BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0125.p (300 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRJ7.1 D8IRJ7_HERSS Permease of the drug/metabolite transporte... 442 e-122 A4G391.1 A4G391_HERAR Putative permease of the drug/metabolite t... 417 e-115 A6SVU3.1 A6SVU3_JANMA Transporter of the DMT superfamily 417 e-114 B2U8Q4.1 B2U8Q4_RALPJ Putative uncharacterized protein 323 2e-86 C6BFF4.1 C6BFF4_RALP1 Putative uncharacterized protein 322 6e-86 >D8IRJ7.1 D8IRJ7_HERSS Permease of the drug/metabolite transporter (DMT) superfamily protein Length = 306 Score = 442 bits (1138), Expect = e-122, Method: Compositional matrix adjust. Identities = 223/288 (77%), Positives = 257/288 (89%) Query: 2 NSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKLP 61 +ES+GMWLG IGVA+FSLTLPFTR+AVAEL+PAFVAFGRAVVA +C++ +L ++A P Sbjct: 19 RNESRGMWLGLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAVVAGLCSLALLAWMRAPRP 78 Query: 62 TRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGERPST 121 Q+RGL+IT+LGVVVGFPLFSSIAM YVPA+HGAVVVGLLPLATALFGALRFGERPS Sbjct: 79 NAQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSA 138 Query: 122 GFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQQVIC 181 GFW++AL GS IVIAFALR GGGSFH ADFALFAAV+ AAMGYAEGGRL+QSMGGQ VI Sbjct: 139 GFWLSALAGSAIVIAFALRAGGGSFHAADFALFAAVITAAMGYAEGGRLAQSMGGQNVIA 198 Query: 182 WALVLSMPVLLPVTIWLGMHYGVAASPQAWMSFAYVSFFSMFIGFFFWYKGLALGGIARV 241 WALV+++PV+LPV++WLG G++AS AW++F YVS FSMFIGFFFWYKGLALGGIARV Sbjct: 199 WALVVALPVMLPVSLWLGWQDGLSASAPAWLAFGYVSLFSMFIGFFFWYKGLALGGIARV 258 Query: 242 GQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMAIRR 289 GQVQLLQPFM+L+GAAVI GE LDAS++LFA AVI VVAIGRRMA+RR Sbjct: 259 GQVQLLQPFMSLLGAAVIAGEALDASNMLFALAVIVVVAIGRRMAVRR 306 >A4G391.1 A4G391_HERAR Putative permease of the drug/metabolite transporter (DMT) Length = 313 Score = 417 bits (1073), Expect = e-115, Method: Compositional matrix adjust. Identities = 209/289 (72%), Positives = 245/289 (84%) Query: 1 MNSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKL 60 M SE+KGMWLG IG+AIFSLTLPFTR+AVAELNP +A GRAVVAA C++ +LW A Sbjct: 23 MTSETKGMWLGAIGIAIFSLTLPFTRMAVAELNPVLMALGRAVVAACCSVLLLWWTNAPR 82 Query: 61 PTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGERPS 120 PTR QV+ LLI + GVVVGFP+FSSIAM ++ ASHGA+++G+LPLATALFGALRFGERPS Sbjct: 83 PTRSQVKSLLIIASGVVVGFPVFSSIAMSHISASHGAIILGILPLATALFGALRFGERPS 142 Query: 121 TGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQQVI 180 GFWI ALIGS +V AFA+ +GGGSF D A+ AV+AAAMGYAEGGRLS+SMGGQQVI Sbjct: 143 LGFWITALIGSALVAAFAVDEGGGSFQWGDLAMLIAVIAAAMGYAEGGRLSESMGGQQVI 202 Query: 181 CWALVLSMPVLLPVTIWLGMHYGVAASPQAWMSFAYVSFFSMFIGFFFWYKGLALGGIAR 240 WALVLSMP++LPVTIWL +HYGV AS AW+ FAYVS FSMFIGFFFWYKGLALGGI+R Sbjct: 203 SWALVLSMPIVLPVTIWLALHYGVQASVSAWVGFAYVSLFSMFIGFFFWYKGLALGGISR 262 Query: 241 VGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMAIRR 289 VGQVQL+QPF+TL+GAAVI+GE L+ LFA A+I VVA+GR+M I+R Sbjct: 263 VGQVQLIQPFLTLLGAAVILGELLEWRTFLFALAIIVVVAMGRKMPIKR 311 >A6SVU3.1 A6SVU3_JANMA Transporter of the DMT superfamily Length = 297 Score = 417 bits (1072), Expect = e-114, Method: Compositional matrix adjust. Identities = 217/289 (75%), Positives = 251/289 (86%) Query: 1 MNSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKL 60 M E+KGM LG IGVA+FSLTLPFTR+AVAEL+P FVA GRAVVAA C+ +LW A L Sbjct: 7 MTQETKGMLLGAIGVALFSLTLPFTRMAVAELDPVFVALGRAVVAAACSAVLLWWTGAVL 66 Query: 61 PTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGERPS 120 P R Q++ L IT+LGVVVGFP+FSSIAMHYVPASHGA+++G+LPLATALFGALRFGERPS Sbjct: 67 PNRTQLKSLFITALGVVVGFPVFSSIAMHYVPASHGAIILGILPLATALFGALRFGERPS 126 Query: 121 TGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQQVI 180 GFWIAA+IGS +V+ FAL+QGGG H AD ALF AV+AAAMGYAEGGRLSQ++GGQQVI Sbjct: 127 PGFWIAAVIGSALVVGFALQQGGGELHIADLALFIAVMAAAMGYAEGGRLSQTLGGQQVI 186 Query: 181 CWALVLSMPVLLPVTIWLGMHYGVAASPQAWMSFAYVSFFSMFIGFFFWYKGLALGGIAR 240 WALVLSMPV+LPVT+WLG +GV+ASP AW FAYVS FSMFIGFFFWYKGLALGGIAR Sbjct: 187 SWALVLSMPVVLPVTVWLGWRHGVSASPAAWAGFAYVSLFSMFIGFFFWYKGLALGGIAR 246 Query: 241 VGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMAIRR 289 VGQVQL+QPF+TL+GAAVI+GE L+ LFA A+IAVVAIGR+M+I+R Sbjct: 247 VGQVQLIQPFLTLLGAAVILGEVLEWRTFLFALAIIAVVAIGRKMSIKR 295 >B2U8Q4.1 B2U8Q4_RALPJ Putative uncharacterized protein Length = 312 Score = 323 bits (828), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 178/299 (59%), Positives = 222/299 (74%), Gaps = 11/299 (3%) Query: 2 NSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHL----K 57 ++E +G+ LG IGVAIFS TLPFTR+AVAEL+ FVA RAV+A+V A+ ML Sbjct: 14 HAERRGLLLGLIGVAIFSQTLPFTRMAVAELDATFVALARAVLASVLALAMLAATGAFSA 73 Query: 58 AKLPTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGE 117 AK P Q L +T++GVVVGFPLFSS+AM VPA+HGA++ GLLPLATA+F A E Sbjct: 74 AKRPRGHQWWQLAVTAMGVVVGFPLFSSLAMRDVPAAHGAIITGLLPLATAIFAAWFGRE 133 Query: 118 RPSTGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQ 177 RPS GFW+ AL GS +V++FAL QG GS H AD+ LFAA+V A+GYA GG+L++ +GG Sbjct: 134 RPSAGFWLCALAGSVLVVSFALLQGAGSLHRADWLLFAAMVTGALGYATGGKLARELGGT 193 Query: 178 QVICWALVLSMPVLLPVT---IWL-GMHYGVA---ASPQAWMSFAYVSFFSMFIGFFFWY 230 Q I WAL++S+PVLLP+ +WL H A AS +AWM AYVS FSMFIGF FWY Sbjct: 194 QTIAWALIVSLPVLLPLVSALVWLPSTHQAEALAHASSRAWMGLAYVSAFSMFIGFLFWY 253 Query: 231 KGLALGGIARVGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMAIRR 289 GLA GG+ARVGQ+QLLQPFMTL+G +++GE+LDA +LFA AVIAVV IGRR ++RR Sbjct: 254 SGLAAGGVARVGQIQLLQPFMTLIGGWLLLGESLDAPTVLFALAVIAVVGIGRRTSVRR 312 >C6BFF4.1 C6BFF4_RALP1 Putative uncharacterized protein Length = 312 Score = 322 bits (824), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 178/299 (59%), Positives = 221/299 (73%), Gaps = 11/299 (3%) Query: 2 NSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKA--- 58 ++E +G+ LG IGVAIFS TLPFTR+AVAEL+ FVA RAV+A+V A+ ML A Sbjct: 14 HAERRGLLLGLIGVAIFSQTLPFTRMAVAELDATFVALARAVLASVLALAMLAATGAFAA 73 Query: 59 -KLPTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGE 117 K P Q L +T++GVVVGFPLFSS+AM VPA+HGA++ GLLPLATA+F A E Sbjct: 74 GKRPRGHQWWQLAVTAMGVVVGFPLFSSLAMRDVPAAHGAIITGLLPLATAIFAAWFGRE 133 Query: 118 RPSTGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQ 177 RPS GFW+ AL GS +V++FAL QG GS H AD+ LFAA+V A+GYA GG+L++ +GG Sbjct: 134 RPSAGFWLCALAGSVLVVSFALLQGAGSLHRADWLLFAAMVTGALGYATGGKLARELGGT 193 Query: 178 QVICWALVLSMPVLLPVT---IWL-GMHYGVA---ASPQAWMSFAYVSFFSMFIGFFFWY 230 Q I WAL++S+PVLLP+ WL H A AS +AWM AYVS FSMFIGF FWY Sbjct: 194 QTIAWALIISLPVLLPLVSALAWLPSTHQAEALAHASSRAWMGLAYVSAFSMFIGFLFWY 253 Query: 231 KGLALGGIARVGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMAIRR 289 GLA GG+ARVGQ+QLLQPFMTL+G +++GE+LDA +LFA AVIAVV IGRR ++RR Sbjct: 254 SGLAAGGVARVGQIQLLQPFMTLIGGWLLLGESLDAPTVLFALAVIAVVGIGRRTSVRR 312