BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0007.p (430 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXU8.1 D8IXU8_HERSS Multidrug resistance A (Translocase) trans... 475 e-132 B5S1G1.1 B5S1G1_RALSO Multidrug resistance protein a (Translocase) 398 e-108 B5SLR2.1 B5SLR2_RALSO Multidrug resistance protein a (Translocase) 397 e-108 A3S050.1 A3S050_RALSO Probable multidrug resistance protein A (E... 397 e-108 D5W6Y3.1 D5W6Y3_BURSC Efflux pump membrane protein 392 e-107 >D8IXU8.1 D8IXU8_HERSS Multidrug resistance A (Translocase) transmembrane secretion protein Length = 406 Score = 475 bits (1223), Expect = e-132, Method: Compositional matrix adjust. Identities = 264/301 (87%), Positives = 288/301 (95%) Query: 19 NGNGNGKRKRQLLLLTLVLIIVAIGLFLYWFLHARFFEETDDAYVGGNVVQISAQVGGTV 78 N NGNGKRKRQL+LLTLVL+++A+ FLYWFLHARFFEETDDAYVGGNVVQISAQVGGTV Sbjct: 13 NNNGNGKRKRQLILLTLVLLVIAVACFLYWFLHARFFEETDDAYVGGNVVQISAQVGGTV 72 Query: 79 TAIKADDTQVVKAGQQLVSLDAADTKLALAQAEAALAQAVRQTRQTFLNNDTLAANVTAA 138 A+KADDTQVVKAGQQLV+LDAADT+LAL QA+AALAQAVRQTRQ FLNNDTLAANV AA Sbjct: 73 VAVKADDTQVVKAGQQLVALDAADTRLALDQAQAALAQAVRQTRQLFLNNDTLAANVAAA 132 Query: 139 ETNLARTRDDLQRRQAGIASGAVSQEDLAHAQDAVKNANASLEQARASLAANRALTDHTS 198 ++NLAR R+DLQRRQAG++SGAVSQED++HA+DAVK+A A+L+QARA+ AANRALTDHTS Sbjct: 133 DSNLARAREDLQRRQAGLSSGAVSQEDVSHARDAVKSAVAALDQARAAAAANRALTDHTS 192 Query: 199 VTEHPNVLQAATQVRNAYLNYARVNIVAPVSGFVSKRSVQLGQRIAPGNPLMAIVPLEQI 258 VTEHPNVLQAAT VRNAYLNYARVNIVAPVSGFVSKRSVQ+GQRIA GNPLMAIVPLEQI Sbjct: 193 VTEHPNVLQAATAVRNAYLNYARVNIVAPVSGFVSKRSVQVGQRIAAGNPLMAIVPLEQI 252 Query: 259 WIDANFKEGQLKHIRIGQPVEVIADVYGSSVKYKGTVVGFSAGTGGAFSLLPAQNATGNW 318 WIDANFKE QL+HIRIGQPVEVIADVYGSSVKYKGTV+GFSAGTGGAFSLLPAQNATGNW Sbjct: 253 WIDANFKESQLQHIRIGQPVEVIADVYGSSVKYKGTVIGFSAGTGGAFSLLPAQNATGNW 312 Query: 319 I 319 I Sbjct: 313 I 313 >B5S1G1.1 B5S1G1_RALSO Multidrug resistance protein a (Translocase) Length = 428 Score = 398 bits (1022), Expect = e-108, Method: Compositional matrix adjust. Identities = 189/303 (62%), Positives = 238/303 (78%) Query: 17 TPNGNGNGKRKRQLLLLTLVLIIVAIGLFLYWFLHARFFEETDDAYVGGNVVQISAQVGG 76 TPNGNGNGKRKR L L L++ IG LYW L+ R+FE TDDAYV GNVVQ++ QV G Sbjct: 22 TPNGNGNGKRKRMLTTLASALVVAGIGYGLYWGLYGRWFESTDDAYVQGNVVQVTPQVAG 81 Query: 77 TVTAIKADDTQVVKAGQQLVSLDAADTKLALAQAEAALAQAVRQTRQTFLNNDTLAANVT 136 TV AI+ADDTQ+V +GQ L+ LD AD ++AL Q+EAALAQAVRQ R + N A+ + Sbjct: 82 TVVAIRADDTQLVTSGQPLIELDRADARVALEQSEAALAQAVRQVRTLYSNTGAYASTLA 141 Query: 137 AAETNLARTRDDLQRRQAGIASGAVSQEDLAHAQDAVKNANASLEQARASLAANRALTDH 196 E++LA+ R+DL RR+ +GAVSQE++AHAQ +++ A A++E A+ L ANR LTD Sbjct: 142 MRESDLAKAREDLTRRKQIAGTGAVSQEEIAHAQISLQAAEAAVETAKEQLQANRVLTDQ 201 Query: 197 TSVTEHPNVLQAATQVRNAYLNYARVNIVAPVSGFVSKRSVQLGQRIAPGNPLMAIVPLE 256 T++ HPNVLQAA +VR AYL YAR ++ A V+G+V+KRSVQ+GQR+APG PLMAIVPL+ Sbjct: 202 TTLERHPNVLQAAAKVREAYLAYARTSLPASVTGYVAKRSVQVGQRVAPGTPLMAIVPLD 261 Query: 257 QIWIDANFKEGQLKHIRIGQPVEVIADVYGSSVKYKGTVVGFSAGTGGAFSLLPAQNATG 316 Q+W+DANFKE Q++H+R+GQPVE++ADVYG SV Y G VVGFSAGTG AFSLLPAQNATG Sbjct: 262 QLWVDANFKEVQVRHMRVGQPVELVADVYGGSVTYHGKVVGFSAGTGSAFSLLPAQNATG 321 Query: 317 NWI 319 NWI Sbjct: 322 NWI 324 >B5SLR2.1 B5SLR2_RALSO Multidrug resistance protein a (Translocase) Length = 428 Score = 397 bits (1020), Expect = e-108, Method: Compositional matrix adjust. Identities = 189/303 (62%), Positives = 238/303 (78%) Query: 17 TPNGNGNGKRKRQLLLLTLVLIIVAIGLFLYWFLHARFFEETDDAYVGGNVVQISAQVGG 76 TPNGNGNGKRKR L L L++ IG LYW L+ R+FE TDDAYV GNVVQ++ QV G Sbjct: 22 TPNGNGNGKRKRMLTTLASALVVAGIGYGLYWGLYGRWFESTDDAYVQGNVVQVTPQVAG 81 Query: 77 TVTAIKADDTQVVKAGQQLVSLDAADTKLALAQAEAALAQAVRQTRQTFLNNDTLAANVT 136 TV AI+ADDTQ+V +GQ L+ LD AD ++AL Q+EAALAQAVRQ R + N A+ + Sbjct: 82 TVVAIRADDTQLVTSGQPLIELDRADARVALEQSEAALAQAVRQVRTLYSNTGAYASTLA 141 Query: 137 AAETNLARTRDDLQRRQAGIASGAVSQEDLAHAQDAVKNANASLEQARASLAANRALTDH 196 E++LA+ R+DL RR+ +GAVSQE++AHAQ +++ A A++E A+ L ANR LTD Sbjct: 142 MRESDLAKAREDLTRRKQIAGTGAVSQEEIAHAQISLQAAEAAVETAKEQLQANRVLTDQ 201 Query: 197 TSVTEHPNVLQAATQVRNAYLNYARVNIVAPVSGFVSKRSVQLGQRIAPGNPLMAIVPLE 256 T++ HPNVLQAA +VR AYL YAR ++ A V+G+V+KRSVQ+GQR+APG PLMAIVPL+ Sbjct: 202 TTLERHPNVLQAAAKVREAYLAYARTSLPASVTGYVAKRSVQVGQRVAPGTPLMAIVPLD 261 Query: 257 QIWIDANFKEGQLKHIRIGQPVEVIADVYGSSVKYKGTVVGFSAGTGGAFSLLPAQNATG 316 Q+W+DANFKE Q++H+R+GQPVE++ADVYG SV Y G VVGFSAGTG AFSLLPAQNATG Sbjct: 262 QLWVDANFKEVQVRHMRVGQPVELVADVYGGSVTYHGKVVGFSAGTGSAFSLLPAQNATG 321 Query: 317 NWI 319 NWI Sbjct: 322 NWI 324 >A3S050.1 A3S050_RALSO Probable multidrug resistance protein A (EmrA) MLYD family Length = 428 Score = 397 bits (1020), Expect = e-108, Method: Compositional matrix adjust. Identities = 189/303 (62%), Positives = 238/303 (78%) Query: 17 TPNGNGNGKRKRQLLLLTLVLIIVAIGLFLYWFLHARFFEETDDAYVGGNVVQISAQVGG 76 TPNGNGNGKRKR L L L++ IG LYW L+ R+FE TDDAYV GNVVQ++ QV G Sbjct: 22 TPNGNGNGKRKRMLTTLASALVVAGIGYGLYWGLYGRWFESTDDAYVQGNVVQVTPQVAG 81 Query: 77 TVTAIKADDTQVVKAGQQLVSLDAADTKLALAQAEAALAQAVRQTRQTFLNNDTLAANVT 136 TV AI+ADDTQ+V +GQ L+ LD AD ++AL Q+EAALAQAVRQ R + N A+ + Sbjct: 82 TVVAIRADDTQLVTSGQPLIELDRADARVALEQSEAALAQAVRQVRTLYSNTGAYASTLA 141 Query: 137 AAETNLARTRDDLQRRQAGIASGAVSQEDLAHAQDAVKNANASLEQARASLAANRALTDH 196 E++LA+ R+DL RR+ +GAVSQE++AHAQ +++ A A++E A+ L ANR LTD Sbjct: 142 MRESDLAKAREDLTRRKQIAGTGAVSQEEIAHAQISLQAAEAAVETAKEQLQANRVLTDQ 201 Query: 197 TSVTEHPNVLQAATQVRNAYLNYARVNIVAPVSGFVSKRSVQLGQRIAPGNPLMAIVPLE 256 T++ HPNVLQAA +VR AYL YAR ++ A V+G+V+KRSVQ+GQR+APG PLMAIVPL+ Sbjct: 202 TTLERHPNVLQAAAKVREAYLAYARTSLPASVTGYVAKRSVQVGQRVAPGTPLMAIVPLD 261 Query: 257 QIWIDANFKEGQLKHIRIGQPVEVIADVYGSSVKYKGTVVGFSAGTGGAFSLLPAQNATG 316 Q+W+DANFKE Q++H+R+GQPVE++ADVYG SV Y G VVGFSAGTG AFSLLPAQNATG Sbjct: 262 QLWVDANFKEVQVRHMRVGQPVELVADVYGGSVTYHGKVVGFSAGTGSAFSLLPAQNATG 321 Query: 317 NWI 319 NWI Sbjct: 322 NWI 324 >D5W6Y3.1 D5W6Y3_BURSC Efflux pump membrane protein Length = 413 Score = 392 bits (1007), Expect = e-107, Method: Compositional matrix adjust. Identities = 191/305 (62%), Positives = 238/305 (78%) Query: 15 ANTPNGNGNGKRKRQLLLLTLVLIIVAIGLFLYWFLHARFFEETDDAYVGGNVVQISAQV 74 A P NGKRKR + LL +V++I A+ LY+FL ARF E+TDDAYV GNVVQI+ QV Sbjct: 8 ATPPQAANNGKRKRMMTLLVIVILIAAVAYGLYYFLDARFHEDTDDAYVSGNVVQITPQV 67 Query: 75 GGTVTAIKADDTQVVKAGQQLVSLDAADTKLALAQAEAALAQAVRQTRQTFLNNDTLAAN 134 GTV A+ ADDTQVVKAG LV LD AD ++AL QAEA LAQ VRQ R F ++ A Sbjct: 68 TGTVIAVNADDTQVVKAGDPLVVLDPADARVALEQAEANLAQVVRQVRGLFADDSQYEAR 127 Query: 135 VTAAETNLARTRDDLQRRQAGIASGAVSQEDLAHAQDAVKNANASLEQARASLAANRALT 194 V A++ +L+R +DDL+RR +GAVSQE+++HA+DAVK+A A+L+ A+ LAANRALT Sbjct: 128 VAASQADLSRAQDDLKRRMTVAQTGAVSQEEISHARDAVKSAQAALDAAKQQLAANRALT 187 Query: 195 DHTSVTEHPNVLQAATQVRNAYLNYARVNIVAPVSGFVSKRSVQLGQRIAPGNPLMAIVP 254 +T++ HPNV AA ++R+AYLN+AR + APV+G+V+KRSVQ+GQR++PG PLMAIVP Sbjct: 188 ANTTIANHPNVQAAAAKLRDAYLNHARNTLPAPVTGYVAKRSVQVGQRVSPGTPLMAIVP 247 Query: 255 LEQIWIDANFKEGQLKHIRIGQPVEVIADVYGSSVKYKGTVVGFSAGTGGAFSLLPAQNA 314 L +W+DANFKE QLKH+RIGQPVE+ ADVYGSSV Y G V+GFSAGTG AFSLLPAQNA Sbjct: 248 LHDVWVDANFKEVQLKHMRIGQPVELTADVYGSSVPYHGKVIGFSAGTGSAFSLLPAQNA 307 Query: 315 TGNWI 319 TGNWI Sbjct: 308 TGNWI 312