BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0148.p (401 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYK2.1 D8IYK2_HERSS Membrane transport protein 667 0.0 A6T209.1 A6T209_JANMA Sodium:solute symporter family protein 586 e-165 A4G8B8.1 A4G8B8_HERAR Putative Na+/solute symporter 564 e-158 F1VW22.1 F1VW22_9BURK Sodium:solute symporter family protein 563 e-158 Q124K6.1 Q124K6_POLSJ Na+/solute symporter 467 e-129 >D8IYK2.1 D8IYK2_HERSS Membrane transport protein Length = 683 Score = 667 bits (1722), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/395 (81%), Positives = 361/395 (91%), Gaps = 3/395 (0%) Query: 1 MESDKSFFWRLTRYYSWYTVGFILFLLVLAVLEHEGMPRAWIGYLFMFVTIALYAGIGVV 60 MES+K FF RL RYY +YT+GFI FL VLA+LE EGMPR WIGYLF+FVTI LYAGIGVV Sbjct: 1 MESNKDFFRRLCRYYGFYTLGFIAFLCVLAILEREGMPRTWIGYLFLFVTIGLYAGIGVV 60 Query: 61 SRTSDVPEYYVAGRRVPALFNGMATAADWISAATFISLAGGLYLQGFDGLAYIMGWTGGY 120 RTSDVPEYYVAGRRVP LFNGMATAADWISAATFISLAGGLYLQGFDGLAYI+GWTGGY Sbjct: 61 CRTSDVPEYYVAGRRVPPLFNGMATAADWISAATFISLAGGLYLQGFDGLAYILGWTGGY 120 Query: 121 CLVALLIAPYLRKFGQYTIPDFLAERYPGRYSG---NLVRILAVIATIIISFTYVVAQIY 177 CLVALLIAPYLRKFGQYTI DFLA RYPGR N++RILAV ATI+ISFTYVVAQIY Sbjct: 121 CLVALLIAPYLRKFGQYTIADFLAARYPGRPGSQGVNVIRILAVAATILISFTYVVAQIY 180 Query: 178 GVGLITSRFTGIDFSIGIFLGLASILVCSFLGGMRAITWTQVAQYIIILFAYLIPVIWLS 237 GVGLITSRFTGIDFSIGIFLGLASILVCSFLGGMRAITWTQVAQYIIIL AYLIPVIWLS Sbjct: 181 GVGLITSRFTGIDFSIGIFLGLASILVCSFLGGMRAITWTQVAQYIIILLAYLIPVIWLS 240 Query: 238 AKHTSVPVPQVAYGSVLPKLNAAEKRIADDPKEKEVSAIFQAHADDYEKKLRSLPRSWEE 297 AKHT+VPVP VAYG+VLPKL+A E+R+ DDPKEKE+ IFQA ADDYE+KLR+LP+SW + Sbjct: 241 AKHTTVPVPPVAYGAVLPKLSAIEQRLEDDPKEKEIRKIFQARADDYERKLRNLPQSWVD 300 Query: 298 GRIDAQHHIEEVKRNSHASLAEIKSASRALTAYPKSAEDAERKWTDAKAYNIARAQPPVS 357 GR++A + ++V+R++HASLAEIK+ASRAL++YPKS E+AERKWT+A+A N+ARAQPPVS Sbjct: 301 GRLEAHTNADQVRRDNHASLAEIKAASRALSSYPKSPEEAERKWTEARAANLARAQPPVS 360 Query: 358 QTEPFPGKDEGAANIKRNNFLALVFCLMVGTAALP 392 QTEPFPG+D+ +++IKRNNFLALVFCLM+GTAALP Sbjct: 361 QTEPFPGRDQESSDIKRNNFLALVFCLMLGTAALP 395 >A6T209.1 A6T209_JANMA Sodium:solute symporter family protein Length = 679 Score = 586 bits (1511), Expect = e-165, Method: Compositional matrix adjust. Identities = 280/392 (71%), Positives = 327/392 (83%), Gaps = 1/392 (0%) Query: 1 MESDKSFFWRLTRYYSWYTVGFILFLLVLAVLEHEGMPRAWIGYLFMFVTIALYAGIGVV 60 M K+FF RL RYY YTVGF+LFL +A+LEHEG PR WIGY+FMF TI +YA IGV+ Sbjct: 1 MTKAKTFFQRLCRYYLLYTVGFVLFLFGVAILEHEGFPRVWIGYVFMFSTIVVYATIGVI 60 Query: 61 SRTSDVPEYYVAGRRVPALFNGMATAADWISAATFISLAGGLYLQGFDGLAYIMGWTGGY 120 SRTSDV EYYVAGRRVPA FNGMATAADWISAA+FISLAGGLYL GFDGLAYIMGWTGG+ Sbjct: 61 SRTSDVLEYYVAGRRVPAFFNGMATAADWISAASFISLAGGLYLWGFDGLAYIMGWTGGF 120 Query: 121 CLVALLIAPYLRKFGQYTIPDFLAERYPGRYSGNLVRILAVIATIIISFTYVVAQIYGVG 180 LVALLIAPYLRKFGQYTIPD+LA RY G+YS N+VR++AVIATII+SFTYVVAQIYGVG Sbjct: 121 VLVALLIAPYLRKFGQYTIPDYLAARYTGQYSTNVVRVIAVIATIIVSFTYVVAQIYGVG 180 Query: 181 LITSRFTGIDFSIGIFLGLASILVCSFLGGMRAITWTQVAQYIIILFAYLIPVIWLSAKH 240 LITSRFTG+DFS+GIFLGLASILVCSFLGGMRA+TWTQVAQYII++ AY+IPV+WLS KH Sbjct: 181 LITSRFTGVDFSVGIFLGLASILVCSFLGGMRAVTWTQVAQYIILIIAYMIPVVWLSMKH 240 Query: 241 TSVPVPQVAYGSVLPKLNAAEKRIADDPKEKEVSAIFQAHADDYEKKLRSLPRSWEEGRI 300 T++PVP +AYGS + +L EK + DDPKEKEV AIF+ A D + +L SLP SWE GR Sbjct: 241 TNMPVPPIAYGSAIAQLTEREKVLIDDPKEKEVRAIFRQRAYDLDDRLASLPESWENGRA 300 Query: 301 DAQHHIEEVKRNSHASLAEIKSASRALTAYPKSAEDAERKWTDAKAYNIARAQPPVSQTE 360 + QH++E +K +A+L +IK R L AYP+ A++AER W + +A N+ A+PP TE Sbjct: 301 EIQHNLEALKLG-NAALQDIKQTGRELAAYPRDADEAERVWKEERALNLELAKPPTRHTE 359 Query: 361 PFPGKDEGAANIKRNNFLALVFCLMVGTAALP 392 PFPG E A+NIKRNNFLALVFCLM+GTAALP Sbjct: 360 PFPGDSEEASNIKRNNFLALVFCLMLGTAALP 391 >A4G8B8.1 A4G8B8_HERAR Putative Na+/solute symporter Length = 678 Score = 564 bits (1453), Expect = e-158, Method: Compositional matrix adjust. Identities = 272/388 (70%), Positives = 321/388 (82%), Gaps = 1/388 (0%) Query: 5 KSFFWRLTRYYSWYTVGFILFLLVLAVLEHEGMPRAWIGYLFMFVTIALYAGIGVVSRTS 64 K+FF RL RYY +T+ F+LFL +A+LE EG PRAWIGY+FMF TI +YA IGV+SRTS Sbjct: 4 KAFFRRLMRYYVLFTICFVLFLFAVAILEREGFPRAWIGYVFMFCTIVMYATIGVISRTS 63 Query: 65 DVPEYYVAGRRVPALFNGMATAADWISAATFISLAGGLYLQGFDGLAYIMGWTGGYCLVA 124 ++ EYYVAGRRVPA FNGMATAADWISAA+FISLAGGLYL GFDGLAY+MGWTGG+ LVA Sbjct: 64 NMLEYYVAGRRVPAFFNGMATAADWISAASFISLAGGLYLWGFDGLAYLMGWTGGFVLVA 123 Query: 125 LLIAPYLRKFGQYTIPDFLAERYPGRYSGNLVRILAVIATIIISFTYVVAQIYGVGLITS 184 LLIAPYLRKFGQYTIPD+LA RY GRYS N+VRI+AVIATI++SFTYVVAQIYGVGLITS Sbjct: 124 LLIAPYLRKFGQYTIPDYLAARYTGRYSDNVVRIIAVIATILVSFTYVVAQIYGVGLITS 183 Query: 185 RFTGIDFSIGIFLGLASILVCSFLGGMRAITWTQVAQYIIILFAYLIPVIWLSAKHTSVP 244 RFTG+DFS+GIFLGLASILVCSFLGGMRA+TWTQVAQYIII+ AY+IPV+WLS KHT++P Sbjct: 184 RFTGVDFSVGIFLGLASILVCSFLGGMRAVTWTQVAQYIIIIIAYMIPVVWLSVKHTNIP 243 Query: 245 VPQVAYGSVLPKLNAAEKRIADDPKEKEVSAIFQAHADDYEKKLRSLPRSWEEGRIDAQH 304 VP +AYGS + KL+ E + +DPKEK V AIF A D ++KL+ LP SWE GR + QH Sbjct: 244 VPPIAYGSAIAKLSERETVLINDPKEKGVRAIFHQRAQDLDEKLQMLPESWESGRAEIQH 303 Query: 305 HIEEVKRNSHASLAEIKSASRALTAYPKSAEDAERKWTDAKAYNIARAQPPVSQTEPFPG 364 ++E +K +A L EIK R L YPK E+AER+W + +A N A+PP TEPFPG Sbjct: 304 NLEALKLG-NAPLLEIKQTVRELATYPKDPEEAERRWIEDRAANRELAKPPTRHTEPFPG 362 Query: 365 KDEGAANIKRNNFLALVFCLMVGTAALP 392 E A++IKRNNF+ALVFCLM+GTAALP Sbjct: 363 DTEEASDIKRNNFMALVFCLMLGTAALP 390 >F1VW22.1 F1VW22_9BURK Sodium:solute symporter family protein Length = 679 Score = 563 bits (1450), Expect = e-158, Method: Compositional matrix adjust. Identities = 263/390 (67%), Positives = 323/390 (82%), Gaps = 1/390 (0%) Query: 3 SDKSFFWRLTRYYSWYTVGFILFLLVLAVLEHEGMPRAWIGYLFMFVTIALYAGIGVVSR 62 + +SF RL YY W+TV F+LFLL LA+LE EGMPR WIGYLF+F TI +YAGIGV+SR Sbjct: 2 TTRSFSSRLKIYYGWFTVCFVLFLLALAILEKEGMPRIWIGYLFLFATIVMYAGIGVISR 61 Query: 63 TSDVPEYYVAGRRVPALFNGMATAADWISAATFISLAGGLYLQGFDGLAYIMGWTGGYCL 122 T+DV EYYVAGRRVPA+FNGMATAADW+SAA+F+SLAGGLYLQGFDGLAY+MGWTGG+ L Sbjct: 62 TADVSEYYVAGRRVPAIFNGMATAADWMSAASFLSLAGGLYLQGFDGLAYVMGWTGGFVL 121 Query: 123 VALLIAPYLRKFGQYTIPDFLAERYPGRYSGNLVRILAVIATIIISFTYVVAQIYGVGLI 182 VALL+AP+LRKFGQYT+PD+LA RY GRY ++VR LAVIAT+I+SFTYVVAQIYGVGLI Sbjct: 122 VALLVAPFLRKFGQYTVPDYLAARYGGRYGNDMVRTLAVIATVIVSFTYVVAQIYGVGLI 181 Query: 183 TSRFTGIDFSIGIFLGLASILVCSFLGGMRAITWTQVAQYIIILFAYLIPVIWLSAKHTS 242 TSRFTG+DFS+GIFLGLASILVCSFLGGMRA+TWTQVAQY+I+L AY+IPV+W+S KHTS Sbjct: 182 TSRFTGVDFSVGIFLGLASILVCSFLGGMRAVTWTQVAQYLIMLIAYMIPVVWMSVKHTS 241 Query: 243 VPVPQVAYGSVLPKLNAAEKRIADDPKEKEVSAIFQAHADDYEKKLRSLPRSWEEGRIDA 302 VPVPQVAYG+ L L+ EK + DPKE++V +F+ A + + +L+ LP +W G DA Sbjct: 242 VPVPQVAYGTALSALSEREKVLNADPKEQQVRDVFRQRAAELDLRLQELPAAWSNGLFDA 301 Query: 303 QHHIEEVKRNSHASLAEIKSASRALTAYPKSAEDAERKWTDAKAYNIARAQPPVSQTEPF 362 Q +E++KR+ +A+L +IKSASRAL AYPK A +A + W +++ +ARA P + PF Sbjct: 302 QRRVEQLKRD-NATLIDIKSASRALAAYPKDANEARQVWIESRNNYLARAAPVLPHATPF 360 Query: 363 PGKDEGAANIKRNNFLALVFCLMVGTAALP 392 PG D ++ KRNNFLALV CLM+GTAALP Sbjct: 361 PGTDAATSDSKRNNFLALVLCLMMGTAALP 390 >Q124K6.1 Q124K6_POLSJ Na+/solute symporter Length = 705 Score = 467 bits (1202), Expect = e-129, Method: Compositional matrix adjust. Identities = 231/391 (59%), Positives = 291/391 (74%), Gaps = 5/391 (1%) Query: 2 ESDKSFFWRLTRYYSWYTVGFILFLLVLAVLEHEGMPRAWIGYLFMFVTIALYAGIGVVS 61 +S F L + Y WYT GFI F++VLA+LE G+P+ WIGYLF+ T+ LYAGIGV+S Sbjct: 9 QSQSDFKKGLHKVYGWYTGGFIGFVIVLAILEQLGLPKNWIGYLFLAATVLLYAGIGVMS 68 Query: 62 RTSDVPEYYVAGRRVPALFNGMATAADWISAATFISLAGGLYLQGFDGLAYIMGWTGGYC 121 RTSD EYYVAGRRVPA++NGMAT ADW+SAA+FI +AG LYL G+ GLA+I+GWTGGYC Sbjct: 69 RTSDAAEYYVAGRRVPAMYNGMATGADWMSAASFIGMAGTLYLTGYGGLAFILGWTGGYC 128 Query: 122 LVALLIAPYLRKFGQYTIPDFLAERYPGRYSGNLVRILAVIATIIISFTYVVAQIYGVGL 181 LVAL +APYLRKFGQ+TIPDFL RY GNL R++ V A I+ SFTYVVAQIYGVGL Sbjct: 129 LVALFLAPYLRKFGQFTIPDFLG----ARYEGNLPRLIGVFAAILCSFTYVVAQIYGVGL 184 Query: 182 ITSRFTGIDFSIGIFLGLASILVCSFLGGMRAITWTQVAQYIIILFAYLIPVIWLSAKHT 241 IT+R TG+ F IGIF GL ILVCSFLGGMRA+TWTQVAQY+I++ AYL+PVIWLS KHT Sbjct: 185 ITARLTGLAFEIGIFAGLGGILVCSFLGGMRAVTWTQVAQYVILIIAYLLPVIWLSVKHT 244 Query: 242 SVPVPQVAYGSVLPKLNAAEKRIADDPKEKEVSAIFQAHADDYEKKLRSLPRSWEEGRID 301 VPVPQ YG L K+ A E+++ DPKE EV +F+A ++ KL+ +P + + Sbjct: 245 GVPVPQAVYGYTLQKVTAKEEQLLKDPKELEVRDLFKARSEAAVAKLKDVPAAMAADKAA 304 Query: 302 AQHHIEEVKRNSHASLAEIKSASRALTAYPKSAEDAERKWTDAKAYNIARAQPPVSQTEP 361 AQ ++++K ++ ++A+I++A AL PK A +T A+ N AR+ PP+ +P Sbjct: 305 AQKRLDDLKA-ANGAVADIRAAEAALAGLPKDEAAARAAYTAARVGNAARSAPPIRHAQP 363 Query: 362 FPGKDEGAANIKRNNFLALVFCLMVGTAALP 392 FPGKDE A +I R NFLALVFCLM+GTAALP Sbjct: 364 FPGKDEAAQDISRKNFLALVFCLMIGTAALP 394