BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0146.p (411 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYM6.1 D8IYM6_HERSS Permease of the major facilitator superfam... 541 e-152 E8WQZ4.1 E8WQZ4_GEOS8 Major facilitator superfamily MFS_1 493 e-137 Q0JY23.1 Q0JY23_CUPNH Putative MFS transporter 462 e-128 Q46QA6.1 Q46QA6_CUPPJ Putative uncharacterized protein 456 e-126 Q1LB12.1 Q1LB12_RALME Putative major facilitator superfamily (MF... 451 e-124 >D8IYM6.1 D8IYM6_HERSS Permease of the major facilitator superfamily protein Length = 423 Score = 541 bits (1395), Expect = e-152, Method: Compositional matrix adjust. Identities = 311/407 (76%), Positives = 347/407 (85%), Gaps = 6/407 (1%) Query: 7 PEQLLHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIPSLFLV 66 P L HH F+LFW ASV STIALQMQIVAVGWQVYQLTHS DLGIVGLVQFIPSL LV Sbjct: 17 PPPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSALDLGIVGLVQFIPSLILV 76 Query: 67 FVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGRAFSKP 126 FVVGHVADR DRR VAR S LVEA+AA LAAGSLGGWL +E IF IV VIGAGRAFSKP Sbjct: 77 FVVGHVADRFDRRNVARVSALVEALAAATLAAGSLGGWLNREIIFVIVAVIGAGRAFSKP 136 Query: 127 TMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVLFVLCS 186 TMSA+LP+LM P LP AVAGSASATQ AIIIGPA+GGFLYVAGP+ VY +SCVLF LCS Sbjct: 137 TMSALLPSLMSPRQLPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCVLFTLCS 196 Query: 187 VLVSMIK------VETPPARRENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATA 240 +L+ +I+ A+ A+L SVFAG+A+IRSKPAIFGAISLD+FAVLLGGATA Sbjct: 197 LLLWLIRRPAQAGAPAAAAKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLGGATA 256 Query: 241 LLPVYAHDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATI 300 LLPV+AHDILHT + GLGLLRSAPA GAL+VA++LAR PL GR+GRTMF+AVG+FGLAT+ Sbjct: 257 LLPVFAHDILHTGAAGLGLLRSAPAAGALAVALWLARRPLGGRVGRTMFVAVGVFGLATM 316 Query: 301 AFGLSQTFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLG 360 FGLS++F +SL AL VLGA+DMISVVVRS+FVQLETPD MRGRVSAVNSVFIGTSNQLG Sbjct: 317 VFGLSRSFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTSNQLG 376 Query: 361 EFESGLTAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRLVDN 407 EFESGLTAAWFGAVPAVLIGG+GTL++V LW+RLFP L+ VDRL Sbjct: 377 EFESGLTAAWFGAVPAVLIGGVGTLLIVLLWVRLFPALYRVDRLTSR 423 >E8WQZ4.1 E8WQZ4_GEOS8 Major facilitator superfamily MFS_1 Length = 428 Score = 493 bits (1268), Expect = e-137, Method: Compositional matrix adjust. Identities = 263/403 (65%), Positives = 319/403 (79%) Query: 2 TSAIAPEQLLHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIP 61 T A +L H FRLFWLA V S++ALQMQ VAVGWQ+Y LT S F LG+VGL QF+P Sbjct: 24 TKAQLQHSVLRHEPFRLFWLARVCSSVALQMQAVAVGWQIYALTGSVFYLGLVGLAQFLP 83 Query: 62 SLFLVFVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGR 121 L VGHVADR+DRR++A ++E +A LLA GS GGWL+KEAI AIVFV G R Sbjct: 84 MFLLTLAVGHVADRYDRRRIAGACQVLEGLALALLALGSYGGWLSKEAILAIVFVAGGLR 143 Query: 122 AFSKPTMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVL 181 AF PTM A++P L+ L+PRA A SASA Q A I GPA+GG LY GP+TVY ++ L Sbjct: 144 AFEGPTMLALVPWLVPQELIPRASAWSASANQTASIAGPALGGLLYALGPTTVYGSAAAL 203 Query: 182 FVLCSVLVSMIKVETPPARRENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATAL 241 F S L+S I+ E P+RRE AT++S+FAGIA+IRS+ I GAISLDLFAVLLGGATAL Sbjct: 204 FFAASFLLSRIRTERAPSRREPATVRSLFAGIAFIRSRQEILGAISLDLFAVLLGGATAL 263 Query: 242 LPVYAHDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATIA 301 LPV+A DILHT +GLGLLR+APA GAL V++FLARNPL+ R+GRTMF++V IFG+ATI Sbjct: 264 LPVFARDILHTGPIGLGLLRAAPAAGALGVSLFLARNPLRHRVGRTMFLSVLIFGVATIV 323 Query: 302 FGLSQTFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLGE 361 FGLS +F +S+ AL+VLGA+D++SVV+R++ VQ+ETPD+MRGRVSAVNS+FIGTSNQLGE Sbjct: 324 FGLSTSFPLSMGALMVLGAADIVSVVIRASLVQIETPDEMRGRVSAVNSMFIGTSNQLGE 383 Query: 362 FESGLTAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRL 404 FESG+TAA FG VPAVLIGGIGT+VVV LW+RLFP+L VDRL Sbjct: 384 FESGVTAALFGTVPAVLIGGIGTVVVVLLWMRLFPRLLEVDRL 426 >Q0JY23.1 Q0JY23_CUPNH Putative MFS transporter Length = 426 Score = 462 bits (1188), Expect = e-128, Method: Compositional matrix adjust. Identities = 247/407 (60%), Positives = 303/407 (74%), Gaps = 3/407 (0%) Query: 3 SAIAPEQLLHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIPS 62 A AP+ + FR +W A + +TI Q+ VAVGWQ+Y LT P LG+VGLVQF+PS Sbjct: 19 QAAAPDSVFRDAVFRRYWFARLCTTIGYQIFTVAVGWQMYDLTRDPLMLGMVGLVQFLPS 78 Query: 63 LFLVFVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGRA 122 + L+ + GHVADR DRR++ R +EA+ A +A SL GW+ IF V +IGA RA Sbjct: 79 VVLILMSGHVADRFDRRRIVRTCQAIEALLAAGMAVASLSGWIDSHHIFVFVALIGATRA 138 Query: 123 FSKPTMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVLF 182 F PT+ A+LP+++ P LPRAVA ++SA Q AIIIGPAIGGF YVAGP VY S LF Sbjct: 139 FETPTLQALLPSVVTPRQLPRAVALASSAGQAAIIIGPAIGGFAYVAGPGVVYGLSATLF 198 Query: 183 VLCSVLVSMIKVETPPARRENA--TLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATA 240 + +VLVS I + A+R A ++++VFAG AYIRS+P + GAISLDLFAVLLGGA A Sbjct: 199 AIAAVLVSGITLRQA-AQRLTAPVSVRTVFAGFAYIRSRPVLLGAISLDLFAVLLGGAVA 257 Query: 241 LLPVYAHDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATI 300 LLP+YA DILHT GLGLLRS+PAVGAL +A++LAR+PL R GR MF AV +FG+AT+ Sbjct: 258 LLPIYARDILHTGPWGLGLLRSSPAVGALVMALWLARHPLNRRAGRIMFGAVALFGVATV 317 Query: 301 AFGLSQTFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLG 360 FG+S +S++ALVVLGASDMISVVVRST VQLETPDDMRGRV AVNSVFIG SNQLG Sbjct: 318 VFGVSTWLPLSMVALVVLGASDMISVVVRSTLVQLETPDDMRGRVGAVNSVFIGASNQLG 377 Query: 361 EFESGLTAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRLVDN 407 EFESG+TAA G V AV++GG+GTL+VVALW+RLFP L DRL D+ Sbjct: 378 EFESGVTAALLGPVGAVILGGVGTLLVVALWMRLFPALAARDRLHDH 424 >Q46QA6.1 Q46QA6_CUPPJ Putative uncharacterized protein Length = 415 Score = 456 bits (1173), Expect = e-126, Method: Compositional matrix adjust. Identities = 244/407 (59%), Positives = 301/407 (73%), Gaps = 1/407 (0%) Query: 2 TSAIAPEQLLHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIP 61 T+A A + + SFR FW A + +TI Q+ VAVGWQ+Y LT F LG+VGLVQF+P Sbjct: 7 TTAEASDGVFGDASFRRFWFARLCTTIGYQIFTVAVGWQMYDLTRDAFMLGLVGLVQFLP 66 Query: 62 SLFLVFVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGR 121 S+ L+ + GH+ADR DRR++ R +EA+ A +A SL G + E IF V +IGA R Sbjct: 67 SVALILMSGHMADRFDRRRIVRTCQALEALIAVAMAVSSLSGRINPEHIFVFVALIGATR 126 Query: 122 AFSKPTMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVL 181 AF PT+ A+LP+++ LPRAVA S+SA Q AIIIGPAIGGF YVAGP VY S L Sbjct: 127 AFETPTLQALLPSVVTQRQLPRAVALSSSAGQAAIIIGPAIGGFAYVAGPGVVYALSATL 186 Query: 182 FVLCSVLVSMIKVETPPAR-RENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATA 240 FV+ ++LVS + + P R ++K++FAG AYIRS+P + GAISLDLFAVLLGGATA Sbjct: 187 FVIAAILVSGLTLRQPVQRLTAPVSVKTLFAGFAYIRSRPVLLGAISLDLFAVLLGGATA 246 Query: 241 LLPVYAHDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATI 300 LLP+YA DILHT GLGLLRSAPA+GAL A++LA +PL R G+ MF AV +FG AT+ Sbjct: 247 LLPIYARDILHTGPWGLGLLRSAPAIGALVTALWLAHHPLNRRAGKVMFGAVALFGAATL 306 Query: 301 AFGLSQTFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLG 360 FG+S +S+ ALVVLGASDMISVVVRST VQL+TPDDMRGRV AVNSVFIG SNQLG Sbjct: 307 VFGVSHWLPLSMAALVVLGASDMISVVVRSTLVQLDTPDDMRGRVGAVNSVFIGASNQLG 366 Query: 361 EFESGLTAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRLVDN 407 EFESG+TAA G V AV++GG+GTL+VVA+W+RLFP L H DRL D+ Sbjct: 367 EFESGVTAALLGPVGAVILGGVGTLLVVAVWMRLFPALTHRDRLHDH 413 >Q1LB12.1 Q1LB12_RALME Putative major facilitator superfamily (MFS) transporter Length = 419 Score = 451 bits (1159), Expect = e-124, Method: Compositional matrix adjust. Identities = 249/410 (60%), Positives = 303/410 (73%), Gaps = 1/410 (0%) Query: 3 SAIAPEQLLHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIPS 62 +A P+ + +FR FW A + +TIA Q+ VAVGWQ+Y LT PF LG+VGLVQF+PS Sbjct: 8 AADEPQTVFRDPAFRHFWFARLCTTIAYQIFTVAVGWQMYDLTRDPFMLGMVGLVQFLPS 67 Query: 63 LFLVFVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGRA 122 + L+ + GHVADR DRR V R ++EA+ A L+AA S GW+T E IF V IG RA Sbjct: 68 IVLLLMSGHVADRFDRRIVVRTCQVLEALIAALMAAASFSGWVTSEHIFLFVAAIGGCRA 127 Query: 123 FSKPTMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVLF 182 F PT+ A+LP+++ LPRAVA S+SA Q AIIIGPA+GGF YVAGP VY S LF Sbjct: 128 FETPTLQALLPSVVTSRQLPRAVALSSSAGQTAIIIGPALGGFAYVAGPGVVYSISAALF 187 Query: 183 VLCSVLVSMIKVETPPAR-RENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATAL 241 + ++LV+ +K+ R A+LK++FAG AYIRS + GA+SLDLFAVLLGGATAL Sbjct: 188 AIAAILVTTLKLRQAAQRMTAQASLKTLFAGFAYIRSHQVLLGAVSLDLFAVLLGGATAL 247 Query: 242 LPVYAHDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATIA 301 LP+YA DILHT GLGLLRSAPA+GAL+ A++LARNPL R+GR MF AV IFGLAT+ Sbjct: 248 LPIYARDILHTGPWGLGLLRSAPAIGALTTALWLARNPLNRRVGRVMFTAVAIFGLATMV 307 Query: 302 FGLSQTFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLGE 361 FG+S+ +S+ ALVVLGASDMISVVVR T VQL+TPDDMRGRV AVNSVFIG SNQLGE Sbjct: 308 FGVSKWLPLSMAALVVLGASDMISVVVRQTLVQLDTPDDMRGRVGAVNSVFIGASNQLGE 367 Query: 362 FESGLTAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRLVDNTGKK 411 FESG+TAA G V AVL+GG+GTL+VV W+RLFP L DRL D+ K Sbjct: 368 FESGVTAALLGPVGAVLLGGVGTLIVVVAWMRLFPNLTERDRLHDHHPAK 417