BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0010.p (351 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6SV55.1 MUTL_JANMA DNA mismatch repair protein mutL 511 e-143 A4G289.1 MUTL_HERAR DNA mismatch repair protein mutL 507 e-141 D8J015.1 D8J015_HERSS DNA mismatch repair protein mutL 487 e-136 F1VX50.1 F1VX50_9BURK DNA mismatch repair protein MutL 484 e-134 E8YN79.1 E8YN79_9BURK DNA mismatch repair protein MutL 398 e-109 >A6SV55.1 MUTL_JANMA DNA mismatch repair protein mutL Length = 613 Score = 511 bits (1315), Expect = e-143, Method: Compositional matrix adjust. Identities = 260/352 (73%), Positives = 288/352 (81%), Gaps = 22/352 (6%) Query: 1 VLHGDRYPSYALSLDLDPALVDVNVHPSKIEVRFRDSRSVHQFVFHAVSRALAATSATSF 60 VLHGDRYPSY +SLDLDPALVDVNVHPSKIEVRFRDSRSVHQFVFHAVSRALA TSAT+F Sbjct: 283 VLHGDRYPSYVISLDLDPALVDVNVHPSKIEVRFRDSRSVHQFVFHAVSRALAQTSATAF 342 Query: 61 GNAPAPQAASNGPLPWMRDQQGQPQPQYQNAFGAQLRPNFSAGNFGVAQNTAEYGAMFQP 120 G P+P A +G LPW+R+QQ Q F Q + + GVAQ TA YGA+F Sbjct: 343 GAVPSPTPAPSGALPWLREQQ-------QTTFAPQFQQQY-----GVAQTTANYGALF-- 388 Query: 121 GVQTNLDMAST-FGSEAAPGAFVMPVSAGAPMQTLPADDFPLGFALAQLHGIYVLAQNSK 179 N D A T G+E AP AF +P QT+ D+FPLGFALAQLHGI++LAQN+K Sbjct: 389 ----NTDGAVTPLGTEPAP-AFA--AFTNSPAQTMSDDEFPLGFALAQLHGIFILAQNTK 441 Query: 180 GLVVVDMHAAHERILYEQLKNALDDNSMFVQPLLIPVTFYADAVEVGTVEEHQETLSALG 239 GLV+VDMHAAHERILYEQLKNALDDN+M VQPLLIP+TFYAD VEVGT E+ +ETL +LG Sbjct: 442 GLVLVDMHAAHERILYEQLKNALDDNAMQVQPLLIPITFYADDVEVGTAEDSKETLLSLG 501 Query: 240 FDIAAMSPTTLAVRAVPALLKNADAQTLARDVLRDVREFGGSRVLLERRNELLGTLACHT 299 FDIA MSPTTLA+RAVP LLKNADAQ+LARDVLRDVRE+GGSRVL+ERRNELLGTLACHT Sbjct: 502 FDIAVMSPTTLAIRAVPTLLKNADAQSLARDVLRDVREYGGSRVLVERRNELLGTLACHT 561 Query: 300 AVRANRSLTVPEMNALLRQMEATERADQCNHGRPTWSQLALSDMDKLFLRGQ 351 AVRANR LT PEMNALLRQMEATERADQCNHGRPTW QL LSD+DKLF RG+ Sbjct: 562 AVRANRMLTGPEMNALLRQMEATERADQCNHGRPTWVQLGLSDLDKLFERGR 613 >A4G289.1 MUTL_HERAR DNA mismatch repair protein mutL Length = 612 Score = 507 bits (1305), Expect = e-141, Method: Compositional matrix adjust. Identities = 257/351 (73%), Positives = 291/351 (82%), Gaps = 21/351 (5%) Query: 1 VLHGDRYPSYALSLDLDPALVDVNVHPSKIEVRFRDSRSVHQFVFHAVSRALAATSATSF 60 VLHGDRYPSY +SL+LDPALVDVNVHPSKIEVRFRDSR+VHQFVFHAV+RALA TSAT+F Sbjct: 283 VLHGDRYPSYVISLELDPALVDVNVHPSKIEVRFRDSRAVHQFVFHAVTRALAQTSATAF 342 Query: 61 GNAPAPQAASNGPLPWMRDQQGQPQPQYQNAFGAQLRPNFSAGNFGVAQNTAEYGAMFQP 120 G AP+P A + LPW+R+QQ Q+ F P F++ +GVAQ+ A YGA+F Sbjct: 343 GAAPSPTPAPSSALPWLREQQ-------QSTFA----PQFNS-PYGVAQSAANYGALFAN 390 Query: 121 GVQTNLDMASTFGSEAAPGAFVMPVSAGAPMQTLPADDFPLGFALAQLHGIYVLAQNSKG 180 G +N S +A + S GA TLP D+FPLGFALAQLHGI++LAQN+KG Sbjct: 391 GPASN-------DSNSAAPSLHTAGSHGA--TTLPDDEFPLGFALAQLHGIFILAQNTKG 441 Query: 181 LVVVDMHAAHERILYEQLKNALDDNSMFVQPLLIPVTFYADAVEVGTVEEHQETLSALGF 240 LV+VDMHAAHERILYEQLK+ALDDN + VQPLLIP+TFYAD +EVGT E++Q+ L ALGF Sbjct: 442 LVLVDMHAAHERILYEQLKHALDDNELQVQPLLIPITFYADGMEVGTTEDNQDILHALGF 501 Query: 241 DIAAMSPTTLAVRAVPALLKNADAQTLARDVLRDVREFGGSRVLLERRNELLGTLACHTA 300 DIAA+SPTTLAVRAVPALLKNADAQTLARDVLRDVREFGGSRVLLERRNELLGTLACHTA Sbjct: 502 DIAALSPTTLAVRAVPALLKNADAQTLARDVLRDVREFGGSRVLLERRNELLGTLACHTA 561 Query: 301 VRANRSLTVPEMNALLRQMEATERADQCNHGRPTWSQLALSDMDKLFLRGQ 351 VRANR+LTVPEMNALLRQMEATERADQCNHGRPTW QL LSD+DKLF RG+ Sbjct: 562 VRANRTLTVPEMNALLRQMEATERADQCNHGRPTWVQLGLSDLDKLFERGR 612 >D8J015.1 D8J015_HERSS DNA mismatch repair protein mutL Length = 627 Score = 487 bits (1254), Expect = e-136, Method: Compositional matrix adjust. Identities = 268/365 (73%), Positives = 285/365 (78%), Gaps = 26/365 (7%) Query: 1 VLHGDRYPSYALSLDLDPALVDVNVHPSKIEVRFRDSRSVHQFVFHAVSRALAATSATSF 60 VLHGDRYP+YALSL LDPALVDVNVHPSKIEVRFRDSR+VHQFVFHAVSRALA TSA SF Sbjct: 275 VLHGDRYPAYALSLTLDPALVDVNVHPSKIEVRFRDSRAVHQFVFHAVSRALAQTSAVSF 334 Query: 61 GNAP--APQAASNGPLP---------WMRDQQGQPQPQYQNAFGAQL-RPNFSAGN--FG 106 GN P APQ+ + P W+ G+ Q Q +A A+ RP GN FG Sbjct: 335 GNLPGAAPQSDDSAGAPPPAANAPLPWI----GEQQQQSFSAQFAEAPRPFSFGGNSGFG 390 Query: 107 VAQNTAEYGAMFQPGVQTNLDMASTFGSEAAPGAFVMPVSAGAPMQTLPADDFPLGFALA 166 V QNT YG+MF+ A T G + A LP DFPLGFALA Sbjct: 391 VRQNTEAYGSMFRS--------APTSGEPDGSAPAAYGATPAAAPAALPEGDFPLGFALA 442 Query: 167 QLHGIYVLAQNSKGLVVVDMHAAHERILYEQLKNALDDNSMFVQPLLIPVTFYADAVEVG 226 QLHGIYVLAQN GLVVVDMHAAHERILYEQLK ALD N MFVQPLLIPVTFYAD VEVG Sbjct: 443 QLHGIYVLAQNQAGLVVVDMHAAHERILYEQLKTALDGNEMFVQPLLIPVTFYADPVEVG 502 Query: 227 TVEEHQETLSALGFDIAAMSPTTLAVRAVPALLKNADAQTLARDVLRDVREFGGSRVLLE 286 TVEEHQETLSALGFDIA MSPTTLAVRAVPALLKNADAQTLARDVLRDVRE+GGSRVLLE Sbjct: 503 TVEEHQETLSALGFDIAVMSPTTLAVRAVPALLKNADAQTLARDVLRDVREYGGSRVLLE 562 Query: 287 RRNELLGTLACHTAVRANRSLTVPEMNALLRQMEATERADQCNHGRPTWSQLALSDMDKL 346 RRNELLGTLACHTAVRANRSLT+PEMNALLRQMEATER+DQCNHGRPTW+Q+ LSD+DKL Sbjct: 563 RRNELLGTLACHTAVRANRSLTLPEMNALLRQMEATERSDQCNHGRPTWTQMGLSDLDKL 622 Query: 347 FLRGQ 351 FLRGQ Sbjct: 623 FLRGQ 627 >F1VX50.1 F1VX50_9BURK DNA mismatch repair protein MutL Length = 612 Score = 484 bits (1245), Expect = e-134, Method: Compositional matrix adjust. Identities = 252/352 (71%), Positives = 281/352 (79%), Gaps = 18/352 (5%) Query: 1 VLHGDRYPSYALSLDLDPALVDVNVHPSKIEVRFRDSRSVHQFVFHAVSRALAATSATSF 60 VLHGDRYPSY L+LDLDPALVDVNVHPSKIEVRFRDSR+VHQFVFHAV+RAL+ TSAT+ Sbjct: 278 VLHGDRYPSYVLALDLDPALVDVNVHPSKIEVRFRDSRAVHQFVFHAVTRALSQTSATAD 337 Query: 61 GNAPAPQAASNGPLPWMRDQQGQPQP-QYQNAFGAQLRPNFSAGNFGVAQNTAEYGAMFQ 119 G PAPQAA G +PW QQ QP Q +F Q P G+AQN+A YGA+F Sbjct: 338 GMVPAPQAA--GAMPWHSTQQTPAQPYTRQGSFSQQAEP-------GIAQNSARYGALFG 388 Query: 120 PGVQTNLDMASTFGSEAAPGAFVMPVSAGAPMQTLPADDFPLGFALAQLHGIYVLAQNSK 179 + + D F A G P A AP T +FPLGFALAQL GIY+LAQN Sbjct: 389 ---EKSGDSNEAFEQVAVAG--WQPSPAVAPSGTA---EFPLGFALAQLQGIYILAQNLT 440 Query: 180 GLVVVDMHAAHERILYEQLKNALDDNSMFVQPLLIPVTFYADAVEVGTVEEHQETLSALG 239 GLV+VDMHAAHERILYEQ K ALD +++ VQPLLIPVTF+ADAVEVGT E+Q TL+ALG Sbjct: 441 GLVLVDMHAAHERILYEQFKTALDTDAVVVQPLLIPVTFHADAVEVGTTAENQATLAALG 500 Query: 240 FDIAAMSPTTLAVRAVPALLKNADAQTLARDVLRDVREFGGSRVLLERRNELLGTLACHT 299 FDIAA+SPTTLAVRA+PALLKNADAQ+LARDVLRDVREFGGSRVL+ERRNELLGTLACHT Sbjct: 501 FDIAALSPTTLAVRAIPALLKNADAQSLARDVLRDVREFGGSRVLMERRNELLGTLACHT 560 Query: 300 AVRANRSLTVPEMNALLRQMEATERADQCNHGRPTWSQLALSDMDKLFLRGQ 351 AVRANR LT+PEMNALLRQMEATERADQCNHGRPTW Q+ALSD+D+LF RGQ Sbjct: 561 AVRANRILTLPEMNALLRQMEATERADQCNHGRPTWVQMALSDLDRLFQRGQ 612 >E8YN79.1 E8YN79_9BURK DNA mismatch repair protein MutL Length = 682 Score = 398 bits (1022), Expect = e-109, Method: Compositional matrix adjust. Identities = 223/392 (56%), Positives = 260/392 (66%), Gaps = 43/392 (10%) Query: 1 VLHGDRYPSYALSLDLDPALVDVNVHPSKIEVRFRDSRSVHQFVFHAVSRALA-----AT 55 VLHGDRYPSY L LDL P VDVNVHPSKIEVRFRDSRS+HQFVFHAV RALA + Sbjct: 293 VLHGDRYPSYVLFLDLPPEAVDVNVHPSKIEVRFRDSRSIHQFVFHAVQRALARHAGASP 352 Query: 56 SATSFGNAPAPQAASNGPLPW-------------------------------MRDQQGQP 84 T+ G+A QA+++G + + G Sbjct: 353 ETTAGGHAAHLQASADGAVSFGASPAASAGFAASGAMNGANAAGGSGANASSGSSGSGFS 412 Query: 85 QPQYQNAFGAQLRPNFSAGNFGVAQNTAEYGAMF--QPGVQTNLDMASTFGSEAAPGAFV 142 Q N + Q R + G VAQ A Y A+F + A+ F + + Sbjct: 413 ASQAGNTWMRQSR--MTQGTLPVAQPLAFYDALFGRKDSSAATAQGATLFEARDSAAEGP 470 Query: 143 MPVSAGAPMQT---LPADDFPLGFALAQLHGIYVLAQNSKGLVVVDMHAAHERILYEQLK 199 P +A AP + PADD PLGFAL Q+HGIYVLAQN+ GLV+VDMHAAHERILYEQ K Sbjct: 471 SPYNASAPHASPAFHPADDQPLGFALGQIHGIYVLAQNAHGLVIVDMHAAHERILYEQFK 530 Query: 200 NALDDNSMFVQPLLIPVTFYADAVEVGTVEEHQETLSALGFDIAAMSPTTLAVRAVPALL 259 NAL D ++ VQPLLIP T AD VE+GTVEE +ETL ALGFD+A +SPTTLA+RAVPALL Sbjct: 531 NALADRTIAVQPLLIPQTLQADPVEIGTVEEERETLDALGFDLAILSPTTLAIRAVPALL 590 Query: 260 KNADAQTLARDVLRDVREFGGSRVLLERRNELLGTLACHTAVRANRSLTVPEMNALLRQM 319 K+AD Q LAR VL D+ +GGSRVL ER++ELLGTLACH AVRANR LT+ EMNALLRQM Sbjct: 591 KDADLQALARAVLSDLHAYGGSRVLTERQHELLGTLACHHAVRANRRLTLDEMNALLRQM 650 Query: 320 EATERADQCNHGRPTWSQLALSDMDKLFLRGQ 351 EATERADQCNHGRPTW QL LSD+D+LF+RGQ Sbjct: 651 EATERADQCNHGRPTWYQLTLSDLDRLFMRGQ 682