BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0062.p (693 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C5CZH7.1 C5CZH7_VARPS Diguanylate cyclase 353 7e-95 D8IUA8.1 D8IUA8_HERSS ATP-dependent DNA ligase protein EC=6.5.1.1 330 4e-88 A4G5V3.1 A4G5V3_HERAR Putative uncharacterized protein 302 1e-79 A8GGC9.1 A8GGC9_SERP5 Diguanylate cyclase 300 8e-79 C6XB41.1 C6XB41_METSD DNA ligase D 299 1e-78 >C5CZH7.1 C5CZH7_VARPS Diguanylate cyclase Length = 512 Score = 353 bits (905), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 170/353 (48%), Positives = 245/353 (69%), Gaps = 1/353 (0%) Query: 37 FVGLVCLSILILHISFAWNVRVKDLDDAQISTANLSRALAEHAQATLISADSVLFGMVQR 96 FV +VCLS+L + +W R L ++T+NLSRA+A+ A T+ AD+VL GMV+R Sbjct: 14 FVAVVCLSLLAIDFWNSWEARTDQLQQMNVATSNLSRAMAQQADDTIKKADTVLVGMVER 73 Query: 97 LEVEGMDRDSLARLYPLLASYVKELPQIQGLFVYDQSGKWMVNSMDDSPWMLNNADREYF 156 +E +G D +ARL LLA V ELPQ+ GL +YDQ G W+ NS P LNNADREYF Sbjct: 74 VEHDGTDPSDVARLRQLLALRVAELPQLDGLHIYDQDGNWIANSRPTRPENLNNADREYF 133 Query: 157 IYHMTHEDRNPHVGEPVKSRSSGDWIIPLSRRINHPDGSFAGVVLASVEVEYFLKFYRSF 216 +H TH +R PH+G PV+SR+SG ++P+SRRINH DGSFAGV LA++ V++F +FY S Sbjct: 134 AFHRTHAERGPHIGIPVQSRTSGRLLVPVSRRINHADGSFAGVALATIHVDFFSRFYDSL 193 Query: 217 DIGKHGEILLATQPGILLAKWPASGEIIGKNISNSNIVSDHASRNRNGIAIITGA-DGVK 275 DIG+ G + L + G ++ + P S +++G+N+ + + +A+ G A I A DGV Sbjct: 194 DIGQAGAVALVLENGTMMTRRPYSPDMVGRNMLETQLFRSYAAHGPVGTAYIKSAQDGVT 253 Query: 276 RLHSYKRLEKYPLFVTAALSYDEVLASWRTETLMQSVGVLILVAMLAWMGKRLINQIKLR 335 RL+S++RL+ YPLFV+AALS DE+LA+W +TL S GV++L ++ ++G RL+ Q +L+ Sbjct: 254 RLNSFRRLDNYPLFVSAALSKDEILANWWRDTLWHSGGVVLLSLIVGFIGWRLVRQFQLQ 313 Query: 336 AQAQQKLLSAREKLVEMNKTLQKMALEDGLTGVANRRQFDVTLANEFNRAKRD 388 + + +L AR+ L +NKTL +A+EDGLTG+ANRRQFDV L +E++RA R+ Sbjct: 314 TRTEAELRQARDALETLNKTLNTLAMEDGLTGLANRRQFDVALDSEYSRAARN 366 >D8IUA8.1 D8IUA8_HERSS ATP-dependent DNA ligase protein EC=6.5.1.1 Length = 856 Score = 330 bits (847), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 181/287 (63%), Positives = 201/287 (70%), Gaps = 23/287 (8%) Query: 384 RAKRDFKITPEPPPEPVARRSG---KTLSYFIQRHHARALHYDFRLEVNGVLKSWAVPKG 440 RAKRDF ITPEP R+G ++L +FIQRHHAR LHYDFRLE++GVLKSWAVPKG Sbjct: 10 RAKRDFTITPEPSGHASRSRAGAQSQSLQFFIQRHHARRLHYDFRLELDGVLKSWAVPKG 69 Query: 441 PSLDPHDKRLAVHVEDHPYDYGSFEGRIPAHQYGAGEVVLWDRGEWLPIGDPVAGLKKGH 500 PSLDPHDKRLAV VEDHP+DYGSFEG IPAHQYGAG VVLWDRG+W P GD AGL KGH Sbjct: 70 PSLDPHDKRLAVRVEDHPFDYGSFEGDIPAHQYGAGHVVLWDRGQWRPHGDARAGLAKGH 129 Query: 501 LEFELRGAKLSGRWNLVRMGKPADKDKDKDDKTKENWLLIKEKDDAAREGKQADITALRP 560 L FEL G KL GRW LVRMGKPA KENWLLIK+ D AA G+QA IT LRP Sbjct: 130 LSFELEGEKLHGRWALVRMGKPA-------ADGKENWLLIKDDDAAAASGEQAAITELRP 182 Query: 561 ESVAGTATKKTGIAPGNAAEKPVETTSKKRKPAGRAATSMPMPDKVDAQLAMLVKEAPDG 620 ESV G+ A S K P ++ PMP ++ AQLA LV AP G Sbjct: 183 ESVKDL---------GDQAPLAKARASAKAAP----DSTGPMPAQMQAQLATLVDRAPAG 229 Query: 621 DAWLSEMKFDGYRGLCRIEGGKARIFTREHLDWSKRWPQLTQALAAL 667 + WL E+KFDGYRGLCRI+ G+A I+TRE LDWS RWP L QALA L Sbjct: 230 EQWLCELKFDGYRGLCRIDHGQAAIYTREGLDWSHRWPILVQALARL 276 >A4G5V3.1 A4G5V3_HERAR Putative uncharacterized protein Length = 519 Score = 302 bits (774), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 153/370 (41%), Positives = 240/370 (64%), Gaps = 1/370 (0%) Query: 20 PAVARSRRVNVRIFASVFVGLVCLSILILHISFAWNVRVKDLDDAQISTANLSRALAEHA 79 P + +S+R++++ +VF+ V + ++ + AW+ R + + + + +T+N+++ALA+HA Sbjct: 6 PFIRKSKRLSLQATLTVFIVFVTVLLVCILALNAWHARAEKIRETETATSNMAKALAQHA 65 Query: 80 QATLISADSVLFGMVQRLEVEGMDRDSLARLYPLLASYVKELPQIQGLFVYDQSGKWMVN 139 + T+ D++L M + LE + + L R+ L V +LP + GLFVYD+ G+W+ N Sbjct: 66 EDTVGGIDNLLVSMEEMLERDSWNPLQLERMNQFLRQRVTDLPLLHGLFVYDEHGQWVAN 125 Query: 140 SMDDSPWMLNNADREYFIYHMTHEDRNPHVGEPVKSRSSGDWIIPLSRRINHPDGSFAGV 199 S + LNNADREYFI+H TH D PH+G P++SRS+GDWII +SRR+ H DG+FAGV Sbjct: 126 SQETLRTDLNNADREYFIFHRTHTDSGPHLGPPIRSRSTGDWIITVSRRLEHADGNFAGV 185 Query: 200 VLASVEVEYFLKFYRSFDIGKHGEILLATQPGILLAKWPASGEIIGKNISNSNIVSDHAS 259 VLA++ ++YF +Y+ FDIGK G I+L T G LL + P +IG +ISN + + Sbjct: 186 VLATINMQYFSAYYKDFDIGKAGAIVLTTDSGTLLVRRPFDEAVIGGDISNGPVYQFYKR 245 Query: 260 RNRNGIAIITG-ADGVKRLHSYKRLEKYPLFVTAALSYDEVLASWRTETLMQSVGVLILV 318 + +G AI+T D +R++SY+ L++YPL + A S DEVL SWR T+ + +++ Sbjct: 246 QGSSGTAILTANIDRTERIYSYRHLDRYPLLIAVAQSTDEVLESWRNSTMRFAFFSAMVL 305 Query: 319 AMLAWMGKRLINQIKLRAQAQQKLLSAREKLVEMNKTLQKMALEDGLTGVANRRQFDVTL 378 +L +G RL++QI +R +AQ +L +AR+ L N L +AL D LTG+ANRR+FD L Sbjct: 306 LLLWLLGARLVHQITVRERAQSELRTARDDLERSNGELAALALLDSLTGLANRRRFDAAL 365 Query: 379 ANEFNRAKRD 388 +EF RA R+ Sbjct: 366 DDEFARAMRN 375 >A8GGC9.1 A8GGC9_SERP5 Diguanylate cyclase Length = 516 Score = 300 bits (767), Expect = 8e-79, Method: Compositional matrix adjust. Identities = 152/358 (42%), Positives = 226/358 (63%), Gaps = 1/358 (0%) Query: 34 ASVFVGLVCLSILILHISFAWNVRVKDLDDAQISTANLSRALAEHAQATLISADSVLFGM 93 A VFV +V +++++ + WN +DL A+ +ANL+RALA+HA T + DS L + Sbjct: 24 AGVFVVIVAVTLILFNAWQIWNAHQRDLQSAENESANLARALAQHADDTFMQTDSTLSDL 83 Query: 94 VQRLEVEGMDRDSLARLYPLLASYVKELPQIQGLFVYDQSGKWMVNSMDDSPWMLNNADR 153 +R++V+G+ R L RL ++ + V LPQ+ GLFVYD G W+V S NNADR Sbjct: 84 SERIQVDGLARPQLLRLQKVMQTQVGNLPQLHGLFVYDAQGNWVVTSSGRFVQNANNADR 143 Query: 154 EYFIYHMTHEDRNPHVGEPVKSRSSGDWIIPLSRRINHPDGSFAGVVLASVEVEYFLKFY 213 EYF YH+ H ++G+ V+SRS+GD IIP+SRR NHPDGSFAGVVLA++ + YF +FY Sbjct: 144 EYFKYHLEHNSNAVYIGKVVRSRSTGDLIIPVSRRFNHPDGSFAGVVLATLYINYFRQFY 203 Query: 214 RSFDIGKHGEILLATQPGILLAKWPASGEIIGKNISNSNIVSDHASRNRNGIAIITG-AD 272 +F + + L G +L + P S IGKNIS + + + G A IT D Sbjct: 204 DTFALNSDASLNLLLADGTILYRRPYSLAAIGKNISEGVLFREILPHSEFGNATITSRYD 263 Query: 273 GVKRLHSYKRLEKYPLFVTAALSYDEVLASWRTETLMQSVGVLILVAMLAWMGKRLINQI 332 V+R++ Y R+ +YPL + A LS +VLA WR ++ + ++G L+A+L MG L+ QI Sbjct: 264 KVERIYGYSRVTRYPLVIAAGLSKKDVLADWRNDSGLFALGGATLLAILLAMGMVLMRQI 323 Query: 333 KLRAQAQQKLLSAREKLVEMNKTLQKMALEDGLTGVANRRQFDVTLANEFNRAKRDFK 390 + + +L+ R++L +N+TL+++AL DGLTG+ANRRQFD+ L NE RA R+++ Sbjct: 324 NHSVRTEAELMRTRDQLTSINRTLEELALLDGLTGLANRRQFDIALKNELMRASRNYR 381 >C6XB41.1 C6XB41_METSD DNA ligase D Length = 870 Score = 299 bits (765), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 154/297 (51%), Positives = 200/297 (67%), Gaps = 23/297 (7%) Query: 386 KRDFKITPEPPPEPVARRSGKTLSYFIQRHHARALHYDFRLEVNGVLKSWAVPKGPSLDP 445 KR+F ITPEP + +G TL+++IQRHHAR LHYDFRLE++GVLKSWA+PKGP+LDP Sbjct: 9 KRNFNITPEPSGQ--VAEAGDTLAFYIQRHHARRLHYDFRLELDGVLKSWAIPKGPTLDP 66 Query: 446 HDKRLAVHVEDHPYDYGSFEGRIPAHQYGAGEVVLWDRGEWLPIGDPVAGLKKGHLEFEL 505 +KRLAVHVEDHP +YG FEG+IP HQYGAG+V+LWD G W P+ DP G +KG L+F L Sbjct: 67 KEKRLAVHVEDHPLEYGHFEGQIPEHQYGAGKVILWDCGTWEPLEDPHVGYQKGALKFML 126 Query: 506 RGAKLSGRWNLVRMGK-PADKDKDKDDKTKENWLLIKEKDDAAREGKQADITALRPESVA 564 G KLSG+W LVRMGK PA+ + KENWLLIKEKDD A+ G+QA+IT RPES+ Sbjct: 127 HGEKLSGKWALVRMGKTPAEGSSE-----KENWLLIKEKDDVAQSGEQANITENRPESIR 181 Query: 565 GTATKKTGIAPGNAAEK----PVETTSKKRKPA----------GRAATSMPMPDKVDAQL 610 + T P +++K V +T R+ A G + PMP + QL Sbjct: 182 RLFSGDTH-RPLKSSDKARRVSVASTLSSRQSAGAHHASPDLDGEVGKTQPMPTTMQPQL 240 Query: 611 AMLVKEAPDGDAWLSEMKFDGYRGLCRIEGGKARIFTREHLDWSKRWPQLTQALAAL 667 A+L K+AP G+ WL+E+KFDGYR L R E G+ ++++R DW+ +W + AL L Sbjct: 241 ALLAKKAPVGEHWLTEVKFDGYRMLARCEDGEVKLYSRNGHDWTAKWKGIADALKQL 297