BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0021.p (691 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6T0Y8.1 IF2_JANMA Translation initiation factor IF-2 936 0.0 A4G7S7.1 IF2_HERAR Translation initiation factor IF-2 929 0.0 C3X4B8.1 C3X4B8_OXAFO Translation initiation factor IF-2 735 0.0 C3XAH1.1 C3XAH1_OXAFO Translation initiation factor IF-2 728 0.0 D8IQH0.1 D8IQH0_HERSS Translation initiation factor IF-2 679 0.0 >A6T0Y8.1 IF2_JANMA Translation initiation factor IF-2 Length = 937 Score = 936 bits (2420), Expect = 0.0, Method: Compositional matrix adjust. Identities = 510/651 (78%), Positives = 551/651 (84%), Gaps = 27/651 (4%) Query: 1 MASNNVAQFATELKMPADLLLTQLRSAGVEKSSESDPLSKEDKDRLLEHLRRVRGAAPEG 60 MASNNVAQFATELKMPAD+LLTQLR AGVEKSS SD LSK DKD+LL+HLRR G AP+G Sbjct: 1 MASNNVAQFATELKMPADVLLTQLRDAGVEKSSTSDELSKADKDKLLDHLRRAHGVAPDG 60 Query: 61 EKKKITLTRKETTEIKQADSTGKSRTIQVEVRKKRTFIKRDEPTADEAG-KPATASVDQV 119 EKKKITLTRKETTEIKQAD+TGKSRTIQVEVRKKRTF+KRDE T +EA K A +D+ Sbjct: 61 EKKKITLTRKETTEIKQADATGKSRTIQVEVRKKRTFVKRDESTPEEAPVKAAAPVIDEA 120 Query: 120 EAEPSAEEARHQEELIARQEAELREKQERLAQLEAERAAEARAAELEAQKAEQEAKQAAE 179 E E AEEAR Q ELIARQEA+LREKQERLA+LEAE+ A+A+A Sbjct: 121 EIERRAEEARRQAELIARQEADLREKQERLAKLEAEKEAQAKAL---------------- 164 Query: 180 EEARQAAAETADKAKPSAGAAAPVAKSAEDAAADEKKRAAAEEAKKKVAQVAK----EAA 235 AE A+ A AA PV A+++A +EKKR AAEE+KKK AQ+AK EA+ Sbjct: 165 -----KQAEQAEAEAQKADAAKPVEAKADESAQEEKKRVAAEESKKKAAQLAKDAAKEAS 219 Query: 236 DRAAAADRARKVVEDEVAQIKAMMNAPRRVIKAPEPAPVAATKTSEGTLHKPADKKPGEK 295 ++A A + ARK V DEVAQIKAMMNAPRR IKAPEPA A K +EGTLHKPADKK GEK Sbjct: 220 EKAVATEAARKAVADEVAQIKAMMNAPRRAIKAPEPAAPVAAKPAEGTLHKPADKKAGEK 279 Query: 296 KDDKKAPVAVDKKSIKSANVSSTWQDDAKKRGTGMKTRGNTGTGGRDGWRAGPKGRRNSH 355 KD+KK V DKKSIKSANVSSTWQDDAKKRG G+KTRGNTG GGRDGWRAGPKGRR SH Sbjct: 280 KDEKKPAVTADKKSIKSANVSSTWQDDAKKRGAGIKTRGNTG-GGRDGWRAGPKGRRPSH 338 Query: 356 HDDHESNFQAPTEAIVKDVHVPETITVAEIAHKMSVKASEVIKHLMKLGQMVTINQVLDQ 415 HDD ESNFQAPTEA+VKDVHVPETITVAE+AHKMSVKASEVIKHLMKLGQM TINQVLDQ Sbjct: 339 HDDRESNFQAPTEAVVKDVHVPETITVAELAHKMSVKASEVIKHLMKLGQMCTINQVLDQ 398 Query: 416 ETAMIVVEEMGHRAHAAKQDDPEALLEEGVEHPDAELLARAPVVTVMGHVDHGKTSLLDY 475 ETAMI+VEEMGH AHAAK DDPEALLE+G EH D E L RAPVVTVMGHVDHGKTSLLDY Sbjct: 399 ETAMILVEEMGHTAHAAKLDDPEALLEQGEEHADIEALPRAPVVTVMGHVDHGKTSLLDY 458 Query: 476 IRRAKVASGEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVA 535 IRRAKVASGEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVA Sbjct: 459 IRRAKVASGEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVA 518 Query: 536 ADDGVMPQTKEAIAHAKAGGVPLVVAINKIDKQGANLDRVKQELIAEGVVPEEYGGEAPF 595 ADDGVMPQTKEAIAHAKA GVPLVVAINKIDK GAN+DRVKQELIAE VVPEEYGG++PF Sbjct: 519 ADDGVMPQTKEAIAHAKAAGVPLVVAINKIDKPGANMDRVKQELIAEQVVPEEYGGDSPF 578 Query: 596 ISVSAKTGEGIDSLLENVLLQAEVLELKAAINVPAKGLVIEAKLDKGRGPC 646 + VSAKTGEGID+LLE VLLQAEVLELKA ++ PA+GLV+EAKLDKGRGP Sbjct: 579 VPVSAKTGEGIDALLEQVLLQAEVLELKAPVDAPARGLVVEAKLDKGRGPV 629 >A4G7S7.1 IF2_HERAR Translation initiation factor IF-2 Length = 941 Score = 929 bits (2402), Expect = 0.0, Method: Compositional matrix adjust. Identities = 503/656 (76%), Positives = 544/656 (82%), Gaps = 33/656 (5%) Query: 1 MASNNVAQFATELKMPADLLLTQLRSAGVEKSSESDPLSKEDKDRLLEHLRRVRGAAPEG 60 MASNNVAQFATELKMPAD+LLTQLR AGVEKSS SD LSK DKD+LLEHLRR G AP+G Sbjct: 1 MASNNVAQFATELKMPADVLLTQLRDAGVEKSSTSDELSKADKDKLLEHLRRAHGVAPDG 60 Query: 61 EKKKITLTRKETTEIKQADSTGKSRTIQVEVRKKRTFIKRDEPTADEAGKPATAS---VD 117 EKKKITL RKETTEIKQAD+TGKSRTIQVEVRKKRTF+KRDEP A+EA P + +D Sbjct: 61 EKKKITLMRKETTEIKQADATGKSRTIQVEVRKKRTFVKRDEPAAEEA--PVVVAAPIID 118 Query: 118 QVEAEPSAEEARHQEELIARQEAELREKQERLAQLEAERAAEARA---AELEAQKAEQEA 174 E E AEE+R EL+ARQEA+LREKQERLA+LEAE+ +A+A AE++AQKAE +A Sbjct: 119 AAEVERRAEESRRHAELMARQEADLREKQERLAKLEAEKETQAKALKKAEVDAQKAEVDA 178 Query: 175 KQAAEEEARQAAAETADKAKPSAGAAAPVAKSAEDAAADEKKRAAAEEAKKKVAQVAKEA 234 ++A E+ PV A+++A +EKKR AAEE+KKK A AKEA Sbjct: 179 QKAEAEK--------------------PVEVKADESAIEEKKRVAAEESKKKAAAAAKEA 218 Query: 235 ADRAAA----ADRARKVVEDEVAQIKAMMNAPRRVIKAPEPAPVAATKTSEGTLHKPADK 290 A A + ARKVV DEVAQIKAMMNAPRR IKAPEP A +EGTLHKPADK Sbjct: 219 AKEANEKAAATELARKVVADEVAQIKAMMNAPRRAIKAPEPVAPVAKPAAEGTLHKPADK 278 Query: 291 KPGEKKDDKKAPVAVDKKSIKSANVSSTWQDDAKKRGTGMKTRGNTGTGGRDGWRAGPKG 350 KPGEKKD+KK V DKKSIKSANVSSTWQDDAKKR G+KTRGNTG GGRDGWRAG KG Sbjct: 279 KPGEKKDEKKPAVTADKKSIKSANVSSTWQDDAKKRSAGIKTRGNTG-GGRDGWRAGTKG 337 Query: 351 RRNSHHDDHESNFQAPTEAIVKDVHVPETITVAEIAHKMSVKASEVIKHLMKLGQMVTIN 410 RR SHHDD ESNFQAPTEA+VKDV VPETITVAE+AHKMSVKASEVIK LMKLGQM TIN Sbjct: 338 RRQSHHDDRESNFQAPTEAVVKDVQVPETITVAELAHKMSVKASEVIKQLMKLGQMCTIN 397 Query: 411 QVLDQETAMIVVEEMGHRAHAAKQDDPEALLEEGVEHPDAELLARAPVVTVMGHVDHGKT 470 QVLDQETAMI+VEEMGH AHAAK DDPEALLE G E D E L RAPVVTVMGHVDHGKT Sbjct: 398 QVLDQETAMILVEEMGHVAHAAKLDDPEALLEIGAEQADVEALPRAPVVTVMGHVDHGKT 457 Query: 471 SLLDYIRRAKVASGEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIV 530 SLLDYIRRAKVA+GEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIV Sbjct: 458 SLLDYIRRAKVATGEAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIV 517 Query: 531 ILVVAADDGVMPQTKEAIAHAKAGGVPLVVAINKIDKQGANLDRVKQELIAEGVVPEEYG 590 ILVVAADDGVMPQTKEAIAHAKA GVPLVVAINKIDK ANLDRVKQELIAE VVPEEYG Sbjct: 518 ILVVAADDGVMPQTKEAIAHAKAAGVPLVVAINKIDKPSANLDRVKQELIAEQVVPEEYG 577 Query: 591 GEAPFISVSAKTGEGIDSLLENVLLQAEVLELKAAINVPAKGLVIEAKLDKGRGPC 646 G++PF+ VSAKTGEGID+LLE VLLQAEVLELKA + PA+GLV+EAKLDKGRGP Sbjct: 578 GDSPFVPVSAKTGEGIDALLEQVLLQAEVLELKAPVVSPARGLVVEAKLDKGRGPV 633 >C3X4B8.1 C3X4B8_OXAFO Translation initiation factor IF-2 Length = 979 Score = 735 bits (1898), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/675 (63%), Positives = 501/675 (74%), Gaps = 33/675 (4%) Query: 1 MASNNVAQFATELKMPADLLLTQLRSAGVEKSSESDPLSKEDKDRLLEHLRRVRGAAPEG 60 MA NNVAQFA EL +P+D+LL QLR AGVEK+S +D LSKEDKD+LL +LR V GA P G Sbjct: 1 MAINNVAQFAAELNVPSDMLLKQLRDAGVEKNSVNDTLSKEDKDKLLSYLRGVHGA-PAG 59 Query: 61 EKKKITLTRKETTEIKQADSTGKSRTIQVEVRKKRTFIKRDEP---TADEAGKPATASVD 117 EK+KI+LTRKET+EIKQAD+TGKSRTIQVEVRKKRTF+KRDEP + E + +D Sbjct: 60 EKRKISLTRKETSEIKQADATGKSRTIQVEVRKKRTFVKRDEPALRSEVEQRRAVPPVID 119 Query: 118 QVEAEPSAEEARHQEELIARQEAELREKQERLAQLEAERAAEARAAELEAQKAEQEAKQA 177 + E + AEEAR Q ELIARQEAELREKQ +LA++E E+ +AR E + E EA + Sbjct: 120 EAEKQRRAEEARRQAELIARQEAELREKQAQLARMEEEK--QARLRAEEEARNEAEALKR 177 Query: 178 AEEEARQAA------AETADKAKPSAGAAAPVAKSAEDAAADEKKRAAAEEAKKKVAQVA 231 E E R+A AE +K K A A A A + A A+K + Sbjct: 178 KEAEQREAVLKMQREAEQTEKEKQQMAAEEREAAEALKKAEMARMAEEAARAEKARKEAE 237 Query: 232 KEAADRAAAADRARKVVEDEVAQIKAMMNAPRRVIKAPEPAPVA-------------ATK 278 E RA A+RARK VEDEVAQIKAMM+ R+V+K P A A K Sbjct: 238 AERIRRAEEAERARKAVEDEVAQIKAMMSGARKVVKQPAKPVAAPAAPASATADNRDAAK 297 Query: 279 TSEGTLHKPADKKPGEKKDDKKAPVAV--DKKSI--KSANVSSTWQDDAKKRGTGMKTRG 334 + GTL +PA ++ + D K AP DKKS K A ++ W++ KKRG+G+KTRG Sbjct: 298 KAAGTLSRPAQQQTAKPADKKPAPAPAKGDKKSSGDKKAAKTAGWEESGKKRGSGLKTRG 357 Query: 335 NTGTGGRDGWRA---GPKGRRNSHHDDHESNFQAPTEAIVKDVHVPETITVAEIAHKMSV 391 T GRDGWR+ G KGRR++ + ESNF PTEAIV DV+VPETITVAE+AHKM+V Sbjct: 358 GD-TSGRDGWRSSLGGSKGRRHAQLAERESNFHQPTEAIVHDVYVPETITVAELAHKMAV 416 Query: 392 KASEVIKHLMKLGQMVTINQVLDQETAMIVVEEMGHRAHAAKQDDPEALLEEGVEHPDAE 451 KASEVIK LMKLGQMVTINQVLDQETAMI+VEEMGHRA AA+ D E+ LEE + +AE Sbjct: 417 KASEVIKQLMKLGQMVTINQVLDQETAMILVEEMGHRAFAARIQDVESQLEEIGRNDNAE 476 Query: 452 LLARAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETPRGMITFLDTP 511 LL RAPVVTVMGHVDHGKTSLLDYIRR K+ASGEAGGITQHIGAYHV+T RG++TFLDTP Sbjct: 477 LLPRAPVVTVMGHVDHGKTSLLDYIRRTKIASGEAGGITQHIGAYHVKTERGIVTFLDTP 536 Query: 512 GHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAGGVPLVVAINKIDKQGAN 571 GHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKA GVP+VVAINK+DKQGAN Sbjct: 537 GHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPIVVAINKVDKQGAN 596 Query: 572 LDRVKQELIAEGVVPEEYGGEAPFISVSAKTGEGIDSLLENVLLQAEVLELKAAINVPAK 631 ++RV QEL+AE V+PEEYGG++PF+ VSAKTG+GIDSLLENVLLQAE+LELKA + AK Sbjct: 597 INRVTQELVAEQVMPEEYGGDSPFVPVSAKTGQGIDSLLENVLLQAEILELKAPVEAMAK 656 Query: 632 GLVIEAKLDKGRGPC 646 G+VIEA+LDKGRGP Sbjct: 657 GIVIEARLDKGRGPV 671 >C3XAH1.1 C3XAH1_OXAFO Translation initiation factor IF-2 Length = 980 Score = 728 bits (1880), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/678 (62%), Positives = 499/678 (73%), Gaps = 38/678 (5%) Query: 1 MASNNVAQFATELKMPADLLLTQLRSAGVEKSSESDPLSKEDKDRLLEHLRRVRGAAPEG 60 MA+NNVAQFA EL MP+D+LL QLR AGV+K+S D LSKEDKD+LL LR G+ P G Sbjct: 1 MATNNVAQFAAELNMPSDVLLKQLRDAGVDKNSADDILSKEDKDKLLSFLRGSHGS-PSG 59 Query: 61 EKKKITLTRKETTEIKQADSTGKSRTIQVEVRKKRTFIKRDEPTADEAG---KPATASVD 117 EK+KI+LTRKETTEIKQAD+TGKSRTIQVEVRKKRTF KR+E A A + +D Sbjct: 60 EKRKISLTRKETTEIKQADATGKSRTIQVEVRKKRTFDKREEQAAHMAAAERRVVPPVID 119 Query: 118 QVEAEPSAEEARHQEELIARQEAELREKQERLAQLEAERAAEARAAEL------EAQKAE 171 + E + AEEAR Q ELIARQEAELREKQ LAQ+EAE+ +A E E +K E Sbjct: 120 EAEKQRRAEEARRQAELIARQEAELREKQALLAQMEAEKQERIKAEEQARIEAEELKKKE 179 Query: 172 QEAKQAAEEEARQAAAETADKAKPSAGAAAPVAKSAEDAAADEKKRAAAEEAKKKVAQVA 231 E ++AAE+ RQ E AK A A A A + A +A+K + Sbjct: 180 TEQREAAEK-MRQDT-ERQKMAKQQLAAEEKEAAEALKKAEMARMAEEAAQAEKARTEAE 237 Query: 232 KEAADRAAAADRARKVVEDEVAQIKAMMN--APRRVIKAPEPAPVAAT------KTSEGT 283 E RA A+RARK VEDEVAQIKAMM+ A R+V+K PE A + + GT Sbjct: 238 AERVRRAEEAERARKAVEDEVAQIKAMMSTSASRKVVKQPEKPAAAPAGSSPASQKNAGT 297 Query: 284 LHKPADKKPGEKKDDKKA-----------PVAVDKKSIKSANVSSTWQDD-AKKRGTGMK 331 + KPA +P + K +K + DKK+ K+A STWQ++ AKKRG G+K Sbjct: 298 ISKPAQARPAQDKPAEKKAAPAADKKTEKKTSADKKATKTA---STWQEEGAKKRGAGLK 354 Query: 332 TRGNTGTGGRDGWRA---GPKGRRNSHHDDHESNFQAPTEAIVKDVHVPETITVAEIAHK 388 +RGN +G GWR+ GPKGRR++ + ESNF PTEAIV DV+VPETITVAE+AHK Sbjct: 355 SRGNDMSGRDGGWRSSSGGPKGRRHAQVAERESNFHQPTEAIVHDVYVPETITVAELAHK 414 Query: 389 MSVKASEVIKHLMKLGQMVTINQVLDQETAMIVVEEMGHRAHAAKQDDPEALLEEGVEHP 448 M+VKASEVIK LMKLGQMVTINQVLDQETAMI+VEEMGH+A AAK D EA L E ++ Sbjct: 415 MAVKASEVIKQLMKLGQMVTINQVLDQETAMILVEEMGHKAFAAKIQDVEAELAEMGDNE 474 Query: 449 DAELLARAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETPRGMITFL 508 +AELL RAPVVTVMGHVDHGKTSLLDYIRR KVA+GEAGGITQHIGAYHV+T RG++TFL Sbjct: 475 NAELLPRAPVVTVMGHVDHGKTSLLDYIRRTKVATGEAGGITQHIGAYHVKTGRGIVTFL 534 Query: 509 DTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAGGVPLVVAINKIDKQ 568 DTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKA GVP+VVAINKIDKQ Sbjct: 535 DTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPIVVAINKIDKQ 594 Query: 569 GANLDRVKQELIAEGVVPEEYGGEAPFISVSAKTGEGIDSLLENVLLQAEVLELKAAINV 628 GAN++RV QEL+AE V+PEEYGG+ PF+ VSAK+G+GIDSLLENVLLQAE+LEL A + Sbjct: 595 GANVNRVTQELVAEDVIPEEYGGDIPFVPVSAKSGQGIDSLLENVLLQAEILELTAPVEA 654 Query: 629 PAKGLVIEAKLDKGRGPC 646 AKGLVIEA+LDKGRGP Sbjct: 655 MAKGLVIEARLDKGRGPV 672 >D8IQH0.1 D8IQH0_HERSS Translation initiation factor IF-2 Length = 954 Score = 679 bits (1752), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/402 (90%), Positives = 371/402 (92%), Gaps = 4/402 (0%) Query: 248 VEDEVAQIKAMMNAPRRVIKAPEPAPVAATKTSEGTLHKPADK-KPGEKKDDKKAPVAVD 306 VEDEVAQIKAMMNAPRRVIKAPEPA AA KTSEGTLHKPA KPGEKKDDKK VA D Sbjct: 246 VEDEVAQIKAMMNAPRRVIKAPEPA-PAAAKTSEGTLHKPATAAKPGEKKDDKKPAVAAD 304 Query: 307 KKSIKSANVSSTWQDDAKKRGTG-MKTRGNTGTGGRDGWRAGPKGRRNSHHDDH-ESNFQ 364 KKSIKSANVSSTWQDDAKKRGTG MK+RG TG GGRDGWRAGPKGRR+SH DD ESNFQ Sbjct: 305 KKSIKSANVSSTWQDDAKKRGTGGMKSRGATGGGGRDGWRAGPKGRRHSHGDDQRESNFQ 364 Query: 365 APTEAIVKDVHVPETITVAEIAHKMSVKASEVIKHLMKLGQMVTINQVLDQETAMIVVEE 424 PTEA+V DV+VPETITVAE+AHKM+VKASEVIKHLMKLGQMVTINQVLDQETAMIVVEE Sbjct: 365 VPTEAVVHDVYVPETITVAEVAHKMAVKASEVIKHLMKLGQMVTINQVLDQETAMIVVEE 424 Query: 425 MGHRAHAAKQDDPEALLEEGVEHPDAELLARAPVVTVMGHVDHGKTSLLDYIRRAKVASG 484 MGHRAHAAK DDPEALL EG EH DAE L RAPVVTVMGHVDHGKTSLLDYIRR KVASG Sbjct: 425 MGHRAHAAKLDDPEALLVEGEEHGDAEALPRAPVVTVMGHVDHGKTSLLDYIRRTKVASG 484 Query: 485 EAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQT 544 EAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQT Sbjct: 485 EAGGITQHIGAYHVETPRGMITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQT 544 Query: 545 KEAIAHAKAGGVPLVVAINKIDKQGANLDRVKQELIAEGVVPEEYGGEAPFISVSAKTGE 604 KEAIAHAKAGGVPLVVAINKIDK GAN DRVKQELIAE VVPEEYGG+APFI VSAKTGE Sbjct: 545 KEAIAHAKAGGVPLVVAINKIDKPGANPDRVKQELIAEEVVPEEYGGDAPFIPVSAKTGE 604 Query: 605 GIDSLLENVLLQAEVLELKAAINVPAKGLVIEAKLDKGRGPC 646 GIDSLLENVLLQAEVLELKA + VPA+GLVIEAKLDKGRGP Sbjct: 605 GIDSLLENVLLQAEVLELKAPVEVPARGLVIEAKLDKGRGPV 646