BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0020.p (315 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4GAJ7.1 A4GAJ7_HERAR NAD-dependent formate dehydrogenase beta s... 410 e-112 D8IPH1.1 D8IPH1_HERSS NAD-dependent formate dehydrogenase beta s... 407 e-111 A6T496.1 A6T496_JANMA NAD-dependent formate dehydrogenase beta s... 407 e-111 B9Z4A2.1 B9Z4A2_9NEIS NADH dehydrogenase (Quinone) EC=1.6.99.5 398 e-109 Q608U7.1 Q608U7_METCA Formate dehydrogenase, beta subunit EC=1.2... 394 e-107 >A4GAJ7.1 A4GAJ7_HERAR NAD-dependent formate dehydrogenase beta subunit EC=1.2.1.2 Length = 525 Score = 410 bits (1054), Expect = e-112, Method: Compositional matrix adjust. Identities = 198/268 (73%), Positives = 223/268 (83%) Query: 2 SIKIYVPRDSAAIALGANDVAAAIRGEAEKRGVEVNIVRNGSRGMFWLEPLVEVETGQGR 61 S+ I+VPRDS A+ALGAN+ AAAI EA+ RG+++ +VRNGSRGMFWLEPLVEV T GR Sbjct: 6 SVTIFVPRDSTALALGANETAAAIVREAKARGIDIKLVRNGSRGMFWLEPLVEVATDAGR 65 Query: 62 VAYGPVDPTDVAGLFDAGFLEDATDAFEHPLAQGLTEEIPYLKKQERLTFARVGITDPVS 121 +A+GP++ +VAGLFDAGF + HP A GLTEEIPYLKKQERL F RVGITDPVS Sbjct: 66 IAFGPIEEHEVAGLFDAGFTTGKAEKQTHPKALGLTEEIPYLKKQERLQFVRVGITDPVS 125 Query: 122 LDDYLAHEGYAGLKRAVGMSSEAIVQEVLDSGLRGRGGAAFPTGIKWKTVAAAKAAQKYI 181 LDDYLAHEGY GLK+A+ M AIVQEV DSGLRGRGGAAFPTGIKWKTV A+A QKYI Sbjct: 126 LDDYLAHEGYVGLKKAIAMEPAAIVQEVTDSGLRGRGGAAFPTGIKWKTVLGAEADQKYI 185 Query: 182 VCNADEGDSGTFSDRMVMEDDPFTLIEGMTIAGLAVGATQGYIYVRSEYPHAIAALNEAI 241 CNADEGDSGTFSDRMVMEDDPF LIEGMTIAGLAV AT+GYIYVRSEYPH+IA LNEAI Sbjct: 186 ACNADEGDSGTFSDRMVMEDDPFMLIEGMTIAGLAVNATEGYIYVRSEYPHSIANLNEAI 245 Query: 242 ASASQNGYLGDNVLGSGKAFCLEVRMGA 269 +A+ GYLG N+LGSG+ F L+VR A Sbjct: 246 VAANAAGYLGKNILGSGRTFNLQVRKAA 273 >D8IPH1.1 D8IPH1_HERSS NAD-dependent formate dehydrogenase beta subunit protein EC=1.2.1.2 Length = 520 Score = 407 bits (1046), Expect = e-111, Method: Compositional matrix adjust. Identities = 198/268 (73%), Positives = 226/268 (84%), Gaps = 4/268 (1%) Query: 2 SIKIYVPRDSAAIALGANDVAAAIRGEAEKRGVEVNIVRNGSRGMFWLEPLVEVETGQGR 61 ++ +YVPRDS A+ALGAN+VAAAI EA KRG + +VRNGSRGMFWLEPLVEV T GR Sbjct: 6 TVTVYVPRDSTALALGANEVAAAITAEAHKRGQSIKLVRNGSRGMFWLEPLVEVATAAGR 65 Query: 62 VAYGPVDPTDVAGLFDAGFLEDATDAFEHPLAQGLTEEIPYLKKQERLTFARVGITDPVS 121 VAYGPV P DVAGLFDAG L+ +H L GLTEEI +LK QERLTFARVGI DP+S Sbjct: 66 VAYGPVAPEDVAGLFDAGLLQGG----QHALHLGLTEEIAFLKNQERLTFARVGIIDPLS 121 Query: 122 LDDYLAHEGYAGLKRAVGMSSEAIVQEVLDSGLRGRGGAAFPTGIKWKTVAAAKAAQKYI 181 L+DYLAHEGY GLK A+ + EAIVQE++ SGLRGRGGAAFPTGIKW+TV A++AQKY+ Sbjct: 122 LEDYLAHEGYVGLKNALAKTPEAIVQEMIASGLRGRGGAAFPTGIKWQTVLRAQSAQKYV 181 Query: 182 VCNADEGDSGTFSDRMVMEDDPFTLIEGMTIAGLAVGATQGYIYVRSEYPHAIAALNEAI 241 VCNADEGDSGTFSDRM+MEDDPFTLIEGMTIAG+AVGAT+GYIYVRSEYPH+IA L +AI Sbjct: 182 VCNADEGDSGTFSDRMIMEDDPFTLIEGMTIAGVAVGATEGYIYVRSEYPHSIATLEQAI 241 Query: 242 ASASQNGYLGDNVLGSGKAFCLEVRMGA 269 A A GYLGD++LGSGK+F LEVR GA Sbjct: 242 AIAHAQGYLGDDILGSGKSFRLEVRKGA 269 >A6T496.1 A6T496_JANMA NAD-dependent formate dehydrogenase beta subunit Length = 518 Score = 407 bits (1045), Expect = e-111, Method: Compositional matrix adjust. Identities = 197/269 (73%), Positives = 225/269 (83%), Gaps = 4/269 (1%) Query: 1 MSIKIYVPRDSAAIALGANDVAAAIRGEAEKRGVEVNIVRNGSRGMFWLEPLVEVETGQG 60 M++ I+VPRDS A+ALGAN+ AAAI EA+ RG+++ +VRNGSRGMFWLEPLVEV T G Sbjct: 1 MTVTIFVPRDSTALALGANETAAAIEREAKARGIDIKLVRNGSRGMFWLEPLVEVATDAG 60 Query: 61 RVAYGPVDPTDVAGLFDAGFLEDATDAFEHPLAQGLTEEIPYLKKQERLTFARVGITDPV 120 R+ +GP++ +VAGLFDAGF T HP A GLTEEIPYLKKQERL F RVGITDPV Sbjct: 61 RIGFGPIEEHEVAGLFDAGF----TTGGSHPKALGLTEEIPYLKKQERLQFVRVGITDPV 116 Query: 121 SLDDYLAHEGYAGLKRAVGMSSEAIVQEVLDSGLRGRGGAAFPTGIKWKTVAAAKAAQKY 180 SL+DYLAH+GY GLK+A+ M AIVQEV DSGLRGRGGAAFPTGIKWKTV A+AAQKY Sbjct: 117 SLEDYLAHDGYVGLKKAIAMEPAAIVQEVTDSGLRGRGGAAFPTGIKWKTVLGAEAAQKY 176 Query: 181 IVCNADEGDSGTFSDRMVMEDDPFTLIEGMTIAGLAVGATQGYIYVRSEYPHAIAALNEA 240 I CNADEGDSGTFSDRMVMEDDPF LIEGMTIAGLAV AT+GYIYVRSEYPH+IA LNEA Sbjct: 177 IACNADEGDSGTFSDRMVMEDDPFMLIEGMTIAGLAVKATEGYIYVRSEYPHSIANLNEA 236 Query: 241 IASASQNGYLGDNVLGSGKAFCLEVRMGA 269 I +A+ GYLG+N+LGSG+ F L+VR A Sbjct: 237 IVAANAAGYLGENILGSGRTFNLQVRKAA 265 >B9Z4A2.1 B9Z4A2_9NEIS NADH dehydrogenase (Quinone) EC=1.6.99.5 Length = 514 Score = 398 bits (1023), Expect = e-109, Method: Compositional matrix adjust. Identities = 199/269 (73%), Positives = 225/269 (83%), Gaps = 5/269 (1%) Query: 1 MSIKIYVPRDSAAIALGANDVAAAIRGEAEKRGVEVNIVRNGSRGMFWLEPLVEVETGQG 60 MSI+++VPRDSAA+ALGA+D A A+ EA +RGV++ +VRNGSRG+FWLEPLVEVET QG Sbjct: 1 MSIRLFVPRDSAALALGADDTAVALAAEAARRGVDIELVRNGSRGLFWLEPLVEVETAQG 60 Query: 61 RVAYGPVDPTDVAGLFDAGFLEDATDAFEHPLAQGLTEEIPYLKKQERLTFARVGITDPV 120 RVAYGPV+ DVA LFDA EHPL GLTE+IPYLK QERLTFARVGITDP+ Sbjct: 61 RVAYGPVEADDVAALFDA-----LIHGAEHPLGHGLTEDIPYLKNQERLTFARVGITDPL 115 Query: 121 SLDDYLAHEGYAGLKRAVGMSSEAIVQEVLDSGLRGRGGAAFPTGIKWKTVAAAKAAQKY 180 SL DY AHEG+AGLKRA+ M AIVQEVLDSGLRGRGGAAFPTGIKW+TVA A+AAQKY Sbjct: 116 SLADYQAHEGFAGLKRALSMDGAAIVQEVLDSGLRGRGGAAFPTGIKWRTVALAEAAQKY 175 Query: 181 IVCNADEGDSGTFSDRMVMEDDPFTLIEGMTIAGLAVGATQGYIYVRSEYPHAIAALNEA 240 +VCNADEGDSGT+SDRMVMEDDPF LIEGMTIAGLAVGATQGYIYVRSEYPH+ LN+A Sbjct: 176 VVCNADEGDSGTYSDRMVMEDDPFMLIEGMTIAGLAVGATQGYIYVRSEYPHSFDVLNQA 235 Query: 241 IASASQNGYLGDNVLGSGKAFCLEVRMGA 269 I A G+LG+N+L SGK F L+VR A Sbjct: 236 IRLAEDAGFLGENILASGKCFKLDVRKAA 264 >Q608U7.1 Q608U7_METCA Formate dehydrogenase, beta subunit EC=1.2.1.2 Length = 516 Score = 394 bits (1011), Expect = e-107, Method: Compositional matrix adjust. Identities = 197/267 (73%), Positives = 219/267 (82%), Gaps = 4/267 (1%) Query: 3 IKIYVPRDSAAIALGANDVAAAIRGEAEKRGVEVNIVRNGSRGMFWLEPLVEVETGQGRV 62 I +YVPRDS+A+ LGA VA AI+ EA +RG + +VRNGSRG++WLEPLVEV T GRV Sbjct: 2 ITVYVPRDSSALGLGAERVANAIQLEAARRGTAIKLVRNGSRGLYWLEPLVEVVTPGGRV 61 Query: 63 AYGPVDPTDVAGLFDAGFLEDATDAFEHPLAQGLTEEIPYLKKQERLTFARVGITDPVSL 122 AYGPV P DVAGLF+AGFLE HPL QGLTEEIPYLK QERLTFARVGITDPV L Sbjct: 62 AYGPVRPGDVAGLFEAGFLEGKA----HPLYQGLTEEIPYLKNQERLTFARVGITDPVCL 117 Query: 123 DDYLAHEGYAGLKRAVGMSSEAIVQEVLDSGLRGRGGAAFPTGIKWKTVAAAKAAQKYIV 182 +DYLAH GY GL+ A+ M AIV+EV SGLRGRGGAAFPTGIKWKTV A A QKY+V Sbjct: 118 EDYLAHGGYRGLRNALAMEPAAIVEEVTASGLRGRGGAAFPTGIKWKTVLNAPAGQKYVV 177 Query: 183 CNADEGDSGTFSDRMVMEDDPFTLIEGMTIAGLAVGATQGYIYVRSEYPHAIAALNEAIA 242 CNADEGDSGTFSDRM+ME DPF LIEGMTIAGLAVGATQGYIY+R EYPHA ALN+AI Sbjct: 178 CNADEGDSGTFSDRMIMEGDPFVLIEGMTIAGLAVGATQGYIYLRIEYPHAGVALNQAIE 237 Query: 243 SASQNGYLGDNVLGSGKAFCLEVRMGA 269 +A Q GYLGD++LGSGK F LEVR+GA Sbjct: 238 AAIQAGYLGDDILGSGKRFQLEVRLGA 264