BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0058.p (305 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IT99.1 D8IT99_HERSS Adenine-specific methylase/methyltransfera... 509 e-142 A6SZR6.1 A6SZR6_JANMA Modification methylase HemK EC=2.1.1.72 480 e-134 A4G4Q6.1 A4G4Q6_HERAR Modification methylase HemK EC=2.1.1.72 476 e-132 F1W392.1 F1W392_9BURK Hypothetical adenine-specific methylase yfcB 439 e-121 C3XAF4.1 C3XAF4_OXAFO Modification methylase HemK 390 e-106 >D8IT99.1 D8IT99_HERSS Adenine-specific methylase/methyltransferase protein EC=2.1.1.- Length = 296 Score = 509 bits (1310), Expect = e-142, Method: Compositional matrix adjust. Identities = 239/294 (81%), Positives = 275/294 (93%) Query: 9 MTPNNFATVRDILRYAITSFNTEKLFFGHGTNNAFDEAAYLILHTLKLPLDQLEPFLDAR 68 MTPNNF+TVRD+LRYA+T FNTE+LFFGHG++NA DEAAYLILHTLKLPLDQL+PFLDAR Sbjct: 1 MTPNNFSTVRDLLRYAVTRFNTEQLFFGHGSSNALDEAAYLILHTLKLPLDQLDPFLDAR 60 Query: 69 LLQGEIDNLLRVIMRRTEDRVPAAYITNEAWLGGYRFFVDERVIVPRSFIAELIPEHFSP 128 LL EI ++RVI RR++DRVPAAYIT+EAWLG YRF+VDERVIVPRSFIAELIP+HFSP Sbjct: 61 LLPDEIAAVMRVIERRSKDRVPAAYITHEAWLGAYRFYVDERVIVPRSFIAELIPQHFSP 120 Query: 129 WVQDPAQVENILDLCTGSGCLPILLADAFPQARVEAVDISPEALQVARRNVDDYELGDRI 188 W+QDP +EN LDLCTGSGCLPILLADAFP A+++AVDIS +AL VAR+NVD+Y+L +RI Sbjct: 121 WIQDPEAIENALDLCTGSGCLPILLADAFPNAQIDAVDISADALAVARKNVDEYQLQERI 180 Query: 189 NLVESDLYTKLPARKYDLIISNPPYVNADSMSKLPQEYLQEPQIALAGGKDGMDLVRKIV 248 NLVESDLYT+LP RKYDLIISNPPYVN+ SM+KLPQEYL+EPQ+ALAGG+DGMDLVRKIV Sbjct: 181 NLVESDLYTQLPLRKYDLIISNPPYVNSGSMAKLPQEYLREPQLALAGGEDGMDLVRKIV 240 Query: 249 KGAAQRLTPNGVLIVEIGNERAYAEAAFPDLELTWVTTSAGDDMVFLVTADQLQ 302 GAA+RLTP GVL+VEIGNERA+AEAAFP+LELTW+TTSAGDDMVFLVTA+QLQ Sbjct: 241 AGAAERLTPEGVLVVEIGNERAFAEAAFPELELTWLTTSAGDDMVFLVTAEQLQ 294 >A6SZR6.1 A6SZR6_JANMA Modification methylase HemK EC=2.1.1.72 Length = 296 Score = 480 bits (1236), Expect = e-134, Method: Compositional matrix adjust. Identities = 225/294 (76%), Positives = 261/294 (88%) Query: 9 MTPNNFATVRDILRYAITSFNTEKLFFGHGTNNAFDEAAYLILHTLKLPLDQLEPFLDAR 68 + PN +T+RD+LRYA+T FNT KLFFGHG+ NA DEAAYLILHTLKLPLD+L+PF DAR Sbjct: 3 IKPNELSTIRDLLRYAVTRFNTAKLFFGHGSTNALDEAAYLILHTLKLPLDKLDPFFDAR 62 Query: 69 LLQGEIDNLLRVIMRRTEDRVPAAYITNEAWLGGYRFFVDERVIVPRSFIAELIPEHFSP 128 LLQ E+D +LRVI +R ++R+PAAYITNE WLGGYRF+VDERVIVPRSFIAELIPE FSP Sbjct: 63 LLQEEVDAVLRVIEQRADERLPAAYITNEGWLGGYRFYVDERVIVPRSFIAELIPEQFSP 122 Query: 129 WVQDPAQVENILDLCTGSGCLPILLADAFPQARVEAVDISPEALQVARRNVDDYELGDRI 188 WV +P +V NIL+LCTGSGCLPI+LADAFP A V+AVDIS +AL+VA+RNV++YELG RI Sbjct: 123 WVSNPDKVNNILELCTGSGCLPIMLADAFPNAHVDAVDISTDALEVAKRNVEEYELGHRI 182 Query: 189 NLVESDLYTKLPARKYDLIISNPPYVNADSMSKLPQEYLQEPQIALAGGKDGMDLVRKIV 248 NL+ESDLY +P K+DLII+NPPYVN+ SM KLP EYL+EPQIALAGG DGMDLVRKIV Sbjct: 183 NLIESDLYANVPEYKFDLIITNPPYVNSGSMDKLPPEYLREPQIALAGGTDGMDLVRKIV 242 Query: 249 KGAAQRLTPNGVLIVEIGNERAYAEAAFPDLELTWVTTSAGDDMVFLVTADQLQ 302 GA QRLTPNG+L+VEIGNER +AEAAFPDL LTW+TTSAGDDMVFL+TADQLQ Sbjct: 243 AGAGQRLTPNGLLMVEIGNEREFAEAAFPDLNLTWLTTSAGDDMVFLITADQLQ 296 >A4G4Q6.1 A4G4Q6_HERAR Modification methylase HemK EC=2.1.1.72 Length = 296 Score = 476 bits (1226), Expect = e-132, Method: Compositional matrix adjust. Identities = 224/292 (76%), Positives = 258/292 (88%) Query: 11 PNNFATVRDILRYAITSFNTEKLFFGHGTNNAFDEAAYLILHTLKLPLDQLEPFLDARLL 70 PN+ +T+RD+LRYA+T FNT KLFFGHG+ NA DEAAYLILHTLKLPLD+L+PF DA LL Sbjct: 5 PNDLSTIRDLLRYAVTRFNTAKLFFGHGSTNALDEAAYLILHTLKLPLDKLDPFFDAHLL 64 Query: 71 QGEIDNLLRVIMRRTEDRVPAAYITNEAWLGGYRFFVDERVIVPRSFIAELIPEHFSPWV 130 Q E+D +LRVI +R ++R+PAAYITNE WLGGY F+VDERVIVPRSFIAELIP+ FSPWV Sbjct: 65 QHEVDAVLRVIEQRADERLPAAYITNEGWLGGYHFYVDERVIVPRSFIAELIPDQFSPWV 124 Query: 131 QDPAQVENILDLCTGSGCLPILLADAFPQARVEAVDISPEALQVARRNVDDYELGDRINL 190 +P ++ NIL+LCTGSGCLPI+LADAFP A+V+AVDIS +AL VARRNVD+YEL DRI L Sbjct: 125 SNPDKITNILELCTGSGCLPIMLADAFPNAQVDAVDISADALAVARRNVDEYELQDRITL 184 Query: 191 VESDLYTKLPARKYDLIISNPPYVNADSMSKLPQEYLQEPQIALAGGKDGMDLVRKIVKG 250 +ESDLYT +P KYDLII+NPPYVN+ SM KLP EYL+EP IALAGG DGMDLVRKIV G Sbjct: 185 IESDLYTHVPENKYDLIITNPPYVNSTSMGKLPPEYLREPHIALAGGDDGMDLVRKIVAG 244 Query: 251 AAQRLTPNGVLIVEIGNERAYAEAAFPDLELTWVTTSAGDDMVFLVTADQLQ 302 A +RLTPNG+L+VEIGNERAYAEAAFP L LTW+TTSAGDDMVFLVTADQLQ Sbjct: 245 AGKRLTPNGLLMVEIGNERAYAEAAFPKLNLTWLTTSAGDDMVFLVTADQLQ 296 >F1W392.1 F1W392_9BURK Hypothetical adenine-specific methylase yfcB Length = 292 Score = 439 bits (1129), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/290 (72%), Positives = 244/290 (84%) Query: 12 NNFATVRDILRYAITSFNTEKLFFGHGTNNAFDEAAYLILHTLKLPLDQLEPFLDARLLQ 71 +F+T+RD+LRYA+T FN KLFFGHG++NA DEAAYLILHTL LPLD+L+PFLDARLL Sbjct: 3 THFSTIRDMLRYAVTRFNEAKLFFGHGSSNALDEAAYLILHTLHLPLDKLDPFLDARLLP 62 Query: 72 GEIDNLLRVIMRRTEDRVPAAYITNEAWLGGYRFFVDERVIVPRSFIAELIPEHFSPWVQ 131 EI+ LL VI RR +R PAAYIT +AWLG Y F+VDERV+VPRSFIAELIP+ FSPWV Sbjct: 63 DEINALLEVIRRRAVERQPAAYITQQAWLGDYHFYVDERVLVPRSFIAELIPDQFSPWVS 122 Query: 132 DPAQVENILDLCTGSGCLPILLADAFPQARVEAVDISPEALQVARRNVDDYELGDRINLV 191 D V NIL+LCTGSGCL I+LADAFP A V+A+DIS +AL VARRNVDDYEL DRI L+ Sbjct: 123 DAESVLNILELCTGSGCLAIMLADAFPNAHVDAIDISADALAVARRNVDDYELQDRITLI 182 Query: 192 ESDLYTKLPARKYDLIISNPPYVNADSMSKLPQEYLQEPQIALAGGKDGMDLVRKIVKGA 251 ES+LY +P +KYDLIISNPPYVN+ SM KLP+EY EP+IALAGG DGMDLVR IV GA Sbjct: 183 ESNLYAAVPDKKYDLIISNPPYVNSASMDKLPKEYQIEPRIALAGGTDGMDLVRNIVAGA 242 Query: 252 AQRLTPNGVLIVEIGNERAYAEAAFPDLELTWVTTSAGDDMVFLVTADQL 301 +RLT G+L+VEIGNERA+AE AFP LELTW+TTSAGDDMVFL TAD+L Sbjct: 243 RERLTRGGLLVVEIGNERAHAELAFPTLELTWMTTSAGDDMVFLATADKL 292 >C3XAF4.1 C3XAF4_OXAFO Modification methylase HemK Length = 302 Score = 390 bits (1003), Expect = e-106, Method: Compositional matrix adjust. Identities = 181/294 (61%), Positives = 240/294 (81%) Query: 12 NNFATVRDILRYAITSFNTEKLFFGHGTNNAFDEAAYLILHTLKLPLDQLEPFLDARLLQ 71 + F+TVRD+LRYA+T FN EKLFFGHG+ NA+DEA +LILHTL LPLD+L+PFLDA+LL Sbjct: 7 STFSTVRDLLRYAVTRFNREKLFFGHGSENAWDEAVFLILHTLSLPLDELDPFLDAKLLP 66 Query: 72 GEIDNLLRVIMRRTEDRVPAAYITNEAWLGGYRFFVDERVIVPRSFIAELIPEHFSPWVQ 131 EI+N++ +I RR ++R+PAAY+TNEA+L GY F+V++ VI+PRSF+AELI E FSPW+ Sbjct: 67 EEIENVVNIIDRRADERIPAAYLTNEAFLQGYSFYVEKGVIIPRSFLAELIVEQFSPWII 126 Query: 132 DPAQVENILDLCTGSGCLPILLADAFPQARVEAVDISPEALQVARRNVDDYELGDRINLV 191 DP V +IL+LCTGSGCL I+LAD F A V+AV++SP AL +A+ N+++Y+L DR+ L Sbjct: 127 DPEGVTDILELCTGSGCLAIMLADVFENATVDAVELSPAALGIAQTNINNYQLKDRVKLH 186 Query: 192 ESDLYTKLPARKYDLIISNPPYVNADSMSKLPQEYLQEPQIALAGGKDGMDLVRKIVKGA 251 +DLY +P ++Y LI++NPPYVN SM LP EY+ EPQ+ALAGG DGMD+VR+IV+ A Sbjct: 187 HADLYDGIPDKQYQLIVTNPPYVNQSSMDDLPPEYMHEPQMALAGGFDGMDIVRRIVRTA 246 Query: 252 AQRLTPNGVLIVEIGNERAYAEAAFPDLELTWVTTSAGDDMVFLVTADQLQHLA 305 ++LT +G+LIVEIGNE A AAFP+LELTW++TS GDD VFL+TA+QL+ L Sbjct: 247 GEKLTDDGLLIVEIGNEAENAIAAFPELELTWLSTSGGDDRVFLLTAEQLKGLG 300