BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0033.p (354 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IV65.1 D8IV65_HERSS Short chain dehydrogenase/reductase protein 423 e-116 E8YWB9.1 E8YWB9_9BURK Short-chain dehydrogenase/reductase SDR 347 2e-93 B1G870.1 B1G870_9BURK Short-chain dehydrogenase/reductase SDR 346 3e-93 E1THA9.1 E1THA9_BURSG Short-chain dehydrogenase/reductase SDR 340 2e-91 A1K6A1.1 A1K6A1_AZOSB Short-chain dehydrogenase family protein 332 5e-89 >D8IV65.1 D8IV65_HERSS Short chain dehydrogenase/reductase protein Length = 339 Score = 423 bits (1088), Expect = e-116, Method: Compositional matrix adjust. Identities = 222/332 (66%), Positives = 270/332 (81%), Gaps = 3/332 (0%) Query: 18 MRIQLKKISDQTIVITGATSGIGLVTARLAASRGANLLLIARNEDALDRIAKELDPAGKK 77 M I+LK I+DQTIVITGA+SGIGL TARLAA+R A L+L+AR+ AL+R+A ELDP+G++ Sbjct: 1 MTIRLKPIADQTIVITGASSGIGLATARLAAARQARLVLVARDAQALERVAAELDPSGRR 60 Query: 78 TIWAVADVADRSALEEAAAKAITQFGQIDTWINNAGVSIYGRNTEVSLEDQRRLFDTNYW 137 + ADVAD AL+ AA+A+ +FG IDTWINNAG+SI+GR+ EVSLED RRLF+TNYW Sbjct: 61 VMHLAADVADLVALQAVAAQAVERFGGIDTWINNAGISIFGRHEEVSLEDHRRLFETNYW 120 Query: 138 GVVNGSLVAVEHLRQ--AGGAIINLGSELSDVAVPLQGAYSASKHAVKGFTDSLRVELAE 195 GVVNGSL A+ HL+ G +INLGSELSDVAVPLQGAYSASKHAVKGFTDSLRVELAE Sbjct: 121 GVVNGSLAALPHLKANPEGAVLINLGSELSDVAVPLQGAYSASKHAVKGFTDSLRVELAE 180 Query: 196 ENVPISVTLIKPAGVDTQFVLHAKNYMEVEPKLPPPVYAPAIAAEAILTAAQQPRRDIYV 255 + +SVTL+KPA +DT F HAKNYM+V+PKLPPPVYAPAIAAEAIL AA RRDIYV Sbjct: 181 QGARVSVTLVKPAAIDTPFTRHAKNYMDVQPKLPPPVYAPAIAAEAILVAACAVRRDIYV 240 Query: 256 GAASKLISSTNKCVPALLDVYLKNCMFSQQRTETPKTDDGNALHAPLANASIRERGGATK 315 GAAS+L SS NKC PAL+D YL++CMF+QQR++ P++ + + LHA A ++ ERGG Sbjct: 241 GAASRLFSSANKCAPALVDQYLQSCMFAQQRSDQPRSSEPDHLHASAARGALAERGGERY 300 Query: 316 VMPLSPYTFATSRAPVASRLAFLG-IAFVLGR 346 VMP SPYT+A+SRAP+ +RLA LG + LGR Sbjct: 301 VMPCSPYTWASSRAPMLTRLALLGTVCLALGR 332 >E8YWB9.1 E8YWB9_9BURK Short-chain dehydrogenase/reductase SDR Length = 338 Score = 347 bits (890), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 176/311 (56%), Positives = 231/311 (74%), Gaps = 6/311 (1%) Query: 18 MRIQLKKISDQTIVITGATSGIGLVTARLAASRGANLLLIARNEDALDRIAKELDPAGKK 77 M ++LK I+ Q +VITGATSGIGL TARLAASRGA L+LIAR+E+AL+ +A +L G Sbjct: 1 MTVKLKPIAQQVVVITGATSGIGLATARLAASRGARLMLIARDEEALETLATQLRDQGAL 60 Query: 78 TIWAVADVADRSALEEAAAKAITQFGQIDTWINNAGVSIYGRNTEVSLEDQRRLFDTNYW 137 +AVADV + + LE AA +AI +FG DTW+NNAG SI+GR +V +++Q+ LF+TN+W Sbjct: 61 VEYAVADVGNAAQLEAAADQAIARFGGFDTWVNNAGASIFGRCADVPIDEQKALFETNFW 120 Query: 138 GVVNGSLVAVEHLRQAGGAIINLGSELSDVAVPLQGAYSASKHAVKGFTDSLRVELAEEN 197 GVV GS++A+ HL Q GGA+INLGSELSD+A+PLQ AY ASKHAVKG+TD+LR+EL EE Sbjct: 121 GVVQGSMIALAHLTQQGGALINLGSELSDIALPLQAAYVASKHAVKGYTDALRMELIEER 180 Query: 198 VPISVTLIKPAGVDTQFVLHAKNYMEVEPKLPPPVYAPAIAAEAILTAAQQPRRDIYVGA 257 P+SVTLIKP+G+ TQFV HA+N+++V+PKLPPPVYAP I A+AIL AA P RD+YVG Sbjct: 181 APVSVTLIKPSGIHTQFVEHARNHLDVQPKLPPPVYAPDIVAKAILHAASTPVRDLYVGG 240 Query: 258 ASKLISSTNKCVPALLDVYLKNCMFSQQRT-ETPKTDDGNALHAPLANASIRERGGAT-K 315 AS + + + P+L D + S QRT E P+T GN P A+ ++RER G + Sbjct: 241 ASAAMVTFARRAPSLYDRVMSRFGISSQRTNEPPRTPAGN----PGADGALRERSGQKRR 296 Query: 316 VMPLSPYTFAT 326 V+ S YT A+ Sbjct: 297 VLESSLYTQAS 307 >B1G870.1 B1G870_9BURK Short-chain dehydrogenase/reductase SDR Length = 338 Score = 346 bits (888), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 176/311 (56%), Positives = 232/311 (74%), Gaps = 6/311 (1%) Query: 18 MRIQLKKISDQTIVITGATSGIGLVTARLAASRGANLLLIARNEDALDRIAKELDPAGKK 77 M ++LK +S Q IVITGATSGIGL TARLAASRGA L+LIAR+E+AL +A +L G Sbjct: 1 MTVKLKPVSQQVIVITGATSGIGLATARLAASRGARLMLIARDEEALRTLATQLGDQGAL 60 Query: 78 TIWAVADVADRSALEEAAAKAITQFGQIDTWINNAGVSIYGRNTEVSLEDQRRLFDTNYW 137 +AVADV++++ L+ AA KAI +FG DTW+NNAG SI+GR +V +++Q+ LF+TN+W Sbjct: 61 VEYAVADVSNQAQLQAAADKAIARFGGFDTWVNNAGGSIFGRCADVPIDEQKELFETNFW 120 Query: 138 GVVNGSLVAVEHLRQAGGAIINLGSELSDVAVPLQGAYSASKHAVKGFTDSLRVELAEEN 197 GVV GS++A+ HL+Q GGA+INLGSELSD+A+PLQ AY ASKHAVKG+TD+LR+EL EE Sbjct: 121 GVVQGSMIALAHLKQRGGALINLGSELSDIALPLQAAYVASKHAVKGYTDTLRMELIEER 180 Query: 198 VPISVTLIKPAGVDTQFVLHAKNYMEVEPKLPPPVYAPAIAAEAILTAAQQPRRDIYVGA 257 P+SVTLIKP+G+ TQFV HA+N+++V+PKLPPPVYAP I A+AIL AA P RD+YVG Sbjct: 181 APVSVTLIKPSGIHTQFVEHARNHLDVQPKLPPPVYAPDIVAKAILHAACTPVRDLYVGG 240 Query: 258 ASKLISSTNKCVPALLDVYLKNCMFSQQRT-ETPKTDDGNALHAPLANASIRERGGAT-K 315 AS + + + P L D + + QRT E P+T DGN H + ++RER G + Sbjct: 241 ASAAMVTFARRAPNLYDRVMSRIGIASQRTQEPPRTPDGN--HGD--DGALRERSGQKRR 296 Query: 316 VMPLSPYTFAT 326 V+ S YT A+ Sbjct: 297 VLESSLYTQAS 307 >E1THA9.1 E1THA9_BURSG Short-chain dehydrogenase/reductase SDR Length = 338 Score = 340 bits (871), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 172/311 (55%), Positives = 229/311 (73%), Gaps = 6/311 (1%) Query: 18 MRIQLKKISDQTIVITGATSGIGLVTARLAASRGANLLLIARNEDALDRIAKELDPAGKK 77 M ++LK ++ Q IVITGATSGIGL TARLAASRGA L+L+AR+E+AL +A +L G Sbjct: 1 MTVKLKPVAQQVIVITGATSGIGLATARLAASRGARLMLVARDEEALRTLATQLADQGAL 60 Query: 78 TIWAVADVADRSALEEAAAKAITQFGQIDTWINNAGVSIYGRNTEVSLEDQRRLFDTNYW 137 +AVADV + L+ AA KAI +FG DTW+NNAG SI+GR +V +++Q+ LF+TN+W Sbjct: 61 VEYAVADVGNADQLQAAADKAIARFGGFDTWVNNAGASIFGRCADVPIDEQKALFETNFW 120 Query: 138 GVVNGSLVAVEHLRQAGGAIINLGSELSDVAVPLQGAYSASKHAVKGFTDSLRVELAEEN 197 GVV GS++A+ HL+Q GGA++NLGSELSDVA+PLQ AY ASKHAVKG+TD+LR+EL EE Sbjct: 121 GVVQGSMIALAHLKQRGGALVNLGSELSDVALPLQAAYVASKHAVKGYTDALRMELIEER 180 Query: 198 VPISVTLIKPAGVDTQFVLHAKNYMEVEPKLPPPVYAPAIAAEAILTAAQQPRRDIYVGA 257 P+SVTLIKP+G+ TQFV HA+N+++V+PKLPPP+YAP I A+AIL AA P RD+YVG Sbjct: 181 APVSVTLIKPSGIHTQFVEHARNHLDVQPKLPPPLYAPDIVAKAILHAACTPVRDLYVGG 240 Query: 258 ASKLISSTNKCVPALLDVYLKNCMFSQQRT-ETPKTDDGNALHAPLANASIRERGGAT-K 315 AS + + + P L D + + QRT E P+T +GN A+ ++RER G + Sbjct: 241 ASAAMVTFARRAPNLYDRVMSRFGIASQRTDEPPRTPEGNQ----GADGALRERSGQKRR 296 Query: 316 VMPLSPYTFAT 326 V+ S YT A+ Sbjct: 297 VLESSLYTQAS 307 >A1K6A1.1 A1K6A1_AZOSB Short-chain dehydrogenase family protein Length = 314 Score = 332 bits (851), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 166/312 (53%), Positives = 222/312 (71%), Gaps = 4/312 (1%) Query: 18 MRIQLKKISDQTIVITGATSGIGLVTARLAASRGANLLLIARNEDALDRIAKELDPAGKK 77 MR+ LK +SDQTIV+TGATSGIGL T R+A ++GA +++ ARN AL +A+ G+ Sbjct: 1 MRLHLKPVSDQTIVVTGATSGIGLATVRMAVAQGARVVMAARNAQALATLAEGFHHLGRS 60 Query: 78 TIWAVADVADRSALEEAAAKAITQFGQIDTWINNAGVSIYGRNTEVSLEDQRRLFDTNYW 137 + ADVA+ ++ A+ FG DTW+NNAGVSI+GR +V L+D RRLF+TN+W Sbjct: 61 AVAVPADVANVQDVQRIRDAALEAFGGFDTWVNNAGVSIFGRYEDVPLQDMRRLFETNFW 120 Query: 138 GVVNGSLVAVEHLRQAGGAIINLGSELSDVAVPLQGAYSASKHAVKGFTDSLRVELAEEN 197 GVV+GS++A+E LR+ GGA+INLGSE+SD+A+PLQG YSASKHAVKGFTDSLR+E+ Sbjct: 121 GVVHGSMIALEILRERGGALINLGSEVSDIALPLQGMYSASKHAVKGFTDSLRMEVEAAG 180 Query: 198 VPISVTLIKPAGVDTQFVLHAKNYMEVEPKLPPPVYAPAIAAEAILTAAQQPRRDIYVGA 257 P+SVTLIKPA +DT FV HA NYM+V+P+LP P+YAP + A+AIL AA QP+RDIYVG Sbjct: 181 YPVSVTLIKPAAIDTPFVPHAANYMDVQPRLPSPLYAPEVVADAILYAAHQPKRDIYVGG 240 Query: 258 ASKLISSTNKCVPALLDVYLKNCMFSQQRTETPKTDDGNA-LHAPLANASIRE-RGGATK 315 A+K S++N+ +P ++D + M QQR+E P A L+ P +RE RG + Sbjct: 241 AAKAFSASNRMMPRVMDKVSERFMIDQQRSERPVAHPTQATLYHP--GGGLREMRGDSRP 298 Query: 316 VMPLSPYTFATS 327 V S YT T+ Sbjct: 299 VHHRSLYTRLTT 310