BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0009.p (221 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY85.1 D8IY85_HERSS GTP cyclohydrolase I protein 416 e-114 Q7NVI2.1 Q7NVI2_CHRVO GTP cyclohydrolase I EC=3.5.4.16 388 e-106 B1XZX0.1 B1XZX0_LEPCP GTP cyclohydrolase I EC=3.5.4.16 376 e-102 Q1LG68.1 Q1LG68_RALME GTP cyclohydrolase I EC=3.5.4.16 366 1e-99 B3RBI7.1 B3RBI7_CUPTR GTP cyclohydrolase I EC=3.5.4.16 363 6e-99 >D8IY85.1 D8IY85_HERSS GTP cyclohydrolase I protein Length = 254 Score = 416 bits (1068), Expect = e-114, Method: Compositional matrix adjust. Identities = 198/220 (90%), Positives = 207/220 (94%) Query: 1 VSNRIRARIKAAGVRFHANDNISAFIEDGELDALQAEVQAKLAGVLESLVIDVDSDHNTQ 60 VS RIR RIKAAGVRFHANDNISAFI++GEL LQAEVQ KLA VLESLVIDV+SDHNTQ Sbjct: 31 VSARIRQRIKAAGVRFHANDNISAFIKEGELAELQAEVQGKLAAVLESLVIDVESDHNTQ 90 Query: 61 DTAKRVAKMYLQEVFRGRYLPAPPVTEFPNIERLNELMIVGPITVRSACSHHLCPIMGKV 120 DTAKRVAKMYL EVF+GRY APPVTEFPNIERLNELMIVGPITVRSACSHHLCPIMGKV Sbjct: 91 DTAKRVAKMYLNEVFKGRYQAAPPVTEFPNIERLNELMIVGPITVRSACSHHLCPIMGKV 150 Query: 121 WVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAIVMEADH 180 WVGVMPNEHSNLIGLSKYARL+EW+MSRPQIQEEAVSQ A LLM+KLQPDGLAIVMEADH Sbjct: 151 WVGVMPNEHSNLIGLSKYARLLEWVMSRPQIQEEAVSQAADLLMQKLQPDGLAIVMEADH 210 Query: 181 FCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALIRK 220 FCMHWRGVKD +SKMINSVMRGSFLRDANLRREFLALI + Sbjct: 211 FCMHWRGVKDMDSKMINSVMRGSFLRDANLRREFLALITQ 250 >Q7NVI2.1 Q7NVI2_CHRVO GTP cyclohydrolase I EC=3.5.4.16 Length = 232 Score = 388 bits (997), Expect = e-106, Method: Compositional matrix adjust. Identities = 178/220 (80%), Positives = 203/220 (92%) Query: 1 VSNRIRARIKAAGVRFHANDNISAFIEDGELDALQAEVQAKLAGVLESLVIDVDSDHNTQ 60 +S RIR R++AAG RFHANDNISAFIEDGELDALQ EVQAKL GVLESLVID +DHNTQ Sbjct: 13 ISQRIRYRLQAAGARFHANDNISAFIEDGELDALQEEVQAKLKGVLESLVIDTANDHNTQ 72 Query: 61 DTAKRVAKMYLQEVFRGRYLPAPPVTEFPNIERLNELMIVGPITVRSACSHHLCPIMGKV 120 +TAKRVAKM+++EVFRGRY+ PP TEFPN+E LNELMI+GPITVRSACSHHLCPI+G+V Sbjct: 73 ETAKRVAKMFVREVFRGRYVSMPPCTEFPNVEHLNELMIIGPITVRSACSHHLCPIIGRV 132 Query: 121 WVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAIVMEADH 180 WVGV+PNE SNLIGLSKYARLI+W+M+RPQIQEEAVSQ+A LLM+KLQPDGLAIVMEADH Sbjct: 133 WVGVLPNEASNLIGLSKYARLIDWVMTRPQIQEEAVSQIADLLMQKLQPDGLAIVMEADH 192 Query: 181 FCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALIRK 220 FCMHWRGVKD+ SKM NSVMRGSFL + +LR+EFL+L+RK Sbjct: 193 FCMHWRGVKDSNSKMTNSVMRGSFLTNPDLRKEFLSLMRK 232 >B1XZX0.1 B1XZX0_LEPCP GTP cyclohydrolase I EC=3.5.4.16 Length = 250 Score = 376 bits (966), Expect = e-102, Method: Compositional matrix adjust. Identities = 175/219 (79%), Positives = 197/219 (89%) Query: 1 VSNRIRARIKAAGVRFHANDNISAFIEDGELDALQAEVQAKLAGVLESLVIDVDSDHNTQ 60 VS RIR RIKAA RFHANDNI+ FI GEL+AL EV K++ VL SLVID +SDHNTQ Sbjct: 28 VSVRIRERIKAARQRFHANDNIAEFIRPGELEALLDEVSGKMSAVLSSLVIDTESDHNTQ 87 Query: 61 DTAKRVAKMYLQEVFRGRYLPAPPVTEFPNIERLNELMIVGPITVRSACSHHLCPIMGKV 120 DTA+RVAKMYL+EVFRGRY+ PPVTEFPN+ERLNELMIVGP+TVRSACSHHLCPI+GK+ Sbjct: 88 DTARRVAKMYLKEVFRGRYVEQPPVTEFPNVERLNELMIVGPVTVRSACSHHLCPIVGKL 147 Query: 121 WVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAIVMEADH 180 W+GVMPNEHSNLIGLSKYARL EWIMSRPQIQEEAV+QVA LL +K+QPDGLA+VMEADH Sbjct: 148 WIGVMPNEHSNLIGLSKYARLAEWIMSRPQIQEEAVTQVADLLQDKMQPDGLAVVMEADH 207 Query: 181 FCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALIR 219 FCM WRGVKD +SKMINSVMRGSFL+D NLRREFL+L++ Sbjct: 208 FCMSWRGVKDMDSKMINSVMRGSFLKDPNLRREFLSLLQ 246 >Q1LG68.1 Q1LG68_RALME GTP cyclohydrolase I EC=3.5.4.16 Length = 241 Score = 366 bits (939), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 171/218 (78%), Positives = 194/218 (88%) Query: 1 VSNRIRARIKAAGVRFHANDNISAFIEDGELDALQAEVQAKLAGVLESLVIDVDSDHNTQ 60 VSNRIRARI+AAG RFHANDNIS IE GEL+ALQAEV+A++ VL +LVIDVD DHNT+ Sbjct: 19 VSNRIRARIEAAGERFHANDNISRHIEHGELEALQAEVEARMEDVLRTLVIDVDQDHNTR 78 Query: 61 DTAKRVAKMYLQEVFRGRYLPAPPVTEFPNIERLNELMIVGPITVRSACSHHLCPIMGKV 120 +TA+RVAKMYL+E+F GRY AP VTEFPN+E+LNELMIVGPI VRSACSHHLCPI+G + Sbjct: 79 ETARRVAKMYLKEIFAGRYAKAPDVTEFPNVEQLNELMIVGPIRVRSACSHHLCPIIGSL 138 Query: 121 WVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAIVMEADH 180 WVGVMPN HSNLIGLSKYARL EWIM RPQIQEEAV+QVA LL EK+ PDGLAIVMEA+H Sbjct: 139 WVGVMPNRHSNLIGLSKYARLAEWIMCRPQIQEEAVAQVADLLQEKMNPDGLAIVMEAEH 198 Query: 181 FCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALI 218 FCMHWRGV+DT++KM NSVMRGSFL+D LRREFL L+ Sbjct: 199 FCMHWRGVRDTDAKMTNSVMRGSFLKDDKLRREFLTLL 236 >B3RBI7.1 B3RBI7_CUPTR GTP cyclohydrolase I EC=3.5.4.16 Length = 248 Score = 363 bits (933), Expect = 6e-99, Method: Compositional matrix adjust. Identities = 167/218 (76%), Positives = 196/218 (89%) Query: 1 VSNRIRARIKAAGVRFHANDNISAFIEDGELDALQAEVQAKLAGVLESLVIDVDSDHNTQ 60 VS RIRAR++AA RFHANDNI+ +IE GE++ LQAEVQA+L VL +LVIDVD+DHNTQ Sbjct: 26 VSARIRARLEAAQERFHANDNIARYIEPGEMEQLQAEVQARLQDVLRALVIDVDNDHNTQ 85 Query: 61 DTAKRVAKMYLQEVFRGRYLPAPPVTEFPNIERLNELMIVGPITVRSACSHHLCPIMGKV 120 +TA+RVAKMYL+E+F GRY APPVTEFPN+ +LNELMIVGP+ VRSACSHHLCPI+GK+ Sbjct: 86 ETARRVAKMYLKEIFAGRYAKAPPVTEFPNVGQLNELMIVGPLRVRSACSHHLCPIIGKL 145 Query: 121 WVGVMPNEHSNLIGLSKYARLIEWIMSRPQIQEEAVSQVAGLLMEKLQPDGLAIVMEADH 180 W+GVMPN+HSNLIGLSKYARL EWIM RPQIQEEAV+QVA LL EK+ PDGLAIVMEA+H Sbjct: 146 WIGVMPNQHSNLIGLSKYARLAEWIMCRPQIQEEAVAQVADLLQEKMSPDGLAIVMEAEH 205 Query: 181 FCMHWRGVKDTESKMINSVMRGSFLRDANLRREFLALI 218 FCMHWRGV+DT++KM NSVMRGSFL+D +LRREFL L+ Sbjct: 206 FCMHWRGVRDTDAKMTNSVMRGSFLKDDSLRREFLTLL 243