BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0032.p (915 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPK2.1 D8IPK2_HERSS Lytic murein transglycosylase protein EC=2... 803 0.0 F1VTY3.1 F1VTY3_9BURK Membrane-bound lytic murein transglycosyla... 653 0.0 A6SXA1.1 A6SXA1_JANMA Membrane-bound lytic murein transglycosyla... 650 0.0 A4G7G6.1 A4G7G6_HERAR Putative lytic transglycosylase EC=3.2.1.- 641 0.0 C3X4E4.1 C3X4E4_OXAFO Membrane-bound lytic Murein transglycosyla... 566 e-159 >D8IPK2.1 D8IPK2_HERSS Lytic murein transglycosylase protein EC=2.4.1.129 Length = 509 Score = 803 bits (2075), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/445 (86%), Positives = 413/445 (92%), Gaps = 2/445 (0%) Query: 1 LAIATLFSLGTPLLAHANDISIYPAAFNAINPNDPSSALPGMEDIDIWARIRKGFGIPDL 60 LAIA LF G PLL++ANDISIYPA FNAINP +ALPGM DIDIW RIRKGFGIPDL Sbjct: 8 LAIAALFCAGAPLLSYANDISIYPAPFNAINPELAGNALPGMNDIDIWTRIRKGFGIPDL 67 Query: 61 ENPLVDNQTQWYSSRPDYIQRTTVRASRYLFHVVQELEKRGMPTELALLPFIESAFNPQA 120 +N LV++QTQWYSSRPDYIQRTTVRASRYLFHVVQELEKRGMPTELALLPFIESAFNP+A Sbjct: 68 DNSLVESQTQWYSSRPDYIQRTTVRASRYLFHVVQELEKRGMPTELALLPFIESAFNPEA 127 Query: 121 LSTAKAAGMWQFIPSTGRDYNLKQNLFTDERRDVLASTDAALTYLQKLYGMFGDWQLALA 180 LSTAKAAGMWQFIPSTGRDYNLKQN+FTDERRDVLASTDAALTYLQKLYGMFGDWQLALA Sbjct: 128 LSTAKAAGMWQFIPSTGRDYNLKQNMFTDERRDVLASTDAALTYLQKLYGMFGDWQLALA 187 Query: 181 AYNWGEGSVQRAVNRNLAAGLPIDFNTLSAQMPNETRNYVPKLQAVKNIIAVPGEFGIEL 240 AYNWGEGSVQRAVNRNLAAG+PIDFNTLSAQMPNETRNYVPKLQAVKNIIA P F I L Sbjct: 188 AYNWGEGSVQRAVNRNLAAGMPIDFNTLSAQMPNETRNYVPKLQAVKNIIANPAAFDIAL 247 Query: 241 PKVDNQPYFVTIGKTRNIDVKVAAQLAELSLDEFKALNPQFNRPVIIGGDDTKILLPESN 300 PKVDNQPYFVTIGKTRNIDVKVAAQLAELSLDEFKALNPQFNRPVIIGG+DTKILLPESN Sbjct: 248 PKVDNQPYFVTIGKTRNIDVKVAAQLAELSLDEFKALNPQFNRPVIIGGEDTKILLPESN 307 Query: 301 AEKFKTNISKFTQALSSWTSHTVSSARERIETIASRFGTTPDVIRSVNQIPPKMVLKAGS 360 AEKFK N+SK+TQA S+WT+HTVSSARERIETIAS+FGTTP+VIRSVNQIPP+MVLKAGS Sbjct: 308 AEKFKANMSKWTQAFSTWTAHTVSSARERIETIASKFGTTPEVIRSVNQIPPRMVLKAGS 367 Query: 361 MILVPKTETS--MEADITPEMANSARLAVAPDVPDFKRIYVKVGKRDTLASIAGRYRVSV 418 ILVPKTE + ++ D+TPE+A++ARLA+APDVP+ +RIYVK GKRDTLA IA RYRV+V Sbjct: 368 TILVPKTEETAALDTDLTPEIADNARLAIAPDVPETRRIYVKAGKRDTLAGIASRYRVTV 427 Query: 419 VQIKQWNSLRHDTLANGQSLQLQVP 443 QIK+WN L+ DTLA GQSLQLQVP Sbjct: 428 AQIKEWNGLKRDTLAAGQSLQLQVP 452 >F1VTY3.1 F1VTY3_9BURK Membrane-bound lytic murein transglycosylase D Length = 491 Score = 653 bits (1685), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/469 (66%), Positives = 372/469 (79%), Gaps = 2/469 (0%) Query: 1 LAIATLFSLGTPLLAHANDISIYPAAFN-AINPNDPSSALPGMEDIDIWARIRKGFGIPD 59 L L P + AND+SI P+ + +P+DP + + +E++D+W RIR GFGIPD Sbjct: 9 LTFTAFLLLAAPHASQANDLSISPSITDYTYDPSDPVTQVLAIEELDVWGRIRNGFGIPD 68 Query: 60 LENPLVDNQTQWYSSRPDYIQRTTVRASRYLFHVVQELEKRGMPTELALLPFIESAFNPQ 119 L+NPLV +QT WYS+RP+YIQRTT+RASRYLFHV+QELEKR MPTELALLPFIESAFNP+ Sbjct: 69 LDNPLVLSQTNWYSARPEYIQRTTLRASRYLFHVLQELEKRDMPTELALLPFIESAFNPE 128 Query: 120 ALSTAKAAGMWQFIPSTGRDYNLKQNLFTDERRDVLASTDAALTYLQKLYGMFGDWQLAL 179 A S+AKA+GMWQFIPSTG D+NLKQN+F DERRDVLASTDAALTYLQKL+GMFGDWQLAL Sbjct: 129 AYSSAKASGMWQFIPSTGLDFNLKQNMFKDERRDVLASTDAALTYLQKLHGMFGDWQLAL 188 Query: 180 AAYNWGEGSVQRAVNRNLAAGLPIDFNTLSAQMPNETRNYVPKLQAVKNIIAVPGEFGIE 239 AAYNWGEGSVQRA+ +N A GL DFN+LSA MP ETRNYVPKLQAVKNIIA P FGI Sbjct: 189 AAYNWGEGSVQRAIKKNQANGLATDFNSLSALMPAETRNYVPKLQAVKNIIATPEAFGIT 248 Query: 240 LPKVDNQPYFVTIGKTRNIDVKVAAQLAELSLDEFKALNPQFNRPVIIGGDDTKILLPES 299 LPK DNQPYFVTIG+TR+ID+KVAAQLAE++LDEFK+LNPQFNRPVI G TKILLP+ Sbjct: 249 LPKADNQPYFVTIGRTRDIDLKVAAQLAEITLDEFKSLNPQFNRPVITGSASTKILLPQQ 308 Query: 300 NAEKFKTNISKFTQALSSWTSHTVSSARERIETIASRFGTTPDVIRSVNQIPPKMVLKAG 359 NAE+FK N++++ + LSSW +HTV+ RERIE IA+ F T P V+R VN IPP M LKAG Sbjct: 309 NAERFKINLAQWNRPLSSWMAHTVTK-RERIEAIATLFNTEPQVLRDVNHIPPNMRLKAG 367 Query: 360 SMILVPKTETSMEADITPEMANSARLAVAPDVPDFKRIYVKVGKRDTLASIAGRYRVSVV 419 S ILVPKT + E DIT E+A++A +++ PDVPDF+RI V+VGKRD LASIA RY V+V Sbjct: 368 STILVPKTAKAAETDITAEVADNAVISMEPDVPDFRRIAVRVGKRDNLASIAQRYNVTVA 427 Query: 420 QIKQWNSLRHDTLANGQSLQLQVPYQTPAAAPVXGTATGAGTPGNPCAG 468 Q+K WN L+ DTL +GQ+LQ+QVPY+ A A P AG Sbjct: 428 QVKNWNDLQRDTLRSGQTLQVQVPYRASAKTGQRTVRVAANRPHRKDAG 476 >A6SXA1.1 A6SXA1_JANMA Membrane-bound lytic murein transglycosylase D EC=3.2.1.- Length = 531 Score = 650 bits (1677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/443 (70%), Positives = 368/443 (83%), Gaps = 13/443 (2%) Query: 14 LAHANDISIYPAAFNAI-------NP---NDPSSALPGMEDIDIWARIRKGFGIPDL-EN 62 L+HA+D+S+ P +N + NP NDP S D+D+WARIRKGF IPDL +N Sbjct: 33 LSHASDLSLPP--YNWVQDAALQDNPSLANDPLSEFVVASDVDVWARIRKGFAIPDLTDN 90 Query: 63 PLVDNQTQWYSSRPDYIQRTTVRASRYLFHVVQELEKRGMPTELALLPFIESAFNPQALS 122 LV NQT WYSSRPDYI RTT RAS YL+HVV+ELEKRGMPTELALLPFIESAFNPQA S Sbjct: 91 QLVINQTIWYSSRPDYIGRTTKRASLYLYHVVEELEKRGMPTELALLPFIESAFNPQAYS 150 Query: 123 TAKAAGMWQFIPSTGRDYNLKQNLFTDERRDVLASTDAALTYLQKLYGMFGDWQLALAAY 182 TAKAAGMWQFIPSTGRD+NLKQN+F DERR VLASTDAALTYLQKLYGMFGDWQLALAAY Sbjct: 151 TAKAAGMWQFIPSTGRDFNLKQNMFKDERRSVLASTDAALTYLQKLYGMFGDWQLALAAY 210 Query: 183 NWGEGSVQRAVNRNLAAGLPIDFNTLSAQMPNETRNYVPKLQAVKNIIAVPGEFGIELPK 242 NWGEGSVQRA+ + AAG+ DFN+LSA MP ETRNYVPKLQAVKNIIA P +GI L K Sbjct: 211 NWGEGSVQRAIRKAEAAGVGTDFNSLSAYMPAETRNYVPKLQAVKNIIASPDAYGITLLK 270 Query: 243 VDNQPYFVTIGKTRNIDVKVAAQLAELSLDEFKALNPQFNRPVIIGGDDTKILLPESNAE 302 VDNQPYFV+I KTR+IDVK+AAQLAEL +DEFKALNPQFNRPVI G +T+ILLP+SNAE Sbjct: 271 VDNQPYFVSIAKTRDIDVKLAAQLAELPMDEFKALNPQFNRPVITGSSNTQILLPQSNAE 330 Query: 303 KFKTNISKFTQALSSWTSHTVSSARERIETIASRFGTTPDVIRSVNQIPPKMVLKAGSMI 362 KFK N++K++ ALSSWT+H V++ARERIETIA++F TTP VIR VN IPPKM+LKAGS + Sbjct: 331 KFKANLAKWSHALSSWTAHKVTNARERIETIAAKFHTTPQVIREVNNIPPKMLLKAGSTV 390 Query: 363 LVPKTETSMEADITPEMANSARLAVAPDVPDFKRIYVKVGKRDTLASIAGRYRVSVVQIK 422 LVP+T+ + + DIT E+A++A LA+ PDVPD KRI V V K+DT+ ++A RY+VS+ QIK Sbjct: 391 LVPRTDETAQKDITQEVADNATLAMTPDVPDTKRINVVVKKKDTINTLASRYKVSIAQIK 450 Query: 423 QWNSLRHDTLANGQSLQLQVPYQ 445 WN+L HD LA+GQ L++ VPY+ Sbjct: 451 SWNNLSHDKLASGQKLEIHVPYK 473 >A4G7G6.1 A4G7G6_HERAR Putative lytic transglycosylase EC=3.2.1.- Length = 514 Score = 641 bits (1654), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/463 (67%), Positives = 374/463 (80%), Gaps = 14/463 (3%) Query: 1 LAIATLFSLGTPLLAHA-NDISIYPAAFNAI--------NPN---DPSSALPGMEDIDIW 48 L A++F LG ++HA +D+S+ P ++++ NPN DP S D+D+W Sbjct: 12 LVAASIFLLGISSISHAASDLSL-PYSYSSWAQDAALQDNPNLANDPLSEFVVASDVDVW 70 Query: 49 ARIRKGFGIPDL-ENPLVDNQTQWYSSRPDYIQRTTVRASRYLFHVVQELEKRGMPTELA 107 ARIRKGF IPDL +N LV NQT WYSSRP+YI RTT RAS YL+HVV+ELEKRGMPTELA Sbjct: 71 ARIRKGFAIPDLVDNQLVINQTVWYSSRPEYIGRTTKRASLYLYHVVEELEKRGMPTELA 130 Query: 108 LLPFIESAFNPQALSTAKAAGMWQFIPSTGRDYNLKQNLFTDERRDVLASTDAALTYLQK 167 LLPFIESAFNPQA STAKAAGMWQFIPSTG D+NLKQN+F DERR VLASTDAALTYLQ+ Sbjct: 131 LLPFIESAFNPQAYSTAKAAGMWQFIPSTGLDFNLKQNMFKDERRSVLASTDAALTYLQR 190 Query: 168 LYGMFGDWQLALAAYNWGEGSVQRAVNRNLAAGLPIDFNTLSAQMPNETRNYVPKLQAVK 227 LYGMFGDWQLALAAYNWGEGSVQRA+ + AAG+ DFN+LSA MP ET+NYVPKLQAVK Sbjct: 191 LYGMFGDWQLALAAYNWGEGSVQRAIKKAEAAGVGTDFNSLSAYMPAETKNYVPKLQAVK 250 Query: 228 NIIAVPGEFGIELPKVDNQPYFVTIGKTRNIDVKVAAQLAELSLDEFKALNPQFNRPVII 287 NIIA P +GI L KVDNQPYFV++ KTR+IDVK+AAQLAEL ++EFKALNPQFNRPVI Sbjct: 251 NIIATPDAYGISLLKVDNQPYFVSVAKTRDIDVKLAAQLAELPMEEFKALNPQFNRPVIT 310 Query: 288 GGDDTKILLPESNAEKFKTNISKFTQALSSWTSHTVSSARERIETIASRFGTTPDVIRSV 347 G +T+ILLP+ NAEKFK N++K++ ALSSWT+H +++ARERIET+A+RF TTP VIR V Sbjct: 311 GSSNTQILLPQGNAEKFKINLAKWSHALSSWTAHKITNARERIETVAARFHTTPQVIREV 370 Query: 348 NQIPPKMVLKAGSMILVPKTETSMEADITPEMANSARLAVAPDVPDFKRIYVKVGKRDTL 407 N IPPKMVLKAGS ILVP+ E + DIT E+A++ARLA+APD PD KRI V V K+D+ Sbjct: 371 NNIPPKMVLKAGSTILVPRMEGMAQKDITQEVADNARLAMAPDAPDSKRINVTVKKQDSF 430 Query: 408 ASIAGRYRVSVVQIKQWNSLRHDTLANGQSLQLQVPYQTPAAA 450 SIA RY+V++ QIK WN+LR D LA+GQ L+L +P++ + A Sbjct: 431 TSIANRYKVTIAQIKNWNNLRGDKLAHGQKLELHIPFRIASKA 473 >C3X4E4.1 C3X4E4_OXAFO Membrane-bound lytic Murein transglycosylase D Length = 558 Score = 567 bits (1460), Expect = e-159, Method: Compositional matrix adjust. Identities = 274/467 (58%), Positives = 346/467 (74%), Gaps = 19/467 (4%) Query: 1 LAIATLFSLGTPLLAHANDISI--YP-----AAFNA-----------INPNDPSSALPGM 42 LA+A F++ P L A DI++ Y AAF++ + DP + + + Sbjct: 12 LALAGCFTVTAPALVQARDITLPKYSKDAQLAAFHSATDLNVTGNARFDEEDPLTEILSI 71 Query: 43 EDIDIWARIRKGFGIPDLENPLVDNQTQWYSSRPDYIQRTTVRASRYLFHVVQELEKRGM 102 ++D+W RIR GFGIPDL+N LV+N WYS RP+Y QRTT R S+YLFH+VQELEKR M Sbjct: 72 NEVDVWGRIRSGFGIPDLDNRLVENHMNWYSKRPEYFQRTTQRGSKYLFHIVQELEKRNM 131 Query: 103 PTELALLPFIESAFNPQALSTAKAAGMWQFIPSTGRDYNLKQNLFTDERRDVLASTDAAL 162 PTELALLPFIESA+NP A S AKA G+WQFIPSTGR Y+L QN F DERRD+L+ST+AAL Sbjct: 132 PTELALLPFIESAYNPHARSIAKAEGLWQFIPSTGRHYDLGQNAFRDERRDILSSTEAAL 191 Query: 163 TYLQKLYGMFGDWQLALAAYNWGEGSVQRAVNRNLAAGLPIDFNTLSAQMPNETRNYVPK 222 TYLQKL+ MFGDWQLALA+YNWGEGSV RA+ + AG P+ FN++SA MP ETRNYVPK Sbjct: 192 TYLQKLHDMFGDWQLALASYNWGEGSVMRAIKKAERAGKPVTFNSISAYMPAETRNYVPK 251 Query: 223 LQAVKNIIAVPGEFGIELPKVDNQPYFVTIGKTRNIDVKVAAQLAELSLDEFKALNPQFN 282 LQAVKN+IA P +GI+LP V+NQPYFVTIGKTR+IDVKVAA+LAE+SLDEF+ALNPQF Sbjct: 252 LQAVKNLIANPRRYGIDLPSVENQPYFVTIGKTRDIDVKVAAKLAEMSLDEFRALNPQFG 311 Query: 283 RPVIIGGDDTKILLPESNAEKFKTNISKFTQALSSWTSHTVSSARERIETIASRFGTTPD 342 VI GG++ KILLP NAEKF+ N+S++TQ LSSWT++ V+ +RE++E IA+RF T+PD Sbjct: 312 PYVIAGGNEVKILLPGENAEKFRRNLSRWTQPLSSWTAYQVTGSREKVEDIAARFNTSPD 371 Query: 343 VIRSVNQIPPKMVLKAGSMILVPKTETSMEADITPEMANSARLAVAPDVPDFKRIYVKVG 402 +IR N IP + VLK GS ILVPKT + + DI PE+ +ARL D+P + + V V Sbjct: 372 LIRQANNIPSRAVLKFGSAILVPKTAAN-DRDIAPELVENARLVWERDLPSTRLVRVPVK 430 Query: 403 KRDTLASIAGRYRVSVVQIKQWNSLRHDTLANGQSLQLQVPYQTPAA 449 K LASIA RYRVSV ++K WN + DT G L++ VPY++ ++ Sbjct: 431 KPVKLASIAKRYRVSVAELKSWNKISGDTAGKGTILKVHVPYRSASS 477