BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0183.p (403 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q1LFR4.1 Q1LFR4_RALME Acyl-CoA transferase/L-carnitine dehydrata... 493 e-137 C6WH96.1 C6WH96_ACTMD L-carnitine dehydratase/bile acid-inducibl... 481 e-133 Q46RC8.1 Q46RC8_CUPPJ L-carnitine dehydratase/bile acid-inducibl... 478 e-132 Q0JZ32.1 Q0JZ32_CUPNH Predicted acyl-CoA transferase/carnitine d... 471 e-131 B3RC31.1 B3RC31_CUPTR Putative CoA-transferase; caiB/baiF CoA-tr... 470 e-130 >Q1LFR4.1 Q1LFR4_RALME Acyl-CoA transferase/L-carnitine dehydratase, CaiB Length = 414 Score = 493 bits (1268), Expect = e-137, Method: Compositional matrix adjust. Identities = 245/401 (61%), Positives = 305/401 (76%), Gaps = 6/401 (1%) Query: 1 MNKLLEGVTVLDLTNVLSGPFTGYQMALLGANVIKVETPGAGDLARQLGADSDLNKEKMG 60 M K L + VLDLTNVL+GPF +Q+A +GA VIKVETPG GDLARQLGAD++LN++ MG Sbjct: 16 MQKPLRNIRVLDLTNVLAGPFCCHQLAHMGAEVIKVETPGTGDLARQLGADAELNRKLMG 75 Query: 61 TSFLAQNAGKRSISLNLKSAKGKEVLRRLAGNADVILENFRPGVMDRLGVGYNALKDEFP 120 SFLAQN GKRSI++NLK A+GKEV R+L +ADV++ENFRPGVM RLG+GY+ LK P Sbjct: 76 VSFLAQNPGKRSITINLKHARGKEVFRKLVQSADVVVENFRPGVMTRLGLGYDELKLVNP 135 Query: 121 RLVYCAISGFGQTGPLADAPAYDQIIQGRSGVMSITGDEQSAPLRVGYPVCDTIGGMTAA 180 RL+YCAISGFGQ GPL+D PAYDQIIQG +GVMSITGD Q+AP RVGYPV DTIGGMTAA Sbjct: 136 RLIYCAISGFGQDGPLSDLPAYDQIIQGMAGVMSITGDPQTAPYRVGYPVSDTIGGMTAA 195 Query: 181 FAIASALVSRNNTGKGCFIDVSMLDSVMVTMGWIVSNQLIAGRSPVPMGNDNFTASPSGA 240 F+IA++L T +G F+DVSML++ +VTMGW+VSN L+AG+ P PMGN+N TASPSG Sbjct: 196 FSIAASLADTERT-EGYFLDVSMLEATLVTMGWVVSNHLVAGKDPAPMGNENMTASPSGT 254 Query: 241 FRTGDGLLNIAANKQEQFEILCDLLGRSDLKTDPRFAEREIRKTNRKALSEILEEELRRG 300 FRTGDG LNIAANKQEQFE +C ++GR +L TDPRFAER+ R NR AL+ LE EL + Sbjct: 255 FRTGDGPLNIAANKQEQFEAVCRVVGRPELATDPRFAERQSRLANRAALTAELEAELAKK 314 Query: 301 DAAEWERKFNQAGVPAGQVLSVLDALTQDQVQHRGLLMKVLFNKEDLDQT-QEITLTRSG 359 A +W + N+AGVPAG VL V D L QV+ RG++ E++ ++I L R+G Sbjct: 315 SATDWWQLLNEAGVPAGPVLKVPDTLALPQVRDRGMIGAF----ENVPGVGRDIRLLRTG 370 Query: 360 FTIDGEQTGVRHGPPRLGQHTDEILLATGYTPANISNLREE 400 F ++G+ V PP+LG+HTD+IL GY A I L++E Sbjct: 371 FKVNGQAPSVDTPPPQLGEHTDDILGELGYDAAAIDTLKQE 411 >C6WH96.1 C6WH96_ACTMD L-carnitine dehydratase/bile acid-inducible protein F Length = 407 Score = 481 bits (1237), Expect = e-133, Method: Compositional matrix adjust. Identities = 236/399 (59%), Positives = 296/399 (74%), Gaps = 2/399 (0%) Query: 5 LEGVTVLDLTNVLSGPFTGYQMALLGANVIKVETPGAGDLARQLGADSDLNKEKMGTSFL 64 L GV VLDL+NVL+GP+ GYQ+ALLGA+V+KVE PG GDLARQLGA ++LN+ ++G SFL Sbjct: 11 LTGVRVLDLSNVLAGPYAGYQLALLGADVVKVEVPGVGDLARQLGASAELNRRRLGASFL 70 Query: 65 AQNAGKRSISLNLKSAKGKEVLRRLAGNADVILENFRPGVMDRLGVGYNALKDEFPRLVY 124 AQNA KRS++LNLKS++GKEVLRRL +ADV++ENFRPGV++RLG G++AL++ PRLVY Sbjct: 71 AQNAQKRSLTLNLKSSRGKEVLRRLVQSADVLVENFRPGVLERLGFGWDALRELNPRLVY 130 Query: 125 CAISGFGQTGPLADAPAYDQIIQGRSGVMSITGDEQSAPLRVGYPVCDTIGGMTAAFAIA 184 CAISGFGQTGPL PAYDQIIQG SG+MS+TG +APLR GYP+ D +GG+ AAFA++ Sbjct: 131 CAISGFGQTGPLRAKPAYDQIIQGYSGMMSVTGTTGTAPLRAGYPIADVLGGLAAAFAVS 190 Query: 185 SALVSRNNTGKGCFIDVSMLDSVMVTMGWIVSNQLIAGRSPVPMGNDNFTASPSGAFRTG 244 SALV R TG GC IDVSML++ + MGW+VSN LIAG++P P+GNDN TA+PSG FRT Sbjct: 191 SALVGRERTGVGCSIDVSMLETAVTAMGWVVSNHLIAGQAPRPLGNDNGTAAPSGTFRTS 250 Query: 245 DGLLNIAANKQEQFEILCDLLGRSDLKTDPRFAEREIRKTNRKALSEILEEELRRGDAAE 304 DG LNIAANKQEQFE+LC LGR +L DPRFAERE RK +R L+ LE L + AA Sbjct: 251 DGDLNIAANKQEQFELLCAALGRPELVADPRFAERESRKAHRAQLTAELEVALTKESAAH 310 Query: 305 WERKFNQAGVPAGQVLSVLDALTQDQVQHRGLLMKVLFNKEDLDQTQEITLTRSGFTIDG 364 WE + AGVPA VLSV + L Q+ RGL+ ++ F L + + + +G +D Sbjct: 311 WEEALSSAGVPAAAVLSVPEVLASPQIVDRGLVHELPFPGGVLPEP--LRVLGNGIRVDD 368 Query: 365 EQTGVRHGPPRLGQHTDEILLATGYTPANISNLREEGVV 403 + PP LG+HTD +L GY I+ LREEG V Sbjct: 369 RPSTPSLPPPVLGEHTDSLLAELGYAAEEIAALREEGSV 407 >Q46RC8.1 Q46RC8_CUPPJ L-carnitine dehydratase/bile acid-inducible protein F EC=2.8.3.16 Length = 399 Score = 478 bits (1229), Expect = e-132, Method: Compositional matrix adjust. Identities = 248/404 (61%), Positives = 304/404 (75%), Gaps = 6/404 (1%) Query: 1 MNKLLEGVTVLDLTNVLSGPFTGYQMALLGANVIKVETPGAGDLARQLGADSDLNKEKMG 60 M K L V VLDLTNVL+GPF +Q+A +GA VIKVETPG GDLARQLGAD+DLN+ MG Sbjct: 1 MQKPLRHVRVLDLTNVLAGPFCCHQLAHMGAEVIKVETPGTGDLARQLGADADLNQRLMG 60 Query: 61 TSFLAQNAGKRSISLNLKSAKGKEVLRRLAGNADVILENFRPGVMDRLGVGYNALKDEFP 120 SFLAQN GK+SI+LNLK A+GKEV R+L +ADV++ENFRPGVM RLG+GY+ LK + P Sbjct: 61 VSFLAQNPGKQSITLNLKHARGKEVFRKLVQSADVVVENFRPGVMARLGLGYDVLKQDNP 120 Query: 121 RLVYCAISGFGQTGPLADAPAYDQIIQGRSGVMSITGDEQSAPLRVGYPVCDTIGGMTAA 180 RL+YCAISGFGQ GPL+D PAYDQIIQG SGVMSITGD ++AP RVGYPV DTIGG+TAA Sbjct: 121 RLIYCAISGFGQDGPLSDLPAYDQIIQGMSGVMSITGDAETAPYRVGYPVSDTIGGITAA 180 Query: 181 FAIASALVSRNNTGKGCFIDVSMLDSVMVTMGWIVSNQLIAGRSPVPMGNDNFTASPSGA 240 FAIA++L T +G FIDVSML++ + TMGW+VSN LIAG++P PMGN+NFTASPSG Sbjct: 181 FAIAASLADHQRT-EGYFIDVSMLEATLATMGWVVSNHLIAGKAPAPMGNENFTASPSGT 239 Query: 241 FRTGDGLLNIAANKQEQFEILCDLLGRSDLKTDPRFAEREIRKTNRKALSEILEEELRRG 300 FRTGDGLLNIAANKQEQFE +C ++GR +L D RFA R+ R NR AL++ LE EL + Sbjct: 240 FRTGDGLLNIAANKQEQFEAVCRVVGRLELIADERFAARQARLANRAALTQALEAELEKK 299 Query: 301 DAAEWERKFNQAGVPAGQVLSVLDALTQDQVQHRGLLMKVLFNKEDLDQT-QEITLTRSG 359 A EW N+AGVPAG VL V L Q QV+ RG++ D+ ++I + R+G Sbjct: 300 PANEWWALLNEAGVPAGPVLGVPQTLEQPQVRDRGMIGTF----ADVPGVGRDIRVVRTG 355 Query: 360 FTIDGEQTGVRHGPPRLGQHTDEILLATGYTPANISNLREEGVV 403 F ++ E V PP+LG+HT +IL GY+ A+I LR+E V Sbjct: 356 FKLNQEAPSVDTPPPQLGEHTQQILAGLGYSEADIDTLRQERAV 399 >Q0JZ32.1 Q0JZ32_CUPNH Predicted acyl-CoA transferase/carnitine dehydratase EC=5.1.99.- Length = 412 Score = 471 bits (1213), Expect = e-131, Method: Compositional matrix adjust. Identities = 241/403 (59%), Positives = 298/403 (73%), Gaps = 4/403 (0%) Query: 1 MNKLLEGVTVLDLTNVLSGPFTGYQMALLGANVIKVETPGAGDLARQLGADSDLNKEKMG 60 M K L + VLDLTNVL+GPF +Q+A LGA VIKVETPG GDLARQLGAD++LN+ MG Sbjct: 14 MKKPLRHIRVLDLTNVLAGPFCCHQLAHLGAEVIKVETPGTGDLARQLGADAELNQRLMG 73 Query: 61 TSFLAQNAGKRSISLNLKSAKGKEVLRRLAGNADVILENFRPGVMDRLGVGYNALKDEFP 120 SFLAQN GK+S++LNLK A+GKEV R+L +ADV++ENFRPGVMDRLG+GY LK + P Sbjct: 74 VSFLAQNPGKQSVTLNLKHARGKEVFRKLVQSADVLVENFRPGVMDRLGLGYETLKQDNP 133 Query: 121 RLVYCAISGFGQTGPLADAPAYDQIIQGRSGVMSITGDEQSAPLRVGYPVCDTIGGMTAA 180 RL+YCAISGFGQ GPLA PAYDQIIQG +GVMSITGD QSAPLRVGYPV DTIGG+TAA Sbjct: 134 RLIYCAISGFGQDGPLAGLPAYDQIIQGMAGVMSITGDAQSAPLRVGYPVSDTIGGLTAA 193 Query: 181 FAIASALVSRNNTGKGCFIDVSMLDSVMVTMGWIVSNQLIAGRSPVPMGNDNFTASPSGA 240 A+++AL T +G F+DVSML++ + TMGW+VSN LIAG+ P PMGN+N TASPSG Sbjct: 194 LAVSAALADHQRT-EGYFVDVSMLEATLATMGWVVSNHLIAGKVPAPMGNENMTASPSGT 252 Query: 241 FRTGDGLLNIAANKQEQFEILCDLLGRSDLKTDPRFAEREIRKTNRKALSEILEEELRRG 300 FRT DGLLNIAANKQEQFE +C +LGR +L DPRFA+R+ R NR L++ LE EL + Sbjct: 253 FRTADGLLNIAANKQEQFEAVCRVLGRPELAADPRFAQRQARLANRGELTQALEAELAKK 312 Query: 301 DAAEWERKFNQAGVPAGQVLSVLDALTQDQVQHRGLLMKVLFNKEDLDQTQEITLTRSGF 360 A EW +AGVPAG VL V L QV+ RG++ + + ++I + R+GF Sbjct: 313 PATEWWPLLTEAGVPAGPVLDVPQTLAHPQVRERGMIGEF---ADAPGVGRDIRVVRTGF 369 Query: 361 TIDGEQTGVRHGPPRLGQHTDEILLATGYTPANISNLREEGVV 403 ++ E V PP LGQHT ++L + GY+ A+I L EE + Sbjct: 370 KLNREAPAVDTPPPELGQHTRQVLASLGYSDADIDQLSEERAI 412 >B3RC31.1 B3RC31_CUPTR Putative CoA-transferase; caiB/baiF CoA-transferase family EC=2.8.3.16 Length = 399 Score = 470 bits (1210), Expect = e-130, Method: Compositional matrix adjust. Identities = 253/403 (62%), Positives = 301/403 (74%), Gaps = 4/403 (0%) Query: 1 MNKLLEGVTVLDLTNVLSGPFTGYQMALLGANVIKVETPGAGDLARQLGADSDLNKEKMG 60 M K L + VLDLTNVL+GPF +Q+A +GA VIKVETPG GDLARQLGAD+DLN+ MG Sbjct: 1 MQKPLRNIRVLDLTNVLAGPFCCHQLAHMGAEVIKVETPGTGDLARQLGADADLNQRLMG 60 Query: 61 TSFLAQNAGKRSISLNLKSAKGKEVLRRLAGNADVILENFRPGVMDRLGVGYNALKDEFP 120 SFLAQN GK+SI++NLK A+GKEV R+L ADV++ENFRPGVMDRLG+GY+ LK + P Sbjct: 61 VSFLAQNPGKQSITINLKHARGKEVFRKLVRGADVVVENFRPGVMDRLGLGYDTLKQDNP 120 Query: 121 RLVYCAISGFGQTGPLADAPAYDQIIQGRSGVMSITGDEQSAPLRVGYPVCDTIGGMTAA 180 RL+YCAISGFGQ GPLA PAYDQIIQG SGVMSITGD Q+AP RVGYPV DTIGG+TAA Sbjct: 121 RLIYCAISGFGQDGPLAGLPAYDQIIQGMSGVMSITGDAQTAPYRVGYPVSDTIGGLTAA 180 Query: 181 FAIASALVSRNNTGKGCFIDVSMLDSVMVTMGWIVSNQLIAGRSPVPMGNDNFTASPSGA 240 FA+A++L T +G FIDVSML++ + TMGW+VSN LIAGR PVPMGN+N TASPSG Sbjct: 181 FAVAASLADHQRT-EGYFIDVSMLEATLATMGWVVSNHLIAGRDPVPMGNENMTASPSGT 239 Query: 241 FRTGDGLLNIAANKQEQFEILCDLLGRSDLKTDPRFAEREIRKTNRKALSEILEEELRRG 300 FRTGDGLLNIAANKQEQFE +C ++GR +L TD RFA R+ R NR AL+ LE EL R Sbjct: 240 FRTGDGLLNIAANKQEQFEAVCRVVGRPELATDERFARRQARLANRAALTAALEAELARK 299 Query: 301 DAAEWERKFNQAGVPAGQVLSVLDALTQDQVQHRGLLMKVLFNKEDLDQTQEITLTRSGF 360 A EW N AGVPAG VLSV D L+ QV+ RG++ N + ++I + R+GF Sbjct: 300 PATEWWPLLNDAGVPAGPVLSVPDTLSHPQVRDRGMI-GAFANAPGVG--RDIRVVRTGF 356 Query: 361 TIDGEQTGVRHGPPRLGQHTDEILLATGYTPANISNLREEGVV 403 ++ E V PP LGQHT EIL GY+ A+I L EE V Sbjct: 357 KLNREAPAVDTPPPELGQHTREILGQLGYSDADIQQLTEERAV 399