BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0018.p (547 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPG9.1 D8IPG9_HERSS Permease of the major facilitator superfam... 942 0.0 Q8P887.1 Q8P887_XANCP Integral membrane transporter 830 0.0 Q4UVV0.1 Q4UVV0_XANC8 Integral membrane transporter 830 0.0 B0RRT3.1 B0RRT3_XANCB Major facilitator superfamily protein, pro... 830 0.0 F0C3E5.1 F0C3E5_9XANT Major Facilitator Superfamily transporter 828 0.0 >D8IPG9.1 D8IPG9_HERSS Permease of the major facilitator superfamily protein Length = 580 Score = 942 bits (2436), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/548 (86%), Positives = 510/548 (93%), Gaps = 1/548 (0%) Query: 1 MAFDFLQKEHTIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRALGIKESIACAP 60 MAFDFL KEHT+AKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLS+ALG+ IAC Sbjct: 33 MAFDFLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGA 92 Query: 61 DTGFFAQVFSTTCDWKISMLGWMYTMFFVLLGISAAIWGGWLERAGPRKAGVVSALCWCG 120 D GFFAQVFS++CDWKISMLGWMYTMFFVLLGISAA+WGGWLE AGPRKAGVV+A+CWCG Sbjct: 93 DVGFFAQVFSSSCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCG 152 Query: 121 GLLISALGVYTHQIWLMWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFG 180 GLLISALGV THQIWLMWLGSGVIGG+GLGLGYISPVSTLIKWFPDRRGMATGMAIMGFG Sbjct: 153 GLLISALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFG 212 Query: 181 GGALVGSPLADKLMKHFATPTSVGVWETFVAMAVIYFVFMMAGALGYRVPPSGWKPAGWT 240 GGALVG+PLAD MK FATPTSVGVWETFV MAVIYFVFMMAGA GYRVPP+GWKPAGWT Sbjct: 213 GGALVGTPLADAAMKKFATPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWT 272 Query: 241 PP-ATTNSTMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGISSPMLQEVFGGHL 299 PP A +++TMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGI+SPMLQEVFGG L Sbjct: 273 PPVAKSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKL 332 Query: 300 LGVNVGFSDLSIEQKAAIAAIAAGFTGLISLFNIGGRFVWASCSDFFGRKMTYVIFFVLG 359 LGVN+GF+DLS+EQK AIAA+AAGFTGLISLFNIGGRF WASCSDFFGRKMTY IFFVLG Sbjct: 333 LGVNIGFNDLSVEQKTAIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLG 392 Query: 360 FILYVSLPWSAKAGSIALFVGAVCIILSMYGGGFSTVPAYLADLFGTQMVGAIHGRLLTA 419 F+LYVSLPWSAKAG+I LFVGAVCIILSMYGGGF+TVPAYLADLFGTQMVGAIHGRLLTA Sbjct: 393 FVLYVSLPWSAKAGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTA 452 Query: 420 WATAGILGPVVVNYMREYQLSLGMPREQVYNTTMYILAGMLVVGLICNLLVRPVAAKHFM 479 WATAGILGPVVVNYMREYQL+ GMP+ +VYNTTMYILAGML++GLICNLL+RPVAAKHFM Sbjct: 453 WATAGILGPVVVNYMREYQLAQGMPKNEVYNTTMYILAGMLILGLICNLLIRPVAAKHFM 512 Query: 480 TPEELAREKQLAHEKSSSDNTTSLSPTDMALVGRGGNPALIGAAWLAVGIPLIWGISLTL 539 TPEELA EK+LAHEKS++D + DM+ +G GGNP IG AW AVGIPLIWGI+L L Sbjct: 513 TPEELAHEKKLAHEKSAADAAVTAGSGDMSQIGSGGNPVFIGLAWAAVGIPLIWGITLVL 572 Query: 540 QKTAVLFR 547 QK+AVLFR Sbjct: 573 QKSAVLFR 580 >Q8P887.1 Q8P887_XANCP Integral membrane transporter Length = 559 Score = 830 bits (2143), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/543 (78%), Positives = 467/543 (86%) Query: 5 FLQKEHTIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRALGIKESIACAPDTGF 64 L KE +A+PGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLS+ALGI ESIAC D G Sbjct: 17 LLSKERIVARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGITESIACPADMGL 76 Query: 65 FAQVFSTTCDWKISMLGWMYTMFFVLLGISAAIWGGWLERAGPRKAGVVSALCWCGGLLI 124 FA++ +TTCDWKIS L WMYT+FFVLLG SAAIWGGWLERAGPRKAGVVSALCWCGGL+I Sbjct: 77 FARMVATTCDWKISELQWMYTLFFVLLGCSAAIWGGWLERAGPRKAGVVSALCWCGGLVI 136 Query: 125 SALGVYTHQIWLMWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 SA G++ HQIW++WLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA+ Sbjct: 137 SAAGIHFHQIWMLWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAM 196 Query: 185 VGSPLADKLMKHFATPTSVGVWETFVAMAVIYFVFMMAGALGYRVPPSGWKPAGWTPPAT 244 +GSPLAD LM+HFATPTSVGV ETF+ MA +YFVFMMAGA GYRVPPSGW PAGWT P Sbjct: 197 IGSPLADALMRHFATPTSVGVMETFLVMAALYFVFMMAGAFGYRVPPSGWTPAGWTAPVA 256 Query: 245 TNSTMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGISSPMLQEVFGGHLLGVNV 304 +N+ MIT NHVHV KVWGIPQFWL+W VLCLNVSAGIGVIG+SSPMLQEVFGG L+GV+ Sbjct: 257 SNNAMITANHVHVKKVWGIPQFWLLWGVLCLNVSAGIGVIGMSSPMLQEVFGGRLIGVDA 316 Query: 305 GFSDLSIEQKAAIAAIAAGFTGLISLFNIGGRFVWASCSDFFGRKMTYVIFFVLGFILYV 364 GF L Q A+IAAIAAGFTGL+SLFNIGGRF WAS SD GRK TY +FF+LG LY Sbjct: 317 GFGSLDAAQLASIAAIAAGFTGLLSLFNIGGRFFWASMSDKLGRKNTYTLFFLLGICLYA 376 Query: 365 SLPWSAKAGSIALFVGAVCIILSMYGGGFSTVPAYLADLFGTQMVGAIHGRLLTAWATAG 424 + P + G IALFVG CIILSMYGGGF+T+PAYLADLFGTQMVGAIHGRLLTAWATAG Sbjct: 377 AAPSAGGVGGIALFVGIFCIILSMYGGGFATIPAYLADLFGTQMVGAIHGRLLTAWATAG 436 Query: 425 ILGPVVVNYMREYQLSLGMPREQVYNTTMYILAGMLVVGLICNLLVRPVAAKHFMTPEEL 484 ILGPVVV YMREYQL+ G P QVYNTTMYILAGMLV+GLICNLLVRPVAA+HFMTP+EL Sbjct: 437 ILGPVVVGYMREYQLAHGSPPSQVYNTTMYILAGMLVLGLICNLLVRPVAARHFMTPDEL 496 Query: 485 AREKQLAHEKSSSDNTTSLSPTDMALVGRGGNPALIGAAWLAVGIPLIWGISLTLQKTAV 544 AREKQLAHEK L+P DMA +G GGNPAL+ AWLAVG+P+ +GI +TLQK V Sbjct: 497 AREKQLAHEKVDRSGQAVLAPEDMARIGHGGNPALVAFAWLAVGVPMAFGIWVTLQKAFV 556 Query: 545 LFR 547 LF Sbjct: 557 LFH 559 >Q4UVV0.1 Q4UVV0_XANC8 Integral membrane transporter Length = 559 Score = 830 bits (2143), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/543 (78%), Positives = 467/543 (86%) Query: 5 FLQKEHTIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRALGIKESIACAPDTGF 64 L KE +A+PGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLS+ALGI ESIAC D G Sbjct: 17 LLSKERIVARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGITESIACPADMGL 76 Query: 65 FAQVFSTTCDWKISMLGWMYTMFFVLLGISAAIWGGWLERAGPRKAGVVSALCWCGGLLI 124 FA++ +TTCDWKIS L WMYT+FFVLLG SAAIWGGWLERAGPRKAGVVSALCWCGGL+I Sbjct: 77 FARMVATTCDWKISELQWMYTLFFVLLGCSAAIWGGWLERAGPRKAGVVSALCWCGGLVI 136 Query: 125 SALGVYTHQIWLMWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 SA G++ HQIW++WLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA+ Sbjct: 137 SAAGIHFHQIWMLWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAM 196 Query: 185 VGSPLADKLMKHFATPTSVGVWETFVAMAVIYFVFMMAGALGYRVPPSGWKPAGWTPPAT 244 +GSPLAD LM+HFATPTSVGV ETF+ MA +YFVFMMAGA GYRVPPSGW PAGWT P Sbjct: 197 IGSPLADALMRHFATPTSVGVMETFLVMAALYFVFMMAGAFGYRVPPSGWTPAGWTAPVA 256 Query: 245 TNSTMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGISSPMLQEVFGGHLLGVNV 304 +N+ MIT NHVHV KVWGIPQFWL+W VLCLNVSAGIGVIG+SSPMLQEVFGG L+GV+ Sbjct: 257 SNNAMITANHVHVKKVWGIPQFWLLWGVLCLNVSAGIGVIGMSSPMLQEVFGGRLIGVDA 316 Query: 305 GFSDLSIEQKAAIAAIAAGFTGLISLFNIGGRFVWASCSDFFGRKMTYVIFFVLGFILYV 364 GF L Q A+IAAIAAGFTGL+SLFNIGGRF WAS SD GRK TY +FF+LG LY Sbjct: 317 GFGSLDAAQLASIAAIAAGFTGLLSLFNIGGRFFWASMSDKLGRKNTYTLFFLLGICLYA 376 Query: 365 SLPWSAKAGSIALFVGAVCIILSMYGGGFSTVPAYLADLFGTQMVGAIHGRLLTAWATAG 424 + P + G IALFVG CIILSMYGGGF+T+PAYLADLFGTQMVGAIHGRLLTAWATAG Sbjct: 377 AAPSAGGVGGIALFVGIFCIILSMYGGGFATIPAYLADLFGTQMVGAIHGRLLTAWATAG 436 Query: 425 ILGPVVVNYMREYQLSLGMPREQVYNTTMYILAGMLVVGLICNLLVRPVAAKHFMTPEEL 484 ILGPVVV YMREYQL+ G P QVYNTTMYILAGMLV+GLICNLLVRPVAA+HFMTP+EL Sbjct: 437 ILGPVVVGYMREYQLAHGSPPSQVYNTTMYILAGMLVLGLICNLLVRPVAARHFMTPDEL 496 Query: 485 AREKQLAHEKSSSDNTTSLSPTDMALVGRGGNPALIGAAWLAVGIPLIWGISLTLQKTAV 544 AREKQLAHEK L+P DMA +G GGNPAL+ AWLAVG+P+ +GI +TLQK V Sbjct: 497 AREKQLAHEKVDRSGQAVLAPEDMARIGHGGNPALVAFAWLAVGVPMAFGIWVTLQKAFV 556 Query: 545 LFR 547 LF Sbjct: 557 LFH 559 >B0RRT3.1 B0RRT3_XANCB Major facilitator superfamily protein, probable Length = 559 Score = 830 bits (2143), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/543 (78%), Positives = 467/543 (86%) Query: 5 FLQKEHTIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRALGIKESIACAPDTGF 64 L KE +A+PGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLS+ALGI ESIAC D G Sbjct: 17 LLSKERIVARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGITESIACPADMGL 76 Query: 65 FAQVFSTTCDWKISMLGWMYTMFFVLLGISAAIWGGWLERAGPRKAGVVSALCWCGGLLI 124 FA++ +TTCDWKIS L WMYT+FFVLLG SAAIWGGWLERAGPRKAGVVSALCWCGGL+I Sbjct: 77 FARMVATTCDWKISELQWMYTLFFVLLGCSAAIWGGWLERAGPRKAGVVSALCWCGGLVI 136 Query: 125 SALGVYTHQIWLMWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 SA G++ HQIW++WLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA+ Sbjct: 137 SAAGIHFHQIWMLWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAM 196 Query: 185 VGSPLADKLMKHFATPTSVGVWETFVAMAVIYFVFMMAGALGYRVPPSGWKPAGWTPPAT 244 +GSPLAD LM+HFATPTSVGV ETF+ MA +YFVFMMAGA GYRVPPSGW PAGWT P Sbjct: 197 IGSPLADALMRHFATPTSVGVMETFLVMAALYFVFMMAGAFGYRVPPSGWTPAGWTAPVA 256 Query: 245 TNSTMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGISSPMLQEVFGGHLLGVNV 304 +N+ MIT NHVHV KVWGIPQFWL+W VLCLNVSAGIGVIG+SSPMLQEVFGG L+GV+ Sbjct: 257 SNNAMITANHVHVKKVWGIPQFWLLWGVLCLNVSAGIGVIGMSSPMLQEVFGGRLIGVDA 316 Query: 305 GFSDLSIEQKAAIAAIAAGFTGLISLFNIGGRFVWASCSDFFGRKMTYVIFFVLGFILYV 364 GF L Q A+IAAIAAGFTGL+SLFNIGGRF WAS SD GRK TY +FF+LG LY Sbjct: 317 GFGSLDAAQLASIAAIAAGFTGLLSLFNIGGRFFWASMSDKLGRKNTYTLFFLLGICLYA 376 Query: 365 SLPWSAKAGSIALFVGAVCIILSMYGGGFSTVPAYLADLFGTQMVGAIHGRLLTAWATAG 424 + P + G IALFVG CIILSMYGGGF+T+PAYLADLFGTQMVGAIHGRLLTAWATAG Sbjct: 377 AAPSAGGVGGIALFVGIFCIILSMYGGGFATIPAYLADLFGTQMVGAIHGRLLTAWATAG 436 Query: 425 ILGPVVVNYMREYQLSLGMPREQVYNTTMYILAGMLVVGLICNLLVRPVAAKHFMTPEEL 484 ILGPVVV YMREYQL+ G P QVYNTTMYILAGMLV+GLICNLLVRPVAA+HFMTP+EL Sbjct: 437 ILGPVVVGYMREYQLAHGSPPSQVYNTTMYILAGMLVLGLICNLLVRPVAARHFMTPDEL 496 Query: 485 AREKQLAHEKSSSDNTTSLSPTDMALVGRGGNPALIGAAWLAVGIPLIWGISLTLQKTAV 544 AREKQLAHEK L+P DMA +G GGNPAL+ AWLAVG+P+ +GI +TLQK V Sbjct: 497 AREKQLAHEKVDRSGQAVLAPEDMARIGHGGNPALVAFAWLAVGVPMAFGIWVTLQKAFV 556 Query: 545 LFR 547 LF Sbjct: 557 LFH 559 >F0C3E5.1 F0C3E5_9XANT Major Facilitator Superfamily transporter Length = 558 Score = 828 bits (2140), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/543 (78%), Positives = 467/543 (86%) Query: 5 FLQKEHTIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRALGIKESIACAPDTGF 64 L KE IA+PGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLS+ALGI E+IAC D G Sbjct: 16 LLSKERIIARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGITEAIACPADMGL 75 Query: 65 FAQVFSTTCDWKISMLGWMYTMFFVLLGISAAIWGGWLERAGPRKAGVVSALCWCGGLLI 124 FA++ +TTCDWKIS L WMYT+FFVLLG SAAIWGGWLERAGPRKAGVVSALCWCGGL+I Sbjct: 76 FARMVATTCDWKISELQWMYTLFFVLLGCSAAIWGGWLERAGPRKAGVVSALCWCGGLVI 135 Query: 125 SALGVYTHQIWLMWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 SA G++ HQIW++WLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA+ Sbjct: 136 SAAGIHFHQIWMLWLGSGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAM 195 Query: 185 VGSPLADKLMKHFATPTSVGVWETFVAMAVIYFVFMMAGALGYRVPPSGWKPAGWTPPAT 244 +GSPLAD LM+HFATPTSVGV ETF+ MA +YFVFMMAGA GYRVPPSGW PAGWT P Sbjct: 196 IGSPLADALMRHFATPTSVGVMETFLVMAALYFVFMMAGAFGYRVPPSGWTPAGWTAPVA 255 Query: 245 TNSTMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGISSPMLQEVFGGHLLGVNV 304 +N+ MIT NHVHVSKVWGIPQFWL+W VLCLNVSAGIGVIG+SSPMLQEVFGG L+GV+V Sbjct: 256 SNNAMITANHVHVSKVWGIPQFWLLWGVLCLNVSAGIGVIGMSSPMLQEVFGGRLIGVDV 315 Query: 305 GFSDLSIEQKAAIAAIAAGFTGLISLFNIGGRFVWASCSDFFGRKMTYVIFFVLGFILYV 364 GF L Q A+IAAIAAGFTGL+SLFNIGGRF WAS SD GRK TY +FFVLG LY Sbjct: 316 GFGSLDPTQLASIAAIAAGFTGLLSLFNIGGRFFWASMSDKLGRKNTYTLFFVLGICLYA 375 Query: 365 SLPWSAKAGSIALFVGAVCIILSMYGGGFSTVPAYLADLFGTQMVGAIHGRLLTAWATAG 424 + P + G IALF G CIILSMYGGGF+T+PAYLADLFGTQMVGAIHGRLLTAWATAG Sbjct: 376 AAPSAGDVGGIALFAGIFCIILSMYGGGFATIPAYLADLFGTQMVGAIHGRLLTAWATAG 435 Query: 425 ILGPVVVNYMREYQLSLGMPREQVYNTTMYILAGMLVVGLICNLLVRPVAAKHFMTPEEL 484 ILGPVVV YMREYQL+ G P QVYNTTMYILAGMLV+GLICNLLVRPVAA+HFMTP+EL Sbjct: 436 ILGPVVVGYMREYQLAHGSPPSQVYNTTMYILAGMLVLGLICNLLVRPVAARHFMTPDEL 495 Query: 485 AREKQLAHEKSSSDNTTSLSPTDMALVGRGGNPALIGAAWLAVGIPLIWGISLTLQKTAV 544 AREKQLAHEK L P MA +G GGNPAL+ AWLAVGIP+++GI +TLQK V Sbjct: 496 AREKQLAHEKVDRSGHGVLPPEQMARIGHGGNPALVAFAWLAVGIPMLFGIWVTLQKAFV 555 Query: 545 LFR 547 LF Sbjct: 556 LFH 558