BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0160.p (347 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYJ2.1 D8IYJ2_HERSS Phosphoribosylformylglycinamidine cyclo-li... 635 e-180 A6T214.1 A6T214_JANMA Phosphoribosylformylglycinamidine cyclo-li... 622 e-176 A4G8B9.2 A4G8B9_HERAR Phosphoribosylformylglycinamidine cyclo-li... 606 e-171 C3XBA8.1 C3XBA8_OXAFO Phosphoribosylformylglycinamidine cyclo-li... 589 e-166 C3X535.1 C3X535_OXAFO Phosphoribosylformylglycinamidine cyclo-li... 576 e-162 >D8IYJ2.1 D8IYJ2_HERSS Phosphoribosylformylglycinamidine cyclo-ligase EC=6.3.3.1 Length = 347 Score = 635 bits (1638), Expect = e-180, Method: Compositional matrix adjust. Identities = 323/347 (93%), Positives = 334/347 (96%) Query: 1 MTSSSNVSLSYRDAGVDIDAGDALVEAIKPFAKRTTREGVLGGIGGFGALFEISKKFKEP 60 MTS SNVSLSYRDAGVDIDAGDALVEAIKPFAKRTTREGVLGGIGGFGALFEISKK+KEP Sbjct: 1 MTSPSNVSLSYRDAGVDIDAGDALVEAIKPFAKRTTREGVLGGIGGFGALFEISKKYKEP 60 Query: 61 VLVSGTDGVGTKLKLAFLLNKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVAS 120 VLVSGTDGVGTKLKLAF LN+HDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDV S Sbjct: 61 VLVSGTDGVGTKLKLAFHLNRHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVPS 120 Query: 121 ATDVIKGIAKGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKLIDGTKIIPG 180 ATDVIKGIA GCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSK+IDGTKI PG Sbjct: 121 ATDVIKGIAAGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKIIDGTKIAPG 180 Query: 181 DVVLGLASSGAHSNGYSLVRKILEVAKPDLNADFHGRKLADVLLEPTRIYVKPLLALMES 240 DVVLGLASSGAHSNGYSLVRKIL+VAKPDL ADFHGRKLADVL+ PTRIYVKPLL+LME Sbjct: 181 DVVLGLASSGAHSNGYSLVRKILDVAKPDLEADFHGRKLADVLMAPTRIYVKPLLSLMEK 240 Query: 241 MEVKGMVHITGGGLVENIPRVLQDNLTAVLDSKAWTMPPLFTWLQQHGGVADAEMHRVFN 300 +EVKGMVHITGGGLVENIPRVLQD+LTA LD+K+WTMPPLFTWLQQHGGVADAEMHRVFN Sbjct: 241 LEVKGMVHITGGGLVENIPRVLQDHLTAELDAKSWTMPPLFTWLQQHGGVADAEMHRVFN 300 Query: 301 CGIGMTVIVSKENAAAAEAQLKAAGETVFRIGEIRARAEGEAQTIVE 347 CGIGMTVIVSKENA AAEA LKAAGETV+RIG IRARAEGEAQTIV Sbjct: 301 CGIGMTVIVSKENADAAEAHLKAAGETVYRIGAIRARAEGEAQTIVR 347 >A6T214.1 A6T214_JANMA Phosphoribosylformylglycinamidine cyclo-ligase EC=6.3.3.1 Length = 347 Score = 622 bits (1605), Expect = e-176, Method: Compositional matrix adjust. Identities = 315/346 (91%), Positives = 330/346 (95%) Query: 1 MTSSSNVSLSYRDAGVDIDAGDALVEAIKPFAKRTTREGVLGGIGGFGALFEISKKFKEP 60 M+S+SN+SLSYRDAGVDIDAGDALVEAIKPFAKRT REGV+GG+GGFGA+FEISKK+KEP Sbjct: 1 MSSNSNISLSYRDAGVDIDAGDALVEAIKPFAKRTMREGVMGGLGGFGAMFEISKKYKEP 60 Query: 61 VLVSGTDGVGTKLKLAFLLNKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVAS 120 VLVSGTDGVGTKLKLAF LN+HDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVA Sbjct: 61 VLVSGTDGVGTKLKLAFELNRHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVAI 120 Query: 121 ATDVIKGIAKGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKLIDGTKIIPG 180 ATDVIKG+AKGCEQAGCALIGGETAEMPSMYP GEYDLAGFAVGAVEKSK+IDGTKI PG Sbjct: 121 ATDVIKGVAKGCEQAGCALIGGETAEMPSMYPAGEYDLAGFAVGAVEKSKIIDGTKIAPG 180 Query: 181 DVVLGLASSGAHSNGYSLVRKILEVAKPDLNADFHGRKLADVLLEPTRIYVKPLLALMES 240 DVVLGLASSGAHSNGYSLVRKI+ VA PDLNADFHGRKLADVL+EPTRIYVKPLLALM + Sbjct: 181 DVVLGLASSGAHSNGYSLVRKIISVANPDLNADFHGRKLADVLMEPTRIYVKPLLALMAA 240 Query: 241 MEVKGMVHITGGGLVENIPRVLQDNLTAVLDSKAWTMPPLFTWLQQHGGVADAEMHRVFN 300 MEVKGMVHITGGGLVENIPRVLQ +LTAVLDS AW MPPLF WLQQHGGVADAEMHRVFN Sbjct: 241 MEVKGMVHITGGGLVENIPRVLQPHLTAVLDSGAWDMPPLFKWLQQHGGVADAEMHRVFN 300 Query: 301 CGIGMTVIVSKENAAAAEAQLKAAGETVFRIGEIRARAEGEAQTIV 346 CGIGMTVIVSKENA AA AQLKAAGETV RIGEIR RAEG+AQTIV Sbjct: 301 CGIGMTVIVSKENADAAIAQLKAAGETVMRIGEIRERAEGQAQTIV 346 >A4G8B9.2 A4G8B9_HERAR Phosphoribosylformylglycinamidine cyclo-ligase EC=6.3.3.1 Length = 371 Score = 606 bits (1562), Expect = e-171, Method: Compositional matrix adjust. Identities = 313/346 (90%), Positives = 332/346 (95%) Query: 1 MTSSSNVSLSYRDAGVDIDAGDALVEAIKPFAKRTTREGVLGGIGGFGALFEISKKFKEP 60 M+S+SN+SLSYRDAGVDIDAGDALVEAIKPFAKRT REGV+GG+GGFGA+FEISKK+KEP Sbjct: 25 MSSTSNISLSYRDAGVDIDAGDALVEAIKPFAKRTMREGVMGGLGGFGAMFEISKKYKEP 84 Query: 61 VLVSGTDGVGTKLKLAFLLNKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVAS 120 VLVSGTDGVGTKLKLAF+LNKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDV Sbjct: 85 VLVSGTDGVGTKLKLAFMLNKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVPI 144 Query: 121 ATDVIKGIAKGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKLIDGTKIIPG 180 ATDVIKG+AKGCE AGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSK+IDGTKI+PG Sbjct: 145 ATDVIKGVAKGCELAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKIIDGTKIVPG 204 Query: 181 DVVLGLASSGAHSNGYSLVRKILEVAKPDLNADFHGRKLADVLLEPTRIYVKPLLALMES 240 DVVLGLASSGAHSNGYSLVRKI+ VA+PDLNADFHGRKLADVLLEPTRIYVKPLLALM S Sbjct: 205 DVVLGLASSGAHSNGYSLVRKIIAVAQPDLNADFHGRKLADVLLEPTRIYVKPLLALMAS 264 Query: 241 MEVKGMVHITGGGLVENIPRVLQDNLTAVLDSKAWTMPPLFTWLQQHGGVADAEMHRVFN 300 MEVKGMVHITGGGLVENIPRVLQ +LTAVL+S AW MPPLF WLQQHGGV DAEMHRVFN Sbjct: 265 MEVKGMVHITGGGLVENIPRVLQPHLTAVLESSAWDMPPLFKWLQQHGGVDDAEMHRVFN 324 Query: 301 CGIGMTVIVSKENAAAAEAQLKAAGETVFRIGEIRARAEGEAQTIV 346 CGIGMTVIV+KENAAAA AQL+AAGETV +IGEIRAR EG+AQTIV Sbjct: 325 CGIGMTVIVAKENAAAAMAQLQAAGETVMQIGEIRARQEGQAQTIV 370 >C3XBA8.1 C3XBA8_OXAFO Phosphoribosylformylglycinamidine cyclo-ligase EC=6.3.3.1 Length = 347 Score = 589 bits (1518), Expect = e-166, Method: Compositional matrix adjust. Identities = 297/347 (85%), Positives = 319/347 (91%) Query: 1 MTSSSNVSLSYRDAGVDIDAGDALVEAIKPFAKRTTREGVLGGIGGFGALFEISKKFKEP 60 M S++N SLSYRDAGVDIDAGDALVEAIKPFAKRT REGVLGGIGGFGALFEISKK+KEP Sbjct: 1 MNSTTNQSLSYRDAGVDIDAGDALVEAIKPFAKRTMREGVLGGIGGFGALFEISKKYKEP 60 Query: 61 VLVSGTDGVGTKLKLAFLLNKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVAS 120 VLVSGTDGVGTKLKLAF LN+HDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDV + Sbjct: 61 VLVSGTDGVGTKLKLAFHLNRHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVKT 120 Query: 121 ATDVIKGIAKGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKLIDGTKIIPG 180 ATDV+KG+A GCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKLI+GT I+PG Sbjct: 121 ATDVVKGVALGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKLINGTTIVPG 180 Query: 181 DVVLGLASSGAHSNGYSLVRKILEVAKPDLNADFHGRKLADVLLEPTRIYVKPLLALMES 240 DVVLGLASSG HSNG+SLVRKI+EVA PDLNAD GR LAD L+ PTRIYVKPLLALM+S Sbjct: 181 DVVLGLASSGIHSNGFSLVRKIIEVANPDLNADLDGRSLADALMAPTRIYVKPLLALMDS 240 Query: 241 MEVKGMVHITGGGLVENIPRVLQDNLTAVLDSKAWTMPPLFTWLQQHGGVADAEMHRVFN 300 M+VKGM HITGGGLVENIPRVLQ +LTAVL +AW MPPLF+WLQ+HG VAD+EMHRVFN Sbjct: 241 MQVKGMAHITGGGLVENIPRVLQKHLTAVLKKEAWPMPPLFSWLQKHGNVADSEMHRVFN 300 Query: 301 CGIGMTVIVSKENAAAAEAQLKAAGETVFRIGEIRARAEGEAQTIVE 347 CGIGM VIVS+ENA AA AQLK+AGETV+RIGEIR R E QTIVE Sbjct: 301 CGIGMVVIVSRENADAAMAQLKSAGETVYRIGEIRQRTGDEPQTIVE 347 >C3X535.1 C3X535_OXAFO Phosphoribosylformylglycinamidine cyclo-ligase EC=6.3.3.1 Length = 347 Score = 576 bits (1484), Expect = e-162, Method: Compositional matrix adjust. Identities = 289/347 (83%), Positives = 315/347 (90%) Query: 1 MTSSSNVSLSYRDAGVDIDAGDALVEAIKPFAKRTTREGVLGGIGGFGALFEISKKFKEP 60 M+SS+N SLSYRDAGVDIDAGDALV AIKPFA+RT REGVLGGIGGFGALFEI K++EP Sbjct: 1 MSSSTNQSLSYRDAGVDIDAGDALVAAIKPFARRTMREGVLGGIGGFGALFEIGNKYREP 60 Query: 61 VLVSGTDGVGTKLKLAFLLNKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVAS 120 VLVSGTDGVGTKLKLAFLLN+HDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDV + Sbjct: 61 VLVSGTDGVGTKLKLAFLLNRHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGKLDVNT 120 Query: 121 ATDVIKGIAKGCEQAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKLIDGTKIIPG 180 ATDVIKG+A GCEQAGCALIGGETAEMP MYPDGEYDLAGFAVGAVEKS +IDGTKI+PG Sbjct: 121 ATDVIKGVAAGCEQAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSAIIDGTKIVPG 180 Query: 181 DVVLGLASSGAHSNGYSLVRKILEVAKPDLNADFHGRKLADVLLEPTRIYVKPLLALMES 240 DVV+GLASSG HSNGYSLVRKI+EVAKPDL+ADF GR LAD L+ PTRIYVKPLL+LM S Sbjct: 181 DVVIGLASSGIHSNGYSLVRKIVEVAKPDLSADFDGRSLADALMAPTRIYVKPLLSLMSS 240 Query: 241 MEVKGMVHITGGGLVENIPRVLQDNLTAVLDSKAWTMPPLFTWLQQHGGVADAEMHRVFN 300 +EVKGM HITGGGLVEN+PRVLQ++LTAVL +AW+MPPLF WLQ+HG VAD EMHRVFN Sbjct: 241 IEVKGMAHITGGGLVENVPRVLQNHLTAVLKKEAWSMPPLFNWLQKHGNVADEEMHRVFN 300 Query: 301 CGIGMTVIVSKENAAAAEAQLKAAGETVFRIGEIRARAEGEAQTIVE 347 CGIGM VIVSKENA A + L+ +GETV+RIGEIR R E QTIVE Sbjct: 301 CGIGMVVIVSKENADKAVSALEISGETVYRIGEIRQRIGNEPQTIVE 347