BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0009.p (258 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J015.1 D8J015_HERSS DNA mismatch repair protein mutL 387 e-105 A6SV55.1 MUTL_JANMA DNA mismatch repair protein mutL 360 2e-97 A4G289.1 MUTL_HERAR DNA mismatch repair protein mutL 353 1e-95 F1VX50.1 F1VX50_9BURK DNA mismatch repair protein MutL 327 9e-88 B5SH85.1 B5SH85_RALSO DNA mismatch repair protein mutL 302 3e-80 >D8J015.1 D8J015_HERSS DNA mismatch repair protein mutL Length = 627 Score = 387 bits (993), Expect = e-105, Method: Compositional matrix adjust. Identities = 189/204 (92%), Positives = 196/204 (96%) Query: 12 RPIQALPDQLISQIAAGEVIERPSAVVKELLENALDAGATHITVRLEQGGVKRIAITDNG 71 RPIQALPDQLISQIAAGEVIERPSAVVKELLENALDAG+T ITVRLEQGGVKRIAITDNG Sbjct: 5 RPIQALPDQLISQIAAGEVIERPSAVVKELLENALDAGSTQITVRLEQGGVKRIAITDNG 64 Query: 72 RGIPPEQMPLALARHATSKIASLTDLENVGTLGFRGEALASIASVAQLTLTTRTADAAHA 131 RGIPPEQ+PLALARHATSKIASLTDLENV TLGFRGEALASIASVAQLT+T+RTADA HA Sbjct: 65 RGIPPEQLPLALARHATSKIASLTDLENVSTLGFRGEALASIASVAQLTVTSRTADAPHA 124 Query: 132 WEIIGSQEGSVVPASGAPGTTIDVQDLYFNTPARRKFLKSEQTEYGHCAEVVRRIALARP 191 WEI GSQ G+V PASGA GTTIDVQDLYFNTPARRKFLKSEQTEYGHCAEVVRRIALARP Sbjct: 125 WEITGSQFGTVAPASGAQGTTIDVQDLYFNTPARRKFLKSEQTEYGHCAEVVRRIALARP 184 Query: 192 DVTFSLTHNGKTVDHWNTGEFAKR 215 DV+FSL+HNGKTVDHWN GEFAKR Sbjct: 185 DVSFSLSHNGKTVDHWNVGEFAKR 208 >A6SV55.1 MUTL_JANMA DNA mismatch repair protein mutL Length = 613 Score = 360 bits (923), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 176/212 (83%), Positives = 191/212 (90%), Gaps = 4/212 (1%) Query: 8 SRPLRPIQALPDQLISQIAAGEVIERPSAVVKELLENALDAGATHITVRLEQGGVKRIAI 67 ++P RPIQ L DQLISQIAAGEV+ERPSAVVKELLENALDAGAT ITVRLEQGGVKRIAI Sbjct: 5 TQPFRPIQPLSDQLISQIAAGEVVERPSAVVKELLENALDAGATAITVRLEQGGVKRIAI 64 Query: 68 TDNGRGIPPEQMPLALARHATSKIASLTDLENVGTLGFRGEALASIASVAQLTLTTRTAD 127 TDNGRGI PEQ+PLALARHATSKI SL +LENVGTLGFRGEALASIASVAQLTLT+RTAD Sbjct: 65 TDNGRGITPEQLPLALARHATSKINSLNELENVGTLGFRGEALASIASVAQLTLTSRTAD 124 Query: 128 AAHAWEIIG----SQEGSVVPASGAPGTTIDVQDLYFNTPARRKFLKSEQTEYGHCAEVV 183 A HAWEI G Q+ +V P+SGAPGTT+DVQDLYFNTPARRKFLK+EQTE+GHCAEVV Sbjct: 125 AQHAWEISGVQGSDQKNTVAPSSGAPGTTVDVQDLYFNTPARRKFLKTEQTEFGHCAEVV 184 Query: 184 RRIALARPDVTFSLTHNGKTVDHWNTGEFAKR 215 RRIAL+RPDV FSL+HNGKTVDHW + AKR Sbjct: 185 RRIALSRPDVAFSLSHNGKTVDHWAVNDIAKR 216 >A4G289.1 MUTL_HERAR DNA mismatch repair protein mutL Length = 612 Score = 353 bits (906), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 172/209 (82%), Positives = 189/209 (90%), Gaps = 4/209 (1%) Query: 11 LRPIQALPDQLISQIAAGEVIERPSAVVKELLENALDAGATHITVRLEQGGVKRIAITDN 70 +RPIQAL DQLISQIAAGEV+ERPSAVVKELLENALDAGATHI+VRLEQGGVKRIAITDN Sbjct: 8 VRPIQALSDQLISQIAAGEVVERPSAVVKELLENALDAGATHISVRLEQGGVKRIAITDN 67 Query: 71 GRGIPPEQMPLALARHATSKIASLTDLENVGTLGFRGEALASIASVAQLTLTTRTADAAH 130 GRGI PEQ+PLALARHATSKI SLT+LENV TLGFRGEALASIASV+QLTLT+RTADAAH Sbjct: 68 GRGIAPEQLPLALARHATSKINSLTELENVATLGFRGEALASIASVSQLTLTSRTADAAH 127 Query: 131 AWEIIG----SQEGSVVPASGAPGTTIDVQDLYFNTPARRKFLKSEQTEYGHCAEVVRRI 186 AWEI G Q+ +V P+SG GTT+DV DLYFNTPARRKFLK+EQTE+GHCAEVVRRI Sbjct: 128 AWEISGVQSIDQKSTVAPSSGTAGTTVDVLDLYFNTPARRKFLKTEQTEFGHCAEVVRRI 187 Query: 187 ALARPDVTFSLTHNGKTVDHWNTGEFAKR 215 AL+RPDV FSLTHNGKT+DHW + A+R Sbjct: 188 ALSRPDVAFSLTHNGKTIDHWAVNDIARR 216 >F1VX50.1 F1VX50_9BURK DNA mismatch repair protein MutL Length = 612 Score = 327 bits (838), Expect = 9e-88, Method: Compositional matrix adjust. Identities = 172/204 (84%), Positives = 187/204 (91%), Gaps = 1/204 (0%) Query: 12 RPIQALPDQLISQIAAGEVIERPSAVVKELLENALDAGATHITVRLEQGGVKRIAITDNG 71 R I ALPDQLISQIAAGEV+ERPSAVVKELLENALDAGAT IT+RLEQGG+KRIAITDNG Sbjct: 9 RSIAALPDQLISQIAAGEVVERPSAVVKELLENALDAGATQITIRLEQGGIKRIAITDNG 68 Query: 72 RGIPPEQMPLALARHATSKIASLTDLENVGTLGFRGEALASIASVAQLTLTTRTADAAHA 131 RGIP +++PLALARHATSKIASL+DLENV TLGFRGEALASIAS+AQLTLTTRTA AAHA Sbjct: 69 RGIPADEIPLALARHATSKIASLSDLENVATLGFRGEALASIASIAQLTLTTRTATAAHA 128 Query: 132 WEIIGSQEGSVVPASGAPGTTIDVQDLYFNTPARRKFLKSEQTEYGHCAEVVRRIALARP 191 WE+ GSQ VP+SGAPGTTIDVQDLY+NTPARRKFLKS+QTEYGHCAEVVRRIAL+RP Sbjct: 129 WEMSGSQPAP-VPSSGAPGTTIDVQDLYYNTPARRKFLKSDQTEYGHCAEVVRRIALSRP 187 Query: 192 DVTFSLTHNGKTVDHWNTGEFAKR 215 DV FSLTHNGKTVDHW + +R Sbjct: 188 DVAFSLTHNGKTVDHWTLADMDRR 211 >B5SH85.1 B5SH85_RALSO DNA mismatch repair protein mutL Length = 647 Score = 302 bits (774), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 147/200 (73%), Positives = 174/200 (87%), Gaps = 1/200 (0%) Query: 12 RPIQALPDQLISQIAAGEVIERPSAVVKELLENALDAGATHITVRLEQGGVKRIAITDNG 71 RPI+ LPDQLISQIAAGEV+ERP++VVKELLENALDAGAT + ++LE+GGV+RIAITDNG Sbjct: 13 RPIRPLPDQLISQIAAGEVVERPASVVKELLENALDAGATQLQIKLEEGGVRRIAITDNG 72 Query: 72 RGIPPEQMPLALARHATSKIASLTDLENVGTLGFRGEALASIASVAQLTLTTRTADAAHA 131 GIP +++P+AL RHATSKI SL +LE+V TLGFRGEALASIASVA+LTLT+RTADAAHA Sbjct: 73 GGIPVDELPVALMRHATSKIGSLEELESVATLGFRGEALASIASVAELTLTSRTADAAHA 132 Query: 132 WEIIGSQEGSVVPASGAPGTTIDVQDLYFNTPARRKFLKSEQTEYGHCAEVVRRIALARP 191 +I+ +Q G + PASG GTT+DVQ LYFNTPARRKFLKSEQTE GHC EV+RR ALARP Sbjct: 133 TQIL-AQSGRLQPASGGVGTTVDVQHLYFNTPARRKFLKSEQTELGHCLEVIRRTALARP 191 Query: 192 DVTFSLTHNGKTVDHWNTGE 211 DV S+ HNGK ++HWN + Sbjct: 192 DVAISVHHNGKPLEHWNAAQ 211