BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0078.p (455 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IZ85.1 D8IZ85_HERSS Adenylosuccinate lyase protein EC=4.3.2.2 867 0.0 A6SUV2.1 A6SUV2_JANMA Adenylosuccinate lyase EC=4.3.2.2 851 0.0 A4G201.2 A4G201_HERAR Adenylosuccinate lyase EC=4.3.2.2 836 0.0 F1W153.1 F1W153_9BURK Adenylosuccinate lyase 813 0.0 D8NYM1.1 D8NYM1_RALSO Adenylosuccinate lyase EC=4.3.2.2 753 0.0 >D8IZ85.1 D8IZ85_HERSS Adenylosuccinate lyase protein EC=4.3.2.2 Length = 455 Score = 867 bits (2240), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/455 (92%), Positives = 439/455 (96%) Query: 1 MSLSALSALSPLDGRYAAKTDKLRPILSEAGFMHHRVKVEIAWLQALSAAGFAEIKPFSA 60 MSLSALSALSPLDGRYA+KTDKLRP+LSEAGFMHHRVKVEIAWLQALS AGFAEIKPFSA Sbjct: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALSEAGFAEIKPFSA 60 Query: 61 SATALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFAC 120 +A ALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFAC Sbjct: 61 TALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFAC 120 Query: 121 TSEDINNTSHGMMLKSARDTVVLPALQGLVAKLTELAHEHAAVPMMSRTHGQPASPTTLG 180 TSEDINNTSHGMMLK+ARDTV+LP+LQ ++ KLTELAHEHAAVPM+SRTHGQPASPTTLG Sbjct: 121 TSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTLG 180 Query: 181 KEIANVVARLQRAVKRIAAVEILGKMNGAVGNYNAHLSAYPETDWAAFSKNVIEQRLGLV 240 KE+ANVVARLQRA KRIAAVEILGKMNGAVGNYNAHLSAYP+TDWAAFSK V+EQRLGLV Sbjct: 181 KEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGLV 240 Query: 241 FNPYTIQIEPHDYMAELFDAVARANTILLDLNRDVWGYISLGYFKQRTKAGEIGSSTMPH 300 FNPYTIQIEPHDYMAELFDAVAR NTILLDLNRD+WGYISLGYFKQRTKAGEIGSSTMPH Sbjct: 241 FNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMPH 300 Query: 301 KVNPIDFENSEGNLGMANAVLKHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYAVLAYDSC 360 KVNPIDFENSEGNLGMANAVLKHL+EKLPVSRWQRDLTDSTVLRNIGV FGY +LAYDSC Sbjct: 301 KVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDSC 360 Query: 361 LRGLNKLEVNPTRLAADLDNTWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALR 420 LRGLNKLEVNP RLA DLD TWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALR Sbjct: 361 LRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALR 420 Query: 421 DFINGLAIPQNAKDHLLAMTPANYIGEAIALAKNI 455 DFINGLAIPQ AKDHLLAMTPANYIG A+ LAK I Sbjct: 421 DFINGLAIPQEAKDHLLAMTPANYIGTAVELAKQI 455 >A6SUV2.1 A6SUV2_JANMA Adenylosuccinate lyase EC=4.3.2.2 Length = 455 Score = 851 bits (2198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/455 (88%), Positives = 430/455 (94%) Query: 1 MSLSALSALSPLDGRYAAKTDKLRPILSEAGFMHHRVKVEIAWLQALSAAGFAEIKPFSA 60 M LS LSALSPLDGRYA+KTDKLRPILSE+GFMHHRVKVEIAWLQALSAAGFAEIKPFSA Sbjct: 1 MPLSTLSALSPLDGRYASKTDKLRPILSESGFMHHRVKVEIAWLQALSAAGFAEIKPFSA 60 Query: 61 SATALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFAC 120 SA ALLDKL DFTEADA RIK+IEAVTNHDVKAVEYWLKE+VKDVPELVAA+EFIHFAC Sbjct: 61 SANALLDKLTTDFTEADAQRIKDIEAVTNHDVKAVEYWLKEQVKDVPELVAATEFIHFAC 120 Query: 121 TSEDINNTSHGMMLKSARDTVVLPALQGLVAKLTELAHEHAAVPMMSRTHGQPASPTTLG 180 TSEDINNTSHGMMLK+ARDTV++PALQGL++KLT+LAH++AAVPMMSRTHGQPASPTTLG Sbjct: 121 TSEDINNTSHGMMLKAARDTVLVPALQGLISKLTQLAHDNAAVPMMSRTHGQPASPTTLG 180 Query: 181 KEIANVVARLQRAVKRIAAVEILGKMNGAVGNYNAHLSAYPETDWAAFSKNVIEQRLGLV 240 KE+ANVVARL+RAV RI AVEILGKMNGAVGN+NAHLSAYP TDW AFSK VIE+RLGL Sbjct: 181 KEMANVVARLKRAVDRIGAVEILGKMNGAVGNFNAHLSAYPNTDWQAFSKEVIEKRLGLT 240 Query: 241 FNPYTIQIEPHDYMAELFDAVARANTILLDLNRDVWGYISLGYFKQRTKAGEIGSSTMPH 300 FNPYTIQIEPHDYMAELFDA+AR NTILLDLNRD+WGYISLGYFKQ TKAGEIGSSTMPH Sbjct: 241 FNPYTIQIEPHDYMAELFDAIARTNTILLDLNRDIWGYISLGYFKQSTKAGEIGSSTMPH 300 Query: 301 KVNPIDFENSEGNLGMANAVLKHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYAVLAYDSC 360 KVNPIDFENSEGNLGMANAVLKH++EKLPVSRWQRDLTDSTVLRNIGV FGYA+LAYDSC Sbjct: 301 KVNPIDFENSEGNLGMANAVLKHMAEKLPVSRWQRDLTDSTVLRNIGVGFGYALLAYDSC 360 Query: 361 LRGLNKLEVNPTRLAADLDNTWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALR 420 LRGLNKLEVNP R+A DLD TWEVLAEPVQTVMRRYGIENPYEQLK+LTRGKGISK+AL+ Sbjct: 361 LRGLNKLEVNPVRIAQDLDETWEVLAEPVQTVMRRYGIENPYEQLKDLTRGKGISKEALQ 420 Query: 421 DFINGLAIPQNAKDHLLAMTPANYIGEAIALAKNI 455 +FI LAIPQ AKDHLLAMTPANYIG A LAK I Sbjct: 421 EFIATLAIPQEAKDHLLAMTPANYIGYATKLAKEI 455 >A4G201.2 A4G201_HERAR Adenylosuccinate lyase EC=4.3.2.2 Length = 455 Score = 836 bits (2159), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/455 (87%), Positives = 425/455 (93%) Query: 1 MSLSALSALSPLDGRYAAKTDKLRPILSEAGFMHHRVKVEIAWLQALSAAGFAEIKPFSA 60 M LSALSALSPLDGRYA KTDKLRPILSEAGFMHHRVKVEIAWLQALS AGFAEIKPFSA Sbjct: 1 MPLSALSALSPLDGRYAVKTDKLRPILSEAGFMHHRVKVEIAWLQALSTAGFAEIKPFSA 60 Query: 61 SATALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFAC 120 SA ALL+KL DFTE DA RIK+IEAVTNHDVKAVEYWLKE+VKDVPELVAA+EFIHFAC Sbjct: 61 SANALLNKLTTDFTEVDAQRIKDIEAVTNHDVKAVEYWLKEQVKDVPELVAATEFIHFAC 120 Query: 121 TSEDINNTSHGMMLKSARDTVVLPALQGLVAKLTELAHEHAAVPMMSRTHGQPASPTTLG 180 TSEDINNTSHGMMLK+ARDTV+LPALQ LVAKLT+LAH++AA+PMMSRTHGQPASPTTLG Sbjct: 121 TSEDINNTSHGMMLKAARDTVMLPALQALVAKLTQLAHDNAALPMMSRTHGQPASPTTLG 180 Query: 181 KEIANVVARLQRAVKRIAAVEILGKMNGAVGNYNAHLSAYPETDWAAFSKNVIEQRLGLV 240 KE+ANVVARL+RA+ RIA V+ILGKMNGAVGN+NAHLSAYP TDW AFSK+VIE RLGL Sbjct: 181 KEMANVVARLKRAIDRIADVQILGKMNGAVGNFNAHLSAYPHTDWQAFSKDVIENRLGLT 240 Query: 241 FNPYTIQIEPHDYMAELFDAVARANTILLDLNRDVWGYISLGYFKQRTKAGEIGSSTMPH 300 FNPYTIQIEPHDYMAELFDA+AR NTILLDLNRD+WGYISLGYFKQ TKAGEIGSSTMPH Sbjct: 241 FNPYTIQIEPHDYMAELFDAIARTNTILLDLNRDIWGYISLGYFKQSTKAGEIGSSTMPH 300 Query: 301 KVNPIDFENSEGNLGMANAVLKHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYAVLAYDSC 360 KVNPIDFENSEGNLGMANAVLKH++EKLP+SRWQRDLTDSTVLRNIGV FGYA+LAYDSC Sbjct: 301 KVNPIDFENSEGNLGMANAVLKHMAEKLPISRWQRDLTDSTVLRNIGVGFGYALLAYDSC 360 Query: 361 LRGLNKLEVNPTRLAADLDNTWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALR 420 LRGLNKLEVNP R+A DLD TWEVLAEPVQTVMRRYGIENPYEQLK+LTRGKGISK+AL+ Sbjct: 361 LRGLNKLEVNPVRIAQDLDETWEVLAEPVQTVMRRYGIENPYEQLKDLTRGKGISKEALQ 420 Query: 421 DFINGLAIPQNAKDHLLAMTPANYIGEAIALAKNI 455 +FI LAIPQ AKD LL MTPANYIG A LA+ I Sbjct: 421 EFIVTLAIPQEAKDLLLTMTPANYIGYASKLAREI 455 >F1W153.1 F1W153_9BURK Adenylosuccinate lyase Length = 455 Score = 813 bits (2101), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/455 (85%), Positives = 419/455 (92%) Query: 1 MSLSALSALSPLDGRYAAKTDKLRPILSEAGFMHHRVKVEIAWLQALSAAGFAEIKPFSA 60 M LS LSALSPLDGRYAAKTD LRPILSE GFMHHRVKVEI WLQAL+ AGF+EI+PFS Sbjct: 1 MPLSPLSALSPLDGRYAAKTDALRPILSETGFMHHRVKVEICWLQALAQAGFSEIQPFSP 60 Query: 61 SATALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFAC 120 +A ALLDKLA DF+EADAARIK IEAVTNHDVKAVEYWLKE+VKDVPELV ASEFIHFAC Sbjct: 61 AAGALLDKLATDFSEADAARIKAIEAVTNHDVKAVEYWLKEQVKDVPELVTASEFIHFAC 120 Query: 121 TSEDINNTSHGMMLKSARDTVVLPALQGLVAKLTELAHEHAAVPMMSRTHGQPASPTTLG 180 TSEDINNTSHGMMLK+AR+ VVLPALQ ++ KLT LAHE+AA+PM+SRTHGQPASPTTLG Sbjct: 121 TSEDINNTSHGMMLKAARNDVVLPALQAVITKLTALAHENAALPMLSRTHGQPASPTTLG 180 Query: 181 KEIANVVARLQRAVKRIAAVEILGKMNGAVGNYNAHLSAYPETDWAAFSKNVIEQRLGLV 240 KEIANVVARL+RA +RIAAVEILGKMNGAVGNYNAHLSAYP DW +FS+ VIEQRLGL Sbjct: 181 KEIANVVARLRRAEQRIAAVEILGKMNGAVGNYNAHLSAYPNFDWESFSREVIEQRLGLT 240 Query: 241 FNPYTIQIEPHDYMAELFDAVARANTILLDLNRDVWGYISLGYFKQRTKAGEIGSSTMPH 300 +NPYTIQIEPHDYMAELFDA+ R NTILLDLNRD+WGYIS+GYFKQR KAGEIGSSTMPH Sbjct: 241 YNPYTIQIEPHDYMAELFDAITRTNTILLDLNRDLWGYISVGYFKQRLKAGEIGSSTMPH 300 Query: 301 KVNPIDFENSEGNLGMANAVLKHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYAVLAYDSC 360 KVNPIDFENSEGNLG+ANA+LKH+S+KLPVSR+QRDLTDSTVLRNIGVAFGY +LAYDSC Sbjct: 301 KVNPIDFENSEGNLGLANAMLKHMSDKLPVSRFQRDLTDSTVLRNIGVAFGYTILAYDSC 360 Query: 361 LRGLNKLEVNPTRLAADLDNTWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALR 420 LRGLNKLEVNP RLA DLD TWEVLAEPVQTVMRRY +EN YEQLKELTRGKGISKDALR Sbjct: 361 LRGLNKLEVNPARLAEDLDATWEVLAEPVQTVMRRYAVENAYEQLKELTRGKGISKDALR 420 Query: 421 DFINGLAIPQNAKDHLLAMTPANYIGEAIALAKNI 455 DFI GLAIPQ+AKD LLAMTP+NYIG A LA+ I Sbjct: 421 DFIVGLAIPQDAKDLLLAMTPSNYIGIAEKLARAI 455 >D8NYM1.1 D8NYM1_RALSO Adenylosuccinate lyase EC=4.3.2.2 Length = 457 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/454 (79%), Positives = 399/454 (87%) Query: 2 SLSALSALSPLDGRYAAKTDKLRPILSEAGFMHHRVKVEIAWLQALSAAGFAEIKPFSAS 61 SLSAL+ALSP+DGRYAAK D LR LSEA FM HRVKVE+ WL ALS AG AEI FSA Sbjct: 3 SLSALTALSPIDGRYAAKADPLREWLSEAAFMRHRVKVEVHWLIALSQAGLAEIPRFSAD 62 Query: 62 ATALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFACT 121 A L L +F EADAARIKEIEAVTNHDVKAVEYWLKE+VK EL AASEFIHFACT Sbjct: 63 AERTLLALVDNFAEADAARIKEIEAVTNHDVKAVEYWLKERVKGNAELEAASEFIHFACT 122 Query: 122 SEDINNTSHGMMLKSARDTVVLPALQGLVAKLTELAHEHAAVPMMSRTHGQPASPTTLGK 181 SEDINNTSHGMMLK ARDTV++P L+ + A+L ELAH +A VPM+SRTHGQPASPTTLGK Sbjct: 123 SEDINNTSHGMMLKGARDTVIVPVLRRVQARLVELAHANADVPMLSRTHGQPASPTTLGK 182 Query: 182 EIANVVARLQRAVKRIAAVEILGKMNGAVGNYNAHLSAYPETDWAAFSKNVIEQRLGLVF 241 E+ANV ARL+RA++R+ AVE+LGKMNGAVGNYNAHLSAYP+ DW AFSKNVIE RLGL F Sbjct: 183 EMANVAARLERAIRRVEAVELLGKMNGAVGNYNAHLSAYPDADWEAFSKNVIESRLGLTF 242 Query: 242 NPYTIQIEPHDYMAELFDAVARANTILLDLNRDVWGYISLGYFKQRTKAGEIGSSTMPHK 301 NPYTIQIEPHDYMAELFDAVARANTI+LDL+RDVWGYIS GYFKQ+TKAGEIGSSTMPHK Sbjct: 243 NPYTIQIEPHDYMAELFDAVARANTIILDLDRDVWGYISQGYFKQKTKAGEIGSSTMPHK 302 Query: 302 VNPIDFENSEGNLGMANAVLKHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYAVLAYDSCL 361 VNPIDFENSEGN+G+ANAVL+HLSEKLPVSRWQRDLTDSTVLRNIGVAFGY++LAYD+CL Sbjct: 303 VNPIDFENSEGNIGLANAVLRHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYSLLAYDACL 362 Query: 362 RGLNKLEVNPTRLAADLDNTWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALRD 421 RGL KLE NP RLA DLD WEVLAEPVQTVMRR+G+ NPYEQLKELTRGKGIS++ALR+ Sbjct: 363 RGLGKLETNPARLAEDLDACWEVLAEPVQTVMRRFGLANPYEQLKELTRGKGISREALRE 422 Query: 422 FINGLAIPQNAKDHLLAMTPANYIGEAIALAKNI 455 FI LAIP+ A+ LL MTP +Y+G+A+ LA+ I Sbjct: 423 FIGTLAIPEAARQQLLDMTPGSYVGKAVELARRI 456