BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0014.p (742 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXU4.1 D8IXU4_HERSS Phosphodiesterase transmembrane protein 982 0.0 A2SC87.1 A2SC87_METPP Diguanylate cyclase/phosphodiesterase 712 0.0 C6WVQ3.1 C6WVQ3_METML Diguanylate cyclase/phosphodiesterase with... 637 e-180 C6XA09.1 C6XA09_METSD Diguanylate cyclase/phosphodiesterase with... 632 e-179 E4QLS1.1 E4QLS1_METS6 Diguanylate cyclase/phosphodiesterase with... 629 e-178 >D8IXU4.1 D8IXU4_HERSS Phosphodiesterase transmembrane protein Length = 797 Score = 982 bits (2538), Expect = 0.0, Method: Compositional matrix adjust. Identities = 499/731 (68%), Positives = 588/731 (80%), Gaps = 2/731 (0%) Query: 14 GPAPLASDFGFRQAIGTDDRETITSVLENHGARIGSTLSMLIGTDQSVKASTQAYPSTDL 73 G LASDFGFRQAIGTDDRETI SVL NHGARIG++++MLIG D ++AST YP TDL Sbjct: 67 GARLLASDFGFRQAIGTDDRETIASVLSNHGARIGASMAMLIGNDGQIRASTVEYPDTDL 126 Query: 74 QRSALELVSKAVVTNGASDTVIVDDNLFQIVAVPVRAPVIIGWVVMGFPVDKKLISDMRA 133 QRS+LELV KA NGAS+ +V D LFQIVAVP++APV I WVVMGFP+D +L+SDMR Sbjct: 127 QRSSLELVRKAGNGNGASENAVVGDRLFQIVAVPIKAPVTIAWVVMGFPIDHQLVSDMRE 186 Query: 134 LSSLQVSVLVSTRAG-QWQQDVSTLAKPESAMLMSQLPQSPAANSFIPQLSIADNDYSAR 192 LSSLQVS+LVS R G W DVSTL P ++ML+ ++ Q + L I N Y AR Sbjct: 187 LSSLQVSILVSQRGGVGWNADVSTLTAPAASMLLKEVGQPAMRAGGLIDLQIDGNQYRAR 246 Query: 193 VLVLAKGQGSQSAVAVLQRSISEAVAPYRRLQLILLSISIIGVIMAIFASAFVARRITSP 252 +L LA+ Q AVAVLQRS+SEAV PY+RLQLILLSI+++GV+ A ASA +ARRITSP Sbjct: 247 LLPLAQASNGQQAVAVLQRSVSEAVEPYQRLQLILLSITVLGVLGAAVASAVLARRITSP 306 Query: 253 LRALADIAKRLGTGDYRARIDIKGGDEIGKLADAFESMRSGIANRELEIRRLAYWDPLTD 312 LR LAD+AKRLG GDY + I+ DEIG+L +AFE+MR IA+REL+I RLAY D LT Sbjct: 307 LRDLADVAKRLGEGDYSEGLFIRRQDEIGRLGNAFETMRLEIASRELKISRLAYQDQLTG 366 Query: 313 LPNRVQFATLLNTAI-ERARTTGGQCHILMMDLDRFQHVNDVLGHSFGDNLLRQVGRRLE 371 LPNRVQFA LL AI E ART G C+ILMMDLDRFQ VNDVLGHSFGD+LLRQV RL Sbjct: 367 LPNRVQFADLLRDAIAEAARTPGAACYILMMDLDRFQQVNDVLGHSFGDDLLRQVALRLS 426 Query: 372 QQLERENDKVARLGGDEYAILLPATDQVEAVRQAKRILSSLEVPLSIDEQTVDLGAGIGI 431 QL K++RLGGDE+AILLP DQ AV QA +IL +LE PLS+ +QTVDLGAGIGI Sbjct: 427 AQLLHPGAKLSRLGGDEFAILLPGVDQEGAVEQALQILRALEQPLSLHQQTVDLGAGIGI 486 Query: 432 AGYPENGENSETLLSNAEVAMYVAKRRGSGFTVYEPSIDKSSQESLSLLSELRRALDRNE 491 +GYP +G++S+ LLS+AEVAMY+AKR+GSG +Y+P+ID+SSQESLSLLSELRRAL+R+E Sbjct: 487 SGYPAHGQSSDVLLSHAEVAMYIAKRKGSGLVIYDPAIDQSSQESLSLLSELRRALERDE 546 Query: 492 FLLYVQPKVDLASGRVVGAEALVRWMHPEKGFIGPDNFIPFAETTGFIRMLTSWMLGRTA 551 F+LY+QPK++L SG+VVGAEALVRW+HPEKGFIGPDNFIPFAETTGFIRMLT WM+ + A Sbjct: 547 FMLYLQPKLELCSGQVVGAEALVRWIHPEKGFIGPDNFIPFAETTGFIRMLTLWMMEQVA 606 Query: 552 ILCSELQRRGISLKFSVNLSTRDLLDQDLPQHFADILERNSLAPSSMCLEITESAIMDDP 611 L +LQ++G+ LKFSVNLSTRDLLDQ+LP FA IL+R+ L P+++CLEITESAIMDDP Sbjct: 607 RLSEQLQQQGVQLKFSVNLSTRDLLDQELPTAFAAILQRHRLQPAALCLEITESAIMDDP 666 Query: 612 VRAQLTLERLHAMGVELAIDDFGTGYSSLAYLKRLPVDELKIDKSFVMNMEHDADDAKIV 671 RAQ TLERL MG L+IDDFGTGYSSLAYLKRLPVDELKIDKSFVM M D DDAKIV Sbjct: 667 ARAQNTLERLSNMGFALSIDDFGTGYSSLAYLKRLPVDELKIDKSFVMKMAQDQDDAKIV 726 Query: 672 KSTIDLGHNMGLRVVAEGLETLAVWNLLRQMGCDQAQGYFMSKPMPGDRLIEWLEQWTPP 731 +ST+DLGHN+GLRVVAEG+E+ VW LLRQMGCDQ QGYFM KPMP + W EQW P Sbjct: 727 RSTVDLGHNLGLRVVAEGVESEEVWFLLRQMGCDQGQGYFMGKPMPVQHFLAWREQWRAP 786 Query: 732 EVPSQSENMAI 742 ++ QSENMA+ Sbjct: 787 DMLDQSENMAV 797 >A2SC87.1 A2SC87_METPP Diguanylate cyclase/phosphodiesterase Length = 816 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/734 (52%), Positives = 503/734 (68%), Gaps = 25/734 (3%) Query: 18 LASDFGFRQAIGTDDRETITSVLENHGARIGSTLSMLIGTDQSVKASTQAYPSTDLQRSA 77 LASDFGFR A+ ++D ET+ S L N G RIG++L++ ++KA+T +R Sbjct: 76 LASDFGFRAAVASNDGETLASALANQGDRIGASLAVFTDARFNLKAATH----DGAERFL 131 Query: 78 LELVSKAVVTNGASDTVIVDDNLFQIVAVPVRAPVIIGWVVMGFPVDKKLISDMRALSSL 137 L A + V++D +Q+VAVPV+AP+ IGWV MGF ++ L+ +M+ LSS+ Sbjct: 132 PTLRQLATAPDATQRLVLLDGEPYQLVAVPVKAPLTIGWVAMGFRIEASLLQEMQQLSSI 191 Query: 138 QVSVLVSTRAG---QWQQDVSTLAKPESAMLMSQ--LPQSPAANSFIPQ------LSIAD 186 V++L T+ G +W STL S L+ Q L + A + Q L++ D Sbjct: 192 DVALL--TQRGSPPRWDVLQSTLDPAASPQLVEQWLLARETQATHQMSQKERHATLTLTD 249 Query: 187 NDYS-------ARVLVLAKGQGSQSAVAVLQRSISEAVAPYRRLQLILLSISIIGVIMAI 239 + S AR + L + +G VAVL RS+ EA APYRRLQ ILL+ +++ + + Sbjct: 250 DGGSRLSGHLLARDMPLGR-EGEPQTVAVLMRSLDEATAPYRRLQWILLAFTLVAIAVFA 308 Query: 240 FASAFVARRITSPLRALADIAKRLGTGDYRARIDIKGGDEIGKLADAFESMRSGIANREL 299 S + ARRIT+PL+ LA A+RLG GDY + + DEIG+LA AFE+MR + RE Sbjct: 309 VVSVYTARRITTPLKTLAGSARRLGQGDYEQAVPARTDDEIGELAQAFETMRLAVREREG 368 Query: 300 EIRRLAYWDPLTDLPNRVQFATLLNTAIERARTTGGQCHILMMDLDRFQHVNDVLGHSFG 359 E+RRLA+ D LT LPNR QF L AI+ A+ C +LM+DLDRF+HVNDVLGH FG Sbjct: 369 EVRRLAFEDGLTQLPNREQFRADLRAAIQHAQARNEPCAVLMLDLDRFKHVNDVLGHRFG 428 Query: 360 DNLLRQVGRRLEQQLERENDKVARLGGDEYAILLPATDQVEAVRQAKRILSSLEVPLSID 419 D LL++V +RL Q+ R ND VARLGGDE+A+L+P+ D A+ A+RI + E P+S+D Sbjct: 429 DRLLQEVAKRLTQEARRSNDVVARLGGDEFAMLMPSADIALALGIAQRIQRAFERPISLD 488 Query: 420 EQTVDLGAGIGIAGYPENGENSETLLSNAEVAMYVAKRRGSGFTVYEPSIDKSSQESLSL 479 + TVDLGAGIGIA P +G ++TL+S AE+AMY AK+ G VY+ ++D SS ESLSL Sbjct: 489 DHTVDLGAGIGIACCPAHGVEADTLVSRAELAMYAAKQHQLGVKVYDAALDMSSDESLSL 548 Query: 480 LSELRRALDRNEFLLYVQPKVDLASGRVVGAEALVRWMHPEKGFIGPDNFIPFAETTGFI 539 LSELR A+DR++ LY+QPK+ LA+G V+GAEALVRW HP++G + P FIPFAE TGFI Sbjct: 549 LSELRTAVDRDQLRLYLQPKISLATGAVLGAEALVRWQHPQRGLVPPGKFIPFAEQTGFI 608 Query: 540 RMLTSWMLGRTAILCSELQRRGISLKFSVNLSTRDLLDQDLPQHFADILERNSLAPSSMC 599 R+LT WM+ R+A++ ++ +LK SVNLSTRDLLDQDLP +++ +L P SMC Sbjct: 609 RVLTGWMIERSAMVLRQMNAGAPALKISVNLSTRDLLDQDLPAKMQRLIDTLALNPGSMC 668 Query: 600 LEITESAIMDDPVRAQLTLERLHAMGVELAIDDFGTGYSSLAYLKRLPVDELKIDKSFVM 659 LEITESAIMDDP RA TLERLHAMG +L+IDDFGTGYSSLAYLKRLPVDELKID+SFV Sbjct: 669 LEITESAIMDDPQRALQTLERLHAMGFKLSIDDFGTGYSSLAYLKRLPVDELKIDQSFVF 728 Query: 660 NMEHDADDAKIVKSTIDLGHNMGLRVVAEGLETLAVWNLLRQMGCDQAQGYFMSKPMPGD 719 NME D DDAKIV+STIDL HN+GL VVAEG+ET W LL+ +GCD+AQGYF++KPMP Sbjct: 729 NMERDLDDAKIVRSTIDLAHNLGLNVVAEGIETAKAWKLLQALGCDEAQGYFVAKPMPEA 788 Query: 720 RLIEWLEQWTPPEV 733 +W+ WT P+V Sbjct: 789 LFADWIRDWTAPQV 802 >C6WVQ3.1 C6WVQ3_METML Diguanylate cyclase/phosphodiesterase with extracellular sensor Length = 781 Score = 637 bits (1643), Expect = e-180, Method: Compositional matrix adjust. Identities = 319/716 (44%), Positives = 457/716 (63%), Gaps = 2/716 (0%) Query: 14 GPAPLASDFGFRQAIGTDDRETITSVLENHGARIGSTLSMLIGTDQSVKASTQAYPSTDL 73 G LA+DFGF+ AI ++D ETI S L NH +RI + +++ +Q+ ++ ++ Sbjct: 66 GARILAADFGFKAAIASNDHETILSALINHQSRINADIAIFYSPNQNSLVISENLSENEV 125 Query: 74 QRSALELVSKAVVTNGASDTVIVDDNLFQIVAVPVRAPVIIGWVVMGFPVDKKLISDMRA 133 E++ A ++ I + +Q+VAVPV+AP+ IGWVVMGF ++ L + + Sbjct: 126 SEKIAEVIYTAQSDTQKNNFTIFKNQPYQLVAVPVKAPLTIGWVVMGFKINNSLANTLHK 185 Query: 134 LSSLQVSVLVSTRAGQWQQDVSTLAKPESAMLMSQLPQSPAAN-SFIPQLSIADNDYSAR 192 LS+L+V+ + W ST++ S ++ + A N S +L+I D + R Sbjct: 186 LSNLEVTFISQAGKNPWHSTASTMSVSASEQIVKYTTERHAFNKSNNLELTIGDVAFGTR 245 Query: 193 VLVLAKGQGSQSAVAVLQRSISEAVAPYRRLQLILLSISIIGVIMAIFASAFVARRITSP 252 + + K ++S VLQRSI EA AP++ L L L +SI+G+++ I + +V+R + P Sbjct: 246 YVSIFKNI-NESLYVVLQRSIDEATAPFQTLLLNFLILSIVGMLIFIVSILYVSRIVAQP 304 Query: 253 LRALADIAKRLGTGDYRARIDIKGGDEIGKLADAFESMRSGIANRELEIRRLAYWDPLTD 312 + LA+ A++L GDY +D+ DE+GKL+ AF SMR+ IA+RE I RLAYWD +T Sbjct: 305 IVELANTARKLEQGDYTFNVDVSRKDELGKLSSAFSSMRTAIADRERSITRLAYWDEMTG 364 Query: 313 LPNRVQFATLLNTAIERARTTGGQCHILMMDLDRFQHVNDVLGHSFGDNLLRQVGRRLEQ 372 LPNR F LN AI ++ +L+M+LDRF+ +N+VLGH FG+ LL V R+ Q Sbjct: 365 LPNRASFMKELNIAINKSEINHEPLSVLVMNLDRFKQINNVLGHDFGNQLLHAVSIRISQ 424 Query: 373 QLERENDKVARLGGDEYAILLPATDQVEAVRQAKRILSSLEVPLSIDEQTVDLGAGIGIA 432 ++ND VAR GDE+A+LLPATD AV A+++L + E P+ +++ VD+ AGIGIA Sbjct: 425 VFRKDNDVVARTSGDEFAVLLPATDASLAVNIAQKLLQAFEKPIQLEDNFVDISAGIGIA 484 Query: 433 GYPENGENSETLLSNAEVAMYVAKRRGSGFTVYEPSIDKSSQESLSLLSELRRALDRNEF 492 YP +G E LL+ AEVAM V+K + SG V++PS D S +L+L+SEL++++ NE Sbjct: 485 SYPVHGNQIEQLLNFAEVAMQVSKAQKSGPVVFQPSFDVGSNVNLTLVSELKKSIYNNEL 544 Query: 493 LLYVQPKVDLASGRVVGAEALVRWMHPEKGFIGPDNFIPFAETTGFIRMLTSWMLGRTAI 552 ++VQPKV+L S V EAL+RW HP +G I PD FIPFAE TG IR +T WM+ A Sbjct: 545 SVFVQPKVNLQSRAVRSVEALIRWKHPTRGMIFPDQFIPFAEQTGLIRDVTLWMIAEAAK 604 Query: 553 LCSELQRRGISLKFSVNLSTRDLLDQDLPQHFADILERNSLAPSSMCLEITESAIMDDPV 612 + ++G+S+ +VN+S RDL+D D P A+IL+ S + LE+TES+IMDDP Sbjct: 605 VSVAWLQKGMSIPIAVNISARDLIDSDFPNKVAEILKATGSNTSLISLEVTESSIMDDPH 664 Query: 613 RAQLTLERLHAMGVELAIDDFGTGYSSLAYLKRLPVDELKIDKSFVMNMEHDADDAKIVK 672 RA+ TL L MG++LAIDDFGTGYSSL+YLK LPV ELKIDKSFVM++E +D IV Sbjct: 665 RAKQTLLHLSEMGIKLAIDDFGTGYSSLSYLKELPVSELKIDKSFVMHIEASQNDRIIVN 724 Query: 673 STIDLGHNMGLRVVAEGLETLAVWNLLRQMGCDQAQGYFMSKPMPGDRLIEWLEQW 728 STI+L HNMGL VVAEG+E + W L++MGCD QGY+MS+P+P W +QW Sbjct: 725 STIELAHNMGLHVVAEGVENIDAWKSLQEMGCDYGQGYYMSRPIPISDFETWYQQW 780 >C6XA09.1 C6XA09_METSD Diguanylate cyclase/phosphodiesterase with extracellular sensor Length = 782 Score = 632 bits (1631), Expect = e-179, Method: Compositional matrix adjust. Identities = 340/728 (46%), Positives = 468/728 (64%), Gaps = 18/728 (2%) Query: 14 GPAPLASDFGFRQAIGTDDRETITSVLENHGARIGSTLSMLIGTDQ-----SVKAS-TQA 67 G LASD+GFRQAI + D ETI S L NH +RIG+ ++M + S K S +A Sbjct: 66 GAKILASDYGFRQAIASVDYETILSALSNHQSRIGADIAMFESSATGNLTISGKVSHVEA 125 Query: 68 YPSTDLQRSALELVSKAVVTNGASDTVIVDDNLFQIVAVPVRAPVIIGWVVMGFPVDKKL 127 P D +L+ A I + +Q+VAVPV+AP+ IGW++MGF +D L Sbjct: 126 GPIVD------KLIQDGRQQGYAQSYAIFNHQPYQLVAVPVKAPLTIGWIIMGFQIDDTL 179 Query: 128 ISDMRALSSLQVSVLVSTRAGQWQQDVSTLAKPESAMLMSQLPQSPAANSFIPQLSIADN 187 ++ LS+L V+ + + W STL + L+ + A+ + +LS+ + Sbjct: 180 AQNLHKLSNLDVTFISRSNGSDWNSMASTLGASLTEKLLEK-----ASAGRLTELSMGNA 234 Query: 188 DYSARVLVLAKGQGSQSAVAVLQRSISEAVAPYRRLQLILLSISIIGVIMAIFASAFVAR 247 DY R + + + G +S VA+LQRSI EA APY LQ LL ++++G ++ +V+R Sbjct: 235 DYGTRYVPIME-HGDESLVAILQRSIDEATAPYLVLQRNLLLLTMLGALVFALVIFYVSR 293 Query: 248 RITSPLRALADIAKRLGTGDYRARIDIKGGDEIGKLADAFESMRSGIANRELEIRRLAYW 307 RIT P+ LA A++L G++ R++ DE+GKL+ AF SM IA+RE I RLAYW Sbjct: 294 RITQPITELATTARKLEEGNFAIRLNSSREDELGKLSRAFGSMVDAIASREQSITRLAYW 353 Query: 308 DPLTDLPNRVQFATLLNTAIERARTTGGQCHILMMDLDRFQHVNDVLGHSFGDNLLRQVG 367 D LT LPNR F L A+++A+ +L+M+L+ F+ +N VLGH+ D+LLR V Sbjct: 354 DELTGLPNRASFLRELGLALQQAQDQQEHLAVLVMNLNHFKQINKVLGHAAADDLLRSVA 413 Query: 368 RRLEQQLERENDKVARLGGDEYAILLPATDQVEAVRQAKRILSSLEVPLSIDEQTVDLGA 427 +RL+ + +E+D VARLGGDE+A+LLP T A A +L LE P++I Q+VD+ Sbjct: 414 QRLQSSIRQESDLVARLGGDEFALLLPRTGIANATHVANMLLQKLEAPINIANQSVDISM 473 Query: 428 GIGIAGYPENGENSETLLSNAEVAMYVAKRRGSGFTVYEPSIDKSSQESLSLLSELRRAL 487 GIGIA YPE+ E LL NAE+AM+VAK + SG +++P+ D SSQ +LSL SELR+A+ Sbjct: 474 GIGIACYPEHASAQEKLLGNAEMAMHVAKAKQSGAVLFDPAFDISSQGNLSLASELRQAI 533 Query: 488 DRNEFLLYVQPKVDLASGRVVGAEALVRWMHPEKGFIGPDNFIPFAETTGFIRMLTSWML 547 NE LYVQPK+DL +G++ EAL+RW HP+KG + PD FIPFAE +G I +++ W+L Sbjct: 534 ATNELALYVQPKIDLQNGKISAVEALIRWRHPQKGLMFPDQFIPFAEQSGLISLISLWVL 593 Query: 548 GRTAILCSELQRRGISLKFSVNLSTRDLLDQDLPQHFADILERNSLAPSSMCLEITESAI 607 A + ++ GI +VNLSTRDL+DQDLP + + LA + LEITES++ Sbjct: 594 AEAARVEVAWRKLGIDAPIAVNLSTRDLIDQDLPHKILTLHQDAGLALGGITLEITESSM 653 Query: 608 MDDPVRAQLTLERLHAMGVELAIDDFGTGYSSLAYLKRLPVDELKIDKSFVMNMEHDADD 667 MDDP RAQ TLERL MG++L+IDDFGTGYSSLAYLKRLPV ELKIDKSFV+ ME D +D Sbjct: 654 MDDPQRAQQTLERLSDMGLQLSIDDFGTGYSSLAYLKRLPVSELKIDKSFVLKMEEDEND 713 Query: 668 AKIVKSTIDLGHNMGLRVVAEGLETLAVWNLLRQMGCDQAQGYFMSKPMPGDRLIEWLEQ 727 KIV+STIDLGHN+ L+VVAEG+E+ A W+LL MGCD QGY +SKPMP WL++ Sbjct: 714 RKIVRSTIDLGHNLNLKVVAEGIESRAAWDLLASMGCDFGQGYHISKPMPAADFPAWLQR 773 Query: 728 WTPPEVPS 735 W E+ + Sbjct: 774 WQAQELQT 781 >E4QLS1.1 E4QLS1_METS6 Diguanylate cyclase/phosphodiesterase with extracellular sensor Length = 782 Score = 629 bits (1623), Expect = e-178, Method: Compositional matrix adjust. Identities = 339/728 (46%), Positives = 466/728 (64%), Gaps = 18/728 (2%) Query: 14 GPAPLASDFGFRQAIGTDDRETITSVLENHGARIGSTLSMLIGTDQ-----SVKAS-TQA 67 G LASD+GFRQAI + D ETI S L NH +RIG+ ++M + S K S +A Sbjct: 66 GAKILASDYGFRQAIASVDYETILSALSNHQSRIGADIAMFESSSTGNLTISGKVSHVEA 125 Query: 68 YPSTDLQRSALELVSKAVVTNGASDTVIVDDNLFQIVAVPVRAPVIIGWVVMGFPVDKKL 127 P D +L+ A I + +Q+VAVPV+AP+ IGW++MGF +D L Sbjct: 126 GPIVD------KLIQDGRQQGYAQSYAIFNHQPYQLVAVPVKAPLTIGWIIMGFQIDDTL 179 Query: 128 ISDMRALSSLQVSVLVSTRAGQWQQDVSTLAKPESAMLMSQLPQSPAANSFIPQLSIADN 187 ++ LS+L V+ + + W STL + L+ + A+ + +LS+ + Sbjct: 180 AQNLHKLSNLDVTFISRSNGSDWNSMASTLGASLTEKLLEK-----ASAGRLTELSMGNA 234 Query: 188 DYSARVLVLAKGQGSQSAVAVLQRSISEAVAPYRRLQLILLSISIIGVIMAIFASAFVAR 247 DY R + + + G +S VA+LQRSI EA APY LQ LL ++++G ++ +V+R Sbjct: 235 DYGTRYVPIME-HGDESLVAILQRSIDEATAPYLVLQRNLLLLTMLGALVFALVIFYVSR 293 Query: 248 RITSPLRALADIAKRLGTGDYRARIDIKGGDEIGKLADAFESMRSGIANRELEIRRLAYW 307 RIT P+ LA A++L G++ R++ DE+GKL+ AF SM IA+RE I RLAYW Sbjct: 294 RITQPITELAATARKLEEGNFAIRLNSSREDELGKLSRAFGSMVDAIASREQSITRLAYW 353 Query: 308 DPLTDLPNRVQFATLLNTAIERARTTGGQCHILMMDLDRFQHVNDVLGHSFGDNLLRQVG 367 D LT LPNR F L A+++A+ +L+M+L+ F+ +N VLGH+ D+LLR V Sbjct: 354 DELTGLPNRASFLRELGLALQQAQDQQEHLAVLVMNLNHFKQINKVLGHAAADDLLRGVA 413 Query: 368 RRLEQQLERENDKVARLGGDEYAILLPATDQVEAVRQAKRILSSLEVPLSIDEQTVDLGA 427 +RL+ + +E+D VARLGGDE+A+LLP T A A +L LE P++I Q+VD+ Sbjct: 414 QRLQSSIRQESDLVARLGGDEFALLLPRTGIANATHVANMLLQKLEAPINIANQSVDISM 473 Query: 428 GIGIAGYPENGENSETLLSNAEVAMYVAKRRGSGFTVYEPSIDKSSQESLSLLSELRRAL 487 GIGIA YPE+ E LL NAE+AM+VAK + SG +++P+ D SSQ +LSL SELR+A+ Sbjct: 474 GIGIACYPEHASAQEKLLGNAEMAMHVAKAKQSGAVLFDPAFDISSQGNLSLASELRQAI 533 Query: 488 DRNEFLLYVQPKVDLASGRVVGAEALVRWMHPEKGFIGPDNFIPFAETTGFIRMLTSWML 547 NE LYVQPK+DL +G++ EAL+RW HP+KG + PD FIPFAE +G I +++ W+L Sbjct: 534 ATNELALYVQPKIDLQNGKISAVEALIRWRHPQKGLMFPDQFIPFAEQSGLISLVSLWVL 593 Query: 548 GRTAILCSELQRRGISLKFSVNLSTRDLLDQDLPQHFADILERNSLAPSSMCLEITESAI 607 A + ++ GI +VNLSTRDL+DQDLP + + L + LEITES++ Sbjct: 594 AEAARVEVAWRKLGIDAPIAVNLSTRDLIDQDLPHKILTLHQDAGLVLGGITLEITESSM 653 Query: 608 MDDPVRAQLTLERLHAMGVELAIDDFGTGYSSLAYLKRLPVDELKIDKSFVMNMEHDADD 667 MDDP RAQ TLERL MG++L+IDDFGTGYSSLAYLKRLPV ELKIDKSFV+ ME D D Sbjct: 654 MDDPQRAQQTLERLSDMGLQLSIDDFGTGYSSLAYLKRLPVSELKIDKSFVLKMEEDESD 713 Query: 668 AKIVKSTIDLGHNMGLRVVAEGLETLAVWNLLRQMGCDQAQGYFMSKPMPGDRLIEWLEQ 727 KIV+STIDLGHN+ L+VVAEG+E+ A W+LL MGCD QGY +SKPMP WL++ Sbjct: 714 RKIVRSTIDLGHNLNLKVVAEGIESRAAWDLLASMGCDFGQGYHISKPMPAADFPAWLQR 773 Query: 728 WTPPEVPS 735 W E+ + Sbjct: 774 WQAQELQT 781