BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0185.p (487 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q0KBJ3.1 Q0KBJ3_CUPNH NAD-dependent aldehyde dehydrogenase EC=1.... 603 e-170 Q13LU1.1 Q13LU1_BURXL Aldehyde dehydrogenase (Acceptor) EC=1.2.99.3 594 e-167 C3MI58.1 C3MI58_RHISN Putative aldehyde dehydrogenase 588 e-166 B9Z0M6.1 B9Z0M6_9NEIS Aldehyde dehydrogenase (NAD(+)) EC=1.2.1.3 582 e-164 Q140J5.1 Q140J5_BURXL Aldehyde dehydrogenase (Acceptor) EC=1.2.99.3 568 e-160 >Q0KBJ3.1 Q0KBJ3_CUPNH NAD-dependent aldehyde dehydrogenase EC=1.2.1.3 Length = 493 Score = 603 bits (1554), Expect = e-170, Method: Compositional matrix adjust. Identities = 290/485 (59%), Positives = 363/485 (74%), Gaps = 1/485 (0%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 + I W D + G+W +S++PF+G+ A++PRG D +A AA A + P WS+++AT Sbjct: 7 LFINNEWVDPSRGQWFESLDPFTGEAWAEIPRGTREDVDRAAQAAAAAMKGP-WSKMSAT 65 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 RG LL KL LIE + L ++E NGK +EV GQV VA++FYYYAG+ADKI G+V Sbjct: 66 NRGMLLYKLAGLIEENIDLLTEVEARDNGKLRSEVRGQVGYVAKYFYYYAGMADKIQGAV 125 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 VP++KP VFNY R EP+GVV ITPWNS L LTAWK+APAL GN IV KPSE TS LL Sbjct: 126 VPMDKPKVFNYTRLEPVGVVGTITPWNSSLLLTAWKVAPALCAGNAIVAKPSEHTSASLL 185 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 ELA L +AGFPPGV NVV+G+G ++G L+ HP V IAFTGGD GG++V AAA +FK Sbjct: 186 ELARLFVKAGFPPGVFNVVTGFGRDVGEPLVEHPLVPMIAFTGGDEGGRRVNLAAAAHFK 245 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 K+TLELGGKS NIVF DAD A NG I G+F A GQTCMAGSRLL++ SIHD+FV RL+ Sbjct: 246 KVTLELGGKSPNIVFDDADLTNAANGVITGIFSAGGQTCMAGSRLLLQESIHDEFVDRLV 305 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 + A++G+PA S+ Q+GP+ATR Q+EK++ YI IA++DGATC GG SGA YG GQ Sbjct: 306 AITSKAKLGDPARSDVQMGPVATRPQFEKVVDYIRIAREDGATCAFGGKTRSGADYGAGQ 365 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FV PTIFTNV NDMRIA+EEVFGP+LSV+ F ++AL IAND FGLAA VWT LH+A Sbjct: 366 FVEPTIFTNVTNDMRIAQEEVFGPVLSVLKFKDEDDALRIANDIRFGLAAGVWTKSLHRA 425 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQPNK 480 +Y S+R++AGTVW+NNYR+TSFTTPFGGYK SG+GREGG E +E+M+ KSVW++T Sbjct: 426 MYMSERLQAGTVWINNYRSTSFTTPFGGYKDSGLGREGGTEAVKEFMETKSVWVSTDLEM 485 Query: 481 QNAFV 485 + FV Sbjct: 486 PDPFV 490 >Q13LU1.1 Q13LU1_BURXL Aldehyde dehydrogenase (Acceptor) EC=1.2.99.3 Length = 491 Score = 594 bits (1531), Expect = e-167, Method: Compositional matrix adjust. Identities = 284/477 (59%), Positives = 373/477 (78%), Gaps = 1/477 (0%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 + I W D SG W ++ +PF+G+ A++PR + DA +AV AA KA P WS L+A+ Sbjct: 6 LFIDNEWVDPHSGAWFETDDPFTGEPWAEIPRADPTDADRAVRAAEKALEGP-WSTLSAS 64 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 +RG L+ KLG LIERDA LA IE NGK +V GQ++ +A+++YY+ GLADKI G+V Sbjct: 65 ERGMLMYKLGALIERDAEHLATIESRDNGKLFRDVLGQMKYMAKYYYYFGGLADKIQGAV 124 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 VPI+KPG+FN++RYEP+GVV++ITPWNS L LT WKMAPAL GNTIV KPSEFTS L Sbjct: 125 VPIDKPGIFNFIRYEPMGVVLSITPWNSSLPLTTWKMAPALCAGNTIVCKPSEFTSASLF 184 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 ELA L EAGFP GV NVV+G+G EIGA+L++HP VA+IAFTGGD G+K+ AAA++ K Sbjct: 185 ELAKLFVEAGFPRGVFNVVTGFGPEIGASLVSHPGVARIAFTGGDEAGRKIYAAAAQHLK 244 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 +++LELGGKS NIVF DAD +QA+NG I+G+F A GQTC+AGSR+L++ SIHD FV R+ Sbjct: 245 RVSLELGGKSPNIVFDDADLDQAVNGVISGIFSATGQTCVAGSRVLLQESIHDAFVERVA 304 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 ++ AA++GNP D +++GPI T+ Q+EKILGYI+IA ++GA CV GG ALSG YG G+ Sbjct: 305 KLTRAAKVGNPLDPASEIGPITTKPQFEKILGYIDIATREGARCVAGGRALSGPGYGAGR 364 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FV PT+F +V NDMRIA+EEVFGP+LS+I F E+A+ I ND FGLAA VWT LH+A Sbjct: 365 FVEPTVFVDVTNDMRIAQEEVFGPVLSIIRFKDEEDAIRIGNDIKFGLAAGVWTNSLHRA 424 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQ 477 + S R++AGTVW+NNYR++SFTTPFGG+K+SG+GREGG+E +E+M+AKSVW+++ Sbjct: 425 MLMSQRLKAGTVWINNYRSSSFTTPFGGFKQSGIGREGGIESVKEFMEAKSVWMSSD 481 >C3MI58.1 C3MI58_RHISN Putative aldehyde dehydrogenase Length = 492 Score = 588 bits (1516), Expect = e-166, Method: Compositional matrix adjust. Identities = 279/486 (57%), Positives = 360/486 (74%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 MLI G W D+A GE ++ P++GDV A +P+G + DA +AV+AA+KA+ S W +LTA+ Sbjct: 6 MLIDGQWADAALGETFETRNPYTGDVWAAIPKGTKEDAERAVEAAHKAFTSGTWPKLTAS 65 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 RG LLR+LGDLI +A RLA IE + NGK I E+ Q++ + QW++Y+ GLADKI G+V Sbjct: 66 DRGHLLRRLGDLIAENAERLARIEVTDNGKLINEMLFQLKYIPQWYHYFGGLADKIEGAV 125 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 +PI+KP FNY R EPLGV V ITPWNSPL L ++K+APALA GNT V KPSEFTS L Sbjct: 126 IPIDKPETFNYTRNEPLGVCVGITPWNSPLLLLSYKLAPALAAGNTFVAKPSEFTSASTL 185 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 E A L +AGFPPGV NVV+G+G ++G L H VAKIAFTG + G+K+ E AA+NFK Sbjct: 186 EFAKLVEQAGFPPGVFNVVTGFGADVGETLTTHKHVAKIAFTGSEGTGRKIGELAARNFK 245 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 K+TLELGGKS +IVFADA+ + A+NG I+G+F A GQTC+AGSRLLVE IHD+ + ++I Sbjct: 246 KVTLELGGKSPHIVFADAEIDNAVNGVISGIFAATGQTCIAGSRLLVESKIHDQVLEKVI 305 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 +A AR+G+P + TQVGP+ T Q EKILGYI+IAK +GA C+LGG S ++ G G Sbjct: 306 ALAKTARMGDPLSTSTQVGPVTTPPQLEKILGYIDIAKGEGAECLLGGARPSNSELGNGW 365 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FV PTIF VRN MRIA+EEVFGP+L+VIPFD+ EEA+ IANDT++GLAA WT D+ + Sbjct: 366 FVEPTIFAGVRNSMRIAQEEVFGPVLAVIPFDTEEEAIHIANDTNYGLAAGFWTQDMRRM 425 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQPNK 480 + S I+AGTVWVN YR S+ +P GGYK SG+GRE G+ Q Y+Q KSV I+T + Sbjct: 426 LRVSAAIQAGTVWVNTYRTISYMSPLGGYKHSGIGRENGMASIQNYLQTKSVMISTAESV 485 Query: 481 QNAFVL 486 N F++ Sbjct: 486 ANPFIM 491 >B9Z0M6.1 B9Z0M6_9NEIS Aldehyde dehydrogenase (NAD(+)) EC=1.2.1.3 Length = 492 Score = 582 bits (1501), Expect = e-164, Method: Compositional matrix adjust. Identities = 278/486 (57%), Positives = 357/486 (73%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 + I G ++ + GEW + P++G+ A++ RGN AD QAV AA +A+ W EL+A+ Sbjct: 6 LFIDGDLREPSGGEWFTTENPYTGEPWAEIARGNAADVEQAVQAAQRAFTQGPWPELSAS 65 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 RG LL +LGDLI A LA IE NGK +E+ Q+ V QWF YY GLADK+ GSV Sbjct: 66 ARGLLLHRLGDLIAEHAEELARIEVRDNGKLFSEMRAQLNYVPQWFRYYGGLADKLQGSV 125 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 +PI+K G FN+ R EPLGVV ITPWNSPL L AWK+APALA G T+V+KPSEFTS + Sbjct: 126 IPIDKKGYFNFTRDEPLGVVAIITPWNSPLMLLAWKLAPALAAGCTVVIKPSEFTSASTV 185 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 LA L SEAG PPGV+NVV+G+GNE+G+ L+ HP V K+ FTG D G++++E AA++FK Sbjct: 186 ALAKLVSEAGIPPGVVNVVTGFGNEVGSELVAHPLVRKVTFTGADSTGRRISEQAARDFK 245 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 ++LELGGKS NI+FADA+ + A+NGAI+G+F A GQTC+AGSRLLV+ SIHD+ V RL+ Sbjct: 246 HVSLELGGKSPNIIFADANLDDAVNGAISGIFAATGQTCIAGSRLLVQDSIHDEIVERLL 305 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 +A AR+G+P D TQVGPI T Q+EK+L YI+IAKQ+GAT VLGG A + G+G Sbjct: 306 ALAKTARMGDPMDPATQVGPITTPPQFEKVLSYIDIAKQEGATLVLGGGAAQRPECGKGW 365 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FV PT+FTNV+NDMRIA+EEVFGP+LS+I F +EA+ IAND FGL A VWT D+ +A Sbjct: 366 FVEPTVFTNVQNDMRIAQEEVFGPVLSIIRFKDEQEAVAIANDVRFGLGAGVWTQDMGRA 425 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQPNK 480 S+RI+AGTVW+N YRA S+ +PFGGYK SG+GRE G++ EY+Q KSVWI T Sbjct: 426 FRMSERIQAGTVWINTYRAVSYMSPFGGYKDSGIGRENGIDAVNEYLQRKSVWINTGAET 485 Query: 481 QNAFVL 486 N FV+ Sbjct: 486 GNPFVI 491 >Q140J5.1 Q140J5_BURXL Aldehyde dehydrogenase (Acceptor) EC=1.2.99.3 Length = 496 Score = 568 bits (1463), Expect = e-160, Method: Compositional matrix adjust. Identities = 275/476 (57%), Positives = 367/476 (77%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 M+IGG SASG W++SI+P++G+ A+VPRG+ DA AV AA KA + AW +L+AT Sbjct: 12 MVIGGERVPSASGVWLESIDPYTGEPWAKVPRGDATDAEAAVSAARKALTTGAWHQLSAT 71 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 QRGALLR+L DLI RD RLA+IE NGK I+EV Q+R +AQ+F+YYAGLADKI G+V Sbjct: 72 QRGALLRRLADLISRDWERLAEIEIRDNGKVISEVGPQIRYLAQYFHYYAGLADKIEGAV 131 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 +P+++PG+ NY R+EP+GVVVAITPWNSPL L +WK+APALA G T+++KPSE TS L Sbjct: 132 IPVDRPGMLNYTRHEPVGVVVAITPWNSPLMLASWKIAPALAAGCTVILKPSEHTSVSSL 191 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 + L EAGFPPGV+NVV+G+G EIG AL++HP VAK+AFTGGD+ GQ V E AA K Sbjct: 192 VFSDLFDEAGFPPGVVNVVTGFGAEIGNALVSHPDVAKVAFTGGDVAGQAVYERAAAGLK 251 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 ++TLELGGKS +IVF DAD + A+ A+ GVF ++GQ C+AGSRL++ IHD+FVARL+ Sbjct: 252 RVTLELGGKSPHIVFDDADLDGALAAAMDGVFSSSGQMCVAGSRLMLHDRIHDEFVARLL 311 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 + ++G P + T +GP+ T++Q+E+IL YI++AKQ+GA C++GG A A+ G G Sbjct: 312 DRVRTLKLGAPMNPATSIGPVTTQAQFERILSYIDVAKQEGARCLVGGVASPEAEGGSGW 371 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FVAPT+F +V+NDMRIAREEVFGP+LS+I F + +EA+ +AND+ +GLA+ +WT D+ +A Sbjct: 372 FVAPTVFGDVKNDMRIAREEVFGPVLSIIRFSTDDEAVHLANDSRYGLASGIWTRDVGRA 431 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITT 476 I +DRI+AGTVWVN YRA S +PFGG KRSG+GRE G E ++Q KS+WI+T Sbjct: 432 ISVADRIQAGTVWVNTYRAVSAASPFGGMKRSGIGRENGQEAIMGFLQTKSIWIST 487