BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0023.0055.p (344 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRY8.1 D8IRY8_HERSS Dihydroorotase EC=3.5.2.3 622 e-176 A6SUM6.1 A6SUM6_JANMA Dihydroorotase EC=3.5.2.3 614 e-174 A4G1S1.1 A4G1S1_HERAR Dihydroorotase EC=3.5.2.3 603 e-170 B2AH54.1 PYRC_CUPTR Dihydroorotase EC=3.5.2.3 587 e-166 Q0KEE2.1 PYRC_CUPNH Dihydroorotase EC=3.5.2.3 585 e-165 >D8IRY8.1 D8IRY8_HERSS Dihydroorotase EC=3.5.2.3 Length = 344 Score = 622 bits (1604), Expect = e-176, Method: Compositional matrix adjust. Identities = 291/343 (84%), Positives = 315/343 (91%) Query: 1 MSDVVTITRPDDWHLHLRDGATMASVLPHTVHQFARAIVMPNLKPPVTTVALASAYRDRI 60 MS+V+TITRPDDWHLHLRDGATM VLPHT QFARAIVMPNLKPPVTT A A AYR+RI Sbjct: 1 MSNVLTITRPDDWHLHLRDGATMQDVLPHTARQFARAIVMPNLKPPVTTTAQAGAYRERI 60 Query: 61 LAALPAGSDFEPLMVLYLTDNTPPEEIRKAKDSGFVHAVKLYPAGATTNSDAGVTDLRNC 120 LAALP G FEPLMVLYLTDNTPP+EIR+AK+SGFV AVKLYPAGATTNSDAGVTDL C Sbjct: 61 LAALPQGMSFEPLMVLYLTDNTPPDEIRRAKESGFVKAVKLYPAGATTNSDAGVTDLSKC 120 Query: 121 YKTLEVLQETGMPFLVHGEVTDPAIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKD 180 YKTLEVLQE GMPFLVHGEVTDP ID+FDREAVFI+R+M PLR+ MPELKVVFEHITTK+ Sbjct: 121 YKTLEVLQEVGMPFLVHGEVTDPEIDLFDREAVFIERIMKPLRQAMPELKVVFEHITTKE 180 Query: 181 AADYVMSSEGPTAATITAHHLLYNRNEIFKGGIRPHYYCLPVLKRETHRQALVAAAISGS 240 AADYV++ EGPTAATITAHHLL+NRNEIFKGGIRPHYYCLPVLKRETHR+ALVAAA SG+ Sbjct: 181 AADYVLAGEGPTAATITAHHLLFNRNEIFKGGIRPHYYCLPVLKRETHRKALVAAATSGN 240 Query: 241 DKFFLGTDSAPHAKGLKEHACGCAGCYTALHALELYAQAFDQAGALDKLEAFASFNGPDF 300 +KFFLGTDSAPHAKG KEHACGCAGCYTALHALELYAQAFD AGALDK EAFASFNGPDF Sbjct: 241 NKFFLGTDSAPHAKGAKEHACGCAGCYTALHALELYAQAFDSAGALDKFEAFASFNGPDF 300 Query: 301 YDLPRNQGSVTLRRENWTIPAELPMGDTSVVPLNGGETIAWKM 343 YDLPRN G+VTL+RE W+IPAELPMG+ +VVPL+ GE + WKM Sbjct: 301 YDLPRNTGTVTLKRETWSIPAELPMGEATVVPLSAGEQMNWKM 343 >A6SUM6.1 A6SUM6_JANMA Dihydroorotase EC=3.5.2.3 Length = 352 Score = 614 bits (1583), Expect = e-174, Method: Compositional matrix adjust. Identities = 288/339 (84%), Positives = 310/339 (91%) Query: 5 VTITRPDDWHLHLRDGATMASVLPHTVHQFARAIVMPNLKPPVTTVALASAYRDRILAAL 64 +TITRPDDWHLHLRDGAT+ASVLP T QFARAIVMPNLKPPVTT A A AYRDRILAAL Sbjct: 13 ITITRPDDWHLHLRDGATIASVLPDTARQFARAIVMPNLKPPVTTTAQALAYRDRILAAL 72 Query: 65 PAGSDFEPLMVLYLTDNTPPEEIRKAKDSGFVHAVKLYPAGATTNSDAGVTDLRNCYKTL 124 PAG FEPLMVLYLTDNTPPEEI++AK+SG VHAVKLYPAGATTNSDAGV+DL CYKTL Sbjct: 73 PAGMSFEPLMVLYLTDNTPPEEIQRAKESGAVHAVKLYPAGATTNSDAGVSDLTKCYKTL 132 Query: 125 EVLQETGMPFLVHGEVTDPAIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKDAADY 184 E++Q+ GMPFLVHGEVTDPAIDIFDREAVFIDRVM PLRRDMPELKVVFEHITTKDAA Y Sbjct: 133 EMMQKVGMPFLVHGEVTDPAIDIFDREAVFIDRVMKPLRRDMPELKVVFEHITTKDAAQY 192 Query: 185 VMSSEGPTAATITAHHLLYNRNEIFKGGIRPHYYCLPVLKRETHRQALVAAAISGSDKFF 244 V ++G ATITAHHLLYNRNE+FKGGIRPHYYCLPVLKRE HRQALVAAAISGS+KFF Sbjct: 193 VAEADGHVGATITAHHLLYNRNELFKGGIRPHYYCLPVLKREIHRQALVAAAISGSNKFF 252 Query: 245 LGTDSAPHAKGLKEHACGCAGCYTALHALELYAQAFDQAGALDKLEAFASFNGPDFYDLP 304 LGTDSAPHAKGLKEHACGCAGCYTALHA+ELY QAFDQA ALDKLE FASFNGPDFY LP Sbjct: 253 LGTDSAPHAKGLKEHACGCAGCYTALHAMELYTQAFDQADALDKLEQFASFNGPDFYQLP 312 Query: 305 RNQGSVTLRRENWTIPAELPMGDTSVVPLNGGETIAWKM 343 RN G++TL+RE W IPAE+P+G+T++VPLNGGETI WK Sbjct: 313 RNTGTITLQREEWQIPAEVPLGNTTLVPLNGGETIGWKF 351 >A4G1S1.1 A4G1S1_HERAR Dihydroorotase EC=3.5.2.3 Length = 352 Score = 603 bits (1555), Expect = e-170, Method: Compositional matrix adjust. Identities = 282/339 (83%), Positives = 304/339 (89%) Query: 5 VTITRPDDWHLHLRDGATMASVLPHTVHQFARAIVMPNLKPPVTTVALASAYRDRILAAL 64 +TITRPDDWHLHLRDGAT+ASVLP T QFARAIVMPNLKPPVTT A A AYR+RILAAL Sbjct: 13 ITITRPDDWHLHLRDGATIASVLPDTARQFARAIVMPNLKPPVTTTAQAVAYRERILAAL 72 Query: 65 PAGSDFEPLMVLYLTDNTPPEEIRKAKDSGFVHAVKLYPAGATTNSDAGVTDLRNCYKTL 124 PAG FEPLM LYLT+NTPPEEI++A+DSG VHAVKLYPAGATTNSDAGV+DL CYKTL Sbjct: 73 PAGMQFEPLMTLYLTNNTPPEEIQRARDSGVVHAVKLYPAGATTNSDAGVSDLSKCYKTL 132 Query: 125 EVLQETGMPFLVHGEVTDPAIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKDAADY 184 E +Q+ GMPFLVHGEVTDP +DIFDREAVFIDRVM PLRRDMPELKVVFEHITTKDAA Y Sbjct: 133 EAMQKIGMPFLVHGEVTDPNVDIFDREAVFIDRVMQPLRRDMPELKVVFEHITTKDAAQY 192 Query: 185 VMSSEGPTAATITAHHLLYNRNEIFKGGIRPHYYCLPVLKRETHRQALVAAAISGSDKFF 244 V ++ AATITAHHLLYNRNEIFKGGIRPHYYCLPVLKRE HRQALVAAA SGS+KFF Sbjct: 193 VAEADRHVAATITAHHLLYNRNEIFKGGIRPHYYCLPVLKRELHRQALVAAATSGSNKFF 252 Query: 245 LGTDSAPHAKGLKEHACGCAGCYTALHALELYAQAFDQAGALDKLEAFASFNGPDFYDLP 304 LGTDSAPH KGLKEHACGCAGCYTALHA+ELY QAFDQA ALDKLE FASFNGPDFY LP Sbjct: 253 LGTDSAPHPKGLKEHACGCAGCYTALHAMELYTQAFDQADALDKLEQFASFNGPDFYSLP 312 Query: 305 RNQGSVTLRRENWTIPAELPMGDTSVVPLNGGETIAWKM 343 RN G++TLRRE W +P ELP+G+T++VPLNGGETI WK Sbjct: 313 RNTGTITLRREEWQVPGELPLGETTLVPLNGGETIGWKF 351 >B2AH54.1 PYRC_CUPTR Dihydroorotase EC=3.5.2.3 Length = 344 Score = 587 bits (1514), Expect = e-166, Method: Compositional matrix adjust. Identities = 277/342 (80%), Positives = 300/342 (87%) Query: 1 MSDVVTITRPDDWHLHLRDGATMASVLPHTVHQFARAIVMPNLKPPVTTVALASAYRDRI 60 M+ +TITRPDDWHLHLRDGA +A+VLP T QFARAIVMPNLKPPVTTVA A AYR RI Sbjct: 1 MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFARAIVMPNLKPPVTTVAQAQAYRARI 60 Query: 61 LAALPAGSDFEPLMVLYLTDNTPPEEIRKAKDSGFVHAVKLYPAGATTNSDAGVTDLRNC 120 LAALPAG FEPLM LYLTDNT PEEI A+ SGFVH VKLYPAGATTNSDAGVTD+R C Sbjct: 61 LAALPAGMQFEPLMTLYLTDNTGPEEIAAARASGFVHGVKLYPAGATTNSDAGVTDIRRC 120 Query: 121 YKTLEVLQETGMPFLVHGEVTDPAIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKD 180 Y LE +Q G+P LVHGEVTDPAIDIFDREAVFI+RVMTPLRRDMPELKVVFEHITTKD Sbjct: 121 YPALEAMQRAGLPLLVHGEVTDPAIDIFDREAVFIERVMTPLRRDMPELKVVFEHITTKD 180 Query: 181 AADYVMSSEGPTAATITAHHLLYNRNEIFKGGIRPHYYCLPVLKRETHRQALVAAAISGS 240 AA YV + GP ATITAHHLLYNRN IF GGIRPHYYCLPVLKRETHR+ALVAAA SGS Sbjct: 181 AAQYVRDASGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHREALVAAATSGS 240 Query: 241 DKFFLGTDSAPHAKGLKEHACGCAGCYTALHALELYAQAFDQAGALDKLEAFASFNGPDF 300 ++FFLGTDSAPHA+GLKEHACGCAGCYTALHA+ELYA+AFD AGALDKLEAFASFNGP F Sbjct: 241 ERFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFASFNGPAF 300 Query: 301 YDLPRNQGSVTLRRENWTIPAELPMGDTSVVPLNGGETIAWK 342 Y LPRN G++TL RE+W +PAELP GDT++VPL GGET+ WK Sbjct: 301 YGLPRNTGTLTLEREDWELPAELPYGDTTLVPLRGGETLRWK 342 >Q0KEE2.1 PYRC_CUPNH Dihydroorotase EC=3.5.2.3 Length = 344 Score = 585 bits (1508), Expect = e-165, Method: Compositional matrix adjust. Identities = 276/342 (80%), Positives = 300/342 (87%) Query: 1 MSDVVTITRPDDWHLHLRDGATMASVLPHTVHQFARAIVMPNLKPPVTTVALASAYRDRI 60 M+ +TITRPDDWHLHLRDGA +A+VLP T QFARAI+MPNLKPPVTTVA A AYR RI Sbjct: 1 MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFARAIIMPNLKPPVTTVAQAQAYRARI 60 Query: 61 LAALPAGSDFEPLMVLYLTDNTPPEEIRKAKDSGFVHAVKLYPAGATTNSDAGVTDLRNC 120 LAALPAG FEPLM LYLTDNT EEI AK SGFVH VKLYPAGATTNSDAGVTD+R C Sbjct: 61 LAALPAGLQFEPLMTLYLTDNTTAEEIAAAKASGFVHGVKLYPAGATTNSDAGVTDIRRC 120 Query: 121 YKTLEVLQETGMPFLVHGEVTDPAIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKD 180 Y LE +Q G+P LVHGEVTDP+IDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKD Sbjct: 121 YPALEAMQRAGLPLLVHGEVTDPSIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKD 180 Query: 181 AADYVMSSEGPTAATITAHHLLYNRNEIFKGGIRPHYYCLPVLKRETHRQALVAAAISGS 240 AA+YV + GP ATITAHHLLYNRN IF GGIRPHYYCLPVLKRETHR+ALVAAA+SGS Sbjct: 181 AAEYVRDASGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHREALVAAAVSGS 240 Query: 241 DKFFLGTDSAPHAKGLKEHACGCAGCYTALHALELYAQAFDQAGALDKLEAFASFNGPDF 300 +FFLGTDSAPHA+GLKEHACGCAGCYTALHA+ELYA+AFD AGALDKLEAFASFNGP F Sbjct: 241 PRFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFASFNGPAF 300 Query: 301 YDLPRNQGSVTLRRENWTIPAELPMGDTSVVPLNGGETIAWK 342 Y LPRN G++TL RE+W +PAELP GDT++VPL GGET+ WK Sbjct: 301 YGLPRNTGTLTLEREDWELPAELPYGDTTLVPLRGGETLRWK 342