BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0032.p (270 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6SZQ4.1 A6SZQ4_JANMA Pseudouridylate synthase EC=4.2.1.70 443 e-122 A4G4R8.1 A4G4R8_HERAR Putative ribosomal large subunit pseudouri... 429 e-118 D8IU12.1 D8IU12_HERSS RNA pseudouridylate synthase protein EC=4.... 417 e-115 C3X7K3.1 C3X7K3_OXAFO Pseudouridylate synthase 404 e-111 C3X184.1 C3X184_OXAFO Pseudouridylate synthase 404 e-111 >A6SZQ4.1 A6SZQ4_JANMA Pseudouridylate synthase EC=4.2.1.70 Length = 248 Score = 443 bits (1140), Expect = e-122, Method: Compositional matrix adjust. Identities = 215/248 (86%), Positives = 231/248 (93%) Query: 23 MTEPVRLSKRMSELGLCSRREADEWIEKGWVRVDGQVVSVLGSKVLPHQRVSVERQAAAE 82 M EP+RLSKRMSELGLCSRREADEWI +GWVRVDG+VVS LGSKVLP QRV+VERQAAAE Sbjct: 1 MNEPLRLSKRMSELGLCSRREADEWIARGWVRVDGKVVSELGSKVLPTQRVTVERQAAAE 60 Query: 83 QSKRVTILINKPTGFVSGQAEDGYKPAVALVEAATRWKEDQVDTQFHPTQLRSLVPAGRL 142 QSKRVT+LINKP G+VSGQAEDGYKPAVALV A+TRW EDQ TQFHPTQLRSLVPAGRL Sbjct: 61 QSKRVTVLINKPMGYVSGQAEDGYKPAVALVNASTRWSEDQAATQFHPTQLRSLVPAGRL 120 Query: 143 DIDSVGLLVLTQDGRIAKQLIGEDTSVDKEYLVRVQYTKPGKLPDSDLKRLNHGLSLDGK 202 DIDSVGLLVLTQDGRIAK LIGEDTSV+KEYLVRVQY+KPGKLP++DLKRLNHGL LDGK Sbjct: 121 DIDSVGLLVLTQDGRIAKHLIGEDTSVEKEYLVRVQYSKPGKLPEADLKRLNHGLMLDGK 180 Query: 203 ALKPAKVRWQNEDQLSFILNEGKKRQIRRMCELVGLKVVGLKRVRIGGVKLGDLPTGEWR 262 L PAKV+WQNEDQLSFIL EGKKRQIRRMC++VGLKV+GLKRVRIG VKLGDLP G+WR Sbjct: 181 KLLPAKVKWQNEDQLSFILREGKKRQIRRMCDMVGLKVIGLKRVRIGNVKLGDLPVGQWR 240 Query: 263 YLRPDEQF 270 YLR DEQF Sbjct: 241 YLREDEQF 248 >A4G4R8.1 A4G4R8_HERAR Putative ribosomal large subunit pseudouridine synthase Length = 248 Score = 429 bits (1103), Expect = e-118, Method: Compositional matrix adjust. Identities = 210/248 (84%), Positives = 229/248 (92%) Query: 23 MTEPVRLSKRMSELGLCSRREADEWIEKGWVRVDGQVVSVLGSKVLPHQRVSVERQAAAE 82 MTEP+RLSKRMSELGLCSRREADEWI +GWVRVDG+VVS LG+K+LP QRV+VERQAAAE Sbjct: 1 MTEPLRLSKRMSELGLCSRREADEWIARGWVRVDGKVVSELGTKILPTQRVTVERQAAAE 60 Query: 83 QSKRVTILINKPTGFVSGQAEDGYKPAVALVEAATRWKEDQVDTQFHPTQLRSLVPAGRL 142 QSKRVTILINKP G+VSGQAEDGYKPAVALV+A +RWKED TQFHPTQLRSLVPAGRL Sbjct: 61 QSKRVTILINKPMGYVSGQAEDGYKPAVALVKAESRWKEDTSPTQFHPTQLRSLVPAGRL 120 Query: 143 DIDSVGLLVLTQDGRIAKQLIGEDTSVDKEYLVRVQYTKPGKLPDSDLKRLNHGLSLDGK 202 DIDSVGLLVLTQDGRIAK LIGE++SV+KEYLVRVQY KPGKLP++DL+RLNHGL LDGK Sbjct: 121 DIDSVGLLVLTQDGRIAKHLIGENSSVEKEYLVRVQYIKPGKLPEADLQRLNHGLMLDGK 180 Query: 203 ALKPAKVRWQNEDQLSFILNEGKKRQIRRMCELVGLKVVGLKRVRIGGVKLGDLPTGEWR 262 L PA+V+WQNEDQLSFIL EGKKRQIRRMC++VGLKVVGLKRVRIG VKLGDLP GEWR Sbjct: 181 KLLPAQVKWQNEDQLSFILREGKKRQIRRMCDIVGLKVVGLKRVRIGRVKLGDLPVGEWR 240 Query: 263 YLRPDEQF 270 YL EQF Sbjct: 241 YLAEGEQF 248 >D8IU12.1 D8IU12_HERSS RNA pseudouridylate synthase protein EC=4.2.1.70 Length = 248 Score = 417 bits (1073), Expect = e-115, Method: Compositional matrix adjust. Identities = 209/248 (84%), Positives = 232/248 (93%) Query: 23 MTEPVRLSKRMSELGLCSRREADEWIEKGWVRVDGQVVSVLGSKVLPHQRVSVERQAAAE 82 MTEPVRLSKRMSELGLCSRREADEWIEKGWVRVDG VVSVLGSKVLPHQ+V+VERQA+AE Sbjct: 1 MTEPVRLSKRMSELGLCSRREADEWIEKGWVRVDGVVVSVLGSKVLPHQKVTVERQASAE 60 Query: 83 QSKRVTILINKPTGFVSGQAEDGYKPAVALVEAATRWKEDQVDTQFHPTQLRSLVPAGRL 142 Q++RVTIL+NKP G+VSGQAEDGYKPAV LV +RW EDQ + +FHP QL+SLVPAGRL Sbjct: 61 QAQRVTILLNKPMGYVSGQAEDGYKPAVVLVNEQSRWAEDQTEMRFHPRQLKSLVPAGRL 120 Query: 143 DIDSVGLLVLTQDGRIAKQLIGEDTSVDKEYLVRVQYTKPGKLPDSDLKRLNHGLSLDGK 202 DIDSVGLLVLTQDGRIAKQLIGED++VDKEYLVRVQYT+PGKLP+SDLKRLNHGL +DGK Sbjct: 121 DIDSVGLLVLTQDGRIAKQLIGEDSAVDKEYLVRVQYTRPGKLPESDLKRLNHGLIMDGK 180 Query: 203 ALKPAKVRWQNEDQLSFILNEGKKRQIRRMCELVGLKVVGLKRVRIGGVKLGDLPTGEWR 262 L+PAKV WQNEDQL F L EGKKRQIRRMC++VGLKV+GLKRVRIGGVKLG+LPTG+WR Sbjct: 181 PLRPAKVVWQNEDQLRFTLREGKKRQIRRMCDMVGLKVIGLKRVRIGGVKLGELPTGQWR 240 Query: 263 YLRPDEQF 270 YLRPDE+F Sbjct: 241 YLRPDEKF 248 >C3X7K3.1 C3X7K3_OXAFO Pseudouridylate synthase Length = 248 Score = 404 bits (1039), Expect = e-111, Method: Compositional matrix adjust. Identities = 191/248 (77%), Positives = 222/248 (89%) Query: 23 MTEPVRLSKRMSELGLCSRREADEWIEKGWVRVDGQVVSVLGSKVLPHQRVSVERQAAAE 82 M+EPVRLSKRMSELG+ SRREADEWIEKGWV+VDG+VVS LGSKVLPHQ++++E+QA+ E Sbjct: 1 MSEPVRLSKRMSELGISSRREADEWIEKGWVKVDGKVVSQLGSKVLPHQKITIEKQASQE 60 Query: 83 QSKRVTILINKPTGFVSGQAEDGYKPAVALVEAATRWKEDQVDTQFHPTQLRSLVPAGRL 142 QS+RVTILINKP G+VSGQAEDGYKPAVAL+ T WK+D +F P+QLRSLVPAGRL Sbjct: 61 QSRRVTILINKPMGYVSGQAEDGYKPAVALISEDTHWKDDPSKEKFRPSQLRSLVPAGRL 120 Query: 143 DIDSVGLLVLTQDGRIAKQLIGEDTSVDKEYLVRVQYTKPGKLPDSDLKRLNHGLSLDGK 202 DIDSVGLLVLTQDGRIAK LIGE++ DKEYLVRV+YT+PG+LPDS+L L HGL LDGK Sbjct: 121 DIDSVGLLVLTQDGRIAKHLIGENSPTDKEYLVRVKYTRPGRLPDSELNMLRHGLKLDGK 180 Query: 203 ALKPAKVRWQNEDQLSFILNEGKKRQIRRMCELVGLKVVGLKRVRIGGVKLGDLPTGEWR 262 AL PAKV WQN+DQL F+L EGKKRQIRRMCE VGL+V+GLKR+RIG V+LGDLPTG+WR Sbjct: 181 ALLPAKVEWQNDDQLRFVLREGKKRQIRRMCEAVGLRVIGLKRIRIGNVRLGDLPTGQWR 240 Query: 263 YLRPDEQF 270 YLRP+E+F Sbjct: 241 YLRPEEKF 248 >C3X184.1 C3X184_OXAFO Pseudouridylate synthase Length = 249 Score = 404 bits (1038), Expect = e-111, Method: Compositional matrix adjust. Identities = 190/249 (76%), Positives = 224/249 (89%) Query: 22 IMTEPVRLSKRMSELGLCSRREADEWIEKGWVRVDGQVVSVLGSKVLPHQRVSVERQAAA 81 +M+EPVRLSKRMSELG+CSRREADEWIE+GWV+VDG+ VS LGSKVLPHQ++S+E+QA+ Sbjct: 1 MMSEPVRLSKRMSELGICSRREADEWIERGWVKVDGKTVSQLGSKVLPHQKISIEKQASQ 60 Query: 82 EQSKRVTILINKPTGFVSGQAEDGYKPAVALVEAATRWKEDQVDTQFHPTQLRSLVPAGR 141 EQ++RVTILINKP G+VSGQAEDGYKPAV+L+ ATRWK D +F P+QLRSLVPAGR Sbjct: 61 EQARRVTILINKPVGYVSGQAEDGYKPAVSLISEATRWKGDPSKEKFKPSQLRSLVPAGR 120 Query: 142 LDIDSVGLLVLTQDGRIAKQLIGEDTSVDKEYLVRVQYTKPGKLPDSDLKRLNHGLSLDG 201 LDIDSVGLLVLTQDGRIAK+LIGE+++ DKEYLVRV+Y KPGKLP++DL+ L HGL LDG Sbjct: 121 LDIDSVGLLVLTQDGRIAKRLIGENSATDKEYLVRVKYLKPGKLPENDLQLLRHGLKLDG 180 Query: 202 KALKPAKVRWQNEDQLSFILNEGKKRQIRRMCELVGLKVVGLKRVRIGGVKLGDLPTGEW 261 K L PAKV WQN+DQL F+L EGKKRQIRRMCE VGLKV+GLKR+RIG +KLGDLP G+W Sbjct: 181 KPLLPAKVNWQNDDQLRFVLREGKKRQIRRMCEAVGLKVIGLKRIRIGQIKLGDLPPGQW 240 Query: 262 RYLRPDEQF 270 RYLRP+E+F Sbjct: 241 RYLRPEEKF 249