BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0006.p (521 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXU9.1 D8IXU9_HERSS Multidrug resistance B (Translocase) trans... 875 0.0 E1TFQ8.1 E1TFQ8_BURSG Drug resistance transporter, EmrB/QacA sub... 721 0.0 B2T4B8.1 B2T4B8_BURPP Drug resistance transporter, EmrB/QacA sub... 718 0.0 B2T5F4.1 B2T5F4_BURPP Drug resistance transporter, EmrB/QacA sub... 716 0.0 E8YR94.1 E8YR94_9BURK Drug resistance transporter, EmrB/QacA sub... 714 0.0 >D8IXU9.1 D8IXU9_HERSS Multidrug resistance B (Translocase) transmembrane protein Length = 524 Score = 875 bits (2262), Expect = 0.0, Method: Compositional matrix adjust. Identities = 449/524 (85%), Positives = 491/524 (93%), Gaps = 3/524 (0%) Query: 1 MASSP---QTYTPPPPLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDE 57 MA+SP Q YTPPPPLTG LVLGTL VSLAVFMNVLDSSIANVAIPTISGNLGVS+DE Sbjct: 1 MATSPTPSQAYTPPPPLTGANLVLGTLSVSLAVFMNVLDSSIANVAIPTISGNLGVSVDE 60 Query: 58 GTWVITSFAAANAISIPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARV 117 GTWVITSFAAANAISIPLTGWLTQR+GAVRLFV+SVLLFVLASWLCGLAPTLPILL ARV Sbjct: 61 GTWVITSFAAANAISIPLTGWLTQRLGAVRLFVTSVLLFVLASWLCGLAPTLPILLAARV 120 Query: 118 LQGLVAGPMVPLSQSLLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWI 177 LQGLVAGPMVPLSQSLLLGAYPKSK+SFALALWGMTAVVAPVAGPALGGWITD+YTWPWI Sbjct: 121 LQGLVAGPMVPLSQSLLLGAYPKSKSSFALALWGMTAVVAPVAGPALGGWITDSYTWPWI 180 Query: 178 FYINIPVGLLAAGMTMAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFA 237 FYINIPVGL+AAG+T+AIY+ RE+PTHKLPID IGL LL+TWVAAFQIMLDKGKDLDWFA Sbjct: 181 FYINIPVGLIAAGVTLAIYRSRETPTHKLPIDKIGLALLVTWVAAFQIMLDKGKDLDWFA 240 Query: 238 SPTIVTLGIIAAVAFAYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVL 297 SPTIVTLGIIA +AFAYFV+WELNNDHPVVDLRLFGRRNF GGT+AISIGYGVFFGNLV+ Sbjct: 241 SPTIVTLGIIALIAFAYFVVWELNNDHPVVDLRLFGRRNFAGGTIAISIGYGVFFGNLVI 300 Query: 298 LPQWLQQYLGYRSIDSGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFM 357 LPQWLQQYLGYRSIDSGLSTAPIGIFAVILMPLIG+FLP +DARKVATASF+GFA VF++ Sbjct: 301 LPQWLQQYLGYRSIDSGLSTAPIGIFAVILMPLIGRFLPLVDARKVATASFIGFAIVFWL 360 Query: 358 RSRYNLEVDQWTVILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGA 417 RSRYNL+VDQ TVILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGA Sbjct: 361 RSRYNLQVDQMTVILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGA 420 Query: 418 IGTSVATTAWNNRTIVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNA 477 +GTS++TTAWNNR+I+HHAQLTEHATPYS LQ+ +NL+ G++ EQ G++ER + Sbjct: 421 VGTSISTTAWNNRSIMHHAQLTEHATPYSPWLQETVNNLSSTLGLNAEQTAGMLERTITF 480 Query: 478 QAAMIGINDIFWLSGVIFLVIIPVIWIIKPAKGNAGAEAAAAAH 521 QAAM+GINDIF++S VIF+VIIP+IWIIKP+KG AGA A+AAH Sbjct: 481 QAAMLGINDIFYVSAVIFIVIIPLIWIIKPSKGGAGAAEASAAH 524 >E1TFQ8.1 E1TFQ8_BURSG Drug resistance transporter, EmrB/QacA subfamily Length = 529 Score = 721 bits (1860), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/496 (69%), Positives = 419/496 (84%) Query: 14 LTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAANAISI 73 L GG+LVL T+ V+LA FMNVLD+SIANVAIPTISGNLGVS+DEGTWVIT FAAANA+SI Sbjct: 23 LQGGQLVLATIAVALATFMNVLDTSIANVAIPTISGNLGVSVDEGTWVITVFAAANAVSI 82 Query: 74 PLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPLSQSL 133 PLTGWLTQRIG V+LFV ++L+FVLASWLCG+APTLP+LL ARV QG VAGP++PLSQ++ Sbjct: 83 PLTGWLTQRIGQVKLFVGAILMFVLASWLCGIAPTLPVLLLARVFQGAVAGPLIPLSQAI 142 Query: 134 LLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAAGMTM 193 LLG+YPK KAS ALALW MTA V P+AGPALGGWITD+Y+W WIFYINIPVGL AAG+T Sbjct: 143 LLGSYPKEKASTALALWAMTATVGPIAGPALGGWITDSYSWSWIFYINIPVGLFAAGVTW 202 Query: 194 AIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAAVAFA 253 IY+ RESPT K PID +GL LLITWVAA QIMLDKGKDLDWFASP IV LG+ A V+FA Sbjct: 203 MIYRTRESPTRKPPIDVVGLGLLITWVAALQIMLDKGKDLDWFASPVIVILGLTALVSFA 262 Query: 254 YFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYRSIDS 313 +F++WEL ++P+VDLRLF RNF GGT+AIS+ YGVFFGNLVLLPQW+Q+YL YRS+D+ Sbjct: 263 FFLLWELTEENPIVDLRLFRERNFLGGTIAISVAYGVFFGNLVLLPQWMQEYLNYRSVDA 322 Query: 314 GLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNLEVDQWTVILP 373 GL TAP+GIFAVIL P++G+ LPR DAR ++T +FVGFA VF+MRS+Y +E+D W ++LP Sbjct: 323 GLVTAPLGIFAVILAPVMGRVLPRSDARIISTMAFVGFAIVFYMRSKYVIEIDTWHLVLP 382 Query: 374 TLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNNRTIV 433 TLLQGIP A+FFVPLT ++LSG PP++IPAAAGLS+FVRVFCGA+GTSVA AWNNRT++ Sbjct: 383 TLLQGIPMALFFVPLTSIILSGQPPQKIPAAAGLSNFVRVFCGAVGTSVAGNAWNNRTVL 442 Query: 434 HHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFWLSGV 493 HH +LTE A+ + Q + ++T+ A L + N+ QAAM+G+NDIF++S V Sbjct: 443 HHERLTERASVNNPLFNQQIDSTQSLLHLNTQSAHALFDFNVTTQAAMMGLNDIFFVSAV 502 Query: 494 IFLVIIPVIWIIKPAK 509 IF++IIP+IWI +PAK Sbjct: 503 IFILIIPLIWITRPAK 518 >B2T4B8.1 B2T4B8_BURPP Drug resistance transporter, EmrB/QacA subfamily Length = 520 Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/498 (68%), Positives = 414/498 (83%) Query: 12 PPLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAANAI 71 PPLTGGKLVL TL V+LA FMNVLDSSIANVAIPTI+GNLGVS+DEGTWVIT FAAANAI Sbjct: 11 PPLTGGKLVLATLAVALATFMNVLDSSIANVAIPTIAGNLGVSVDEGTWVITLFAAANAI 70 Query: 72 SIPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPLSQ 131 +IPLTGWL QR+G ++LFV ++LLFVL+SWLCG+APTLP+LL AR+LQG VAGP++PLSQ Sbjct: 71 AIPLTGWLVQRVGQIKLFVWAILLFVLSSWLCGIAPTLPVLLAARILQGAVAGPLIPLSQ 130 Query: 132 SLLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAAGM 191 ++LLG+YPK K++ ALALW MTA V P+AGPALGGWITD+Y+W WIFYINIPVGL AAG+ Sbjct: 131 AILLGSYPKEKSATALALWAMTATVGPIAGPALGGWITDSYSWSWIFYINIPVGLFAAGV 190 Query: 192 TMAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAAVA 251 T AIY+ RE+PT +LPID +GLL LI WV + QIMLDKGKDLDWF SP I+ L + AA++ Sbjct: 191 TWAIYRTRETPTKRLPIDKVGLLSLIAWVGSLQIMLDKGKDLDWFNSPVIIALTVFAAIS 250 Query: 252 FAYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYRSI 311 FA+FVIWEL +P+VDLRLFG+RNF GGT+AIS+ Y VFF NLVLLPQW+Q+YL YRS+ Sbjct: 251 FAFFVIWELTEKNPIVDLRLFGKRNFLGGTIAISVAYAVFFSNLVLLPQWMQEYLNYRSV 310 Query: 312 DSGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNLEVDQWTVI 371 D+GL+TAP+GIFAVIL P++ K +P+ DAR +AT +FVGFA VFFMRS Y VD WT++ Sbjct: 311 DAGLATAPLGIFAVILAPVMAKIMPKSDARVLATLAFVGFAGVFFMRSNYTTGVDTWTLV 370 Query: 372 LPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNNRT 431 LPTLLQGIPTA+FFVPLT ++LSGL P+RIPAAAGLS+F RVF GA+GTS+A+T WN+RT Sbjct: 371 LPTLLQGIPTALFFVPLTAIILSGLTPDRIPAAAGLSNFARVFAGAVGTSLASTGWNDRT 430 Query: 432 IVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFWLS 491 I+HH+QL E + + L G S QA ER++ QAAM+G+NDIFWLS Sbjct: 431 ILHHSQLAEQTSVNNPTYTAALDALQSTLGGSHAQAMAFFERSMTTQAAMLGLNDIFWLS 490 Query: 492 GVIFLVIIPVIWIIKPAK 509 VIF++IIP+IW+ KP + Sbjct: 491 AVIFVLIIPLIWVTKPDR 508 >B2T5F4.1 B2T5F4_BURPP Drug resistance transporter, EmrB/QacA subfamily Length = 517 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/518 (65%), Positives = 422/518 (81%), Gaps = 2/518 (0%) Query: 4 SPQTYTPPPPLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVIT 63 +P T PPPLTGGKLVL TL V+LA FMNVLDSSIANVAIPTISGNLGVS+DEGTWVIT Sbjct: 2 NPSTQLAPPPLTGGKLVLATLAVALATFMNVLDSSIANVAIPTISGNLGVSVDEGTWVIT 61 Query: 64 SFAAANAISIPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVA 123 F+AANA++IPLTGWLTQR+G +RLFVS++LLFV +SWLCG+AP L +LL ARVLQG VA Sbjct: 62 LFSAANAVAIPLTGWLTQRVGQIRLFVSAILLFVFSSWLCGIAPNLIVLLAARVLQGAVA 121 Query: 124 GPMVPLSQSLLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIP 183 GP++PLSQ++LLG+YPK ++S AL+LW MTA V P+AGPALGGWITD+Y+W WIFYINIP Sbjct: 122 GPLIPLSQAILLGSYPKERSSTALSLWAMTATVGPIAGPALGGWITDSYSWSWIFYINIP 181 Query: 184 VGLLAAGMTMAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVT 243 VGL AA +T IY+DR+S T KLPID +GLL LI WVA+ QIMLDKGKDLDWF SP I Sbjct: 182 VGLFAAAVTWMIYRDRDSSTRKLPIDKVGLLSLIAWVASLQIMLDKGKDLDWFNSPVICV 241 Query: 244 LGIIAAVAFAYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQ 303 L ++A ++F +F+IWE +P+V+LRLF RNF GGT+AIS+ Y VFF NLV+LPQW+Q Sbjct: 242 LAVVAGISFLFFLIWEFTEKNPIVELRLFAGRNFRGGTIAISVAYAVFFSNLVILPQWIQ 301 Query: 304 QYLGYRSIDSGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNL 363 YLGYRS+D+GL TAP+GIFAV+L P++ K +P+ DAR +AT +F+GFA VFFMRS Y Sbjct: 302 GYLGYRSVDAGLVTAPLGIFAVLLAPVMAKIMPKSDARVLATLAFLGFAGVFFMRSHYTT 361 Query: 364 EVDQWTVILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVA 423 VD +T++LPTLLQGIP A+FF PLT ++LSGL PERIPAAAGLS+FVRVF G +GTS+ Sbjct: 362 SVDPYTLVLPTLLQGIPMALFFTPLTAIILSGLSPERIPAAAGLSNFVRVFAGGVGTSLI 421 Query: 424 TTAWNNRTIVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIG 483 +T WN+RTI+HHAQL E ++ + + +NL G + EQAT ER+LNAQAAM+G Sbjct: 422 STGWNDRTILHHAQLAEQSSVNNPSYMSAIANLQTILGGNLEQATAFFERSLNAQAAMLG 481 Query: 484 INDIFWLSGVIFLVIIPVIWIIKPAKGNAGAEAAAAAH 521 +NDIFWLS +IF+VIIP++W+ +P K + G AAA AH Sbjct: 482 LNDIFWLSSLIFIVIIPLVWLTRPGKVDGG--AAAGAH 517 >E8YR94.1 E8YR94_9BURK Drug resistance transporter, EmrB/QacA subfamily Length = 556 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/496 (68%), Positives = 417/496 (84%) Query: 14 LTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAANAISI 73 L GG+LVL T+ V+LA FMNVLD+SIANVAIPTISGNLGVS+DEGTWVIT FAAANA+SI Sbjct: 51 LQGGQLVLATIAVALATFMNVLDTSIANVAIPTISGNLGVSVDEGTWVITVFAAANAVSI 110 Query: 74 PLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPLSQSL 133 PLTGWLTQRIG V+LFV ++L FVLASWLCG+APTLP+LL ARV QG VAGP++PLSQ++ Sbjct: 111 PLTGWLTQRIGQVKLFVGAILSFVLASWLCGIAPTLPMLLLARVFQGAVAGPLIPLSQAI 170 Query: 134 LLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAAGMTM 193 LLG+YPK KAS AL+LW MTA V P+AGPALGGWITD+Y+W WIFYINIPVG+ AAG+T Sbjct: 171 LLGSYPKEKASTALSLWAMTATVGPIAGPALGGWITDSYSWSWIFYINIPVGIFAAGVTW 230 Query: 194 AIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAAVAFA 253 IY+ RESPT K PID +GL LLITWVA+ QIMLDKGKDLDWFASP IV LG+ A ++FA Sbjct: 231 MIYRTRESPTRKPPIDVVGLGLLITWVASLQIMLDKGKDLDWFASPVIVILGLTALISFA 290 Query: 254 YFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYRSIDS 313 +F++WEL ++P+VDLRLF RNF GGTVAIS+ YGVFFGNLVLLPQW+Q+YL YRS+D+ Sbjct: 291 FFLVWELTEENPIVDLRLFRERNFLGGTVAISVAYGVFFGNLVLLPQWMQEYLNYRSVDA 350 Query: 314 GLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNLEVDQWTVILP 373 GL TAP+G+FAVIL P++G+ LPR DAR ++T +FVGFA VF+MRS+Y +E+D W +++P Sbjct: 351 GLVTAPLGVFAVILAPVMGRVLPRSDARIISTMAFVGFAIVFYMRSKYVIEIDTWHLVIP 410 Query: 374 TLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNNRTIV 433 TLLQGIP A+FFVPLT ++LSG PP +IPAAAGLS+FVRVFCGA+GTSVA AWNNRT++ Sbjct: 411 TLLQGIPMALFFVPLTAIILSGQPPHKIPAAAGLSNFVRVFCGAVGTSVAGNAWNNRTVL 470 Query: 434 HHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFWLSGV 493 HH +LTE A+ + Q + M+T+ A L + +N QAAM+G+NDIF++S V Sbjct: 471 HHERLTERASVDNPLFNQQIDSTQSLLHMNTQSAHALFDFTVNTQAAMMGLNDIFFVSAV 530 Query: 494 IFLVIIPVIWIIKPAK 509 IF++IIP+IWI +PAK Sbjct: 531 IFILIIPLIWITRPAK 546