BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0007.p (532 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0G1.1 D8J0G1_HERSS Malate synthase EC=2.3.3.9 1047 0.0 A1X1L9.1 A1X1L9_9BURK Malate synthase EC=2.3.3.9 976 0.0 Q1LNK3.1 Q1LNK3_RALME Malate synthase EC=2.3.3.9 962 0.0 B3R2L1.1 B3R2L1_CUPTR Malate synthase EC=2.3.3.9 955 0.0 Q46ZW8.1 Q46ZW8_CUPPJ Malate synthase EC=2.3.3.9 950 0.0 >D8J0G1.1 D8J0G1_HERSS Malate synthase EC=2.3.3.9 Length = 528 Score = 1047 bits (2707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 504/532 (94%), Positives = 518/532 (97%), Gaps = 4/532 (0%) Query: 1 MTQLTLPAGMQISGEIKPGYEQILTPDALALVAKLSRAFESRRQELLAVRVERVKRLDAG 60 MTQL LP GM+ISG+IKPGYE ILT +AL+LVAKLSRAFE RRQELLA R ERVKRLDAG Sbjct: 1 MTQLKLPTGMEISGDIKPGYENILTFEALSLVAKLSRAFEGRRQELLAARAERVKRLDAG 60 Query: 61 ERPDFLPETANIRSGDWKIAPIPEALKCRRVEITGPVERKMVINAFNSGADSYMTDFEDS 120 ERPDFL ET +IR+GDWKIAPIPEALKCRRVEITGPVERKMVINAFNSGADSYMTDFEDS Sbjct: 61 ERPDFLKETESIRTGDWKIAPIPEALKCRRVEITGPVERKMVINAFNSGADSYMTDFEDS 120 Query: 121 NSPVWDNQISGQINLFDAIRRTISLESNGKSYKLNDKIATLVVRPRGWHLDEKHVTIDGK 180 NSPVWDNQISGQINL+DAIRRTISLESNGKSYKLNDKIATLVVRPRGWHLDEKHVT+DGK Sbjct: 121 NSPVWDNQISGQINLYDAIRRTISLESNGKSYKLNDKIATLVVRPRGWHLDEKHVTLDGK 180 Query: 181 RISGGIFDFALFLFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMAQNEIGLPQGT 240 RISGGIFDFALFLFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMAQNEIGLPQGT Sbjct: 181 RISGGIFDFALFLFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMAQNEIGLPQGT 240 Query: 241 IKATVLIETITAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVT 300 IKATVLIETITAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVT Sbjct: 241 IKATVLIETITAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVT 300 Query: 301 MTAPFMRSYALLLLKTCHKRGAPAIINYIGGMSALIPIKNDPEKNAIAMQGIINDKRRDA 360 MT+PFMR+YALLLLKTCHKRGAPA IGGMSALIPIKNDPEKNAIAMQGIINDKRRDA Sbjct: 301 MTSPFMRAYALLLLKTCHKRGAPA----IGGMSALIPIKNDPEKNAIAMQGIINDKRRDA 356 Query: 361 TDGYDGGWVAHPGLVEPSMKEFVAVLGDKPNQFEKQRPDVDVKAADLLNFQPETPITEAG 420 TDGYDGGWVAHPGLVE SMKEFVAVLGDKPNQFEKQRPDVDVKAADLLNFQPETPITEAG Sbjct: 357 TDGYDGGWVAHPGLVEASMKEFVAVLGDKPNQFEKQRPDVDVKAADLLNFQPETPITEAG 416 Query: 421 LRYNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRAQVWQWIRSSKGNLEDGRKVTA 480 LRYNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRAQVWQWIRS+KGNLEDGRKVTA Sbjct: 417 LRYNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRAQVWQWIRSAKGNLEDGRKVTA 476 Query: 481 DMVRAMIPEELAKVKEVAGNGPTYDRAAKIFEDMSTSETFAEFLTLPLYEEI 532 DMVRAMIPEELAKVK+VAG+GPTYDRAAKIFE+MSTSETFAEFLTLPLYEEI Sbjct: 477 DMVRAMIPEELAKVKQVAGDGPTYDRAAKIFEEMSTSETFAEFLTLPLYEEI 528 >A1X1L9.1 A1X1L9_9BURK Malate synthase EC=2.3.3.9 Length = 532 Score = 976 bits (2523), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/536 (87%), Positives = 501/536 (93%), Gaps = 8/536 (1%) Query: 1 MTQ--LTLPAGMQISGEIKPGYEQILTPDALALVAKLSRAFESRRQELLAVRVERVKRLD 58 MTQ + LP GMQI+GEI PGYEQILTP ALALVAKL+RAFE RRQELLAVRVERVKRLD Sbjct: 1 MTQNTIALPEGMQITGEIAPGYEQILTPAALALVAKLTRAFEPRRQELLAVRVERVKRLD 60 Query: 59 AGERPDFLPETANIRSGDWKIAPIPEALKCRRVEITGPVERKMVINAFNSGADSYMTDFE 118 AGERPDFLPETA+IR GDWKIAPIP+AL+CRRVEITGPVERKMVINAFNSGADSYMTDFE Sbjct: 61 AGERPDFLPETAHIRDGDWKIAPIPKALECRRVEITGPVERKMVINAFNSGADSYMTDFE 120 Query: 119 DSNSPVWDNQISGQINLFDAIRRTISLESNGKSYKLNDKIATLVVRPRGWHLDEKHVTID 178 DSN+P WDNQ++GQIN+FDA+R+TISLE NGKSYKLNDKIATLVVRPRGWHLDEKHV +D Sbjct: 121 DSNTPNWDNQLTGQINMFDAVRKTISLEQNGKSYKLNDKIATLVVRPRGWHLDEKHVLVD 180 Query: 179 GKRISGGIFDFALFLFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMAQNEIGLPQ 238 GKRISGGIFDFALF+FHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVM QNE+GLPQ Sbjct: 181 GKRISGGIFDFALFMFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMTQNELGLPQ 240 Query: 239 GTIKATVLIETITAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAK 298 GTIKATVLIETI AAFEM+EILYEL+EHS+GLNAGRWDYIFSCIKKFK DKDFCLADRAK Sbjct: 241 GTIKATVLIETILAAFEMDEILYELKEHSSGLNAGRWDYIFSCIKKFKLDKDFCLADRAK 300 Query: 299 VTMTAPFMRSYALLLLKTCHKRGAPAIINYIGGMSALIPIKNDPEKNAIAMQGIINDKRR 358 VTMTAPFMR+YALLLLKTCHKRGAPA IGGM+ALIPIKNDPEKN IAM G+ NDK R Sbjct: 301 VTMTAPFMRAYALLLLKTCHKRGAPA----IGGMAALIPIKNDPEKNDIAMGGVRNDKAR 356 Query: 359 DATDGYDGGWVAHPGLVEPSMKEFVAVLGDKPNQFEKQRPDVDVKAADLLNFQPETPITE 418 DATDGYDGGWVAHPGLVE +M EF VLGDKPNQ EKQRPD+DVKA+DLLNFQPE PITE Sbjct: 357 DATDGYDGGWVAHPGLVELAMGEFTKVLGDKPNQIEKQRPDIDVKASDLLNFQPEAPITE 416 Query: 419 AGLRYNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRAQVWQWIRSSKGNLEDGRKV 478 AGLRYNINVGIHYLG+WLAGNGCVPIHNLMEDAATAEISR+QVWQWIRSSKG LEDGRKV Sbjct: 417 AGLRYNINVGIHYLGSWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSSKGVLEDGRKV 476 Query: 479 TADMVRAMIPEELAKVKEVA--GNGPTYDRAAKIFEDMSTSETFAEFLTLPLYEEI 532 TA+MVRAMIPEELAKV+ A GNGPTY RA +IFE+MSTSE+FAEFLTLPLYEEI Sbjct: 477 TAEMVRAMIPEELAKVQRDAPGGNGPTYVRAGQIFEEMSTSESFAEFLTLPLYEEI 532 >Q1LNK3.1 Q1LNK3_RALME Malate synthase EC=2.3.3.9 Length = 527 Score = 962 bits (2487), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/529 (86%), Positives = 491/529 (92%), Gaps = 4/529 (0%) Query: 4 LTLPAGMQISGEIKPGYEQILTPDALALVAKLSRAFESRRQELLAVRVERVKRLDAGERP 63 +TLPAGM+I+GEI P YE ILTP+ALALV KL RAFE+RRQELLA RV R KRLDAGE P Sbjct: 3 ITLPAGMKITGEILPAYEDILTPEALALVDKLHRAFEARRQELLAARVARTKRLDAGELP 62 Query: 64 DFLPETANIRSGDWKIAPIPEALKCRRVEITGPVERKMVINAFNSGADSYMTDFEDSNSP 123 DFLPET +IR GDWK+AP+P+AL+CRRVEITGPVE KMVINAFNSGADSYMTDFEDSN+P Sbjct: 63 DFLPETKSIREGDWKVAPVPKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNTP 122 Query: 124 VWDNQISGQINLFDAIRRTISLESNGKSYKLNDKIATLVVRPRGWHLDEKHVTIDGKRIS 183 W NQ+ GQ+NL A+RRT++L+SNGK YKLNDKIATL VRPRGWHLDEKHVTIDGKR+S Sbjct: 123 NWHNQMQGQVNLKSAVRRTLTLDSNGKHYKLNDKIATLQVRPRGWHLDEKHVTIDGKRVS 182 Query: 184 GGIFDFALFLFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMAQNEIGLPQGTIKA 243 GGIFDFALFLFHNAKEQ+ARGAGP+FYLPKMESHLEARLWNDIFVMAQ E+GLPQGT+KA Sbjct: 183 GGIFDFALFLFHNAKEQIARGAGPFFYLPKMESHLEARLWNDIFVMAQKEVGLPQGTVKA 242 Query: 244 TVLIETITAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVTMTA 303 TVLIETI AAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFK DK+FCLADRAKVTMT+ Sbjct: 243 TVLIETILAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKVDKNFCLADRAKVTMTS 302 Query: 304 PFMRSYALLLLKTCHKRGAPAIINYIGGMSALIPIKNDPEKNAIAMQGIINDKRRDATDG 363 PFMR+YALLLLKTCHKRGAPA IGGMSALIPIKNDPEKNAIAMQGII DKRRDATDG Sbjct: 303 PFMRAYALLLLKTCHKRGAPA----IGGMSALIPIKNDPEKNAIAMQGIIGDKRRDATDG 358 Query: 364 YDGGWVAHPGLVEPSMKEFVAVLGDKPNQFEKQRPDVDVKAADLLNFQPETPITEAGLRY 423 YDGGWVAHPGLVEP+MKEFV VLGD+PNQF+KQRPDV+VK ADLLNFQPE PITEAGLR Sbjct: 359 YDGGWVAHPGLVEPAMKEFVDVLGDRPNQFDKQRPDVEVKGADLLNFQPEAPITEAGLRM 418 Query: 424 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRAQVWQWIRSSKGNLEDGRKVTADMV 483 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISR+QVWQWIRS KG LEDGRKVTA+MV Sbjct: 419 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGRKVTAEMV 478 Query: 484 RAMIPEELAKVKEVAGNGPTYDRAAKIFEDMSTSETFAEFLTLPLYEEI 532 RA+IPEELAKV+EV G G TYDRAA+IFE MSTSE FAEFLTLPLYEE+ Sbjct: 479 RALIPEELAKVREVVGAGATYDRAAQIFEQMSTSEDFAEFLTLPLYEEV 527 >B3R2L1.1 B3R2L1_CUPTR Malate synthase EC=2.3.3.9 Length = 528 Score = 955 bits (2469), Expect = 0.0, Method: Compositional matrix adjust. Identities = 458/530 (86%), Positives = 489/530 (92%), Gaps = 5/530 (0%) Query: 4 LTLPAGMQISGEIKPGYEQILTPDALALVAKLSRAFESRRQELLAVRVERVKRLDAGERP 63 +TLPAGM+I+GEI P YE ILTP+ALALV KL RAFE RRQELLA RVER KRLDAGE P Sbjct: 3 ITLPAGMKITGEILPAYEDILTPEALALVDKLHRAFEPRRQELLAARVERAKRLDAGEVP 62 Query: 64 DFLPETANIRSGDWKIAPIPEALKCRRVEITGPVERKMVINAFNSGADSYMTDFEDSNSP 123 DFLPET +IR GDWK+AP+P+AL+CRRVEITGPVE KMVINAFNSGADSYMTDFEDSN+P Sbjct: 63 DFLPETKSIREGDWKVAPVPKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNTP 122 Query: 124 VWDNQISGQINLFDAIRRTISLESNGKSYKLNDKIATLVVRPRGWHLDEKHVTIDGKRIS 183 W NQ+ GQ+NL A+RRT++LES GK YKLNDKIATL VRPRGWHLDEKHVTIDGKR+S Sbjct: 123 NWHNQLQGQVNLKAAVRRTLTLESKGKQYKLNDKIATLQVRPRGWHLDEKHVTIDGKRVS 182 Query: 184 GGIFDFALFLFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMAQNEIGLPQGTIKA 243 GGIFDFALFLFHNAKEQ+ARGAGP+FYLPKMESHLEARLWNDIFVMAQ EIGLPQGTIKA Sbjct: 183 GGIFDFALFLFHNAKEQIARGAGPFFYLPKMESHLEARLWNDIFVMAQKEIGLPQGTIKA 242 Query: 244 TVLIETITAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVTMTA 303 TVLIETI AAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVTMTA Sbjct: 243 TVLIETILAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVTMTA 302 Query: 304 PFMRSYALLLLKTCHKRGAPAIINYIGGMSALIPIKNDPEKNAIAMQGIINDKRRDATDG 363 PFMR+YALLLLKTCH RGAPA IGGMSALIPIKNDPEKNAIAM+GII+DKRRDATDG Sbjct: 303 PFMRAYALLLLKTCHSRGAPA----IGGMSALIPIKNDPEKNAIAMEGIISDKRRDATDG 358 Query: 364 YDGGWVAHPGLVEPSMKEFVAVLGDKPNQFEKQRPDVDVKAADLLNFQPETPITEAGLRY 423 YDGGWVAHPGLVEP+MKEFVAVLGDKPNQFEKQRPDV VK ADLL+F+PETPITE GLR Sbjct: 359 YDGGWVAHPGLVEPAMKEFVAVLGDKPNQFEKQRPDVQVKGADLLDFKPETPITEHGLRM 418 Query: 424 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRAQVWQWIRSSKGNLEDGRKVTADMV 483 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISR+QVWQWIRS KG LEDG KVTA++V Sbjct: 419 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGTKVTAELV 478 Query: 484 RAMIPEELAKVKE-VAGNGPTYDRAAKIFEDMSTSETFAEFLTLPLYEEI 532 R +IPEELAKVKE V G+ TYDRAA+IFE MSTSE FAEFLTLPLYEE+ Sbjct: 479 RKLIPEELAKVKELVGGDTRTYDRAAEIFEQMSTSEDFAEFLTLPLYEEV 528 >Q46ZW8.1 Q46ZW8_CUPPJ Malate synthase EC=2.3.3.9 Length = 528 Score = 950 bits (2456), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/530 (86%), Positives = 487/530 (91%), Gaps = 5/530 (0%) Query: 4 LTLPAGMQISGEIKPGYEQILTPDALALVAKLSRAFESRRQELLAVRVERVKRLDAGERP 63 +TLPAGM I+GEI P YE ILTP+ALALV KL RAFE RRQELLA RVER KRLDAGE P Sbjct: 3 ITLPAGMTITGEILPAYEDILTPEALALVDKLHRAFEPRRQELLAARVERAKRLDAGEVP 62 Query: 64 DFLPETANIRSGDWKIAPIPEALKCRRVEITGPVERKMVINAFNSGADSYMTDFEDSNSP 123 DFLPET +IR GDWK+APIP+AL+CRRVEITGPVE KMVINAFNSGADSYMTDFEDSN+P Sbjct: 63 DFLPETKHIREGDWKVAPIPKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNTP 122 Query: 124 VWDNQISGQINLFDAIRRTISLESNGKSYKLNDKIATLVVRPRGWHLDEKHVTIDGKRIS 183 W NQ+ GQ+NL A+RRT++LES GK YKLNDKIATL VRPRGWHLDEKHVTIDGKR+S Sbjct: 123 NWHNQMQGQVNLKAAVRRTLTLESKGKQYKLNDKIATLQVRPRGWHLDEKHVTIDGKRVS 182 Query: 184 GGIFDFALFLFHNAKEQLARGAGPYFYLPKMESHLEARLWNDIFVMAQNEIGLPQGTIKA 243 GGIFDFALFL HNAKEQ+ARG GP+FYLPKMESHLEARLWNDIFVMAQNEIGLPQGTIKA Sbjct: 183 GGIFDFALFLVHNAKEQIARGDGPFFYLPKMESHLEARLWNDIFVMAQNEIGLPQGTIKA 242 Query: 244 TVLIETITAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKNDKDFCLADRAKVTMTA 303 TVLIETI AAFEM+EILYELREHSAGLNAGRWDYIFSCIKKFKNDK+FCLADRAKVTMTA Sbjct: 243 TVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKNDKNFCLADRAKVTMTA 302 Query: 304 PFMRSYALLLLKTCHKRGAPAIINYIGGMSALIPIKNDPEKNAIAMQGIINDKRRDATDG 363 PFMR+YALLLLKTCH RGAPA +GGMSALIPIKNDPEKNAIAMQGIINDK+RDATDG Sbjct: 303 PFMRAYALLLLKTCHYRGAPA----MGGMSALIPIKNDPEKNAIAMQGIINDKKRDATDG 358 Query: 364 YDGGWVAHPGLVEPSMKEFVAVLGDKPNQFEKQRPDVDVKAADLLNFQPETPITEAGLRY 423 YDGGWVAHPGLVEP+MKEFVAVLGDKPNQFEKQRPDV+VK +DLL+FQPETPITE GLR Sbjct: 359 YDGGWVAHPGLVEPAMKEFVAVLGDKPNQFEKQRPDVNVKGSDLLDFQPETPITEGGLRM 418 Query: 424 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRAQVWQWIRSSKGNLEDGRKVTADMV 483 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISR+QVWQWIRS KG LEDG KVTA++V Sbjct: 419 NINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGTKVTAELV 478 Query: 484 RAMIPEELAKVK-EVAGNGPTYDRAAKIFEDMSTSETFAEFLTLPLYEEI 532 R +IPEELAKVK EV G TYDRAA+IFE MSTSE FAEFLTLPLYEE+ Sbjct: 479 RKLIPEELAKVKAEVGGETKTYDRAAEIFEQMSTSEDFAEFLTLPLYEEV 528