BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0033.p (248 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPW8.1 D8IPW8_HERSS Sugar phosphate isomerase/epimerase protei... 316 2e-84 B9Z7V2.1 B9Z7V2_9NEIS PfkB domain protein 200 2e-49 D1RXL3.1 D1RXL3_SEROD Xylose isomerase domain-containing protein 192 5e-47 E5YMH6.1 E5YMH6_9ENTR Xylose isomerase TIM protein 191 5e-47 A8G7T0.1 A8G7T0_SERP5 Xylose isomerase domain protein TIM barrel 191 9e-47 >D8IPW8.1 D8IPW8_HERSS Sugar phosphate isomerase/epimerase protein EC=5.3.1.- Length = 247 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 151/245 (61%), Positives = 188/245 (76%) Query: 3 TPVLVAASAYGADFVRQVGHAHLIPIVAAAGAAGLEIRRELFVELPDFDELHGLLMKHKL 62 +PVLVAASAYGAD VR+VGHA L+P+VAAAGAAGLEIRRELF D L LL +HKL Sbjct: 2 SPVLVAASAYGADLVRRVGHADLVPMVAAAGAAGLEIRRELFDGPQDLPALRELLAQHKL 61 Query: 63 FSVYSAPIELFRKDGSLARDELDQVMGEAQQLQSRFLKVSLGHFSPASNMLDWSRFVAQA 122 FSVYSAP ELF +G R+++ M EA++L +RFLKVSLGHFS AS++ RF++ + Sbjct: 62 FSVYSAPFELFGAEGRFDREQIALAMSEAEELGARFLKVSLGHFSAASDLQSLLRFLSHS 121 Query: 123 PVPLLLENDQTEHGGKLESIANFLAVCSGTGVPVGMTFDMGNWRWSGVDAEVAARTLAAH 182 P+ +LLENDQT GG+LE I +FLA+C+G G GMTFDMGNW W GVD E AAR+LA H Sbjct: 122 PIEVLLENDQTPQGGRLEPIVSFLALCTGNGYAFGMTFDMGNWHWQGVDPETAARSLAPH 181 Query: 183 VQYVHCKGVWNDKGKLKAIPLDEDDAVWRRLFSHFPRGVQRAIEFPIIGKDLEAATRNYV 242 V+YVHCKGV + KGKL+A+PL D+ W+ + +HFP G+ RAIEFP++G DLE TR +V Sbjct: 182 VRYVHCKGVQDHKGKLRAVPLQAQDSHWQEMLAHFPTGILRAIEFPLVGSDLEETTRRHV 241 Query: 243 AMLAS 247 AMLA+ Sbjct: 242 AMLAA 246 >B9Z7V2.1 B9Z7V2_9NEIS PfkB domain protein Length = 567 Score = 200 bits (508), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 121/243 (49%), Positives = 149/243 (61%), Gaps = 1/243 (0%) Query: 5 VLVAASAYGADFVRQVGHAHLIPIVAAAGAAGLEIRRELF-VELPDFDELHGLLMKHKLF 63 V V SAYGA V+ G H I + AAAGAAG+EIRRELF P L L L Sbjct: 4 VNVVTSAYGASLVQTHGQQHFIALAAAAGAAGIEIRRELFPTSPPLLGPLADALAASHLD 63 Query: 64 SVYSAPIELFRKDGSLARDELDQVMGEAQQLQSRFLKVSLGHFSPASNMLDWSRFVAQAP 123 VYSAP+ELF DG L L+ + EA +L + LK+ LGH+ S++ ++ +A +P Sbjct: 64 VVYSAPLELFGTDGQLDLARLELALAEAVELGAGTLKLPLGHYGAVSDLAPLAQRLAGSP 123 Query: 124 VPLLLENDQTEHGGKLESIANFLAVCSGTGVPVGMTFDMGNWRWSGVDAEVAARTLAAHV 183 + LL+ENDQT HGG L + F C GVPVGMTFD+GNW W+ D AA LA +V Sbjct: 124 IRLLVENDQTPHGGTLAPLVAFFTACRAEGVPVGMTFDIGNWHWTDTDPLAAAVALAPYV 183 Query: 184 QYVHCKGVWNDKGKLKAIPLDEDDAVWRRLFSHFPRGVQRAIEFPIIGKDLEAATRNYVA 243 Y+H KGV GKL A+PL E DA WRRLF+HF + RAIEFP+ G DL A T YVA Sbjct: 184 DYLHGKGVEARGGKLHAVPLSESDAGWRRLFAHFRTDIPRAIEFPLSGGDLAALTARYVA 243 Query: 244 MLA 246 +LA Sbjct: 244 LLA 246 >D1RXL3.1 D1RXL3_SEROD Xylose isomerase domain-containing protein Length = 250 Score = 192 bits (487), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 109/248 (43%), Positives = 140/248 (56%), Gaps = 4/248 (1%) Query: 1 MKTPVLVAASAYGADFVRQVG-HAHLIPIVAAAGAAGLEIRRELFV--ELPDFDELHGLL 57 MK ++V AYG D V+Q G A L+PI+A AGA G+EIRRELF EL L + Sbjct: 1 MKREIIVVTGAYGTDVVQQHGGQAALLPIIAGAGADGVEIRRELFSAQELESLPALAQAI 60 Query: 58 MKHKLFSVYSAPIELFRKDGSLARDELDQVMGEAQQLQSRFLKVSLGHFSPASNMLDWSR 117 + +LF+VYSAP LF +L L ++ EAQ L +R LK+SLGH+ P + + Sbjct: 61 EQQQLFAVYSAPEALFTPQHTL-NPNLPALLAEAQVLHARQLKLSLGHYQPGFDFTELKV 119 Query: 118 FVAQAPVPLLLENDQTEHGGKLESIANFLAVCSGTGVPVGMTFDMGNWRWSGVDAEVAAR 177 + Q PV L++ENDQT G L + F +PV MTFDM NW W G DA AA Sbjct: 120 ALEQHPVKLVVENDQTPDCGILSLLNAFFHAAEDNHLPVSMTFDMANWHWVGQDAFAAAE 179 Query: 178 TLAAHVQYVHCKGVWNDKGKLKAIPLDEDDAVWRRLFSHFPRGVQRAIEFPIIGKDLEAA 237 LA HV YVH K + +A+ LD+ D WR L + P R IEFP+ G LEA Sbjct: 180 RLAQHVSYVHVKAATHGPRGWRAVALDDTDGSWRDLLTRLPLDAPRGIEFPLQGDSLEAV 239 Query: 238 TRNYVAML 245 TR+YV +L Sbjct: 240 TRHYVNLL 247 >E5YMH6.1 E5YMH6_9ENTR Xylose isomerase TIM protein Length = 250 Score = 191 bits (486), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 106/248 (42%), Positives = 142/248 (57%), Gaps = 4/248 (1%) Query: 1 MKTPVLVAASAYGADFVRQVG-HAHLIPIVAAAGAAGLEIRRELF--VELPDFDELHGLL 57 MK ++V +AYG D V ++G A+L+PI+A +GA G+EIRREL EL +L + Sbjct: 1 MKREIVVVTAAYGWDKVNELGGQANLLPIIAESGANGVEIRRELLSQAELQTLGDLTKQI 60 Query: 58 MKHKLFSVYSAPIELFRKDGSLARDELDQVMGEAQQLQSRFLKVSLGHFSPASNMLDWSR 117 +H+LF+VYS P LF DG L L+Q + EA +L +R +K SLGH+ P + + Sbjct: 61 ARHQLFAVYSVPEGLFTPDG-LLNPALEQRLHEAIELNARLVKFSLGHYQPGYDFTALNA 119 Query: 118 FVAQAPVPLLLENDQTEHGGKLESIANFLAVCSGTGVPVGMTFDMGNWRWSGVDAEVAAR 177 + + VPL++ENDQT G L + F A P+ MTFDM NW W DAE+AA+ Sbjct: 120 LLKKYDVPLVVENDQTADCGTLSPLNAFFAAVQDCHSPIRMTFDMANWDWVNEDAEIAAQ 179 Query: 178 TLAAHVQYVHCKGVWNDKGKLKAIPLDEDDAVWRRLFSHFPRGVQRAIEFPIIGKDLEAA 237 LA V YVH K A+ LD D W+ L S P V R IEFP+ G DL A Sbjct: 180 KLAHMVHYVHVKAAEKRVQGWCAVELDNSDGRWKPLLSQLPNQVMRGIEFPLEGDDLTAI 239 Query: 238 TRNYVAML 245 TR+YV +L Sbjct: 240 TRHYVNLL 247 >A8G7T0.1 A8G7T0_SERP5 Xylose isomerase domain protein TIM barrel Length = 250 Score = 191 bits (485), Expect = 9e-47, Method: Compositional matrix adjust. Identities = 107/248 (43%), Positives = 140/248 (56%), Gaps = 4/248 (1%) Query: 1 MKTPVLVAASAYGADFVRQVG-HAHLIPIVAAAGAAGLEIRRELFV--ELPDFDELHGLL 57 M +++ AYG D V+Q+G A L+PI+A AGA G+EIRRELF EL L + Sbjct: 1 MTREIIIVTGAYGTDTVQQLGGQAALLPIIAGAGADGVEIRRELFSAQELQALPALAQAI 60 Query: 58 MKHKLFSVYSAPIELFRKDGSLARDELDQVMGEAQQLQSRFLKVSLGHFSPASNMLDWSR 117 + +LF+VYSAP LF +L L ++ EAQ L +R LK+SLGH+ P + + Sbjct: 61 EQQQLFAVYSAPEALFTPQHTL-NPNLPALLAEAQTLNARQLKLSLGHYQPGFDFTELKV 119 Query: 118 FVAQAPVPLLLENDQTEHGGKLESIANFLAVCSGTGVPVGMTFDMGNWRWSGVDAEVAAR 177 + Q PV L++ENDQT G L + F +PV MTFDM NW W G DA AA Sbjct: 120 ALEQHPVNLVVENDQTPDCGILSLLNAFFHAAEDNRLPVSMTFDMANWHWVGQDAFAAAE 179 Query: 178 TLAAHVQYVHCKGVWNDKGKLKAIPLDEDDAVWRRLFSHFPRGVQRAIEFPIIGKDLEAA 237 LA HV YVH K + +A+ LD+ D WR L + P+ V R IEFP+ G LE Sbjct: 180 RLARHVSYVHVKAATHSLKGWRAVALDDSDGKWRELLTRLPQDVPRGIEFPLQGDSLEDV 239 Query: 238 TRNYVAML 245 TR YV +L Sbjct: 240 TRYYVNLL 247