BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0232.p (241 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IW29.1 D8IW29_HERSS Adenylate cyclase protein EC=4.6.1.1 341 5e-92 A6GS32.1 A6GS32_9BURK Adenylate/guanylate cyclase 205 4e-51 C9YD20.1 C9YD20_9BURK Putative uncharacterized protein 203 2e-50 D5CMT7.1 D5CMT7_SIDLE Adenylate/guanylate cyclase with Chase sensor 197 1e-48 Q1GZE1.1 Q1GZE1_METFK Adenylate/guanylate cyclase 170 1e-40 >D8IW29.1 D8IW29_HERSS Adenylate cyclase protein EC=4.6.1.1 Length = 757 Score = 341 bits (874), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 164/235 (69%), Positives = 198/235 (84%) Query: 1 LALVLTLLAGGQVMGMLPAFLTERIDLFFYDMRMRIAKVETDPRIVIVDIDEKSIAEVGR 60 LALVLT LA QVM +LP L ER+DLFFYD+RMR+A+ + DPRIVIVDIDEKSIAE+GR Sbjct: 18 LALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQPDLDPRIVIVDIDEKSIAELGR 77 Query: 61 WPWSRDVVAALIGKMTDSYEAQTVAFDVLFAEPDNSSGYATLESLAHSELKGLPQFGQQL 120 WPWSRDV+A L+ +MT +Y+AQ+V FDV+FAEPD SSGY L LA LK +PQF +QL Sbjct: 78 WPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADGPLKDVPQFARQL 137 Query: 121 QALKPKLDFDARMAAAIQGRPVVMGYNLSNEPSAISKGQLPKPVFTTAALGGRRLDMINW 180 QALKP++D+DAR+A A++G+PVVMGYNLSNE AI+KGQLP P F+ A LGGR LD+ +W Sbjct: 138 QALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPPAFSVADLGGRALDVTHW 197 Query: 181 RAYGANLPQLQEAAESGGFFNPVLDNDGLVRRVPLIAQIGDNFYESLALATARWA 235 RAYGANLPQLQ AA +GGFFNPV D+DGL+R VPL+AQ+G++FYESLALATAR A Sbjct: 198 RAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHFYESLALATARVA 252 >A6GS32.1 A6GS32_9BURK Adenylate/guanylate cyclase Length = 754 Score = 205 bits (522), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 109/241 (45%), Positives = 153/241 (63%), Gaps = 12/241 (4%) Query: 5 LTLLAGGQVMGMLPAFLTERIDLFFYDMRMRIAKV--ETDPRIVIVDIDEKSIAEVGRWP 62 T +A V+G P+ + +R+D YD+R+R E DPRIVIVDIDE+S++EVGRWP Sbjct: 24 FTAVALLHVLGFAPSEVVKRLDYLVYDVRLRAEAQLPELDPRIVIVDIDEQSLSEVGRWP 83 Query: 63 WSRDVVAALIGKMTDSYEAQTVAFDVLFAEPDNSSGYATLESLAHSELKGLPQFGQQLQA 122 WSRDVVA L+ ++TD A V FD++FAEP S L+++ ++ P G QLQ Sbjct: 84 WSRDVVAKLVVELTDRLGAAAVGFDIVFAEPQQSDALLALDTIIENK----PALGSQLQE 139 Query: 123 LKP----KLDFDARMAAAIQGRPVVMGYNLSNEPSAISKGQLPKPVFTTAALGGRRLDMI 178 ++ + D DA++A + RPVV+GY L+ + +A+S G LP +F + LG LD Sbjct: 140 MRSGIQAQFDRDAQLAQVLADRPVVLGYYLNQDATALS-GALPPALFKKSQLGELSLDST 198 Query: 179 NWRAYGANLPQLQEAAESGGFFNPVLDNDGLVRRVPLIAQIGDNFYESLALATARWAXWA 238 +W+ YG N+P LQ+ AE GG+FNP++D DG VR +PLIAQ D +Y+S AL T R A Sbjct: 199 SWQGYGGNIPVLQKNAE-GGYFNPIVDEDGTVRSIPLIAQFNDAYYQSFALGTLRRALGN 257 Query: 239 P 239 P Sbjct: 258 P 258 >C9YD20.1 C9YD20_9BURK Putative uncharacterized protein Length = 749 Score = 203 bits (517), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 104/234 (44%), Positives = 145/234 (61%), Gaps = 1/234 (0%) Query: 1 LALVLTLLAGGQVMGMLPAFLTERIDLFFYDMRMRIAKVET-DPRIVIVDIDEKSIAEVG 59 + L+ + A +G+L + +R+D YD R+R ++ D RIVIVDIDEKS+A VG Sbjct: 13 VTLIPLIFALLHAVGVLQLSVLQRLDDIIYDTRLRATMPKSMDERIVIVDIDEKSLASVG 72 Query: 60 RWPWSRDVVAALIGKMTDSYEAQTVAFDVLFAEPDNSSGYATLESLAHSELKGLPQFGQQ 119 RWPW R+ +A L+ K+ ++ + DV+FAEPD+SSG L+ LA SEL P F + Sbjct: 73 RWPWGRNKLADLVNKLFTEHKIAILGVDVVFAEPDDSSGLQQLKELAKSELSDQPVFLAK 132 Query: 120 LQALKPKLDFDARMAAAIQGRPVVMGYNLSNEPSAISKGQLPKPVFTTAALGGRRLDMIN 179 LQ L P+LD+D A+ + G+P+V+GY +N+P S G LP PVF AL GR L+ Sbjct: 133 LQDLSPRLDYDGVFASVLAGKPIVLGYFFTNDPQGRSSGVLPSPVFLEEALAGRTLEAPE 192 Query: 180 WRAYGANLPQLQEAAESGGFFNPVLDNDGLVRRVPLIAQIGDNFYESLALATAR 233 W AYG+N+ L AA G FN D DG+VR VPL+A + ++ESL+LA R Sbjct: 193 WTAYGSNISSLAAAAPMAGHFNSFTDPDGVVRSVPLVAHYKNAYFESLSLAMFR 246 >D5CMT7.1 D5CMT7_SIDLE Adenylate/guanylate cyclase with Chase sensor Length = 725 Score = 197 bits (500), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 100/220 (45%), Positives = 133/220 (60%), Gaps = 4/220 (1%) Query: 25 IDLFFYDMRMRIA-KVETDPRIVIVDIDEKSIAEVGRWPWSRDVVAALIGKMTDSYEAQT 83 ID YD R+ + + D RIVI+DIDEKS+ E GRWPW R+ +A ++ ++ D Y Sbjct: 16 IDAKLYDYRLLLTLPKKADDRIVILDIDEKSLKEEGRWPWGRNKMAVMMDELFDHYGVAV 75 Query: 84 VAFDVLFAEPDNSSGYATLESLAHSELKGLPQFGQQLQALKPKLDFDARMAAAIQGRPVV 143 V FDV+FAE DNSSG L+ L S+ KG+ QF L +KP L++D A I+ R VV Sbjct: 76 VGFDVVFAEKDNSSGLNVLQDLGRSQFKGVAQFQSVLAQIKPHLEYDKLFAEKIKNRNVV 135 Query: 144 MGYNLSNEPSAISK---GQLPKPVFTTAALGGRRLDMINWRAYGANLPQLQEAAESGGFF 200 +GY SN K G LP+PVF GR + + W +YGANLP+LQ +A G F Sbjct: 136 LGYYFSNSERGHDKSRSGVLPEPVFPAGTFKGRPISFMQWDSYGANLPELQSSAALAGHF 195 Query: 201 NPVLDNDGLVRRVPLIAQIGDNFYESLALATARWAXWAPS 240 NPV+D DG+VRR+P+I + +YESL+LA R A P Sbjct: 196 NPVVDFDGVVRRIPMIVEYDGAYYESLSLAVVRAALGMPK 235 >Q1GZE1.1 Q1GZE1_METFK Adenylate/guanylate cyclase Length = 741 Score = 170 bits (431), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 94/235 (40%), Positives = 136/235 (57%), Gaps = 2/235 (0%) Query: 1 LALVLTLLAGGQVMGMLPAFLTERIDLFFYDMRMRI-AKVETDPRIVIVDIDEKSIAEVG 59 L ++ T + V+G E ++ F YD R+R+ A + D RIVIVDIDE S+ + G Sbjct: 16 LGVLATAILLAHVVGAFRLDFMEAMERFAYDTRIRLLAPEDHDDRIVIVDIDEASLQQEG 75 Query: 60 RWPWSRDVVAALIGKMTDSYEAQTVAFDVLFAEPDNSSGYATLESLAHSELKGLPQFGQQ 119 WPWSR +A L+ + D Y+ + VAFDV+FAE D+SSG A L+++ ++ P++ Sbjct: 76 HWPWSRKRLAQLLDLLFDHYQVRLVAFDVVFAEKDHSSGLAALQAMRQAQFTQRPEWVPL 135 Query: 120 LQALKPKLDFDARMAAAIQGRPVVMGYNLSNEPS-AISKGQLPKPVFTTAALGGRRLDMI 178 + A+ P LD D + A +++GR VV+GY + + G LP PV L GR + + Sbjct: 136 IDAILPALDHDRQFADSMRGRNVVLGYYFRHGTDMGRNIGMLPPPVMQADMLAGRHVAYL 195 Query: 179 NWRAYGANLPQLQEAAESGGFFNPVLDNDGLVRRVPLIAQIGDNFYESLALATAR 233 YGANLP LQ+ A + G FNP D DG+ RRVPL+ YE+L+LA R Sbjct: 196 QASGYGANLPILQQQAAAAGHFNPDPDEDGITRRVPLLVAYQGGMYEALSLAVVR 250