BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0012.p (581 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0P5.1 D8J0P5_HERSS Propionyl-CoA ligase protein EC=6.2.1.17 976 0.0 A4GA39.1 A4GA39_HERAR Propionate--CoA ligase (Propionyl-CoA synt... 912 0.0 A6T3T3.1 A6T3T3_JANMA Propionyl-CoA synthetase EC=6.2.1.17 902 0.0 D2TK49.1 D2TK49_CITRI Propionate--coA ligase EC=6.2.1.17 861 0.0 B5R5W2.1 B5R5W2_SALG2 PrpE protein 860 0.0 >D8J0P5.1 D8J0P5_HERSS Propionyl-CoA ligase protein EC=6.2.1.17 Length = 628 Score = 976 bits (2522), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/578 (79%), Positives = 511/578 (88%), Gaps = 4/578 (0%) Query: 1 MSYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDR 60 M Y FY+QS++ P+ FWA EA+RI W PF++T DY+RPPFARWFI G+TNLCHNAVDR Sbjct: 1 MQYEQFYRQSVEQPEAFWAQEAQRIHWQQPFSRTLDYSRPPFARWFIDGQTNLCHNAVDR 60 Query: 61 HLAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAE 120 HL +RA QAALIA+STETN+E+ YT+ EL +EV AMAA M +LGV+RGDRVLIYMPMIAE Sbjct: 61 HLPERAQQAALIAISTETNSERVYTYAELQQEVMAMAASMQALGVQRGDRVLIYMPMIAE 120 Query: 121 AVFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDE 180 AVFAMLACARIGAVHSVVFGGFAS SLA+RIDDAQP LIVSADAGSRGG+V+ YKGLLDE Sbjct: 121 AVFAMLACARIGAVHSVVFGGFASNSLASRIDDAQPRLIVSADAGSRGGKVIPYKGLLDE 180 Query: 181 AIRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYT 240 AI +AQH+P HVLL DRGLA M RT RDVDY LR Q+L VPV WLESN SYILYT Sbjct: 181 AIAMAQHRPQHVLLVDRGLAPMARTAQRDVDYAPLRTQHLGQQVPVTWLESNASSYILYT 240 Query: 241 SGTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAG 300 SGTTGKPKGVQRDVGGYAVALA+SM +IFCG PGETYFCTSDIGWVVGHSYIVYGPL+AG Sbjct: 241 SGTTGKPKGVQRDVGGYAVALASSMQHIFCGQPGETYFCTSDIGWVVGHSYIVYGPLIAG 300 Query: 301 MATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSL 360 MAT+LYEGLP+ +PD GIWWS+VEKYKVTRMFS+PTAIRVLKKQP ECM RYD SSL Sbjct: 301 MATVLYEGLPI----RPDAGIWWSIVEKYKVTRMFSAPTAIRVLKKQPPECMERYDTSSL 356 Query: 361 KSLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPL 420 K+LYLAGEPLDETTS+WISGAL VPVIDNYWQTESGWPI+SIAKG+DDKPTRLGSPGVP+ Sbjct: 357 KALYLAGEPLDETTSSWISGALKVPVIDNYWQTESGWPIISIAKGIDDKPTRLGSPGVPM 416 Query: 421 YGYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYST 480 GY++ I++E+TGE CG ++KGVV IEGPLPPGCMQTVY DDERFVNTYW + +VYST Sbjct: 417 PGYRLAILDEATGEPCGPDQKGVVAIEGPLPPGCMQTVYGDDERFVNTYWRSLPREVYST 476 Query: 481 FDWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQV 540 FDWGIRD+DGYYFILGRTDDVINVAGHRLGTREIEESISSH NVSEVAVVGV+DKLKGQV Sbjct: 477 FDWGIRDKDGYYFILGRTDDVINVAGHRLGTREIEESISSHPNVSEVAVVGVEDKLKGQV 536 Query: 541 AIAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 A AF IPKQA +AT E R+ALEAEIM VVDKQIGAVG Sbjct: 537 AFAFAIPKQAYTIATPEQRKALEAEIMAVVDKQIGAVG 574 >A4GA39.1 A4GA39_HERAR Propionate--CoA ligase (Propionyl-CoA synthetase) EC=6.2.1.17 Length = 634 Score = 912 bits (2357), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/577 (73%), Positives = 494/577 (85%), Gaps = 4/577 (0%) Query: 2 SYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDRH 61 +Y +FY++SIDDP TFWA +A+RI+W+ PFT+T DY PPF +WF+GGET+LC+NAVDRH Sbjct: 7 AYDAFYRRSIDDPHTFWAEQAQRIEWNKPFTRTLDYDHPPFTKWFVGGETSLCYNAVDRH 66 Query: 62 LAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAEA 121 LA RADQ ALIA+STET++EK YTF +LH EV+ AA+M SLGV +GDRVLIYMPM+AEA Sbjct: 67 LATRADQPALIAISTETDSEKVYTFAQLHAEVNRCAAMMQSLGVSQGDRVLIYMPMVAEA 126 Query: 122 VFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDEA 181 FAMLACARIGA+HSVVFGGFAS SLATRIDDA P LI+SADAGSRG V+ YK LLDEA Sbjct: 127 AFAMLACARIGAIHSVVFGGFASNSLATRIDDATPVLILSADAGSRGCHVMPYKSLLDEA 186 Query: 182 IRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYTS 241 I LA+HKP HVL+ +RGLA M GRD+DY +LR +++DA VPV WLESN PSYILYTS Sbjct: 187 IVLAEHKPTHVLMVNRGLAPMQTVAGRDIDYATLREKHMDAAVPVVWLESNAPSYILYTS 246 Query: 242 GTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAGM 301 GTTGKPKGV RDVGGYAVAL SM IFCG GET+FCTSDIGWVVGHSYI+YGPL+AGM Sbjct: 247 GTTGKPKGVVRDVGGYAVALTTSMDLIFCGKAGETFFCTSDIGWVVGHSYIIYGPLLAGM 306 Query: 302 ATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSLK 361 AT+LYEGLP+ +PD IWWS+VEKYKVTRM S+PTAIRVLKKQP E + ++DLSSLK Sbjct: 307 ATVLYEGLPI----RPDASIWWSIVEKYKVTRMSSAPTAIRVLKKQPLELLKKHDLSSLK 362 Query: 362 SLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPLY 421 +LYLAGEPLD+TTS WISG L VPVIDNYWQTE+GWPI+SIAKGV DKPTR GSPG+PLY Sbjct: 363 ALYLAGEPLDQTTSEWISGVLNVPVIDNYWQTETGWPIISIAKGVGDKPTRSGSPGLPLY 422 Query: 422 GYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYSTF 481 GYK I+NE +GE C NEKGVV+IEGPLPPGC+QT+Y DD+RFV+TYW NF+ + YSTF Sbjct: 423 GYKTKIINEISGEECAANEKGVVIIEGPLPPGCLQTLYGDDQRFVSTYWRNFKREAYSTF 482 Query: 482 DWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQVA 541 DWGIRD DGYYFILGRTDDVINVAGHRLGTREIEESISSH NVSEVAVVGV++ +KGQ A Sbjct: 483 DWGIRDADGYYFILGRTDDVINVAGHRLGTREIEESISSHGNVSEVAVVGVENPIKGQCA 542 Query: 542 IAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 +AFVI K A A+ E + LEAEIM+VVDK++G++G Sbjct: 543 VAFVILKNAALAASPEEAKKLEAEIMKVVDKRLGSIG 579 >A6T3T3.1 A6T3T3_JANMA Propionyl-CoA synthetase EC=6.2.1.17 Length = 634 Score = 902 bits (2330), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/577 (75%), Positives = 499/577 (86%), Gaps = 4/577 (0%) Query: 2 SYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDRH 61 +Y +FY+ S+DDP +FWA +A+RIDWH PF+KT DY +PPFA+WF+GGETNLC+NAVDRH Sbjct: 7 AYDAFYRLSVDDPHSFWATQAKRIDWHKPFSKTLDYDKPPFAKWFVGGETNLCYNAVDRH 66 Query: 62 LAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAEA 121 LA RADQ AL+A+STET+TE TYT+ +LH EVS AA+M +LGV +GDRVLIYMPM+AEA Sbjct: 67 LATRADQPALVAISTETDTETTYTYAQLHAEVSRSAAMMQALGVGQGDRVLIYMPMVAEA 126 Query: 122 VFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDEA 181 FAMLACARIGA+HSVVFGGFASTSLATRIDDA P LI+SADAGSRG V YK LLDEA Sbjct: 127 AFAMLACARIGAIHSVVFGGFASTSLATRIDDATPVLIISADAGSRGCHVTPYKCLLDEA 186 Query: 182 IRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYTS 241 I LA+HKPAHVL+ DRGLA M GRDVDY +LR Q++DA VPVAWLESN PSYILYTS Sbjct: 187 IALAEHKPAHVLMLDRGLAPMKTIEGRDVDYATLRRQHMDAVVPVAWLESNAPSYILYTS 246 Query: 242 GTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAGM 301 GTTGKPKGV RDVGGYAVALA SM IFCG PGET+FCTSDIGWVVGHSYI+YGPL+AGM Sbjct: 247 GTTGKPKGVLRDVGGYAVALATSMDLIFCGKPGETFFCTSDIGWVVGHSYIIYGPLLAGM 306 Query: 302 ATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSLK 361 TILYEGLP+ +PD IWWS+VEKYKVTRM S+PTAIRVLKKQP E + ++DLSSLK Sbjct: 307 TTILYEGLPI----RPDASIWWSIVEKYKVTRMSSAPTAIRVLKKQPLELLQKHDLSSLK 362 Query: 362 SLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPLY 421 +LYLAGEPLD+TTS+WISG LGVPVIDNYWQTE+GWPI+S+AKGV DKPTR GSPG P+Y Sbjct: 363 ALYLAGEPLDQTTSDWISGVLGVPVIDNYWQTETGWPIISVAKGVGDKPTRSGSPGQPMY 422 Query: 422 GYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYSTF 481 GYK ++NE TGE C NEKGVV+IEGPLPPGC+QT+Y DD+RFV+TYW NF+ + YSTF Sbjct: 423 GYKAKVINEETGEECAPNEKGVVIIEGPLPPGCLQTLYGDDQRFVSTYWRNFKREAYSTF 482 Query: 482 DWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQVA 541 DWGIRD DGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGV++ +KGQ A Sbjct: 483 DWGIRDADGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVENPIKGQCA 542 Query: 542 IAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 +AFVI K A A A + + LEAEIM+VVDK++G +G Sbjct: 543 VAFVILKNAAAAADPDEARKLEAEIMKVVDKRLGPIG 579 >D2TK49.1 D2TK49_CITRI Propionate--coA ligase EC=6.2.1.17 Length = 628 Score = 861 bits (2225), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/578 (70%), Positives = 477/578 (82%), Gaps = 4/578 (0%) Query: 1 MSYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDR 60 MS++ FYQ+SI P+ FWA +ARRIDW PFT+T D++RPPFARWF GG TNLCHNAVDR Sbjct: 1 MSFSEFYQRSITQPEAFWAEQARRIDWQKPFTRTLDHSRPPFARWFCGGTTNLCHNAVDR 60 Query: 61 HLAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAE 120 LA + + ALIAVS+ET E+T+TFR+LH EV+ +A+++LSLGV+RGDRVL+YMPMIAE Sbjct: 61 WLATQPEALALIAVSSETEEERTFTFRQLHDEVNVVASMLLSLGVRRGDRVLVYMPMIAE 120 Query: 121 AVFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDE 180 A +LACARIGA+HSVVFGGFAS S+A RIDDA+P LIVSADAG RGG+V+ YK LLD+ Sbjct: 121 AHITLLACARIGAIHSVVFGGFASHSVAARIDDARPVLIVSADAGVRGGKVLPYKKLLDD 180 Query: 181 AIRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYT 240 AI AQH+P HVLL DRGLA+M R GRD+D+ SLR Q+ A PVAWLESNE S ILYT Sbjct: 181 AIAQAQHQPKHVLLVDRGLAKMARIAGRDLDFASLRQQHCGARTPVAWLESNETSCILYT 240 Query: 241 SGTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAG 300 SGTTGKPKGVQRDVGGYAVALA SM IF G G +FC SDIGWVVGHSYIVY PL+AG Sbjct: 241 SGTTGKPKGVQRDVGGYAVALATSMDTIFGGRAGGVFFCASDIGWVVGHSYIVYAPLLAG 300 Query: 301 MATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSL 360 MATI+YEGLP PD G+WW +VEKY+V RMFS+PTAIRVLKK P + +DLSSL Sbjct: 301 MATIVYEGLPTY----PDCGVWWKIVEKYRVNRMFSAPTAIRVLKKFPTAQIRNHDLSSL 356 Query: 361 KSLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPL 420 + LYLAGEPLDE T+ W++ LGVPVIDNYWQTESGWPI+++A+ +DD+P+RLGSPGVP+ Sbjct: 357 EVLYLAGEPLDEPTAAWVTQTLGVPVIDNYWQTESGWPIMALARQLDDRPSRLGSPGVPM 416 Query: 421 YGYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYST 480 YGY + ++NE TGE CGVNEKG+VVIEGPLPPGC+QT++ DDERFV TYWS F QVY+T Sbjct: 417 YGYNVQLLNEVTGEPCGVNEKGMVVIEGPLPPGCIQTIWGDDERFVKTYWSLFSRQVYAT 476 Query: 481 FDWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQV 540 FDWGIRD DGYYFILGRTDDVINVAGHRLGTREIEESIS + NV+EVAVVGV D LKGQV Sbjct: 477 FDWGIRDADGYYFILGRTDDVINVAGHRLGTREIEESISGYPNVAEVAVVGVKDALKGQV 536 Query: 541 AIAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 A+AFVIPKQ+D++ E + E IM +VD QIG G Sbjct: 537 AVAFVIPKQSDSLEDREAAHSEEEAIMALVDSQIGHFG 574 >B5R5W2.1 B5R5W2_SALG2 PrpE protein Length = 628 Score = 860 bits (2221), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/578 (69%), Positives = 484/578 (83%), Gaps = 4/578 (0%) Query: 1 MSYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDR 60 MS++ FYQ+SI++P+ FWA +ARRIDW PFT+T D++RPPFARWF GG TNLCHNAVDR Sbjct: 1 MSFSEFYQRSINEPEAFWAEQARRIDWRQPFTQTLDHSRPPFARWFCGGTTNLCHNAVDR 60 Query: 61 HLAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAE 120 L ++ + ALIAVS+ET+ E+T+TF +LH EV+A+AA++LSLGV+RGDRVL+YMPMIAE Sbjct: 61 WLDKQPEALALIAVSSETDEERTFTFSQLHDEVNAVAAMLLSLGVQRGDRVLVYMPMIAE 120 Query: 121 AVFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDE 180 A +LACARIGA+HSVVFGGFAS S+A RIDDA+P LIVSADAG+RGG+++ YK LLD+ Sbjct: 121 AQITLLACARIGAIHSVVFGGFASHSVAARIDDARPALIVSADAGARGGKILPYKKLLDD 180 Query: 181 AIRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYT 240 AI AQH+P HVLL DRGLA+M GRD+D+ +LR Q+L A VPVAWLESNE S ILYT Sbjct: 181 AIAQAQHQPKHVLLVDRGLAKMAWVDGRDLDFATLRQQHLGASVPVAWLESNETSCILYT 240 Query: 241 SGTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAG 300 SGTTGKPKGVQRDVGGYAVALA SM IF G G +FC SDIGWVVGHSYIVY PL+AG Sbjct: 241 SGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGVFFCASDIGWVVGHSYIVYAPLLAG 300 Query: 301 MATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSL 360 MATI+YEGLP PD G+WW +VEKY+V RMFS+PTAIRVLKK P + +DLSSL Sbjct: 301 MATIVYEGLPTY----PDCGVWWKIVEKYQVNRMFSAPTAIRVLKKFPTAQIRNHDLSSL 356 Query: 361 KSLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPL 420 ++LYLAGEPLDE T++W++ LGVPVIDNYWQTESGWPI+++A+ +DD+P+RLGSPGVP+ Sbjct: 357 EALYLAGEPLDEPTASWVTETLGVPVIDNYWQTESGWPIMALARALDDRPSRLGSPGVPM 416 Query: 421 YGYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYST 480 YGY + ++NE TGE CG+NEKG++VIEGPLPPGC+QT++ DD RFV TYWS F QVY+T Sbjct: 417 YGYNVQLLNEVTGEPCGINEKGMLVIEGPLPPGCIQTIWGDDARFVKTYWSLFTRQVYAT 476 Query: 481 FDWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQV 540 FDWGIRD +GYYFILGRTDDVIN+AGHRLGTREIEESISS+ NV+EVAVVG+ D LKGQV Sbjct: 477 FDWGIRDAEGYYFILGRTDDVINIAGHRLGTREIEESISSYPNVAEVAVVGIKDALKGQV 536 Query: 541 AIAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 A+AFVIPKQ+D +A E + E IM +VD QIG G Sbjct: 537 AVAFVIPKQSDTLADREAARDEENAIMALVDNQIGHFG 574