BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0186.p (365 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value E6V2E6.1 E6V2E6_VARPD Alcohol dehydrogenase zinc-binding domain ... 611 e-173 C5CYA0.1 C5CYA0_VARPS Alcohol dehydrogenase GroES domain protein 601 e-170 Q2SVU6.1 Q2SVU6_BURTA Oxidoreductase, zinc-binding dehydrogenase... 592 e-167 B2JDR9.1 B2JDR9_BURP8 Alcohol dehydrogenase GroES domain protein 587 e-166 D5WCE0.1 D5WCE0_BURSC Alcohol dehydrogenase GroES domain protein 584 e-165 >E6V2E6.1 E6V2E6_VARPD Alcohol dehydrogenase zinc-binding domain protein Length = 376 Score = 611 bits (1575), Expect = e-173, Method: Compositional matrix adjust. Identities = 290/353 (82%), Positives = 316/353 (89%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M+AVVCHGPKDYRL+T+ P GRNEL+I I ACGICASDCKCHSGA MFWGGDGQ SWV Sbjct: 20 MQAVVCHGPKDYRLETVAMPTIGRNELLISIAACGICASDCKCHSGAKMFWGGDGQPSWV 79 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFGYV LGEGAAEHFGV++GDRVIAEQIVPC C FC +GKYWMCEVHNI Sbjct: 80 KAPVIPGHEFFGYVEALGEGAAEHFGVEKGDRVIAEQIVPCGKCRFCTSGKYWMCEVHNI 139 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQR VADGGMA+YMRLP + VHKIP + LEDAAIIEPLSCAIHTVNRGDIQLDDVV Sbjct: 140 FGFQRIVADGGMADYMRLPPTSRVHKIPDGISLEDAAIIEPLSCAIHTVNRGDIQLDDVV 199 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMM Q A+LKTP+KL+V+DLVPERLALA+EFGADV I+P E+A A++KGL Sbjct: 200 VIAGAGPLGLMMVQAARLKTPKKLIVIDLVPERLALAKEFGADVTINPKTENADAIVKGL 259 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 T GYGCDVYIETTG P GVTQGL++IR+LGRFVEFSVFG ETSADWSIIGDRKELDVRGA Sbjct: 260 TEGYGCDVYIETTGAPIGVTQGLEMIRKLGRFVEFSVFGSETSADWSIIGDRKELDVRGA 319 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYP+AIDLLARGLVTSKGIVTH FPL +WE AFALANS+ SIKVLLKP Sbjct: 320 HLGPYCYPIAIDLLARGLVTSKGIVTHDFPLTEWERAFALANSLDSIKVLLKP 372 >C5CYA0.1 C5CYA0_VARPS Alcohol dehydrogenase GroES domain protein Length = 379 Score = 601 bits (1549), Expect = e-170, Method: Compositional matrix adjust. Identities = 286/353 (81%), Positives = 312/353 (88%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M+AVVCHGPKDYRL+T+ P G NEL+I I ACGICASDCKCHSGA MFWGGDGQ SWV Sbjct: 20 MQAVVCHGPKDYRLETVAMPGIGPNELLISIAACGICASDCKCHSGAKMFWGGDGQPSWV 79 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFGYV LGEGAAEHFGV++GDRVIAEQIVPC C FC +GKYWMCEVHNI Sbjct: 80 KAPVIPGHEFFGYVEALGEGAAEHFGVEKGDRVIAEQIVPCGKCRFCTSGKYWMCEVHNI 139 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQR VADGGMA+YMRLP + VH+IP + LEDAAIIEPLSCAIHTVNRGDIQLDDVV Sbjct: 140 FGFQRIVADGGMADYMRLPPTSRVHRIPDGISLEDAAIIEPLSCAIHTVNRGDIQLDDVV 199 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMM Q A LKTP+KL+V+DLVPERLALA++FGADV ID E+A A++KGL Sbjct: 200 VIAGAGPLGLMMVQAAHLKTPKKLIVIDLVPERLALAKKFGADVTIDARTENADAIVKGL 259 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 T GYGCDVYIETTG P GVTQGL++IR+LGRFVEFSVFG ETSADWSIIGDRKELDVRGA Sbjct: 260 TEGYGCDVYIETTGAPIGVTQGLEMIRKLGRFVEFSVFGSETSADWSIIGDRKELDVRGA 319 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYP+AIDLLARGLVTSKGIVTH FPL +WE AF LANS+ SIKVLLKP Sbjct: 320 HLGPYCYPIAIDLLARGLVTSKGIVTHDFPLTEWERAFTLANSLDSIKVLLKP 372 >Q2SVU6.1 Q2SVU6_BURTA Oxidoreductase, zinc-binding dehydrogenase family Length = 363 Score = 592 bits (1527), Expect = e-167, Method: Compositional matrix adjust. Identities = 283/353 (80%), Positives = 315/353 (89%), Gaps = 2/353 (0%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M A+VCH P+DYR++ + P+A ELVIRIGACGICASDCKCHSGA MFWGG WV Sbjct: 11 MTAIVCHAPEDYRVERVAKPRANARELVIRIGACGICASDCKCHSGAKMFWGG--PSPWV 68 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFG+V ELGEGAAEHFGV GDRVIAEQIVPC C +CK+G+YWMCEVHNI Sbjct: 69 KAPVIPGHEFFGHVEELGEGAAEHFGVALGDRVIAEQIVPCGNCRYCKSGQYWMCEVHNI 128 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQREVADGGMAEYMR+PS A+VH+IP+ + LEDAAIIEPL+CAIHTVNRGDIQLDDVV Sbjct: 129 FGFQREVADGGMAEYMRIPSTAIVHRIPLGISLEDAAIIEPLACAIHTVNRGDIQLDDVV 188 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMMTQVAKLKTP++LVV+D V ERLALARE+GADV IDP REDALA++ L Sbjct: 189 VIAGAGPLGLMMTQVAKLKTPKRLVVIDPVGERLALAREYGADVTIDPTREDALAIVHEL 248 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 TGGYGCDVYIETTGVPAGVTQG+ LIR+LGRFVEFSVFGK+T+ DWSIIGDRKELDVRGA Sbjct: 249 TGGYGCDVYIETTGVPAGVTQGMSLIRKLGRFVEFSVFGKDTALDWSIIGDRKELDVRGA 308 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYPVAIDLLARGLVTSKGIVTH F LE+W+EA +ANS+ SIKVL+KP Sbjct: 309 HLGPYCYPVAIDLLARGLVTSKGIVTHGFSLEEWDEAIRVANSLGSIKVLMKP 361 >B2JDR9.1 B2JDR9_BURP8 Alcohol dehydrogenase GroES domain protein Length = 362 Score = 587 bits (1513), Expect = e-166, Method: Compositional matrix adjust. Identities = 281/360 (78%), Positives = 313/360 (86%), Gaps = 2/360 (0%) Query: 2 QYSAVDMKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGD 61 Q ++ M A+VCH PKDYR++ + PQA +ELVIRI ACGICASDCKCHSGA MFWGG Sbjct: 4 QDNSKSMTAIVCHAPKDYRVERVTKPQARAHELVIRIAACGICASDCKCHSGAKMFWGG- 62 Query: 62 GQDSWVKPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWM 121 WVK PV+ GHEFFGYV ELGEGAAEHF V++GDRVIAEQIVPC C +C++G+YWM Sbjct: 63 -PSPWVKAPVIPGHEFFGYVEELGEGAAEHFDVKKGDRVIAEQIVPCGKCRYCRSGQYWM 121 Query: 122 CEVHNIFGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDI 181 CEVHNIFGFQREVADGGMAEYMR+P A+VHKIP + LEDAAIIEPL+CAIHTVNRGDI Sbjct: 122 CEVHNIFGFQREVADGGMAEYMRIPPTAIVHKIPDGISLEDAAIIEPLACAIHTVNRGDI 181 Query: 182 QLDDVVVIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDAL 241 QLDDVVVIAGAGPLGLMMTQVA LKTP+KLVV+DLV ERL LARE+GADV I+P +DAL Sbjct: 182 QLDDVVVIAGAGPLGLMMTQVAHLKTPKKLVVIDLVDERLELAREYGADVTINPKNDDAL 241 Query: 242 AVIKGLTGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKE 301 A++K LT YGCDVYIETTGVPAGV QG+ LIR+LGRFVEFSVFG ET+ DWSIIGDRKE Sbjct: 242 AIVKSLTDNYGCDVYIETTGVPAGVNQGMDLIRKLGRFVEFSVFGAETTMDWSIIGDRKE 301 Query: 302 LDVRGAHLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKPA 361 LDVRGAHLGPYCYPVAIDLLARGLVTSKGIVTH F LE+W+EA +ANS+ SIKVLLKPA Sbjct: 302 LDVRGAHLGPYCYPVAIDLLARGLVTSKGIVTHGFSLEEWDEAIKVANSLDSIKVLLKPA 361 >D5WCE0.1 D5WCE0_BURSC Alcohol dehydrogenase GroES domain protein Length = 362 Score = 584 bits (1506), Expect = e-165, Method: Compositional matrix adjust. Identities = 276/359 (76%), Positives = 314/359 (87%), Gaps = 2/359 (0%) Query: 2 QYSAVDMKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGD 61 Q +M A+VCH PKDYR++ ++ P+A +ELVIRI ACGICASDCKCHSGA MFWGG Sbjct: 4 QSDQQNMTAIVCHAPKDYRVEQVQKPRARAHELVIRIAACGICASDCKCHSGAKMFWGG- 62 Query: 62 GQDSWVKPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWM 121 WVK PV+ GHEFFGYV ELGEGAAEHFGVQ+G+RVIAEQIVPC C +CK+G+YWM Sbjct: 63 -PSPWVKAPVIPGHEFFGYVEELGEGAAEHFGVQKGERVIAEQIVPCGKCRYCKSGQYWM 121 Query: 122 CEVHNIFGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDI 181 CEVHNIFGFQREVADGGMAEYMR+P A+VHKIP + LEDAAIIEPL+CAIHTVNRGD+ Sbjct: 122 CEVHNIFGFQREVADGGMAEYMRIPPTAIVHKIPDGISLEDAAIIEPLACAIHTVNRGDL 181 Query: 182 QLDDVVVIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDAL 241 QLDDVVVIAGAGPLGLMMTQVA LKTP+KLVV+DLV ERLALARE+GADV I+P ++DAL Sbjct: 182 QLDDVVVIAGAGPLGLMMTQVAHLKTPKKLVVIDLVEERLALAREYGADVTINPQKDDAL 241 Query: 242 AVIKGLTGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKE 301 A+I+ LT GYGCDVYIETTG P GV QG+ LIR+LGRFVEFSVFG +T+ DWS+IGDRKE Sbjct: 242 AIIRSLTDGYGCDVYIETTGAPIGVNQGMDLIRKLGRFVEFSVFGADTTLDWSVIGDRKE 301 Query: 302 LDVRGAHLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 LDVRGAHLGPYCYP+AIDLLARGLVTSKGIVTH F LE+W+EA +ANS+ SIKVL+KP Sbjct: 302 LDVRGAHLGPYCYPIAIDLLARGLVTSKGIVTHGFSLEEWDEAIRIANSLDSIKVLMKP 360