86%) Query: 6 NIVSKLPRVGTTIFTVMSALASEKGAVNLGQGFPDFDCDPALVDAVTSAMKTGLNQYPPM 65 +I SKLP+VGTTIFT+MSALA+EK AVNLGQGFPDF+CDPAL+ AV AM++GLNQYP M Sbjct: 13 SIQSKLPQVGTTIFTLMSALAAEKKAVNLGQGFPDFECDPALITAVNDAMQSGLNQYPLM 72 Query: 66 AGVPLLREAIAQKIKTLHGHTYDALNEITVTAGATQGILTSILCAVHAGDEVIVIEPAYD 125 G P LREAIA+KI L+G+ Y NEITVTAGATQ +LT+I C + GDEVIVIEPA+D Sbjct: 73 TGAPALREAIAKKIAALYGYHYHPHNEITVTAGATQALLTAIHCCIRPGDEVIVIEPAFD 132 Query: 126 CYVPAIELAGGVPVFVQMTVSSDGYSVPWDKVAAAVTSKTRLIMVNTPHNPTGSILKKTD 185 Y+PAI LAGG V VQM + +GY VPW KVAAAV+SKTRLIM+N+PHNPTGS+L D Sbjct: 133 SYLPAIALAGGKAVCVQMELDDNGYIVPWAKVAAAVSSKTRLIMINSPHNPTGSVLLPAD 192 Query: 186 INALADIVRGTDILILSDEVYEHMVYDGQAHESLCRHPELAPRTFINSSFGKTYHVTGWK 245 + ALADIVRG+DIL+LSDEVYEHMVYDG HES+ RHPELA RTF+ SSFGKTYHVTGWK Sbjct: 193 MQALADIVRGSDILLLSDEVYEHMVYDGIPHESVSRHPELAARTFVVSSFGKTYHVTGWK 252 Query: 246 IGFVAAPAALTAEFRKVHQFNVFTVNTPVQYGIAEYMKNPAPYVELPAFYQRKRDLFRDG 305 IG+VAAPAALTAEFRKVHQ+NVF+VNTP+Q+ IA YM +P PY+ LP FYQRKRDLFRDG Sbjct: 253 IGYVAAPAALTAEFRKVHQYNVFSVNTPMQHAIAHYMADPTPYLNLPKFYQRKRDLFRDG 312 Query: 306 LKNTRFKLLPSDGTYFQCVEYGAISDLSEAEFSKWLTTEIGVAAIPVSAFYNTPKESGIV 365 LKNTRF+LLP+DGTYFQCV+Y AISDL E +F++WLTTEIGVAAIPVSAFY + K++GI+ Sbjct: 313 LKNTRFRLLPADGTYFQCVDYRAISDLPENDFAQWLTTEIGVAAIPVSAFYESAKDAGII 372 Query: 366 RFCFAKKDETLRLALDRLAKL 386 RF FAKKDETL+ AL+RL KL Sbjct: 373 RFYFAKKDETLQTALERLNKL 393 >Q0KCM6.1 Q0KCM6_CUPNH Aspartate/tyrosine/aromatic aminotransferase EC=2.6.1.- Length = 393 Score = 597 bits (1540), Expect = e-169, Method: Compositional matrix adjust. Identities = 281/378 (74%), Positives = 328/378 (86%), Gaps = 2/378 (0%) Query: 9 SKLPRVGTTIFTVMSALASEKGAVNLGQGFPDFDCDPALVDAVTSAMKTGLNQYPPMAGV 68 S+LP VGTTIFTVMSALA+EK AVNLGQGFPDFDCDP +VDAVT+AM+ G NQYPPMAGV Sbjct: 18 SRLPAVGTTIFTVMSALATEKNAVNLGQGFPDFDCDPRIVDAVTAAMRAGHNQYPPMAGV 77 Query: 69 PLLREAIAQKIKTLHGHTYDALNEITVTAGATQGILTSILCAVHAGDEVIVIEPAYDCYV 128 P LR+AIA KI +L+GH Y EITVTAGATQGILT+ILCAVH GDEVIV+EP YD Y+ Sbjct: 78 PRLRQAIAAKIASLYGHQYSWDTEITVTAGATQGILTAILCAVHPGDEVIVLEPCYDSYL 137 Query: 129 PAIELAGGVPVFVQMTVSSDGYSVPWDKVAAAVTSKTRLIMVNTPHNPTGSILKKTDINA 188 PAIELAG V V T+ + + VP+DK+AAA+T +TR+I++NTPHNPTG+IL+ D++ Sbjct: 138 PAIELAGATAVPV--TLEAPEFRVPFDKLAAAITPRTRMILINTPHNPTGTILRAADMDQ 195 Query: 189 LADIVRGTDILILSDEVYEHMVYDGQAHESLCRHPELAPRTFINSSFGKTYHVTGWKIGF 248 LA I+ GTDIL+LSDEVYEHMVYDGQ H S+ RHPELA R+F+ SSFGKTYHVTGWK+G+ Sbjct: 196 LAQILAGTDILLLSDEVYEHMVYDGQQHASVSRHPELARRSFVISSFGKTYHVTGWKVGY 255 Query: 249 VAAPAALTAEFRKVHQFNVFTVNTPVQYGIAEYMKNPAPYVELPAFYQRKRDLFRDGLKN 308 VAAPAAL AEFRKVHQFNVFTVNTPVQ+G+A+YM +PAPY++L AFYQ KRD FR GL N Sbjct: 256 VAAPAALMAEFRKVHQFNVFTVNTPVQHGLADYMADPAPYLQLSAFYQAKRDFFRAGLAN 315 Query: 309 TRFKLLPSDGTYFQCVEYGAISDLSEAEFSKWLTTEIGVAAIPVSAFYNTPKESGIVRFC 368 +RFKLLPSDGTYFQCV+Y AISDLSEA+F+ WLT EIGVAAIPVSAFY P+ESG+VRFC Sbjct: 316 SRFKLLPSDGTYFQCVDYSAISDLSEADFAMWLTREIGVAAIPVSAFYTQPRESGVVRFC 375 Query: 369 FAKKDETLRLALDRLAKL 386 FAKK+ETL LAL+RLA+L Sbjct: 376 FAKKEETLALALERLARL 393 >Q473P2.1 Q473P2_CUPPJ 2-keto-4-methylthiobutyrate aminotransferase EC=2.6.1.- Length = 390 Score = 595 bits (1535), Expect = e-168, Method: Compositional matrix adjust. Identities = 282/379 (74%), Positives = 328/379 (86%), Gaps = 2/379 (0%) Query: 8 VSKLPRVGTTIFTVMSALASEKGAVNLGQGFPDFDCDPALVDAVTSAMKTGLNQYPPMAG 67 VS+LP VGTTIFTVMSALA+EK AVNLGQGFPDFDCDP +VDAVT AM+TG NQYPPMAG Sbjct: 14 VSRLPSVGTTIFTVMSALAAEKNAVNLGQGFPDFDCDPRIVDAVTHAMRTGHNQYPPMAG 73 Query: 68 VPLLREAIAQKIKTLHGHTYDALNEITVTAGATQGILTSILCAVHAGDEVIVIEPAYDCY 127 VP LR+AIA KI TL+GH Y +EITVTAGATQGILT+ILCAVH GDEVIV+EP YD Y Sbjct: 74 VPRLRQAIADKIATLYGHRYSWESEITVTAGATQGILTAILCAVHPGDEVIVLEPCYDSY 133 Query: 128 VPAIELAGGVPVFVQMTVSSDGYSVPWDKVAAAVTSKTRLIMVNTPHNPTGSILKKTDIN 187 +PAIELAG V V T+ + + VP+D++AAA+T +TR+I++NTPHNPTG+I + D++ Sbjct: 134 LPAIELAGATAVPV--TLEAPDFRVPFDRLAAAITPRTRMILINTPHNPTGTIWRAADMD 191 Query: 188 ALADIVRGTDILILSDEVYEHMVYDGQAHESLCRHPELAPRTFINSSFGKTYHVTGWKIG 247 LA ++ GTDIL+LSDEVYEHMVYD + H S+ RHPELA R+F+ SSFGKTYHVTGWK+G Sbjct: 192 KLAQLLAGTDILLLSDEVYEHMVYDREPHASVSRHPELARRSFVISSFGKTYHVTGWKVG 251 Query: 248 FVAAPAALTAEFRKVHQFNVFTVNTPVQYGIAEYMKNPAPYVELPAFYQRKRDLFRDGLK 307 +VAAPAAL+AEFRKVHQFNVFTVNTPVQ+G+A+YM +PAPY+EL AFYQ KRD FR GL Sbjct: 252 YVAAPAALSAEFRKVHQFNVFTVNTPVQHGLADYMADPAPYLELSAFYQAKRDYFRAGLA 311 Query: 308 NTRFKLLPSDGTYFQCVEYGAISDLSEAEFSKWLTTEIGVAAIPVSAFYNTPKESGIVRF 367 NTRFKLLPS+GTYFQCV+Y AISDLSEAEFS WLT EIGVAAIPVSAFY P+ESG+VRF Sbjct: 312 NTRFKLLPSEGTYFQCVDYSAISDLSEAEFSMWLTREIGVAAIPVSAFYTQPRESGVVRF 371 Query: 368 CFAKKDETLRLALDRLAKL 386 CFAKK+ETL AL+RLAKL Sbjct: 372 CFAKKEETLSRALERLAKL 390