BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0023.0012.p (364 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRV6.1 D8IRV6_HERSS Long-chain-fatty-acid-CoA ligase protein E... 389 e-106 E1THZ4.1 E1THZ4_BURSG AMP-dependent synthetase and ligase 306 4e-81 B1Y4S3.1 B1Y4S3_LEPCP AMP-dependent synthetase and ligase 262 8e-68 B2JSJ9.1 B2JSJ9_BURP8 AMP-dependent synthetase and ligase 261 1e-67 C5CZF6.1 C5CZF6_VARPS AMP-dependent synthetase and ligase 255 6e-66 >D8IRV6.1 D8IRV6_HERSS Long-chain-fatty-acid-CoA ligase protein EC=6.2.1.3 Length = 556 Score = 389 bits (998), Expect = e-106, Method: Compositional matrix adjust. Identities = 189/236 (80%), Positives = 206/236 (87%), Gaps = 2/236 (0%) Query: 1 MNLGRLLSDVARRFPDEPGLIFGDGTADGKGDKIATWKQINDRVDTLAHSLQKLGVSKGD 60 MNLGRLLSDVARRFPDEPGLI G ADG D++ W++IN RVD LAH+L + GV KGD Sbjct: 30 MNLGRLLSDVARRFPDEPGLILAQGAADGS-DRLIPWREINARVDALAHALTRRGVKKGD 88 Query: 61 KMLVHSRNNLQIFESAWAAFKLGMVWVPTNVRITPPEAAYLGQSSGASVMLYDRGFANYV 120 KMLVHSRNN QIFESAWAAFK+G+VWVPTN RITPPEAAYLGQSSGA VMLYDRGFA YV Sbjct: 89 KMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSSGACVMLYDRGFAQYV 148 Query: 121 DAVKEVSPALKHVIALQDPRAGELDFETLATATGAHQSFDEVEVDYEDPLWFFYTSGTTG 180 DAVK SPAL+HV+AL D RAGELD+E L G+ +F E EVDY+DPLWFFYTSGTTG Sbjct: 149 DAVKAASPALEHVVALADARAGELDYEALVR-EGSGAAFREAEVDYDDPLWFFYTSGTTG 207 Query: 181 HPKAGMLSHGQMAFVVTNHLADLLPGLTHQSRSLVVAPLSHGAGIHAVVNTARGAA 236 HPKAGMLSHGQMAFVVTNHLADL+PGLTHQSRSLVVAPLSHGAG+HAV+NTARGAA Sbjct: 208 HPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAVINTARGAA 263 >E1THZ4.1 E1THZ4_BURSG AMP-dependent synthetase and ligase Length = 525 Score = 306 bits (783), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 151/236 (63%), Positives = 182/236 (77%), Gaps = 9/236 (3%) Query: 1 MNLGRLLSDVARRFPDEPGLIFGDGTADGKGDKIATWKQINDRVDTLAHSLQKLGVSKGD 60 MNLG LL+D ARR D+PG I + +W++IN RVD++AH L +LGV KGD Sbjct: 6 MNLGNLLTDAARRHADQPGFI--------HAGRSMSWQEINTRVDSVAHGLSRLGVGKGD 57 Query: 61 KMLVHSRNNLQIFESAWAAFKLGMVWVPTNVRITPPEAAYLGQSSGASVMLYDRGFANYV 120 ++LVHSRNN+ +FESAW AFKLG VWVPTN RIT EAAYLG+SSGA VM+Y+ GF +V Sbjct: 58 RILVHSRNNIALFESAWVAFKLGAVWVPTNCRITATEAAYLGESSGAKVMIYEAGFDAHV 117 Query: 121 DAVKEVSPALKHVIALQDPRAGELDFETLATATGAHQSFDEVEVDYEDPLWFFYTSGTTG 180 DAV+ S ALKHV+A+ R GEL++E LA A F +VD +DPLWFFYTSGTTG Sbjct: 118 DAVRAASAALKHVVAIGKARVGELEYEVLARQMIA-PPFAAADVDRDDPLWFFYTSGTTG 176 Query: 181 HPKAGMLSHGQMAFVVTNHLADLLPGLTHQSRSLVVAPLSHGAGIHAVVNTARGAA 236 PKAG+L+HGQMAFV+TNH+ADL+PGLTH+SRSLVVAPLSHGAGIHA+VN AR AA Sbjct: 177 RPKAGVLTHGQMAFVLTNHIADLMPGLTHESRSLVVAPLSHGAGIHAMVNVARAAA 232 >B1Y4S3.1 B1Y4S3_LEPCP AMP-dependent synthetase and ligase Length = 532 Score = 262 bits (669), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 135/236 (57%), Positives = 164/236 (69%), Gaps = 10/236 (4%) Query: 2 NLGRLLSDVARRFPDEPGLIFGDGTADGKGDKIATWKQINDRVDTLAHSLQKLGVSKGDK 61 NL +LL AR+FPD PGLI +GD +W QI+ RVD L +L LG+ KGD Sbjct: 8 NLAQLLRQTARQFPDRPGLI--------QGDNRWSWSQIDRRVDALVAALHALGLQKGDC 59 Query: 62 MLVHSRNNLQIFESAWAAFKLGMVWVPTNVRITPPEAAYLGQSSGASVMLYDRGFANYVD 121 +L SRNNL +FE AWAAF++G VWVPTN R+TP E AYLG+SSGA ML + FA + + Sbjct: 60 ILTQSRNNLAMFECAWAAFRMGCVWVPTNFRLTPQEVAYLGESSGARAMLVETCFAGHAE 119 Query: 122 AVKEVSPALKHVIAL-QDPRAGELDFETLATATGAHQSFDEVEVDYEDPLWFFYTSGTTG 180 AV+ +P LKHV+ + D AG LD+E L A A E V ++DPLWFFYTSGTTG Sbjct: 120 AVQAAAPELKHVVWIGADAPAGSLDYEAL-LARHADAPAAEATVAHDDPLWFFYTSGTTG 178 Query: 181 HPKAGMLSHGQMAFVVTNHLADLLPGLTHQSRSLVVAPLSHGAGIHAVVNTARGAA 236 PKA +L+HGQM FVVTNHLADL+PG T S+ VAPLSHGAGIHA++N ARGAA Sbjct: 179 KPKAAILTHGQMGFVVTNHLADLIPGTTETDCSIAVAPLSHGAGIHALLNVARGAA 234 >B2JSJ9.1 B2JSJ9_BURP8 AMP-dependent synthetase and ligase Length = 531 Score = 261 bits (666), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 130/235 (55%), Positives = 160/235 (68%), Gaps = 9/235 (3%) Query: 2 NLGRLLSDVARRFPDEPGLIFGDGTADGKGDKIATWKQINDRVDTLAHSLQKLGVSKGDK 61 NL LL AR+FP ++ D T + W +I+ RVD + +L+ LGV GDK Sbjct: 8 NLAHLLRQSARQFPQRTAVVHRDRTWN--------WSEIDSRVDAMVAALRSLGVRPGDK 59 Query: 62 MLVHSRNNLQIFESAWAAFKLGMVWVPTNVRITPPEAAYLGQSSGASVMLYDRGFANYVD 121 +LV SRN +Q+FES W AF+LG VWVPTN R+TPPE AYLG SSGA M+ + F Y D Sbjct: 60 ILVQSRNCVQMFESCWVAFRLGAVWVPTNFRLTPPEVAYLGSSSGACAMIVEEDFQEYAD 119 Query: 122 AVKEVSPALKHVIALQDPRAGELDFETLATATGAHQSFDEVEVDYEDPLWFFYTSGTTGH 181 AV+ SP L+H++ + PR GE +E L A +S D V VDY+ PLWFFYTSGTTG Sbjct: 120 AVRAASPDLRHIVVIGSPRQGEHSYEDLVAANLGTKSEDAV-VDYDTPLWFFYTSGTTGR 178 Query: 182 PKAGMLSHGQMAFVVTNHLADLLPGLTHQSRSLVVAPLSHGAGIHAVVNTARGAA 236 PKA +L+HGQMAFVV NHLAD+LPGLT S+VVAPLSHGAGI ++N ARGAA Sbjct: 179 PKAAILTHGQMAFVVANHLADVLPGLTELDCSIVVAPLSHGAGIQGLLNVARGAA 233 >C5CZF6.1 C5CZF6_VARPS AMP-dependent synthetase and ligase Length = 529 Score = 255 bits (652), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 133/236 (56%), Positives = 165/236 (69%), Gaps = 9/236 (3%) Query: 1 MNLGRLLSDVARRFPDEPGLIFGDGTADGKGDKIATWKQINDRVDTLAHSLQKLGVSKGD 60 MNL LLS A FP+ PGLI +G++ TW++I+ RVD L +L+ LG+ GD Sbjct: 7 MNLSALLSQTAALFPERPGLI--------QGERQWTWREIDARVDALVQALRALGMRPGD 58 Query: 61 KMLVHSRNNLQIFESAWAAFKLGMVWVPTNVRITPPEAAYLGQSSGASVMLYDRGFANYV 120 K+LV SRNN +FES WAAF+LG VWVP N R+TPPE AYLG +S ASVML + FA +V Sbjct: 59 KLLVMSRNNPALFESCWAAFRLGAVWVPVNFRLTPPEVAYLGSASEASVMLAEDCFAEHV 118 Query: 121 DAVKEVSPALKHVIALQDPRAGELDFETLATATGAHQSFDEVEVDYEDPLWFFYTSGTTG 180 +AVK S L+ V+ + PRA EL +E L A + V+VD + PLW+FYTSGTTG Sbjct: 119 EAVKAASSHLRSVVTIGLPRADELGYEALLAANAGAPA-AMVQVDADQPLWYFYTSGTTG 177 Query: 181 HPKAGMLSHGQMAFVVTNHLADLLPGLTHQSRSLVVAPLSHGAGIHAVVNTARGAA 236 PKA +L+HGQMAFVV NHLADL+PG T S+ VAPLSHGAGIHA++N ARGAA Sbjct: 178 RPKAAVLTHGQMAFVVANHLADLIPGTTEHDCSIAVAPLSHGAGIHALLNVARGAA 233