BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0018.p (293 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4GA36.1 A4GA36_HERAR Putative methylisocitrate lyase (2-methyli... 543 e-152 A6T3T0.1 A6T3T0_JANMA Carboxyvinyl-carboxyphosphonate phosphoryl... 535 e-150 E6UZL9.1 E6UZL9_VARPD Isocitrate lyase and phosphorylmutase 449 e-124 E8TXI9.1 E8TXI9_ALIDB Isocitrate lyase and phosphorylmutase 447 e-124 D0J326.1 D0J326_COMT2 Carboxyvinyl-carboxyphosphonate 443 e-122 >A4GA36.1 A4GA36_HERAR Putative methylisocitrate lyase (2-methylisocitrate lyase) (PrpB) EC=4.1.3.30 Length = 293 Score = 543 bits (1398), Expect = e-152, Method: Compositional matrix adjust. Identities = 265/283 (93%), Positives = 277/283 (97%) Query: 11 ILRDKVNARKGLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGMPDQGFIGLNELA 70 +LRDKV AR+GLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFG+PDQGFIGLNELA Sbjct: 11 VLRDKVYARRGLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGLPDQGFIGLNELA 70 Query: 71 DHTARIRDAVEIPLIVDADTGFGNALNVRHTIRTLERAGADAVQLEDQVSPKRCGHFSGK 130 DHTARIRDAV+IP+IVDADTGFGNALNVRHTIRTLERAGADAVQLEDQV+PKRCGHF+GK Sbjct: 71 DHTARIRDAVDIPIIVDADTGFGNALNVRHTIRTLERAGADAVQLEDQVAPKRCGHFNGK 130 Query: 131 EVISCAEMVGKIHAAVDARSNDGMLIMARTDACSVHGFEDALERAARYSEAGADILFVEA 190 EVISCAEMVGKIHAAVDARSN+GMLIMARTDA SVHGF+DALERAARYSEAGADILFVEA Sbjct: 131 EVISCAEMVGKIHAAVDARSNEGMLIMARTDARSVHGFDDALERAARYSEAGADILFVEA 190 Query: 191 IETADEIRRLPQALDKPQLVNLVIGGKTPIFNADELGGLGYGIVLYANAALQGAVAGMQK 250 ETADEIRRLPQALDKPQLVNLVIGGKTPIF+ADEL GLGYGIVLYANAALQGAVAGMQK Sbjct: 191 TETADEIRRLPQALDKPQLVNLVIGGKTPIFSADELSGLGYGIVLYANAALQGAVAGMQK 250 Query: 251 ALTVLRDNHRLDEDPNFVTPFAERQRLVNKPMFDLLEKKYAEK 293 ALTVLRD HRLDEDPNFVTPFAERQRLVNKP+FD LEKKYA+K Sbjct: 251 ALTVLRDTHRLDEDPNFVTPFAERQRLVNKPLFDQLEKKYADK 293 >A6T3T0.1 A6T3T0_JANMA Carboxyvinyl-carboxyphosphonate phosphorylmutase EC=2.7.8.23 Length = 293 Score = 535 bits (1379), Expect = e-150, Method: Compositional matrix adjust. Identities = 261/283 (92%), Positives = 274/283 (96%) Query: 11 ILRDKVNARKGLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGMPDQGFIGLNELA 70 +LRDKV AR+GLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGMPDQGFIGLNELA Sbjct: 11 VLRDKVYARRGLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGMPDQGFIGLNELA 70 Query: 71 DHTARIRDAVEIPLIVDADTGFGNALNVRHTIRTLERAGADAVQLEDQVSPKRCGHFSGK 130 DHTARIRDAV+IP+IVDADTGFGNALNVRHTIRTLERAGADAVQLEDQ+SPKRCGHF+GK Sbjct: 71 DHTARIRDAVDIPIIVDADTGFGNALNVRHTIRTLERAGADAVQLEDQISPKRCGHFNGK 130 Query: 131 EVISCAEMVGKIHAAVDARSNDGMLIMARTDACSVHGFEDALERAARYSEAGADILFVEA 190 EVISCAEMVGKIHAAVDARS+ GMLIMARTDA SVHGFEDALERAARYSEAGADILFVEA Sbjct: 131 EVISCAEMVGKIHAAVDARSDAGMLIMARTDARSVHGFEDALERAARYSEAGADILFVEA 190 Query: 191 IETADEIRRLPQALDKPQLVNLVIGGKTPIFNADELGGLGYGIVLYANAALQGAVAGMQK 250 ETADEIRRLPQALDKPQLVNLVIGGKTPIF+A+EL GLGYGIVLYANAALQGAVAGMQK Sbjct: 191 TETADEIRRLPQALDKPQLVNLVIGGKTPIFSANELAGLGYGIVLYANAALQGAVAGMQK 250 Query: 251 ALTVLRDNHRLDEDPNFVTPFAERQRLVNKPMFDLLEKKYAEK 293 ALTVLRD HRLDEDP+ V+PF+ERQRLVNKP FD LEKKYA+K Sbjct: 251 ALTVLRDTHRLDEDPSLVSPFSERQRLVNKPFFDQLEKKYADK 293 >E6UZL9.1 E6UZL9_VARPD Isocitrate lyase and phosphorylmutase Length = 293 Score = 449 bits (1154), Expect = e-124, Method: Compositional matrix adjust. Identities = 216/289 (74%), Positives = 249/289 (86%), Gaps = 1/289 (0%) Query: 2 TNLSQTTKQILRDKVNARKGLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGMPDQ 61 ++L T KQ L+ AR+GL+VPGAFNALSA+V+ DLGF+A+YITGAGVTNM+FGMPDQ Sbjct: 5 SSLMSTRKQ-LKSLAEARRGLIVPGAFNALSAKVVEDLGFKAIYITGAGVTNMWFGMPDQ 63 Query: 62 GFIGLNELADHTARIRDAVEIPLIVDADTGFGNALNVRHTIRTLERAGADAVQLEDQVSP 121 GF+GL E+ADHTARIRDAV +PLIVDADTGFGNALNVRHT+RTLERAGAD +Q EDQV+P Sbjct: 64 GFMGLAEIADHTARIRDAVSVPLIVDADTGFGNALNVRHTVRTLERAGADCIQFEDQVAP 123 Query: 122 KRCGHFSGKEVISCAEMVGKIHAAVDARSNDGMLIMARTDACSVHGFEDALERAARYSEA 181 KRCGHFSGKEVIS E V KI AAVDAR + +LIMARTDA +VHGFE A+ERA +++EA Sbjct: 124 KRCGHFSGKEVISTEEAVSKIKAAVDARQDQELLIMARTDAAAVHGFEAAVERAQKFAEA 183 Query: 182 GADILFVEAIETADEIRRLPQALDKPQLVNLVIGGKTPIFNADELGGLGYGIVLYANAAL 241 GADILFVEA+ TADEIR LPQ L KPQL+N+VIGGKTPIFNA++LG LGYGIVLYANAAL Sbjct: 184 GADILFVEAVTTADEIRALPQRLAKPQLMNMVIGGKTPIFNAEDLGELGYGIVLYANAAL 243 Query: 242 QGAVAGMQKALTVLRDNHRLDEDPNFVTPFAERQRLVNKPMFDLLEKKY 290 QGAV+GMQKALTVLRD ++ E VT FAERQRLV KP +D LEK+Y Sbjct: 244 QGAVSGMQKALTVLRDEKQVLESSGLVTTFAERQRLVGKPEWDALEKRY 292 >E8TXI9.1 E8TXI9_ALIDB Isocitrate lyase and phosphorylmutase Length = 286 Score = 447 bits (1151), Expect = e-124, Method: Compositional matrix adjust. Identities = 214/283 (75%), Positives = 246/283 (86%) Query: 8 TKQILRDKVNARKGLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGMPDQGFIGLN 67 TKQ L+ V AR GL+VPGAFNALSARVIADLGF+A+Y+TGAGVTNM+FGMPDQGF+GL+ Sbjct: 3 TKQRLKQLVEARNGLIVPGAFNALSARVIADLGFQAIYVTGAGVTNMWFGMPDQGFMGLH 62 Query: 68 ELADHTARIRDAVEIPLIVDADTGFGNALNVRHTIRTLERAGADAVQLEDQVSPKRCGHF 127 E+A+HTARIRDAV++PLIVDADTGFGNALNV HT+RTLERAGAD +QLEDQV+PKRCGHF Sbjct: 63 EIAEHTARIRDAVDVPLIVDADTGFGNALNVVHTVRTLERAGADCIQLEDQVTPKRCGHF 122 Query: 128 SGKEVISCAEMVGKIHAAVDARSNDGMLIMARTDACSVHGFEDALERAARYSEAGADILF 187 +GKEVIS E VGKI AA DAR + G LIMARTDA + HGFE A+ERA +++EAGADILF Sbjct: 123 AGKEVISAEEAVGKIKAAADARRDPGFLIMARTDAAATHGFEAAVERAQKFAEAGADILF 182 Query: 188 VEAIETADEIRRLPQALDKPQLVNLVIGGKTPIFNADELGGLGYGIVLYANAALQGAVAG 247 VEA+ A+E+R LPQ L KPQL+N+VIGGKTPIFNA++LG LGYGIVLYANAALQGAVAG Sbjct: 183 VEAVTRAEEVRALPQRLAKPQLMNMVIGGKTPIFNAEQLGELGYGIVLYANAALQGAVAG 242 Query: 248 MQKALTVLRDNHRLDEDPNFVTPFAERQRLVNKPMFDLLEKKY 290 MQKALTVLRD + E VTPFAERQ LV KP +D LEK+Y Sbjct: 243 MQKALTVLRDEKEVQESSGLVTPFAERQLLVGKPAWDALEKRY 285 >D0J326.1 D0J326_COMT2 Carboxyvinyl-carboxyphosphonate Length = 286 Score = 443 bits (1139), Expect = e-122, Method: Compositional matrix adjust. Identities = 209/282 (74%), Positives = 245/282 (86%) Query: 9 KQILRDKVNARKGLLVPGAFNALSARVIADLGFEALYITGAGVTNMYFGMPDQGFIGLNE 68 KQ L+ +AR+G++VPGAFNA+SAR+IADLGFEA+Y+TGAGVTNM+FGMPDQGF+GL + Sbjct: 4 KQQLKALADARRGVIVPGAFNAMSARLIADLGFEAIYVTGAGVTNMWFGMPDQGFMGLGD 63 Query: 69 LADHTARIRDAVEIPLIVDADTGFGNALNVRHTIRTLERAGADAVQLEDQVSPKRCGHFS 128 +ADHTARIRDAVE+PL+VDADTGFGNA+N H +RTLERAGAD +QLEDQVSPKRCGHF+ Sbjct: 64 IADHTARIRDAVEVPLLVDADTGFGNAVNTYHAVRTLERAGADCIQLEDQVSPKRCGHFN 123 Query: 129 GKEVISCAEMVGKIHAAVDARSNDGMLIMARTDACSVHGFEDALERAARYSEAGADILFV 188 GK VI EM+GKI AAVDAR + G LIMARTDA +VHGFE A+ERA ++ EAGADILFV Sbjct: 124 GKAVIETGEMLGKIKAAVDARRDSGTLIMARTDAAAVHGFEAAIERAQQFQEAGADILFV 183 Query: 189 EAIETADEIRRLPQALDKPQLVNLVIGGKTPIFNADELGGLGYGIVLYANAALQGAVAGM 248 EA+ A+E+R LPQ L PQL+N+VIGGKTPIFNADELG LGYG VLYANAALQGAVAGM Sbjct: 184 EAVTQAEEVRALPQRLQAPQLMNMVIGGKTPIFNADELGELGYGFVLYANAALQGAVAGM 243 Query: 249 QKALTVLRDNHRLDEDPNFVTPFAERQRLVNKPMFDLLEKKY 290 QK LT+LRD+H++DEDP V PF ERQRLVNK +D LE+KY Sbjct: 244 QKCLTLLRDDHKVDEDPAIVAPFLERQRLVNKDFWDGLEQKY 285