BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0061.p (448 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IZA1.1 D8IZA1_HERSS XAA-PRO aminopeptidase protein EC=3.4.11.9 755 0.0 A2RQ02.1 A2RQ02_HERSE XAA-PRO aminopeptidase protein 755 0.0 A6SV07.1 A6SV07_JANMA X-Pro aminopeptidase EC=3.4.11.9 717 0.0 A4G250.1 A4G250_HERAR Proline aminopeptidase P II (Xaa-Pro amino... 699 0.0 F1VWK4.1 F1VWK4_9BURK Xaa-Pro aminopeptidase 671 0.0 >D8IZA1.1 D8IZA1_HERSS XAA-PRO aminopeptidase protein EC=3.4.11.9 Length = 448 Score = 755 bits (1950), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/444 (83%), Positives = 403/444 (90%), Gaps = 2/444 (0%) Query: 4 ASFIARRASLIAQMQAKGGGVAIIPTAHEVMRNRDADYPYRHDSYFYYLSGFTEPEAVIV 63 + F ARRA L+A +Q GGGVAIIPTA EVMRNRDADYPYRHDSYFYYL+GFTEPEAV+V Sbjct: 6 SPFAARRARLLASLQQAGGGVAIIPTAPEVMRNRDADYPYRHDSYFYYLTGFTEPEAVLV 65 Query: 64 LIAAPGKESRSILFCRDKNLEREIWDGYRYGPDAARQEFGFDEAFAVDTLNKEMPQLLAD 123 L+A GKE+RSILFCRDKNLEREIWDGYR+GP AA+Q F D A ++ L+K MP LL+D Sbjct: 66 LVA--GKENRSILFCRDKNLEREIWDGYRHGPQAAQQLFALDAAHPIEELDKSMPALLSD 123 Query: 124 APAVFYALGRDVKRDAQLQEWLQSVRALGRSGITAPSSIVDVNVLLDEMRLFKDAGEIAV 183 A AV+YALG D KRDAQLQ WLQ VRAL RSG++AP+++VDV+VLLD+MRLFKDA EI V Sbjct: 124 ARAVYYALGHDDKRDAQLQRWLQGVRALARSGVSAPAAVVDVSVLLDDMRLFKDAYEIDV 183 Query: 184 MKRAGLISAEAHCRAMRLSRPGLREYHLEAELLHEFRNNGSQYPAYGSIVATGANACVLH 243 MKRAG+ISAEAHCRAMR+ RPGLREYHLEAELLHEFR NGSQYPAYGSIVATGAN+CVLH Sbjct: 184 MKRAGIISAEAHCRAMRICRPGLREYHLEAELLHEFRRNGSQYPAYGSIVATGANSCVLH 243 Query: 244 YRAGDAELRDGDLVLIDAGCELDSYASDITRTFPANGKFSGPQKELYEIVLAAQDAAIAD 303 YRAGDAE++DGDLVLIDAGCELDSYASDITRTFPANG FSGPQK LYEIVLAAQ AAIA+ Sbjct: 244 YRAGDAEIKDGDLVLIDAGCELDSYASDITRTFPANGAFSGPQKALYEIVLAAQAAAIAE 303 Query: 304 TRPGKRFMDGHDAAVRVLAQGMLDTGLLDKNKVGSLDDVIAKGDYRQFYMHRTGHWLGMD 363 T PGKRFMDGHDAAVRVLAQGMLDTGLLDK+KVGSL+DVI KGDYRQFYMHRTGHWLGMD Sbjct: 304 TAPGKRFMDGHDAAVRVLAQGMLDTGLLDKSKVGSLEDVIEKGDYRQFYMHRTGHWLGMD 363 Query: 364 VHDVGEYRDPATADGDKPWRTLQPGMVLTVEPGIYVRPGEGVPEKYWNIGIRIEDDAHVT 423 VHDVG+YRDPAT DG KPWRTLQPGMVLT+EPGIYVRPGEGVPE++WNIGIRIEDDAHVT Sbjct: 364 VHDVGDYRDPATTDGSKPWRTLQPGMVLTIEPGIYVRPGEGVPEQFWNIGIRIEDDAHVT 423 Query: 424 PDGCEILTTAVPNKVADIEALMRS 447 P GCE+LTT VP KV DIEALMR Sbjct: 424 PSGCELLTTGVPTKVEDIEALMRQ 447 >A2RQ02.1 A2RQ02_HERSE XAA-PRO aminopeptidase protein Length = 448 Score = 755 bits (1950), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/444 (83%), Positives = 403/444 (90%), Gaps = 2/444 (0%) Query: 4 ASFIARRASLIAQMQAKGGGVAIIPTAHEVMRNRDADYPYRHDSYFYYLSGFTEPEAVIV 63 + F ARRA L+A +Q GGGVAIIPTA EVMRNRDADYPYRHDSYFYYL+GFTEPEAV+V Sbjct: 6 SPFAARRARLLASLQQAGGGVAIIPTAPEVMRNRDADYPYRHDSYFYYLTGFTEPEAVLV 65 Query: 64 LIAAPGKESRSILFCRDKNLEREIWDGYRYGPDAARQEFGFDEAFAVDTLNKEMPQLLAD 123 L+A GKE+RSILFCRDKNLEREIWDGYR+GP AA+Q F D A ++ L+K MP LL+D Sbjct: 66 LVA--GKENRSILFCRDKNLEREIWDGYRHGPQAAQQLFALDAAHPIEELDKSMPALLSD 123 Query: 124 APAVFYALGRDVKRDAQLQEWLQSVRALGRSGITAPSSIVDVNVLLDEMRLFKDAGEIAV 183 A AV+YALG D KRDAQLQ WLQ VRAL RSG++AP+++VDV+VLLD+MRLFKDA EI V Sbjct: 124 ARAVYYALGHDDKRDAQLQRWLQGVRALARSGVSAPAAVVDVSVLLDDMRLFKDAYEIDV 183 Query: 184 MKRAGLISAEAHCRAMRLSRPGLREYHLEAELLHEFRNNGSQYPAYGSIVATGANACVLH 243 MKRAG+ISAEAHCRAMR+ RPGLREYHLEAELLHEFR NGSQYPAYGSIVATGAN+CVLH Sbjct: 184 MKRAGIISAEAHCRAMRICRPGLREYHLEAELLHEFRRNGSQYPAYGSIVATGANSCVLH 243 Query: 244 YRAGDAELRDGDLVLIDAGCELDSYASDITRTFPANGKFSGPQKELYEIVLAAQDAAIAD 303 YRAGDAE++DGDLVLIDAGCELDSYASDITRTFPANG FSGPQK LYEIVLAAQ AAIA+ Sbjct: 244 YRAGDAEIKDGDLVLIDAGCELDSYASDITRTFPANGAFSGPQKALYEIVLAAQAAAIAE 303 Query: 304 TRPGKRFMDGHDAAVRVLAQGMLDTGLLDKNKVGSLDDVIAKGDYRQFYMHRTGHWLGMD 363 T PGKRFMDGHDAAVRVLAQGMLDTGLLDK+KVGSL+DVI KGDYRQFYMHRTGHWLGMD Sbjct: 304 TAPGKRFMDGHDAAVRVLAQGMLDTGLLDKSKVGSLEDVIEKGDYRQFYMHRTGHWLGMD 363 Query: 364 VHDVGEYRDPATADGDKPWRTLQPGMVLTVEPGIYVRPGEGVPEKYWNIGIRIEDDAHVT 423 VHDVG+YRDPAT DG KPWRTLQPGMVLT+EPGIYVRPGEGVPE++WNIGIRIEDDAHVT Sbjct: 364 VHDVGDYRDPATTDGSKPWRTLQPGMVLTIEPGIYVRPGEGVPEQFWNIGIRIEDDAHVT 423 Query: 424 PDGCEILTTAVPNKVADIEALMRS 447 P GCE+LTT VP KV DIEALMR Sbjct: 424 PSGCELLTTGVPTKVEDIEALMRQ 447 >A6SV07.1 A6SV07_JANMA X-Pro aminopeptidase EC=3.4.11.9 Length = 443 Score = 717 bits (1852), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/438 (79%), Positives = 389/438 (88%), Gaps = 2/438 (0%) Query: 9 RRASLIAQMQAKGGGVAIIPTAHEVMRNRDADYPYRHDSYFYYLSGFTEPEAVIVLIAAP 68 RRASLIAQMQAKGGG+AIIPTA EVMRNRDADYPYRHDSYFYYLSGFTEPEAVIVL+A Sbjct: 7 RRASLIAQMQAKGGGIAIIPTAPEVMRNRDADYPYRHDSYFYYLSGFTEPEAVIVLVA-- 64 Query: 69 GKESRSILFCRDKNLEREIWDGYRYGPDAARQEFGFDEAFAVDTLNKEMPQLLADAPAVF 128 G ++++ILFCR+KN+EREIWDG+RYGPD AR FGFD A+ ++ L+ E+P+L+A+APA+F Sbjct: 65 GAKNQAILFCREKNMEREIWDGFRYGPDVARSTFGFDAAYPIEALDTELPKLMANAPALF 124 Query: 129 YALGRDVKRDAQLQEWLQSVRALGRSGITAPSSIVDVNVLLDEMRLFKDAGEIAVMKRAG 188 YALG D K D Q+Q WLQSVRA R+G+T P++ D++VLLDEMRL KDA EIA+M+R+ Sbjct: 125 YALGSDSKLDTQVQGWLQSVRAQARAGVTPPNAAYDIHVLLDEMRLIKDANEIAIMQRSA 184 Query: 189 LISAEAHCRAMRLSRPGLREYHLEAELLHEFRNNGSQYPAYGSIVATGANACVLHYRAGD 248 I+A AH RAMR+SRPGLREYHLEAE+LHEFRNNGSQ+PAYGSIVATGANACVLHYRA D Sbjct: 185 DIAAAAHRRAMRISRPGLREYHLEAEILHEFRNNGSQFPAYGSIVATGANACVLHYRASD 244 Query: 249 AELRDGDLVLIDAGCELDSYASDITRTFPANGKFSGPQKELYEIVLAAQDAAIADTRPGK 308 AEL+DGDLVLIDAGCELDSYASDITRTFPANGKFSGPQKELYEIVLA+QDAA A+TRPGK Sbjct: 245 AELKDGDLVLIDAGCELDSYASDITRTFPANGKFSGPQKELYEIVLASQDAAFAETRPGK 304 Query: 309 RFMDGHDAAVRVLAQGMLDTGLLDKNKVGSLDDVIAKGDYRQFYMHRTGHWLGMDVHDVG 368 RFMDGHDAAV+VLAQGMLDTGLLD+NKVGSLDDVIA Y QFYMHRTGHWLGMDVHDVG Sbjct: 305 RFMDGHDAAVKVLAQGMLDTGLLDRNKVGSLDDVIANRAYSQFYMHRTGHWLGMDVHDVG 364 Query: 369 EYRDPATADGDKPWRTLQPGMVLTVEPGIYVRPGEGVPEKYWNIGIRIEDDAHVTPDGCE 428 EYRD A DKPWRTLQ GMVLTVEPGIYVRP EGVPEKYWNIGIRIEDDA VT G Sbjct: 365 EYRDAAAPGADKPWRTLQEGMVLTVEPGIYVRPAEGVPEKYWNIGIRIEDDALVTATGSH 424 Query: 429 ILTTAVPNKVADIEALMR 446 +L+ A P VADIEALM+ Sbjct: 425 VLSAAAPKTVADIEALMK 442 >A4G250.1 A4G250_HERAR Proline aminopeptidase P II (Xaa-Pro aminopeptidase) (X-Pro aminopeptidase) (Aminopeptidase P II) (APP-II) (Aminoacylproline aminopeptidase) EC=3.4.11.9 Length = 444 Score = 699 bits (1803), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/442 (77%), Positives = 389/442 (88%), Gaps = 2/442 (0%) Query: 5 SFIARRASLIAQMQAKGGGVAIIPTAHEVMRNRDADYPYRHDSYFYYLSGFTEPEAVIVL 64 ++ RRA+L+AQMQAKGGG+AIIPTA EVMRNRDADYPYRHDSYFYYLSGFTEPEAVIVL Sbjct: 3 TYADRRAALMAQMQAKGGGIAIIPTAPEVMRNRDADYPYRHDSYFYYLSGFTEPEAVIVL 62 Query: 65 IAAPGKESRSILFCRDKNLEREIWDGYRYGPDAARQEFGFDEAFAVDTLNKEMPQLLADA 124 IA G+++++ILFCR+KN+EREIWDG+RYGP+ AR FGFD A+ ++ ++ E+P+L+A+A Sbjct: 63 IA--GEKNQAILFCREKNMEREIWDGFRYGPETARSTFGFDAAYPIEAIDTELPRLMANA 120 Query: 125 PAVFYALGRDVKRDAQLQEWLQSVRALGRSGITAPSSIVDVNVLLDEMRLFKDAGEIAVM 184 PA+FYALG D K DAQ+Q WLQ+VRA R+G+T P++ DV+VLLDEMRL KDAGEI +M Sbjct: 121 PALFYALGSDSKLDAQVQRWLQNVRAQARAGVTPPTAAYDVHVLLDEMRLTKDAGEIDIM 180 Query: 185 KRAGLISAEAHCRAMRLSRPGLREYHLEAELLHEFRNNGSQYPAYGSIVATGANACVLHY 244 +R+ I+A AH RAMR++RPGLREYHLEAE+LHEFRNNGSQ+PAYGSIVATGANACVLHY Sbjct: 181 QRSADIAAAAHRRAMRIARPGLREYHLEAEILHEFRNNGSQFPAYGSIVATGANACVLHY 240 Query: 245 RAGDAELRDGDLVLIDAGCELDSYASDITRTFPANGKFSGPQKELYEIVLAAQDAAIADT 304 RA DAEL+DGDLVLIDAGCELDSYASDITR FP NGKFSGPQKELYEIVLA+Q AAIA+T Sbjct: 241 RASDAELKDGDLVLIDAGCELDSYASDITRAFPVNGKFSGPQKELYEIVLASQYAAIAET 300 Query: 305 RPGKRFMDGHDAAVRVLAQGMLDTGLLDKNKVGSLDDVIAKGDYRQFYMHRTGHWLGMDV 364 RPGKRFMDGHDAAV+VLAQGMLDTGLLDKNKVGSL DVI Y QFYMHRTGHWLGMDV Sbjct: 301 RPGKRFMDGHDAAVKVLAQGMLDTGLLDKNKVGSLSDVIEHRAYDQFYMHRTGHWLGMDV 360 Query: 365 HDVGEYRDPATADGDKPWRTLQPGMVLTVEPGIYVRPGEGVPEKYWNIGIRIEDDAHVTP 424 HDVG YRD A +KPWR LQ GMVLTVEPGIYVRP EGVPE+YWNIGIRIEDDA VT Sbjct: 361 HDVGAYRDAAANGAEKPWRMLQAGMVLTVEPGIYVRPAEGVPEQYWNIGIRIEDDAVVTA 420 Query: 425 DGCEILTTAVPNKVADIEALMR 446 DGC IL+ A P VADIEALM+ Sbjct: 421 DGCHILSAAAPKTVADIEALMK 442 >F1VWK4.1 F1VWK4_9BURK Xaa-Pro aminopeptidase Length = 447 Score = 671 bits (1731), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/446 (71%), Positives = 370/446 (82%), Gaps = 5/446 (1%) Query: 6 FIARRASLIAQMQAKGGGVAIIPTAHEVMRNRDADYPYRHDSYFYYLSGFTEPEAVIVLI 65 + ARRASLIAQMQA+GGGVAIIPTA E RN DA+YPYRHDS FYYLSGF EPEAVIVL+ Sbjct: 4 YAARRASLIAQMQARGGGVAIIPTAPEQHRNSDAEYPYRHDSTFYYLSGFAEPEAVIVLV 63 Query: 66 AAPGKESRSILFCRDKNLEREIWDGYRYGPDAARQEFGFDEAFAVDTLNKEMPQLLADAP 125 A GK+++SILFCR+KN EREIW+G+R+GP+ AR+ FGFD AF +D L+ +P+LLAD P Sbjct: 64 A--GKKTQSILFCREKNTEREIWEGFRHGPEGAREAFGFDAAFPIDALDAILPKLLADEP 121 Query: 126 AVFYALGRDVKRDAQLQEWLQSVRALGRSGITAPSSIVDVNVLLDEMRLFKDAGEIAVMK 185 A+FYALG + DAQ++ WL+ VR R+GITAPSS DV+ LL+EMRL KD E+A+M+ Sbjct: 122 ALFYALGSNAALDAQVRGWLKKVRTQSRAGITAPSSAHDVSCLLNEMRLIKDDSELAIMR 181 Query: 186 RAGLISAEAHCRAMRLSRPGLREYHLEAELLHEFRNNGSQYPAYGSIVATGANACVLHYR 245 RA +SAEAH RAMR++RPGL EY ++AELLHEFRN+GS +PAY SIVATGANACVLHYR Sbjct: 182 RAATVSAEAHARAMRMARPGLHEYQIDAELLHEFRNHGSDFPAYTSIVATGANACVLHYR 241 Query: 246 AGDAELRDGDLVLIDAGCELDSYASDITRTFPANGKFSGPQKELYEIVLAAQDAAIADTR 305 AG L+DGDLVLIDAGCELD YASDITRTFPANG F+ Q LY +VLAAQ AAIA+ R Sbjct: 242 AGATVLQDGDLVLIDAGCELDGYASDITRTFPANGTFTPAQATLYALVLAAQHAAIAEIR 301 Query: 306 PGKRFMDGHDAAVRVLAQGMLDTGLLDKNKVGSLDDVIAKGDYRQFYMHRTGHWLGMDVH 365 PGKRFMDGHDAAVR+L+QGML TGLLD NKVG+LDDVI GDYRQFYMHRTGHWLGMDVH Sbjct: 302 PGKRFMDGHDAAVRILSQGMLATGLLDANKVGTLDDVITNGDYRQFYMHRTGHWLGMDVH 361 Query: 366 DVGEYR---DPATADGDKPWRTLQPGMVLTVEPGIYVRPGEGVPEKYWNIGIRIEDDAHV 422 DVGEYR D AT GDKPWR L PGM LTVEPGIYVRP G+PE+YWNIGIRIEDD V Sbjct: 362 DVGEYREVNDTATTGGDKPWRILHPGMTLTVEPGIYVRPAAGIPEQYWNIGIRIEDDIAV 421 Query: 423 TPDGCEILTTAVPNKVADIEALMRSA 448 T G E++++ P +ADIEA+MR+A Sbjct: 422 TASGAEVMSSDAPKTIADIEAMMRNA 447