BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0048.p (372 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IQP6.1 D8IQP6_HERSS D-alanyl-D-alanine-endopeptidase (Penicill... 545 e-153 A4G3C0.2 A4G3C0_HERAR D-alanyl-D-alanine endopeptidase (DD-endop... 466 e-129 A6SVX4.1 A6SVX4_JANMA D-alanyl-D-alanine-endopeptidase EC=3.4.99.- 464 e-128 F1W1W5.1 F1W1W5_9BURK Penicillin-binding protein (D-alanyl-D-ala... 399 e-109 B0LFS7.1 B0LFS7_9BACT Endopeptidase 391 e-106 >D8IQP6.1 D8IQP6_HERSS D-alanyl-D-alanine-endopeptidase (Penicillin-binding) protein EC=3.4.-.- Length = 366 Score = 545 bits (1403), Expect = e-153, Method: Compositional matrix adjust. Identities = 292/372 (78%), Positives = 323/372 (86%), Gaps = 6/372 (1%) Query: 1 MLKSALAAVATALLVLVGTSSVQAQTSPNSKKTAVKKAVIKKNVVHRRPVAAPKRATQAS 60 M+KSALA + + L + G + AQT N+ K VKKAV K+ +PV+ + + S Sbjct: 1 MIKSALAVLTSLLFIHAGLAPAAAQTVNNTAKKPVKKAVAKRAA---QPVS--RTVAKGS 55 Query: 61 LDRREKLVKKVAVVHGKRRVVYQRVAAMPTVPVVPPVMTAGDMAGLNLTQDPLALRSNVA 120 L+ REKLV+KV VV GKR+V YQRV+A P+VPVVPPVMTAGDMAGLNLT DPLALRSNVA Sbjct: 56 LNNREKLVRKVTVVKGKRQVSYQRVSAAPSVPVVPPVMTAGDMAGLNLTPDPLALRSNVA 115 Query: 121 LVIDQASSQVLFEKNSSVALPIASVTKLMTSLVVVEARQNMEEILTVSDDDVDRQKHSSS 180 LVIDQA+SQVLFEKNS VALPIASVTKLMT+LVVVEARQNMEE+LTV+DDDVDR+KHSSS Sbjct: 116 LVIDQANSQVLFEKNSGVALPIASVTKLMTALVVVEARQNMEEVLTVTDDDVDREKHSSS 175 Query: 181 RLRVGAQLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSLGMMDTHYVD 240 RLRVGA LSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSLGMMDT YVD Sbjct: 176 RLRVGATLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSLGMMDTRYVD 235 Query: 241 STGLSSNNVASARDLAKLVVAAYNYPIIRQYSTDAKYMVEPSGHALQYASSNRLVASKDW 300 STGLSS NVASARDLAKLVVAAYNYPIIRQYSTD KYMVEPSGHALQY SSNRL ++K+W Sbjct: 236 STGLSSQNVASARDLAKLVVAAYNYPIIRQYSTDPKYMVEPSGHALQYNSSNRLTSNKEW 295 Query: 301 DIGLQKTGYINEAGHCLVMLTKIEGRSVVMVFLDSKGKLSHVGDAARMRKWLSEQGPQNL 360 DIGLQKTG+INEAGHCLVM T+IEGR +VMVFLDSKG+LSHVGDAARMRKWL + P NL Sbjct: 296 DIGLQKTGFINEAGHCLVMYTRIEGRPIVMVFLDSKGRLSHVGDAARMRKWLVDDQPSNL 355 Query: 361 TRVNLRARADEG 372 TR+ + RADEG Sbjct: 356 TRMKM-VRADEG 366 >A4G3C0.2 A4G3C0_HERAR D-alanyl-D-alanine endopeptidase (DD-endopeptidase) (Penicillin-binding protein 5) (PBP-5) EC=3.4.16.4 Length = 308 Score = 466 bits (1200), Expect = e-129, Method: Compositional matrix adjust. Identities = 223/302 (73%), Positives = 265/302 (87%), Gaps = 1/302 (0%) Query: 65 EKLVKKVAVVHGKRRVVYQRVAAMPTVPVVPPVMTAGDMAGLNLTQDPLALRSNVALVID 124 EKLVKKV V+GK+RV+YQRVA P +P VPPVMTAGD+AGL++T+D LAL S+VALVID Sbjct: 5 EKLVKKVVTVNGKKRVIYQRVA-QPVIPTVPPVMTAGDIAGLSMTRDALALASSVALVID 63 Query: 125 QASSQVLFEKNSSVALPIASVTKLMTSLVVVEARQNMEEILTVSDDDVDRQKHSSSRLRV 184 Q++S+VLFEKN++V LPIAS+TKLMT LVVVEA+Q+M E+L V+ +D+DR+K+SSSRLRV Sbjct: 64 QSTSEVLFEKNANVTLPIASITKLMTGLVVVEAQQDMNEMLEVTAEDIDREKNSSSRLRV 123 Query: 185 GAQLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSLGMMDTHYVDSTGL 244 G+QLSR +MLHIALMSSENRAASALGR+YPGGL AFVA MNAKA+SLGM THYVDSTGL Sbjct: 124 GSQLSRANMLHIALMSSENRAASALGRHYPGGLRAFVATMNAKAKSLGMRGTHYVDSTGL 183 Query: 245 SSNNVASARDLAKLVVAAYNYPIIRQYSTDAKYMVEPSGHALQYASSNRLVASKDWDIGL 304 SSNNVASARDLAKLVV AYN+PI+RQYSTD+KY+VEP G ALQYA+SNRLV + DW+IG+ Sbjct: 184 SSNNVASARDLAKLVVEAYNHPILRQYSTDSKYVVEPGGRALQYANSNRLVTNPDWEIGI 243 Query: 305 QKTGYINEAGHCLVMLTKIEGRSVVMVFLDSKGKLSHVGDAARMRKWLSEQGPQNLTRVN 364 QKTGYI+EAG CLVM T I+ R +VM+FLDSKGK S +GDAAR+RKWL PQN+ R N Sbjct: 244 QKTGYISEAGRCLVMQTNIKERPIVMIFLDSKGKFSRLGDAARIRKWLETMEPQNVARSN 303 Query: 365 LR 366 R Sbjct: 304 RR 305 >A6SVX4.1 A6SVX4_JANMA D-alanyl-D-alanine-endopeptidase EC=3.4.99.- Length = 436 Score = 464 bits (1194), Expect = e-128, Method: Compositional matrix adjust. Identities = 223/304 (73%), Positives = 264/304 (86%), Gaps = 1/304 (0%) Query: 57 TQASLDRREKLVKKVAVVHGKRRVVYQRVAAMPTVPVVPPVMTAGDMAGLNLTQDPLALR 116 T SL+ EKLVKK VV GK++V+YQRVA P + VVPPV+TAGD+AGLN+T+D LAL Sbjct: 125 TTTSLNSNEKLVKKEVVVRGKKKVIYQRVAK-PVMTVVPPVLTAGDIAGLNMTRDSLALA 183 Query: 117 SNVALVIDQASSQVLFEKNSSVALPIASVTKLMTSLVVVEARQNMEEILTVSDDDVDRQK 176 SNVALV+DQ++S VLFEKN++V LPIAS+TKLMT LVVVEA+Q+M EIL V+++D+DR+K Sbjct: 184 SNVALVLDQSTSAVLFEKNANVTLPIASITKLMTGLVVVEAQQDMNEILEVTEEDIDREK 243 Query: 177 HSSSRLRVGAQLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSLGMMDT 236 +SSSRLRVG+QLSR +MLHIALMSSENRAASALGR+YPGG+ AFVAAMNAKARSLGM T Sbjct: 244 NSSSRLRVGSQLSRANMLHIALMSSENRAASALGRHYPGGIRAFVAAMNAKARSLGMNGT 303 Query: 237 HYVDSTGLSSNNVASARDLAKLVVAAYNYPIIRQYSTDAKYMVEPSGHALQYASSNRLVA 296 HYVDSTGLSSNNVASA DLAKLV+AA N+ I+RQYSTD KY+VEP G ALQYA+SNRLV Sbjct: 304 HYVDSTGLSSNNVASAADLAKLVIAASNHSILRQYSTDTKYVVEPGGRALQYANSNRLVN 363 Query: 297 SKDWDIGLQKTGYINEAGHCLVMLTKIEGRSVVMVFLDSKGKLSHVGDAARMRKWLSEQG 356 + DW+IG+QKTGYI+EAG CLVM I GR +VM+FLDSKGKLS +GDAAR+RKWL Q Sbjct: 364 NPDWEIGIQKTGYISEAGRCLVMQANINGRPIVMIFLDSKGKLSRLGDAARIRKWLETQH 423 Query: 357 PQNL 360 PQN+ Sbjct: 424 PQNI 427 >F1W1W5.1 F1W1W5_9BURK Penicillin-binding protein (D-alanyl-D-alanine-endopeptidase) (DD-endopeptidase) Length = 351 Score = 399 bits (1026), Expect = e-109, Method: Compositional matrix adjust. Identities = 191/261 (73%), Positives = 226/261 (86%) Query: 101 GDMAGLNLTQDPLALRSNVALVIDQASSQVLFEKNSSVALPIASVTKLMTSLVVVEARQN 160 GD+AGLNLT+D L L+SNVALV+DQ++S+VLFEKNS+VALPIAS+TKLMTS+VVVE+ QN Sbjct: 75 GDLAGLNLTRDALDLKSNVALVMDQSNSKVLFEKNSNVALPIASITKLMTSMVVVESNQN 134 Query: 161 MEEILTVSDDDVDRQKHSSSRLRVGAQLSRDDMLHIALMSSENRAASALGRNYPGGLPAF 220 M+E++ V+ DD+DR+K+SSSRLRVG+ LSR +MLHIALMSSENRAASALGRNYPGGLPAF Sbjct: 135 MDEMIEVTSDDIDREKNSSSRLRVGSILSRSNMLHIALMSSENRAASALGRNYPGGLPAF 194 Query: 221 VAAMNAKARSLGMMDTHYVDSTGLSSNNVASARDLAKLVVAAYNYPIIRQYSTDAKYMVE 280 V AMNAKA+SLGM DT YVDSTGLSS+NVASA+DLAKLV+AA + II QYSTD KY+V+ Sbjct: 195 VGAMNAKAKSLGMNDTRYVDSTGLSSHNVASAQDLAKLVIAARQHQIIGQYSTDTKYVVK 254 Query: 281 PSGHALQYASSNRLVASKDWDIGLQKTGYINEAGHCLVMLTKIEGRSVVMVFLDSKGKLS 340 P ALQY++SN LV + WDI LQKTGYINEAG C+VMLT IEGR +VMVFLDSKGK S Sbjct: 255 PGSGALQYSNSNHLVGNPAWDIDLQKTGYINEAGRCMVMLTNIEGRPIVMVFLDSKGKQS 314 Query: 341 HVGDAARMRKWLSEQGPQNLT 361 DA R+RKW+ P+NLT Sbjct: 315 RTADAGRIRKWIEALKPENLT 335 >B0LFS7.1 B0LFS7_9BACT Endopeptidase Length = 368 Score = 391 bits (1004), Expect = e-106, Method: Compositional matrix adjust. Identities = 198/314 (63%), Positives = 241/314 (76%), Gaps = 6/314 (1%) Query: 47 RRPVAAPKRATQASLDRREKLVKKVAVVHGKRRVVYQRVAAMPTVPVVPPVMTAGDMAGL 106 RR VAA +AS R ++++ VV+GKR+ VYQRV + PV P + GD AGL Sbjct: 46 RRDVAA-----RASSPPRANVIRRTIVVNGKRKTVYQRVM-LARAPVAAPRPSFGDRAGL 99 Query: 107 NLTQDPLALRSNVALVIDQASSQVLFEKNSSVALPIASVTKLMTSLVVVEARQNMEEILT 166 NLT+DPL L S+VALV+DQ S++VLFEKNS +ALPIAS+TKLMT LVVVEA Q+M EILT Sbjct: 100 NLTRDPLDLASSVALVLDQNSAEVLFEKNSKIALPIASITKLMTGLVVVEANQDMNEILT 159 Query: 167 VSDDDVDRQKHSSSRLRVGAQLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNA 226 V++DDVD +K +SSRLRVG+QLSR +LHIALMSSENRAA+ALGRNYPGG+ FV AMNA Sbjct: 160 VTEDDVDHEKWTSSRLRVGSQLSRASLLHIALMSSENRAAAALGRNYPGGVAGFVEAMNA 219 Query: 227 KARSLGMMDTHYVDSTGLSSNNVASARDLAKLVVAAYNYPIIRQYSTDAKYMVEPSGHAL 286 KAR+LGM DT +VDS+GLSS N++SA DLAKL AY+ P++RQ+STD K +V SG L Sbjct: 220 KARALGMYDTRFVDSSGLSSKNISSAHDLAKLAAFAYHQPLLRQFSTDPKSVVAASGRTL 279 Query: 287 QYASSNRLVASKDWDIGLQKTGYINEAGHCLVMLTKIEGRSVVMVFLDSKGKLSHVGDAA 346 Y ++N LVAS DWDIGLQKTG+INEAG CLVM I GR+V+MVFLDSKGK S DA Sbjct: 280 NYHNTNYLVASPDWDIGLQKTGFINEAGRCLVMQAMISGRAVIMVFLDSKGKQSRTADAG 339 Query: 347 RMRKWLSEQGPQNL 360 R+++WL P L Sbjct: 340 RVKRWLEALRPAPL 353