BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0151.p (241 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value E1MJ21.1 E1MJ21_9GAMM 3-hydroxyacyl-CoA dehydrogenase NAD-binding 197 7e-49 F1ZAH1.1 F1ZAH1_9SPHN 3-hydroxyacyl-CoA dehydrogenase 197 1e-48 D3P260.1 D3P260_AZOS1 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 196 3e-48 B8EKE8.1 B8EKE8_METSB 3-hydroxyacyl-CoA dehydrogenase NAD-binding 186 4e-45 Q2RUT5.1 Q2RUT5_RHORT 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 184 1e-44 >E1MJ21.1 E1MJ21_9GAMM 3-hydroxyacyl-CoA dehydrogenase NAD-binding Length = 779 Score = 197 bits (502), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 104/247 (42%), Positives = 148/247 (59%), Gaps = 8/247 (3%) Query: 2 MERKNWTDLEKFVIRGQRAFMQLKYAEAPVVAAAFGLTLGGGCELMMHCDVTLSHSELNA 61 + ++W + + + +GQ+ + LKYA PVV A GL LGGGCE+++HCD +H+EL Sbjct: 534 IHSQDWPAVGQLIKQGQQTYKALKYAPFPVVGAPSGLALGGGCEILLHCDAIQAHAELYI 593 Query: 62 GFPELNVGIVPGWGGCTQLI-------LRTGGDAASIERAFKSVVSTRISSSAAEAVELG 114 G E+ VG+VPGWGGC + + R GG I +AF+++ ++S SAAEA E+ Sbjct: 594 GLVEVGVGLVPGWGGCKEYLRRWLEFARRPGGPMPGIAQAFETIGMAKVSKSAAEAKEML 653 Query: 115 VLRATDPIIMNRDRLLAQAVQQARSLIELPYHAPASKSITLGGAKARNSLLAAVQPLRQS 174 L TD I MN+DRLLA A +A L+ Y P S S L GA AR ++ A+ L+ + Sbjct: 654 FLSTTDGITMNKDRLLADAKSKALRLVP-GYMPPKSSSYQLPGASARAAMDVAINNLKMA 712 Query: 175 GALSDNDWAIVSELATIFSGGESAEEVTLSEIDLSVLERTAFMRLASRPATLERMKHMLA 234 G ++D D I +LA + SGG+ L+E L LE AF+ L +P TL R++H+L Sbjct: 713 GKITDYDVEISQQLADVLSGGQCDITEPLTEDGLLNLELNAFLHLVQQPGTLARLEHLLK 772 Query: 235 TGKPLRN 241 TGKPLRN Sbjct: 773 TGKPLRN 779 >F1ZAH1.1 F1ZAH1_9SPHN 3-hydroxyacyl-CoA dehydrogenase Length = 776 Score = 197 bits (501), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 107/242 (44%), Positives = 144/242 (59%), Gaps = 8/242 (3%) Query: 7 WTDLEKFVIRGQRAFMQLKYAEAPVVAAAFGLTLGGGCELMMHCDVTLSHSELNAGFPEL 66 W ++EK V GQ A LKYA PVVAA GL LGGGCE+++H D +H+E G E Sbjct: 536 WGEIEKMVSGGQMALKALKYAPFPVVAAPAGLALGGGCEIVLHADAVQAHAESYIGLVEC 595 Query: 67 NVGIVPGWGGCTQLILR-------TGGDAASIERAFKSVVSTRISSSAAEAVELGVLRAT 119 VG+VPGWGGC +++ R G ++ + F+++ + +S SAAEA++LG LR T Sbjct: 596 GVGLVPGWGGCGEMLARWQAAKGLPKGPVPAVSKVFETISTATVSKSAAEAMDLGFLRPT 655 Query: 120 DPIIMNRDRLLAQAVQQARSLIELPYHAPASKSITLGGAKARNSLLAAVQPLRQSGALSD 179 D I MNRDRLLA A +A +L E Y PA + L GA + +L AV R G + Sbjct: 656 DGITMNRDRLLADAKARALALAE-GYQPPAPPTYRLPGAGGKAALELAVAGFRARGMATP 714 Query: 180 NDWAIVSELATIFSGGESAEEVTLSEIDLSVLERTAFMRLASRPATLERMKHMLATGKPL 239 +D + LA + +GGE+ T++E DL LER AF+ L P T R++HML TGKPL Sbjct: 715 HDAVVAGHLADVLTGGEADLVDTVAEGDLLALERKAFLALVRHPGTQNRIEHMLKTGKPL 774 Query: 240 RN 241 RN Sbjct: 775 RN 776 >D3P260.1 D3P260_AZOS1 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 766 Score = 196 bits (498), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 107/246 (43%), Positives = 145/246 (58%), Gaps = 7/246 (2%) Query: 2 MERKNWTDLEKFVIRGQRAFMQLKYAEAPVVAAAFGLTLGGGCELMMHCDVTLSHSELNA 61 +ER ++ L FV RGQR+F L++A PVV AAFGL LGGGCEL++HCD ++H+EL A Sbjct: 522 IERGDFAGLRSFVARGQRSFQALRHAPFPVVGAAFGLALGGGCELLLHCDRIVAHAELTA 581 Query: 62 GFPELNVGIVPGWGGCTQLILR------TGGDAASIERAFKSVVSTRISSSAAEAVELGV 115 G PE+NVG++P WGGC Q +LR G A R F V + ++SSSA +A G+ Sbjct: 582 GLPEVNVGLIPAWGGCAQRLLRAMSDDGVKGPVACPVRVFDGVAAAKLSSSALDAHADGI 641 Query: 116 LRATDPIIMNRDRLLAQAVQQARSLIELPYHAPASKSITLGGAKARNSLLAAVQPLRQSG 175 LRA+D I+MNR LL +A +A L Y P I G SL+ + RQ+G Sbjct: 642 LRASDLIVMNRAHLLHRARDEAVRLAR-GYSPPGPAEIMSPGLTGLASLMNGIHGERQAG 700 Query: 176 ALSDNDWAIVSELATIFSGGESAEEVTLSEIDLSVLERTAFMRLASRPATLERMKHMLAT 235 +SD D A+ + L+ + +GG + +SE + LE M LA T R++HML T Sbjct: 701 RISDADVAVRTVLSRVLTGGGADATRPVSEDTIYALELDGVMELAQTATTKSRIEHMLKT 760 Query: 236 GKPLRN 241 GKPLRN Sbjct: 761 GKPLRN 766 >B8EKE8.1 B8EKE8_METSB 3-hydroxyacyl-CoA dehydrogenase NAD-binding Length = 773 Score = 186 bits (471), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 102/242 (42%), Positives = 140/242 (57%), Gaps = 8/242 (3%) Query: 7 WTDLEKFVIRGQRAFMQLKYAEAPVVAAAFGLTLGGGCELMMHCDVTLSHSELNAGFPEL 66 W++LE V +GQ + LKYA PVV A G+ LGGGCE+++HCD +H+E G E+ Sbjct: 533 WSELENLVSQGQTVYRMLKYAPFPVVGAPSGMALGGGCEILLHCDAVQAHAETYVGLVEV 592 Query: 67 NVGIVPGWGGCTQLILR-------TGGDAASIERAFKSVVSTRISSSAAEAVELGVLRAT 119 VG++PGWGGC +++ R G I R F+ V + ++ SAAEA EL LR Sbjct: 593 GVGLIPGWGGCKEMLQRWASLGRLPKGPMPPIARVFEIVGTATVAKSAAEAKELLFLRPG 652 Query: 120 DPIIMNRDRLLAQAVQQARSLIELPYHAPASKSITLGGAKARNSLLAAVQPLRQSGALSD 179 D I MNRDRLLA A +A +L + Y P + L G A +L A ++G + Sbjct: 653 DGITMNRDRLLADAKAKALTLAD-NYAPPQPIVLNLPGPSAATALKMAADSFFRTGKATA 711 Query: 180 NDWAIVSELATIFSGGESAEEVTLSEIDLSVLERTAFMRLASRPATLERMKHMLATGKPL 239 +D + + LA + SGGE+ + E L LER +FMRL PA+L R++HML TGKPL Sbjct: 712 HDLVVSAALARVLSGGETDVMLESDEDRLLRLERDSFMRLVRDPASLARVEHMLETGKPL 771 Query: 240 RN 241 RN Sbjct: 772 RN 773 >Q2RUT5.1 Q2RUT5_RHORT 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 774 Score = 184 bits (466), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 107/242 (44%), Positives = 146/242 (60%), Gaps = 8/242 (3%) Query: 7 WTDLEKFVIRGQRAFMQLKYAEAPVVAAAFGLTLGGGCELMMHCDVTLSHSELNAGFPEL 66 W+++E V GQ+ + L+ A PVV A GL LGGGCE+++HCD +H+E G E+ Sbjct: 534 WSEIETLVAEGQKTYRALREAPFPVVGAPSGLALGGGCEILLHCDAVQAHAESYIGLVEV 593 Query: 67 NVGIVPGWGGCTQLILR-------TGGDAASIERAFKSVVSTRISSSAAEAVELGVLRAT 119 VG+VP WGGCT+++ R G ++ + F++V + ++ SAAEA EL LR Sbjct: 594 GVGLVPAWGGCTEMLHRWSTLGQLPKGPMPALSKVFETVSTATVAKSAAEAKELLFLREG 653 Query: 120 DPIIMNRDRLLAQAVQQARSLIELPYHAPASKSITLGGAKARNSLLAAVQPLRQSGALSD 179 D I MNRDRLLA A +A +L+E Y P + TL GA A+ L AV +++ G + Sbjct: 654 DGITMNRDRLLADAKAKALALVE-GYAPPPRREFTLPGAAAKTGLDMAVASVQRQGKATP 712 Query: 180 NDWAIVSELATIFSGGESAEEVTLSEIDLSVLERTAFMRLASRPATLERMKHMLATGKPL 239 D + LA I SGG++ VTL+E L LERT FM LA RP TL R++ ML TGKPL Sbjct: 713 YDGVVCGALADILSGGDTDITVTLTEDALLELERTHFMALARRPETLARIETMLLTGKPL 772 Query: 240 RN 241 RN Sbjct: 773 RN 774