BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0005.p (410 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY82.1 D8IY82_HERSS Permease of the major facilitator superfam... 564 e-159 A6T2N8.1 A6T2N8_JANMA Transporter of the MFS superfamily 426 e-117 B2JN75.1 B2JN75_BURP8 Major facilitator superfamily MFS_1 424 e-116 D5WFS3.1 D5WFS3_BURSC Major facilitator superfamily MFS_1 420 e-115 F2LNF4.1 F2LNF4_BURGA Major facilitator superfamily MFS_1 415 e-114 >D8IY82.1 D8IY82_HERSS Permease of the major facilitator superfamily protein Length = 475 Score = 564 bits (1454), Expect = e-159, Method: Compositional matrix adjust. Identities = 286/351 (81%), Positives = 312/351 (88%) Query: 1 MEPSKSKAAAAAPVHPVVIAGEGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARD 60 M + AAP +VIAGEGLP ++R AI+ L IAVGLATLDTAIANTALP MA D Sbjct: 1 MSSQPTAPGTAAPSPHIVIAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALD 60 Query: 61 LNTTPAASVWIVTAYQLAMMVSLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLP 120 L TTPAASVWIVTAYQLAMMV+LLPLAALGEI+GYRRIYI GL LFTAASLLCAVAWSLP Sbjct: 61 LQTTPAASVWIVTAYQLAMMVALLPLAALGEIIGYRRIYIWGLVLFTAASLLCAVAWSLP 120 Query: 121 ALTVARFLQGLGGAGIMSVNTALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILA 180 L +ARFLQGLGGAGIMSVNTALIR+IYPTRSLGRGVG+NTLIVAI+FT+GPSVASGILA Sbjct: 121 TLVMARFLQGLGGAGIMSVNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILA 180 Query: 181 IAPWPWLFAVNVPLGIIGLVMAVPSLPYTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAH 240 IAPWPWLFAVNVPLG++ +V+AVPSLP+T + H FD++SALLNAAAFGLLI+AIGEGAH Sbjct: 181 IAPWPWLFAVNVPLGVLAVVLAVPSLPHTSLARHAFDLRSALLNAAAFGLLILAIGEGAH 240 Query: 241 QAAPSVVVLEFVAALVCGYLLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLA 300 QA SVV LE AA++CG L++RE SHPAPMLPVDLFR PMFSLSA+TAVCSFAAQGLA Sbjct: 241 QAQASVVGLELAAAILCGLFLLKRELSHPAPMLPVDLFRHPMFSLSAVTAVCSFAAQGLA 300 Query: 301 FVSLPFFFHHDLGRSQVEIGLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGG 351 FVSLPFFFHHDLGRSQVEIGLLMTPWPVAVAIMAPIAGRMSD YP GMLGG Sbjct: 301 FVSLPFFFHHDLGRSQVEIGLLMTPWPVAVAIMAPIAGRMSDRYPVGMLGG 351 >A6T2N8.1 A6T2N8_JANMA Transporter of the MFS superfamily Length = 469 Score = 426 bits (1094), Expect = e-117, Method: Compositional matrix adjust. Identities = 220/358 (61%), Positives = 269/358 (75%) Query: 1 MEPSKSKAAAAAPVHPVVIAGEGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARD 60 M S + A V+ V+ +GLP ++R AI+++ I VG+A+LDTAIANTALP MA Sbjct: 1 MGSSDMSRQSGAVVNHEVLEQDGLPENERRWAIVSVAIGVGMASLDTAIANTALPAMAMQ 60 Query: 61 LNTTPAASVWIVTAYQLAMMVSLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLP 120 LN TPA SVWIV YQLAM+ +LLP AALGEI+GYRRI I GL LFTAASL CA AWSLP Sbjct: 61 LNATPADSVWIVNIYQLAMVATLLPFAALGEILGYRRIAIFGLLLFTAASLACAYAWSLP 120 Query: 121 ALTVARFLQGLGGAGIMSVNTALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILA 180 L +ARF QG+G + IM VNTAL+R IYP R LGRG+G N L+VA++F +GP+ AS IL+ Sbjct: 121 TLVIARFFQGVGASAIMGVNTALLRSIYPARMLGRGLGTNALVVAVAFAVGPTTASLILS 180 Query: 181 IAPWPWLFAVNVPLGIIGLVMAVPSLPYTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAH 240 + WPWLFA+NVPLG+ +A LP+T ++TH FD +A+ NA FGLLI+AIGEGAH Sbjct: 181 VWSWPWLFAINVPLGLFAYFLARKVLPHTKRATHKFDALTAIYNAGGFGLLILAIGEGAH 240 Query: 241 QAAPSVVVLEFVAALVCGYLLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLA 300 + V LE ALV LL+RR+ H APMLPVDLFRRP+F+LSA+TAVC+FAAQ LA Sbjct: 241 LSDAKTVALELFGALVFFILLLRRQKGHAAPMLPVDLFRRPLFTLSALTAVCTFAAQSLA 300 Query: 301 FVSLPFFFHHDLGRSQVEIGLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGGFGLALLA 358 FVSLPF+F LGRS +E G L+TPW V V IMAPIAGR+SDHYP GMLGG GL++L+ Sbjct: 301 FVSLPFYFETVLGRSAIETGFLITPWAVMVGIMAPIAGRLSDHYPPGMLGGVGLSVLS 358 >B2JN75.1 B2JN75_BURP8 Major facilitator superfamily MFS_1 Length = 488 Score = 424 bits (1089), Expect = e-116, Method: Compositional matrix adjust. Identities = 220/344 (63%), Positives = 267/344 (77%), Gaps = 3/344 (0%) Query: 15 HPVVIAGEGLPADKRAIAIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTA 74 H +A + A R A+ ++++V LA+LDTAIANTALP MA DL+ PAASVWI+ A Sbjct: 21 HSARVADVPMSAGHR-FAMAAIMLSVALASLDTAIANTALPAMAADLHAKPAASVWIINA 79 Query: 75 YQLAMMVSLLPLAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGA 134 YQLAM+ +LLPLAALG+IVG+RRIYIGG+ +FT ASL CA++ +LP L AR +QGLG A Sbjct: 80 YQLAMVATLLPLAALGDIVGHRRIYIGGIGVFTVASLACALSPTLPVLAGARVVQGLGAA 139 Query: 135 GIMSVNTALIRYIYPTRSLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPL 194 IMSVNTALI+++YP LGRGVG+N L+V +SF +GP+VAS IL++A WPWLFAVNVPL Sbjct: 140 AIMSVNTALIKHLYPPHQLGRGVGLNALVVGVSFAVGPTVASLILSVADWPWLFAVNVPL 199 Query: 195 GIIGLVMAVPSLPYTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVA- 253 G++ L A+P LP TP+ THHFD +ALLN F LI A+GE A Q APS +VL A Sbjct: 200 GVLALSFALPGLPRTPRGTHHFDRVAALLNVITFAALIFALGEAA-QRAPSTIVLGAAAI 258 Query: 254 ALVCGYLLMRREASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLG 313 A+V G LLMRREA HPAPMLPVDLF+ P+F+LSA+TAVCSFAAQGLAFVSLPF+F L Sbjct: 259 AIVFGALLMRREAGHPAPMLPVDLFKLPVFALSAVTAVCSFAAQGLAFVSLPFYFEDVLH 318 Query: 314 RSQVEIGLLMTPWPVAVAIMAPIAGRMSDHYPAGMLGGFGLALL 357 RSQVE G LMTPWPV VA+ AP AGR+SD YP G+LG GLA+L Sbjct: 319 RSQVETGFLMTPWPVIVALAAPFAGRLSDRYPPGLLGAIGLAIL 362 >D5WFS3.1 D5WFS3_BURSC Major facilitator superfamily MFS_1 Length = 485 Score = 420 bits (1080), Expect = e-115, Method: Compositional matrix adjust. Identities = 215/333 (64%), Positives = 265/333 (79%), Gaps = 2/333 (0%) Query: 26 ADKRAIAIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTAYQLAMMVSLLP 85 A++RA+A I ++AV LATLDTAIANTALP +A DL+ PAASVWI+ AYQLAM+ +LLP Sbjct: 33 ANRRAMAAI--MLAVALATLDTAIANTALPAIAGDLHAAPAASVWIINAYQLAMVATLLP 90 Query: 86 LAALGEIVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGAGIMSVNTALIR 145 LAALG+IVG+RRIYIGG+ALFT +SL CA+A +LP LT AR +QGLG + IMSVNTALIR Sbjct: 91 LAALGDIVGHRRIYIGGIALFTLSSLGCALAPTLPLLTAARIVQGLGASAIMSVNTALIR 150 Query: 146 YIYPTRSLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPLGIIGLVMAVPS 205 Y+YP LGRG+G N LIV +SF +GP+VAS IL++A WPWLFAVNVPLG++ L A+P+ Sbjct: 151 YLYPPHRLGRGLGTNALIVGVSFAVGPTVASLILSVATWPWLFAVNVPLGVLALSFAMPA 210 Query: 206 LPYTPKSTHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVAALVCGYLLMRRE 265 LP+T + H FD +ALLN F LI A+GE A + + +V+ A+V G LL+RRE Sbjct: 211 LPHTAQGRHQFDPVAALLNVVTFAALIFALGEAAQRVSMQIVLSATAIAVVFGLLLIRRE 270 Query: 266 ASHPAPMLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEIGLLMTP 325 A HPAPMLPVDLF+RP+F+LSA+TAVCSFAAQGLAFVSLPF+F L RSQVE G LMTP Sbjct: 271 AGHPAPMLPVDLFKRPVFALSAVTAVCSFAAQGLAFVSLPFYFEDVLLRSQVETGFLMTP 330 Query: 326 WPVAVAIMAPIAGRMSDHYPAGMLGGFGLALLA 358 WPV VA+ AP+AG +SD YP G+LG GLA+L+ Sbjct: 331 WPVVVALAAPLAGGLSDRYPPGLLGAIGLAVLS 363 >F2LNF4.1 F2LNF4_BURGA Major facilitator superfamily MFS_1 Length = 468 Score = 415 bits (1067), Expect = e-114, Method: Compositional matrix adjust. Identities = 212/327 (64%), Positives = 260/327 (79%) Query: 32 AIITLLIAVGLATLDTAIANTALPVMARDLNTTPAASVWIVTAYQLAMMVSLLPLAALGE 91 A+I +L+AV LATLDTAIANTALP +A DL+T PAASVWI+ AYQLAM+ +LLPLAALG+ Sbjct: 19 AMIAILLAVALATLDTAIANTALPAIAADLHTAPAASVWIINAYQLAMVATLLPLAALGD 78 Query: 92 IVGYRRIYIGGLALFTAASLLCAVAWSLPALTVARFLQGLGGAGIMSVNTALIRYIYPTR 151 IVG+RRIYIGGL +FTAASL CA+ +LP LT AR +QGLG A IMSVNTALIR++YP + Sbjct: 79 IVGHRRIYIGGLVVFTAASLACALVSTLPMLTAARIVQGLGAAAIMSVNTALIRHLYPAQ 138 Query: 152 SLGRGVGINTLIVAISFTIGPSVASGILAIAPWPWLFAVNVPLGIIGLVMAVPSLPYTPK 211 LGRG+G+N LIV +SF +GP+VAS IL++A WPWLFAVNVPLG++ L +A+P+LP+T + Sbjct: 139 RLGRGLGLNALIVGVSFAVGPTVASVILSLADWPWLFAVNVPLGLLALAVAIPALPHTGR 198 Query: 212 STHHFDIKSALLNAAAFGLLIMAIGEGAHQAAPSVVVLEFVAALVCGYLLMRREASHPAP 271 +H FD +A LN F LI A+GE + + + + LV G+LL+RREA HPAP Sbjct: 199 GSHSFDPVAAGLNVVTFAALIFALGETSQRGPLAFSLAAAGVTLVFGWLLIRREAGHPAP 258 Query: 272 MLPVDLFRRPMFSLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEIGLLMTPWPVAVA 331 MLPVDLF+RP+F+LSA+TAVCSFAAQGLAFVSLPF+F L RS VE G LMTPW VA Sbjct: 259 MLPVDLFKRPVFALSALTAVCSFAAQGLAFVSLPFYFEDVLHRSAVETGFLMTPWSAVVA 318 Query: 332 IMAPIAGRMSDHYPAGMLGGFGLALLA 358 + APIAGRMSD YP G+LG GLA+LA Sbjct: 319 LSAPIAGRMSDRYPPGLLGAVGLAILA 345