BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0001.p (360 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A1WES9.1 A1WES9_VEREI Efflux transporter, RND family, MFP subunit 172 1e-40 D8IWG1.1 D8IWG1_HERSS Membrane-fusion protein 143 5e-32 E6UX89.1 E6UX89_VARPD Efflux transporter, RND family, MFP subunit 135 1e-29 Q1LQT9.1 Q1LQT9_RALME Multidrug resistance protein mdtA (Multidr... 115 1e-23 A8I6M2.1 A8I6M2_AZOC5 Secretion protein 100 3e-19 >A1WES9.1 A1WES9_VEREI Efflux transporter, RND family, MFP subunit Length = 360 Score = 172 bits (435), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 81/100 (81%), Positives = 91/100 (91%), Gaps = 1/100 (1%) Query: 1 VIINQIDPITVQFTLPEEAVPAINRAQLASRKPLKVTAYARTSNE-PLATGTLILLNNQI 59 V+INQIDP+TVQFTLPEEAVPAINRAQ ASR+PLKVTAYAR++N+ PLATG LILLNNQI Sbjct: 185 VVINQIDPMTVQFTLPEEAVPAINRAQRASRQPLKVTAYARSNNDAPLATGQLILLNNQI 244 Query: 60 DTASGTVQLKARFTNQQHVLWPGQYVNVNLQMDDHALSLT 99 DT+SGTVQLKARF N QH LWPGQYVNVNLQM + ++LT Sbjct: 245 DTSSGTVQLKARFANPQHALWPGQYVNVNLQMSERGMALT 284 Score = 112 bits (281), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 56/63 (88%), Positives = 59/63 (93%) Query: 241 NAKIDLQRYTTLRQQDAATQQQLDTQKALVAQLEAAVKTDEAQISYAKVQLGYTTINAPI 300 NA+ DLQRY TLR+QDAATQQQLDTQKALVAQL+AAVKTDEAQI YAKVQLGYTTI API Sbjct: 102 NAQADLQRYMTLRRQDAATQQQLDTQKALVAQLDAAVKTDEAQIKYAKVQLGYTTIKAPI 161 Query: 301 SGR 303 SGR Sbjct: 162 SGR 164 >D8IWG1.1 D8IWG1_HERSS Membrane-fusion protein Length = 403 Score = 143 bits (360), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 68/99 (68%), Positives = 79/99 (79%) Query: 1 VIINQIDPITVQFTLPEEAVPAINRAQLASRKPLKVTAYARTSNEPLATGTLILLNNQID 60 V+INQIDPIT+ FTLPEEAV INRAQ A ++PL+V+AYAR S E LATG L+LL+NQI+ Sbjct: 215 VVINQIDPITLVFTLPEEAVAGINRAQRAHQQPLQVSAYARDSQEVLATGKLVLLDNQIN 274 Query: 61 TASGTVQLKARFTNQQHVLWPGQYVNVNLQMDDHALSLT 99 T +GTVQLKARF N H LWPGQYVN LQM H +LT Sbjct: 275 TTNGTVQLKARFDNPDHKLWPGQYVNARLQMRSHGNALT 313 Score = 123 bits (308), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 61/72 (84%), Positives = 66/72 (91%) Query: 234 RDQAQLTNAKIDLQRYTTLRQQDAATQQQLDTQKALVAQLEAAVKTDEAQISYAKVQLGY 293 +D A L NA++DLQRYTTLR QDAATQQQLDTQKALVAQLEAAVKTDEAQ++YAKVQL Y Sbjct: 125 KDSATLMNARLDLQRYTTLRSQDAATQQQLDTQKALVAQLEAAVKTDEAQVAYAKVQLSY 184 Query: 294 TTINAPISGRVA 305 TTINAPISGRV Sbjct: 185 TTINAPISGRVG 196 >E6UX89.1 E6UX89_VARPD Efflux transporter, RND family, MFP subunit Length = 408 Score = 135 bits (339), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 64/99 (64%), Positives = 72/99 (72%) Query: 1 VIINQIDPITVQFTLPEEAVPAINRAQLASRKPLKVTAYARTSNEPLATGTLILLNNQID 60 V+INQIDPI VQFTLPE++V INR Q S +PL V AY R N+ L G LILLNNQID Sbjct: 216 VVINQIDPIAVQFTLPEDSVQDINRVQQQSNQPLAVVAYDRAGNQMLGAGKLILLNNQID 275 Query: 61 TASGTVQLKARFTNQQHVLWPGQYVNVNLQMDDHALSLT 99 T +GTVQLK F N QH LWPGQYVNV LQ+D +LT Sbjct: 276 TTNGTVQLKGSFANPQHTLWPGQYVNVQLQLDRRQGALT 314 Score = 96.3 bits (238), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 48/73 (65%), Positives = 60/73 (82%) Query: 233 ARDQAQLTNAKIDLQRYTTLRQQDAATQQQLDTQKALVAQLEAAVKTDEAQISYAKVQLG 292 A+D+AQL NA+ DL+RYTTL QDAATQQQLDTQKALV QL A V+TD AQ+ +A+VQL Sbjct: 125 AKDEAQLANARADLKRYTTLIAQDAATQQQLDTQKALVNQLAATVQTDAAQVQFAQVQLS 184 Query: 293 YTTINAPISGRVA 305 +T I +P++GRV Sbjct: 185 FTRIVSPMNGRVG 197 >Q1LQT9.1 Q1LQT9_RALME Multidrug resistance protein mdtA (Multidrug transporter mdtA) Length = 459 Score = 115 bits (288), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 55/91 (60%), Positives = 66/91 (72%) Query: 1 VIINQIDPITVQFTLPEEAVPAINRAQLASRKPLKVTAYARTSNEPLATGTLILLNNQID 60 V+I QIDPI V FTLP++A INRA AS+ PL V A+ R ++ L G LILLNN ID Sbjct: 259 VVIRQIDPIDVVFTLPDDAFGRINRAMQASQSPLVVFAHERGTDADLGHGGLILLNNTID 318 Query: 61 TASGTVQLKARFTNQQHVLWPGQYVNVNLQM 91 T SGT+QLKARF N +H+LWPGQYVN L + Sbjct: 319 TTSGTIQLKARFPNPKHLLWPGQYVNARLVL 349 Score = 96.7 bits (239), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 75/212 (35%), Positives = 104/212 (49%), Gaps = 46/212 (21%) Query: 128 KPMKRRSATPRSSSATPPSTRRSAVATAPTPSYGAIXVVMVIFVFLRNIAATLIP----- 182 +PM R SA+P PP R A+A Y I +V V+++ R + L P Sbjct: 41 RPMSRMSASP------PPRRRPLAIAL-----YVVIAIV-VVWLVARPLGRWLFPPKAPQ 88 Query: 183 ---------------SITVPLAIMGTAAVMYLVGYS--LDNLSLMSAQVQAQQARXKAQL 225 + + L +GT M V +D V+ Q + L Sbjct: 89 ANPAIVVTTAAAQGEDVDIGLTGVGTVQAMQTVTVKPRVDGQLERVGFVEGQDVKEGQVL 148 Query: 226 AQVQAQ------------QARDQAQLTNAKIDLQRYTTLRQQDAATQQQLDTQKALVAQL 273 AQ+ + +ARD+AQL NA++DL+RY L + D+ T+Q LDTQ+ALV QL Sbjct: 149 AQIDPRTFQAQLQQAQATKARDEAQLANARLDLKRYEELIKVDSTTRQTLDTQRALVDQL 208 Query: 274 EAAVKTDEAQISYAKVQLGYTTINAPISGRVA 305 AAV+ DEAQI+ KVQL +TTI AP+SGRV Sbjct: 209 AAAVRNDEAQIALDKVQLDFTTITAPLSGRVG 240 >A8I6M2.1 A8I6M2_AZOC5 Secretion protein Length = 391 Score = 100 bits (250), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 51/82 (62%), Positives = 65/82 (79%) Query: 222 KAQLAQVQAQQARDQAQLTNAKIDLQRYTTLRQQDAATQQQLDTQKALVAQLEAAVKTDE 281 +A LAQ +A +A+D+AQL NAK+DL RY +L +++A ++Q LDTQKALVAQ EAAV+ D+ Sbjct: 104 QAALAQAKATKAKDEAQLANAKLDLDRYASLVEKNATSRQTLDTQKALVAQYEAAVQGDQ 163 Query: 282 AQISYAKVQLGYTTINAPISGR 303 A I A VQLGYTTI API GR Sbjct: 164 AAIDNATVQLGYTTIRAPIDGR 185 Score = 71.6 bits (174), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 34/89 (38%), Positives = 55/89 (61%), Gaps = 2/89 (2%) Query: 1 VIINQIDPITVQFTLPEEAVPAINRAQLASRKPLKVTAYARTSNEPLATGTLILLNNQID 60 V+I+Q+ P++V F LP+E + + A +R P++V AY R + G + L++N I+ Sbjct: 206 VVISQLKPMSVIFALPQERLDEVAAAM--ARGPVEVIAYKRDGVTEVGEGKVELIDNTIN 263 Query: 61 TASGTVQLKARFTNQQHVLWPGQYVNVNL 89 +GT++LKA F N LWPG +VNV + Sbjct: 264 ADTGTLRLKATFPNDNLTLWPGAFVNVKV 292