BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0003.p (308 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY80.1 D8IY80_HERSS Two component sensor histidine kinase prot... 506 e-141 C5T392.1 C5T392_ACIDE Histidine kinase 330 1e-88 A1VSP3.1 A1VSP3_POLNA Integral membrane sensor signal transducti... 330 2e-88 Q21UQ3.1 Q21UQ3_RHOFD Periplasmic sensor signal transduction his... 330 2e-88 Q12EH1.1 Q12EH1_POLSJ Periplasmic sensor signal transduction his... 328 6e-88 >D8IY80.1 D8IY80_HERSS Two component sensor histidine kinase protein EC=2.7.3.- Length = 492 Score = 506 bits (1304), Expect = e-141, Method: Compositional matrix adjust. Identities = 250/308 (81%), Positives = 276/308 (89%) Query: 1 LSNDLEQQRQMLTFQVIGAIVLAVLLAFWFGLWLSRPLARIELAINRLGENRFDQPIIVK 60 LS LEQQRQMLT QV+GAIVLAVLLAF FGLWLSRP+AR+E AI RLG+NRFDQPI V+ Sbjct: 185 LSAALEQQRQMLTAQVVGAIVLAVLLAFCFGLWLSRPMARLEQAIGRLGDNRFDQPIDVR 244 Query: 61 GPADLRRLGQQLDWLRQRLADLEAEKSRFLRHVSHELKTPLAALCEGAALLDDEVAGKLT 120 GPAD+RRLGQQLDWLRQRLADLEAEKSRFLRHVSHELKTPLAALCEGAALLDD VAG+LT Sbjct: 245 GPADIRRLGQQLDWLRQRLADLEAEKSRFLRHVSHELKTPLAALCEGAALLDDGVAGQLT 304 Query: 121 DSQREISRILRQNTQALQNQIEDLLRYNEVAFDAQHINRLPVDLRALLYKVIDDQRLQWT 180 DSQREI+RILRQNTQ+LQ QIEDLLRYNEV+FDAQ I+ +PVDLRALL+KVIDDQRLQW Sbjct: 305 DSQREIARILRQNTQSLQTQIEDLLRYNEVSFDAQRIHPVPVDLRALLHKVIDDQRLQWL 364 Query: 181 ARDLKVEVEGGARTAVLDPDKFAIVLANLLSNAVRFSPRGGTIRFVLSGHEGRVRIDCID 240 AR+LKVE+EG ART V+DP+K AIVLANLLSNAVRFSP+GG IRF+LS G VR++C+D Sbjct: 365 ARELKVEIEGAARTVVVDPEKMAIVLANLLSNAVRFSPQGGFIRFLLSEAPGLVRVECVD 424 Query: 241 QGPGVAATDTVRIFDPFYQGLNQPQGARHGNGIGLSIVREYVLAHNGEVQLVAGPGGAHF 300 QGPGVA TD RIF+PFYQGLNQP AR GNGIGLS+VREYV AH+G+V LV GGAHF Sbjct: 425 QGPGVAPTDAARIFEPFYQGLNQPTAARRGNGIGLSVVREYVQAHSGKVYLVPREGGAHF 484 Query: 301 RIELPDES 308 RIELPDE Sbjct: 485 RIELPDEK 492 >C5T392.1 C5T392_ACIDE Histidine kinase Length = 485 Score = 330 bits (847), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 171/305 (56%), Positives = 216/305 (70%) Query: 1 LSNDLEQQRQMLTFQVIGAIVLAVLLAFWFGLWLSRPLARIELAINRLGENRFDQPIIVK 60 L + LE R+ +T QV+G I LA+ LA G+WL RPL RIE I RLGEN+ DQP+ + Sbjct: 178 LQDQLESSRRNVTHQVVGVIALALALALALGVWLGRPLKRIEGTIRRLGENQLDQPVAIS 237 Query: 61 GPADLRRLGQQLDWLRQRLADLEAEKSRFLRHVSHELKTPLAALCEGAALLDDEVAGKLT 120 GP D+RR+GQQLDWLR RL +L+A+K+RFLRHVSHELKTPLAAL EG ALL DEV G L Sbjct: 238 GPEDVRRVGQQLDWLRLRLLELDADKARFLRHVSHELKTPLAALREGVALLQDEVTGPLA 297 Query: 121 DSQREISRILRQNTQALQNQIEDLLRYNEVAFDAQHINRLPVDLRALLYKVIDDQRLQWT 180 QRE+++IL NT LQ +IE LLR+N AF+A+ + R DL ALL ++ QRLQW Sbjct: 298 PGQREVAQILHHNTLVLQAEIEALLRFNAAAFEARRLQREETDLLALLEAQVEAQRLQWQ 357 Query: 181 ARDLKVEVEGGARTAVLDPDKFAIVLANLLSNAVRFSPRGGTIRFVLSGHEGRVRIDCID 240 A+ L+V VEG + + +D +K ++NLLSNA+RFSPR GT+R LS G VR+D D Sbjct: 358 AKSLRVVVEGPSVSLPIDAEKITSAVSNLLSNAIRFSPREGTVRLTLSRQPGLVRVDISD 417 Query: 241 QGPGVAATDTVRIFDPFYQGLNQPQGARHGNGIGLSIVREYVLAHNGEVQLVAGPGGAHF 300 QGPGVA D RIF+PFY+G++QP G GIGLSIV EY++AH G+V+LV F Sbjct: 418 QGPGVAVEDRSRIFEPFYRGVHQPDSGVRGTGIGLSIVHEYMVAHGGQVRLVEDDVDTLF 477 Query: 301 RIELP 305 R+ELP Sbjct: 478 RVELP 482 >A1VSP3.1 A1VSP3_POLNA Integral membrane sensor signal transduction histidine kinase Length = 487 Score = 330 bits (846), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 168/305 (55%), Positives = 212/305 (69%) Query: 1 LSNDLEQQRQMLTFQVIGAIVLAVLLAFWFGLWLSRPLARIELAINRLGENRFDQPIIVK 60 L LE RQ L QV AIVL V +A FG+W +RPL R+E AI LGENR DQ I + Sbjct: 178 LQEKLETSRQHLAQQVTWAIVLTVFMALAFGVWFTRPLKRLENAIIGLGENRLDQVIAIH 237 Query: 61 GPADLRRLGQQLDWLRQRLADLEAEKSRFLRHVSHELKTPLAALCEGAALLDDEVAGKLT 120 GPADL +G++L+WLR RL++L+A+KSRFLRH+SHELKTPLA+L EG +LL+D VAG L+ Sbjct: 238 GPADLALVGERLNWLRLRLSELDADKSRFLRHISHELKTPLASLREGVSLLEDGVAGPLS 297 Query: 121 DSQREISRILRQNTQALQNQIEDLLRYNEVAFDAQHINRLPVDLRALLYKVIDDQRLQWT 180 QREI++IL+ NT LQ+QIEDLLR+N AF+A+ ++R +DL L+ +D QRLQW Sbjct: 298 HDQREIAQILKHNTGVLQSQIEDLLRFNTAAFEARQLHRQTIDLLQLIEDQVDAQRLQWR 357 Query: 181 ARDLKVEVEGGARTAVLDPDKFAIVLANLLSNAVRFSPRGGTIRFVLSGHEGRVRIDCID 240 AR+L V + G +DP+K LANLLSNA+R+SP GTI LS G V ID D Sbjct: 358 ARELTVNISGEPLKMEVDPEKIGTALANLLSNAIRYSPLKGTIELALSQQPGLVHIDIRD 417 Query: 241 QGPGVAATDTVRIFDPFYQGLNQPQGARHGNGIGLSIVREYVLAHNGEVQLVAGPGGAHF 300 QG GVA D RIF+PFY+G QP+ G+GIGLSIV EY+ AH G ++L+ G HF Sbjct: 418 QGVGVAPADRERIFEPFYRGERQPKDGVRGSGIGLSIVHEYIAAHGGRIELLPQETGTHF 477 Query: 301 RIELP 305 RIE P Sbjct: 478 RIEFP 482 >Q21UQ3.1 Q21UQ3_RHOFD Periplasmic sensor signal transduction histidine kinase Length = 473 Score = 330 bits (845), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 173/305 (56%), Positives = 212/305 (69%) Query: 1 LSNDLEQQRQMLTFQVIGAIVLAVLLAFWFGLWLSRPLARIELAINRLGENRFDQPIIVK 60 L LE R L QV AIVLAV +A FG+W + PL R+E AI LGENR DQ I ++ Sbjct: 164 LEAKLEDSRSHLAQQVTWAIVLAVAMALAFGIWFTVPLKRLEHAIVGLGENRLDQVIAIR 223 Query: 61 GPADLRRLGQQLDWLRQRLADLEAEKSRFLRHVSHELKTPLAALCEGAALLDDEVAGKLT 120 GPADL +GQ+L+WLR RL +L+A+KSRFLRH+SHELKTPLA+L EG +LL+D VAG+L+ Sbjct: 224 GPADLAMVGQRLNWLRLRLVELDADKSRFLRHISHELKTPLASLREGVSLLEDGVAGELS 283 Query: 121 DSQREISRILRQNTQALQNQIEDLLRYNEVAFDAQHINRLPVDLRALLYKVIDDQRLQWT 180 QREI++ILR N LQ QIEDLLR+N AF+A+ ++R +L L+ +D QRLQW Sbjct: 284 PEQREIAQILRHNAGVLQGQIEDLLRFNTAAFEARQLHRRTTNLLELVEAQVDAQRLQWR 343 Query: 181 ARDLKVEVEGGARTAVLDPDKFAIVLANLLSNAVRFSPRGGTIRFVLSGHEGRVRIDCID 240 AR+L V V G LDP+K VLANLLSNA+R+SP G IR LS G VRID D Sbjct: 344 ARELSVIVVGKPILVELDPEKIGTVLANLLSNAIRYSPLKGDIRLELSKLPGLVRIDIHD 403 Query: 241 QGPGVAATDTVRIFDPFYQGLNQPQGARHGNGIGLSIVREYVLAHNGEVQLVAGPGGAHF 300 QG GVA D RIF+PFY+G QP G+GIGLSIV EY+ AH G ++L+ GGAHF Sbjct: 404 QGVGVALADRERIFEPFYRGERQPSDVVRGSGIGLSIVHEYIAAHGGRIELLPDQGGAHF 463 Query: 301 RIELP 305 RIE P Sbjct: 464 RIEFP 468 >Q12EH1.1 Q12EH1_POLSJ Periplasmic sensor signal transduction histidine kinase Length = 473 Score = 328 bits (841), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 174/308 (56%), Positives = 215/308 (69%) Query: 1 LSNDLEQQRQMLTFQVIGAIVLAVLLAFWFGLWLSRPLARIELAINRLGENRFDQPIIVK 60 L LE RQ L QV AI LAV++A FG+W + PL R+E AI LGENR DQ I ++ Sbjct: 164 LEGRLEASRQRLAQQVGWAIALAVVMALAFGIWFTLPLKRLEHAIVGLGENRLDQVIAIQ 223 Query: 61 GPADLRRLGQQLDWLRQRLADLEAEKSRFLRHVSHELKTPLAALCEGAALLDDEVAGKLT 120 GPADL +GQ+L+WLR RL +L+A+KSRFLRH+SHELKTPLA+L EG +LL+D VAG L+ Sbjct: 224 GPADLALVGQRLNWLRLRLVELDADKSRFLRHISHELKTPLASLREGVSLLEDGVAGPLS 283 Query: 121 DSQREISRILRQNTQALQNQIEDLLRYNEVAFDAQHINRLPVDLRALLYKVIDDQRLQWT 180 D QREI++IL+ NT LQ QIEDLLR+N AF+A+ + R +DL L+ + +D QRLQW Sbjct: 284 DDQREIAQILKHNTGVLQGQIEDLLRFNTAAFEARQLRRQTLDLLQLMEEQVDAQRLQWR 343 Query: 181 ARDLKVEVEGGARTAVLDPDKFAIVLANLLSNAVRFSPRGGTIRFVLSGHEGRVRIDCID 240 AR+L V V G LDP+K LANLLSNA+R+SP G IR L GRVRID D Sbjct: 344 ARELSVAVVGEPLRMELDPEKIGTALANLLSNAIRYSPPRGMIRLELVALPGRVRIDIHD 403 Query: 241 QGPGVAATDTVRIFDPFYQGLNQPQGARHGNGIGLSIVREYVLAHNGEVQLVAGPGGAHF 300 QG GVAA D RIF+PF++G QP G+GIGLSIV EY+ AH G ++L+ GAH Sbjct: 404 QGIGVAAADRERIFEPFFRGERQPADVVRGSGIGLSIVHEYIAAHGGRLELLPDQPGAHL 463 Query: 301 RIELPDES 308 RIELP S Sbjct: 464 RIELPHVS 471