BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0041.p (269 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY55.1 D8IY55_HERSS Diguanylate cyclase/phosphodiesterase with... 278 5e-73 Q3M5I8.1 Q3M5I8_ANAVT Putative diguanylate cyclase (GGDEF domain) 155 6e-36 B2J9X3.1 B2J9X3_NOSP7 Diguanylate cyclase 145 5e-33 B5ZPN4.1 B5ZPN4_RHILW Diguanylate cyclase 145 7e-33 A8FZK2.1 A8FZK2_SHESH Conserved hypothetical signaling protein 137 1e-30 >D8IY55.1 D8IY55_HERSS Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor domain protein Length = 573 Score = 278 bits (711), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 137/232 (59%), Positives = 180/232 (77%), Gaps = 1/232 (0%) Query: 3 IARSVAEN-SGNFVSYRDGDNREQLAAFAPVPRTSWMVVNVTPLNALNAEVRSIRNKIIL 61 I S+A+ +F++Y D AA A +P TSW V ++TP + LNA+ RS+R+KII Sbjct: 249 ITESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDRLNADTRSVRDKIIA 308 Query: 62 IGVLCFILALVLSFIIARSISLPLKQLVGVMKATRTGNYLIRMDYEGKDEITELSQRFND 121 IG++CF ++L+LS +I+RSIS+PL++LV MK +G+ +R++ G DEI LS++FN+ Sbjct: 309 IGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGDTTVRVEQHGNDEIAVLSRKFNE 368 Query: 122 MASKVHQHNERLEELVAERTRELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAV 181 MA K+ Q+ E LEE V RTRELE+ANR+LEALSATD LTG+ANRRRFDEAL+ E+RRAV Sbjct: 369 MAGKLQQNREVLEEQVRLRTRELERANRKLEALSATDGLTGVANRRRFDEALANEMRRAV 428 Query: 182 RSQKPLALMMLDVDYFKNYNDRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 RS + LAL+MLDVDYFK YNDRYGHLAGD+CLR +ARV++ SSRRATDL AR Sbjct: 429 RSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVAR 480 >Q3M5I8.1 Q3M5I8_ANAVT Putative diguanylate cyclase (GGDEF domain) Length = 591 Score = 155 bits (392), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 86/212 (40%), Positives = 121/212 (57%) Query: 22 NREQLAAFAPVPRTSWMVVNVTPLNALNAEVRSIRNKIILIGVLCFILALVLSFIIARSI 81 N+ L A A + W V+ PL A V + + + VL + +++F I + + Sbjct: 291 NQVNLIAIASLKYKPWSVLFAQPLVVALAPVEKQIHDAMFLFVLIASVVTIIAFAIGQLL 350 Query: 82 SLPLKQLVGVMKATRTGNYLIRMDYEGKDEITELSQRFNDMASKVHQHNERLEELVAERT 141 + P+ L ++ TGN IR DEI +L++ FN+MA ++ E LE+ V ERT Sbjct: 351 TRPIIYLTNIVFQFTTGNLNIRAKISSTDEIGQLAKSFNNMAFQLQTSFETLEQRVQERT 410 Query: 142 RELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVRSQKPLALMMLDVDYFKNYN 201 EL AN++LE L D LT +ANRR FDE L E +R R Q+PL+L++ DVD FK+YN Sbjct: 411 AELVIANQKLEQLVNLDGLTQVANRRCFDERLKAEWKRLAREQQPLSLILFDVDKFKSYN 470 Query: 202 DRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 D YGHL GDDCL TIA+ ++ R DL AR Sbjct: 471 DYYGHLGGDDCLITIAQAVQQKLHRPADLLAR 502 >B2J9X3.1 B2J9X3_NOSP7 Diguanylate cyclase Length = 597 Score = 145 bits (367), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 86/220 (39%), Positives = 122/220 (55%), Gaps = 9/220 (4%) Query: 22 NREQLAAFAPVPRTSWMVVNVTPLNALNAEV-RSIRNKIILIGVLCFILALVLSFIIARS 80 N+ L A A + W V+ PL A V + I + + L ++ ++ ++ +F I + Sbjct: 289 NQVNLIAIARLKYKPWSVLFAQPLTVALAPVEKQISDAMFLFAIIASVVTII-AFAIGQV 347 Query: 81 ISLPLKQLVGVMKATRTGNYLIRMDYEGKDEITELSQRFNDMASKVHQHNERLEELVAER 140 ++ P+ L ++ G+ IR KDEI +L++ FN+MA ++ E LE+ V ER Sbjct: 348 LTKPIIYLTNIVFQFTAGHLDIRAKISSKDEIGQLAKSFNNMALQLQTSLETLEQRVQER 407 Query: 141 TREL-------EQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVRSQKPLALMMLD 193 T EL E AN +LE L D LT +ANRR FD L E + R Q+PL+L++LD Sbjct: 408 TAELVIAKEKAEDANHKLEQLVNLDGLTQVANRRCFDGRLQEEWKCLAREQRPLSLILLD 467 Query: 194 VDYFKNYNDRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 VD FK YND YGHL GDDCL TIA+ M+ R DL AR Sbjct: 468 VDKFKLYNDYYGHLGGDDCLITIAQTMQQVVHRPADLVAR 507 >B5ZPN4.1 B5ZPN4_RHILW Diguanylate cyclase Length = 660 Score = 145 bits (365), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 82/220 (37%), Positives = 126/220 (57%), Gaps = 10/220 (4%) Query: 21 DNREQLAAFAPVPRTSWMVVNVTPLNALNAEVRSIRNKIILIGVLC-FILALVLSFIIAR 79 ++ ++ A +P T W++ P + + + + ++ +G+L F+ +L I+ + Sbjct: 345 ESTSEITAVGRIPDTPWVLAVHYPKSLMRPAILTNLGIVVAVGLLTLFVELFILRSILQK 404 Query: 80 SISLPL------KQLVGVMKATRTGNYLIRMDYEGKDEITELSQRFNDMASKVHQHNERL 133 ++ PL QLVG T + L DEI EL++ F MA++VH +E L Sbjct: 405 QVAEPLVRLIHATQLVGRSGVTVANDAL---PTHSDDEIGELARDFASMAARVHTAHEAL 461 Query: 134 EELVAERTRELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVRSQKPLALMMLD 193 E + +RT ELE+ N++L +S TD +TG+ANRRRFDE L+ EL + Q L L M+D Sbjct: 462 EGKIRDRTSELERLNQKLLTISQTDEMTGVANRRRFDEVLASELAGLGQGQDLLMLAMVD 521 Query: 194 VDYFKNYNDRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 D+FK YNDRYGH AGD CL+ IARV+ ++R D+ AR Sbjct: 522 ADWFKGYNDRYGHPAGDACLKEIARVLERNTRSKQDVVAR 561 >A8FZK2.1 A8FZK2_SHESH Conserved hypothetical signaling protein Length = 480 Score = 137 bits (346), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 80/212 (37%), Positives = 119/212 (56%), Gaps = 14/212 (6%) Query: 24 EQLAAFAPVPRTSWMVVNVTPLNALNAEVRSIRNKIILIGVLCFILA-LVLSFIIARSIS 82 E+LAA + T W V VR + +++ VL IL L+++F+ +S Sbjct: 195 EELAAITSIESTGWFVATRQKTTEAYLPVRQLTESMLMYLVLSAILGVLIITFVFITMLS 254 Query: 83 LPLKQLVGVMKATRTGNY-LIRMDYEGKDEITELSQRFNDMASKVHQHNERLEELVAERT 141 PLK+ +K GN L ++ KDE+ +L FN + + RT Sbjct: 255 -PLKKAALSVKDMAQGNTPLKKLTIVHKDEVGDLIDGFNSLVDAIDG-----------RT 302 Query: 142 RELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVRSQKPLALMMLDVDYFKNYN 201 LE AN++L ALS TD LTG+ NRR F+E L E RA R+++PLAL M+D+D+FK YN Sbjct: 303 DALETANQKLAALSLTDELTGLGNRRHFNEKLEQEWIRASRTKQPLALGMIDIDFFKKYN 362 Query: 202 DRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 D+YGH+ GD+CL+ I++++ + RA DL+AR Sbjct: 363 DKYGHVLGDECLQEISKLLASIISRAGDLSAR 394