BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0046.p (276 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPZ1.1 D8IPZ1_HERSS Cation/multidrug efflux pump protein 375 e-102 B2AHF6.1 B2AHF6_CUPTR Multidrug efflux system, subunit C 358 3e-97 Q0KE40.1 Q0KE40_CUPNH Cation/multidrug efflux pump 357 8e-97 D8P5C2.1 D8P5C2_RALSO Multidrug efflux system, subunit C 356 2e-96 D8N1Q0.1 D8N1Q0_RALSO Multidrug efflux system, subunit C 354 6e-96 >D8IPZ1.1 D8IPZ1_HERSS Cation/multidrug efflux pump protein Length = 1078 Score = 375 bits (964), Expect = e-102, Method: Compositional matrix adjust. Identities = 189/254 (74%), Positives = 213/254 (83%), Gaps = 8/254 (3%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLENISRHIE GMKP KAAL+GAREVGFTVLSMSISLIAVFIPILMM GIVGR Sbjct: 399 VVDDAIVVLENISRHIESGMKPYKAALLGAREVGFTVLSMSISLIAVFIPILMMEGIVGR 458 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQE--SEEERKPGRF------FTAVERL 112 LFREFA+TLSVAILVSL+VSLTTTPMMCA LL+ + ++E R+ R + Sbjct: 459 LFREFAITLSVAILVSLVVSLTTTPMMCAQLLRHDPAADEARRQRRHPWLQKIADQSAAI 518 Query: 113 FDSMLRGYERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGD 172 F+ ML Y+R+LAWALR +PLM++ILLATIALNVYLY +PKGFFPQQDTGRLVGGIRGD Sbjct: 519 FEDMLLAYQRTLAWALRAAPLMMLILLATIALNVYLYKAIPKGFFPQQDTGRLVGGIRGD 578 Query: 173 QSISFQAMRIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVI 232 Q+ISFQAMR KLNEFI+IVR DPAV++V AFTGG RRNGG M++ LKPLSERK SADKV+ Sbjct: 579 QAISFQAMRTKLNEFIDIVRADPAVSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKVV 638 Query: 233 ARLRMKLGHVAXCR 246 ARLR+K VA R Sbjct: 639 ARLRIKTAKVAGAR 652 >B2AHF6.1 B2AHF6_CUPTR Multidrug efflux system, subunit C Length = 1099 Score = 358 bits (920), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 180/241 (74%), Positives = 204/241 (84%), Gaps = 2/241 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLENISRHIE+GMKP+ AAL GAREVGFTVLSMS+SLIAVFIP+LMMGGIVGR Sbjct: 463 VVDDAIVVLENISRHIEEGMKPLAAALRGAREVGFTVLSMSLSLIAVFIPLLMMGGIVGR 522 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LF+EFA+TLSVAILVSL+VSLTTTPMMCA +L+ E K GRFF A ER+F + GY Sbjct: 523 LFQEFAITLSVAILVSLVVSLTTTPMMCARMLR--PVEPEKQGRFFRATERMFQWLHDGY 580 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 RSL+ ALR SPL+ ++L+ATIALNVYLYVIVPKGFFPQQDTGRL+G IR DQ+ SFQAM Sbjct: 581 ARSLSTALRLSPLVWLVLIATIALNVYLYVIVPKGFFPQQDTGRLIGFIRADQATSFQAM 640 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKLG 240 R KL+ FI+IV+ DPAV NVT FTGG +RN G MF+ LKPLSERK SAD +IARLR KL Sbjct: 641 RGKLDNFIKIVQSDPAVVNVTGFTGGSQRNTGQMFVTLKPLSERKESADAIIARLRGKLA 700 Query: 241 H 241 Sbjct: 701 K 701 >Q0KE40.1 Q0KE40_CUPNH Cation/multidrug efflux pump Length = 1099 Score = 357 bits (917), Expect = 8e-97, Method: Compositional matrix adjust. Identities = 179/239 (74%), Positives = 203/239 (84%), Gaps = 2/239 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLENISRHIE+GMKP+ AAL GAREVGFTVLSMS+SLIAVFIP+LMMGGIVGR Sbjct: 463 VVDDAIVVLENISRHIEEGMKPLAAALRGAREVGFTVLSMSLSLIAVFIPLLMMGGIVGR 522 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LF+EFA+TLSVAILVSL+VSLTTTPMMCA +L+ E K GRFF A ER+F + GY Sbjct: 523 LFQEFAITLSVAILVSLVVSLTTTPMMCARMLR--PPEPEKQGRFFRATERMFQWLHDGY 580 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 RSL+ ALR SPL+ ++L+ATIALNVYLYVIVPKGFFPQQDTGRL+G IR DQ+ SFQAM Sbjct: 581 ARSLSTALRLSPLVWLVLIATIALNVYLYVIVPKGFFPQQDTGRLIGFIRADQATSFQAM 640 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKL 239 R KL+ FI+IV+ DPAV NVT FTGG +RN G MF+ LKPLSER SAD +IARLR KL Sbjct: 641 RGKLDNFIKIVQSDPAVVNVTGFTGGSQRNTGQMFVTLKPLSERNESADAIIARLRGKL 699 >D8P5C2.1 D8P5C2_RALSO Multidrug efflux system, subunit C Length = 1033 Score = 356 bits (913), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 178/240 (74%), Positives = 200/240 (83%), Gaps = 2/240 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLEN+SRHIE GM+P++AAL GAREVGFTV+SMS SLIAVFIP+LMMGGIVGR Sbjct: 399 VVDDAIVVLENVSRHIENGMRPMQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGR 458 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LFREFAVTLSVAILVSL++SLTTTPMMCA LLK SEEE PG F ER F +L GY Sbjct: 459 LFREFAVTLSVAILVSLVISLTTTPMMCARLLKPASEEE--PGWFHRKTERFFTLLLDGY 516 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 SLAWALR S L ++ILLAT+ LNVYLY++VPKGFFPQQD GRL+G I+ DQSISFQAM Sbjct: 517 RHSLAWALRHSWLTLLILLATVCLNVYLYIVVPKGFFPQQDVGRLMGFIQADQSISFQAM 576 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKLG 240 R KL +FI IV+QDPAV NV FTGG + N G MFI LKPL+ERK+SAD+VI RLR KL Sbjct: 577 RTKLVDFIHIVQQDPAVENVVGFTGGSQINSGQMFIQLKPLAERKLSADQVINRLRGKLA 636 >D8N1Q0.1 D8N1Q0_RALSO Multidrug efflux system, subunit C Length = 1033 Score = 354 bits (909), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 179/240 (74%), Positives = 198/240 (82%), Gaps = 2/240 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLEN+SRHIE GM+P++AAL GAREVGFTV+SMS SLIAVFIP+LMMGGIVGR Sbjct: 399 VVDDAIVVLENVSRHIENGMRPMQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGR 458 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LFREFAVTLSVAILVSL +SLTTTPMMCA LLK SEEE PG F E F +L GY Sbjct: 459 LFREFAVTLSVAILVSLAISLTTTPMMCARLLKPASEEE--PGWFHRKTESFFTLLLDGY 516 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 SLAWALR S L ++ILLAT+ LNVYLYV+VPKGFFPQQD GRL+G I+ DQSISFQAM Sbjct: 517 RHSLAWALRHSWLTLLILLATVCLNVYLYVVVPKGFFPQQDVGRLMGFIQADQSISFQAM 576 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKLG 240 R KL +FI IV+QDPAV NV FTGG + N G MFI LKPLSERK+SAD+VI RLR KL Sbjct: 577 RTKLVDFIHIVQQDPAVENVVGFTGGSQINSGQMFIQLKPLSERKLSADQVINRLRGKLA 636